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Artwork for MedEvidence! Truth Behind the Data

MedEvidence! Truth Behind the Data

Dr. Michael Koren
Clinical Trials
Clinical Research
Cholesterol
Covid-19
Obesity
Diabetes
Cardiovascular Disease
Heart Disease
Cardiology
Inflammation
Vaccines
Norovirus
Medical Research
Lipoprotein(a)
Flu Season
Statins
Alzheimer's Disease
Healthcare
Atrial Fibrillation
Lipoprotein Little A

Welcome to the MedEvidence! podcast, hosted by Dr. Michael Koren. MedEvidence, where we help you navigate the real truth behind medical research with both a clinical and research perspective. In this podcast, we will discuss with physicians with extensive experience in patient care and research. How do you know that something works? In medicine, we conduct clinical trials to see if things work! No... more

PublishesTwice weeklyEpisodes417Founded4 years ago
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Artwork for MedEvidence! Truth Behind the Data

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What happens when a Harvard-trained psychiatrist follows the evidence beyond traditional medicine?

In this episode of MedEvidence, Dr. Michael Koren sits down with Dr. Carol Locke, physician entrepreneur and Chief Science Officer o... more

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When T.J. Sharpe was diagnosed with stage 4 melanoma at just 37 years old, the statistics were devastating. With a newborn son, a two-year-old daughter, and limited treatment options available at the time, he faced a life-changing d... more

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Watch the recorded presentation of “The Liver Fats Domino Effect” featuring Dr. Mitchell Rothstein and Dr. Michael Koren.

In this educational luncheon event, the speakers discuss how fatty liver disease can progressively worsen ove... more

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Snoring might be the sound you notice, but the real danger of obstructive sleep apnea is what you don’t hear: your brain repeatedly yanking you out of deep sleep to keep you breathing, over and over, all night long. Dr. Mitchell Rot... more

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Recent Guests

Dr. Carol Locke
Psychiatrist, physician entrepreneur
OmegaBrite (OmegaBrite/Ocker Biomarine)
Episode: Can Omega-3s Help Your Brain? What the Research Really Shows
T. J. Sharpe
Cancer survivor who participated in early immunotherapy trials
Patient participant in clinical trials
Episode: From Stage 4 to Survivor: How Clinical Trials Changed One Man’s Life
Javonte Maynor
CEO of Renew Health Clinical Research
Renew Health Clinical Research
Episode: Medical Marijuana is More than Smoke and Mirrors
Derrell Thomas
Patient in a weight-loss clinical study
Episode: Losing Weight, Placebo Or Not
Sean Knight
Radio/Studio guest featured in the segment
Hot 106.5 / Cox Media Group partner studio
Episode: Know Your Numbers: What The Numbers Mean and Why They Matter
Michael Koren
Medical doctor, cardiologist, and research scientist; directs ENCORE Research Group efforts
ENCORE Research Group
Episode: Gene Editing Study For Familial High Cholesterol
Manish Jain
Chicago-based rheumatologist, clinical trialist
Rheumatology practice in Chicago
Episode: What is Gout and How is it Treated?
Dr. Pande
Vascular interventional neurologist, director of the Stroke Center at the HCA Florida Memorial Hospital
HCA Florida Memorial Hospital
Episode: Cholesterol, Blood Pressure, and Stroke. What You Should Know
Robert Pearl
Former CEO of Kaiser Permanente, board-certified plastic surgeon and Stanford faculty
Kaiser Permanente, Stanford University
Episode: The Rising Role of AI in Healthcare

Hosts

Dr. Michael Koren
Cardiologist and research-focused physician, primary host of the show, frequently discussing clinical trials, cardiovascular health, and data interpretation.
Kevin Gettings
Co-host on the MedEvidence network, associated with the MedEvidence Monday Minute format and partner radio shows.

Reviews

5.0 out of 5 stars from 11 ratings
  • Informative and entertaining.

    Podchaser
    5
    med_evidence
    4 years ago
  • Great explanation of complex medical issues

    Dr. Koren explains complex medical information in easy to understand language. Not only is the info knowledge it is also entertaining.

    Apple Podcasts
    5
    JMorrison03
    United States4 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Clear explanations of complex medical topics
Engaging and informative with practical takeaways
Strong guest lineups and data-driven discussions

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Talking Points

Recent interactions between the hosts and their guests.

What Happens When Fat Builds Up in the Liver? The Liver Fats Domino Effect.
Q: How do most people enter the pathway to fatty liver disease if they are asymptomatic?
Most people are asymptomatic initially; the condition is often identified incidentally through imaging or blood tests showing liver enzyme elevations, rather than through symptoms.
What Happens When Fat Builds Up in the Liver? The Liver Fats Domino Effect.
Q: Which of the audience options is the correct answer for why the presentation is called the liver fats domino effect?
The correct answer is that fatty liver disease progresses as dominoes fall—fat accumulation leads to inflammation, fibrosis, and eventually cirrhosis, especially when metabolic risk factors are present.
Can Omega-3s Help Your Brain? What the Research Really Shows
Q: What kind of evidence supported the product's benefits?
Open-label and randomized, placebo-controlled studies in bipolar youth and adults showed mood improvements, reductions in inflammatory markers, and even effects on telomere biology under stress.
Can Omega-3s Help Your Brain? What the Research Really Shows
Q: What set OmegaBrite apart from other omega-3 supplements?
We control the source, distillation, testing, and final formulation, focusing on a precise EPA/DHA ratio and high purity. We also pursued third-party testing to verify label claims and demonstrate consistent quality.
Can Omega-3s Help Your Brain? What the Research Really Shows
Q: How did you transition from practicing psychiatry to running a nutraceutical company?
I saw a clear patient need and, with access to distillation and purification, decided to create a product that met scientific standards. I believed we could bring testing, safety, and proven composition to market faster than a traditional drug path.

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Frequently Asked Questions About MedEvidence! Truth Behind the Data

What is MedEvidence! Truth Behind the Data about and what kind of topics does it cover?

A clinically oriented show that translates complex medical research into practical patient insight, often emphasizing how therapies and trials translate to real-world care. Topics span diabetes reversal strategies, cholesterol management, obesity and metabolic health, hypertension innovations, liver health, and patient-centered healthcare design. Notable for pairing expert clinicians with researchers to explain data behind medical decisions, it often highlights emerging therapies, trial design, and the balance between science and patient experience. Listeners likely include healthcare professionals, students, and engaged patients seeking clarity on how data informs care decisions and policy.

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5. On with Kara Swisher

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MedEvidence! Truth Behind the Data launched 4 years ago and published 417 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on MedEvidence! Truth Behind the Data?

Recent guests on MedEvidence! Truth Behind the Data include:

1. Dr. Carol Locke
2. T. J. Sharpe
3. Javonte Maynor
4. Derrell Thomas
5. Sean Knight
6. Michael Koren
7. Manish Jain
8. Dr. Pande

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