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Retina Synthesis

Retina Synthesis
Geographic Atrophy
Diabetic Macular Edema
Neovascular AMD
Diabetic Retinopathy
Aflibercept
Clinical Trials
Artificial Intelligence
Gene Therapy
Retinopathy Of Prematurity
Tyrosine Kinase Inhibitors
Intravitreal Gene Therapy
Stanford University
Home OCT
Photobiomodulation
Age-Related Macular Degeneration
Optogenetics
Ophthalmology
PRIMA Retinal Implant
Visual Acuity
Retina Specialists

Retina Synthesis is a data-focused resource exploring therapies in development for retinal diseases.

PublishesWeeklyEpisodes184Founded5 years ago
Number of ListenersCategory
Education

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Artwork for Retina Synthesis

Latest Episodes

In this episode, we discuss the promising results of intravitreal gene therapy for neovascular AMD with 4D-150 with Dr. Arshad Khanani of Sierra Eye Associates and Clinical Professor of Ophthalmology at the University of Nevada Medical School, Reno.

In this episode, we discuss the latest developments in the use of artificial intelligence in home OCT for management of neovascular AMD with Professor Anat Loewenstein of Tel Aviv Medical Center and President, Israeli Ophthalmology Society.

We discuss long term results of faricimab treatment of DME, with the first author of the Ophthalmology article on the results of Rhone-X trial, Dr. Veeral Sheth, Director of Clinical Research at University Retina in Chicago.

In our latest episode we discuss the results of a novel approach to the treatment of geographic atrophy using Xelafaslatide a Fas inhibitor with Dr. David Zacks, Professor of Ophthalmology at the Kellogg Eye Center at the University of Michigan.

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Recent Guests

Anat Loewenstein
Professor and pioneer in home OCT
Episode: Home OCT in Management of Neovascular AMD
Dr. Veeral Sheth
ophthalmologist discussing the Rhone-X study
Chicago
Episode: Faricimab in the Treatment of DME: Long Term 'Results
David Zacks
Professor, Kellogg Eye Center, University of Michigan
Kellogg Eye Center, University of Michigan
Episode: Xelafaslatide for the Treatment of Geographic Atrophy
Dr. Steven Yeh
Truhlsen Professor at the Truhlsen Eye Institute
University of Nebraska Medical Center
Episode: Inhibition of IL-6 in the Treatment of Retinal Disease
Dr. Mark Barakat
Guest expert discussing the Reclaim-2 trial and related developments
Independent retinal pharmacotherapy expert
Episode: Elamipretide in the Treatment of Geographic Atrophy
Dilsher Dhoot
Eye surgeon with focus on retinal therapies
Santa Barbara, California
Episode: Long Term Followup of Intravitreal Gene Therapy for Neovascular AMD
Dr. Michael Klufas
Ophthalmologist at Wills Eye Hospital
Wills Eye Hospital
Episode: The Port Delivery Stem for Treatment of Neovascular AMD
Jayakrishna Ambati
Gary Professor at the University of Virginia Medical School
University of Virginia
Episode: Kamuvudine 8 in the Treatment of Geographic Atrophy
Adrienne Scott
Professor at Wilmer Eye Institute, Johns Hopkins University
Wilmer Eye Institute, Johns Hopkins University
Episode: Treatment of Proliferative Diabetic Retinopathy After Protocol S

Host

Carmen Puliofito
Host of Retina Synthesis

Reviews

4.8 out of 5 stars from 19 ratings
  • MD PhD

    Great

    Apple Podcasts
    5
    Retina Physician
    United States5 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Engaging hosts with strong clinical credibility.
High-quality synthesis of complex data for practitioners.
Guests provide practical trial insights with real-world relevance.

Top Education Podcasts

Talking Points

Recent interactions between the hosts and their guests.

Faricimab in the Treatment of DME: Long Term 'Results
Q: What is the protocol for starting dose and extension in the current practice?
Historically loading injections were common, but in practice many clinicians now start with monthly injections until dry and then extend by four weeks at a time, extending to 8, 12, or 16 weeks based on response.
Faricimab in the Treatment of DME: Long Term 'Results
Q: How many injections on average do patients have in years three and four of the rollover extension?
Patients received around seven to eight injections across years three and four, roughly three to four injections in year three and about three in year four.
Faricimab in the Treatment of DME: Long Term 'Results
Q: What was the total study period?
The total study period was four years.
Aflibercept 8mg for Retinal Vein Occlusion
Q: In real-world practice, how long do BRVO patients typically require treatment?
BRVO patients often need treatment for six months to a couple of years, with some requiring several years depending on the eye and individual response; the goal is to dry the retina and then extend treatment intervals as tolerated over time.
Aflibercept 8mg for Retinal Vein Occlusion
Q: Tell us about the Quasar study.
The Quasar study was a phase 3 trial evaluating aflibercept 8 mg for retinal vein occlusion, including CRVO, BRVO, and HRVO, with three dosing regimens (2 mg monthly; 8 mg with three loading doses and then every eight weeks; and 8 mg with five loading doses and then every eight weeks), showing comparable efficacy with fewer injections in the higher-dose groups.

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Frequently Asked Questions About Retina Synthesis

What is Retina Synthesis about and what kind of topics does it cover?

Retina Synthesis delivers data-driven conversations focused on therapies in retinal disease development, with frequent deep dives into trial results, mechanisms, and real-world practice. Episodes spotlight geographic atrophy, neovascular AMD, DME, gene therapies, implantable devices, and AI-enabled screening, often pairing clinicians with researchers to unpack what the data implies for patient care, treatment burdens, and future directions. A notable strength is the blend of practical surgical and clinical perspectives with translational science, offering listeners concrete takeaways on trial outcomes, safety signals, and deployment considerations across the retinal field.

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Which podcasts are similar to Retina Synthesis?

These podcasts share a similar audience with Retina Synthesis:

1. New Retina Radio by Eyetube
2. ASRS’s Journal of Vitreoretinal Diseases (JVRD) Author’s Forum
3. The Retina Channel Podcast
4. RETINA Journal Podcasts
5. MedEdTalks - Ophthalmology

How many episodes of Retina Synthesis are there?

Retina Synthesis launched 5 years ago and published 184 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Retina Synthesis?

Recent guests on Retina Synthesis include:

1. Anat Loewenstein
2. Dr. Veeral Sheth
3. David Zacks
4. Dr. Steven Yeh
5. Dr. Mark Barakat
6. Dilsher Dhoot
7. Dr. Michael Klufas
8. Jayakrishna Ambati

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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