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Artwork for Major Pain

Major Pain

Jesse Mercury
Chronic Illness
Mental Health
Self-Advocacy
Chronic Pain
Medical Gaslighting
Community Support
Mast Cell Activation Syndrome
Ehlers-Danlos Syndrome
Fibromyalgia
Epilepsy
Bipolar Disorder
Rheumatoid Arthritis
Neonatal Abstinence Syndrome
Multiple Sclerosis
Patient Advocacy
Systemic Juvenile Idiopathic Arthritis
Disability
Visual Snow Syndrome
General Pustular Psoriasis
Chronic Illness Advocacy

The Major Pain podcast is a collection of interviews from people living with chronic illness and disability. Our goal is to spread awareness, empathy and community around experiences often lived through in isolation. Through sharing these stories important themes have become increasingly apparent, including the dangers of medical gaslighting, the importance of self-advocacy and the fact that none ... more

PublishesMonthlyEpisodes207Founded5 years ago
Number of ListenersCategory
Health & Fitness

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Artwork for Major Pain

Latest Episodes

What does “body positivity” mean to you? To Kelvin Davis, it began as a gap in the market. Women’s clothing advertising was leaning, more and more, into diversity in their models, while menswear seemed content to maintain the status quo of ultra-ripp... more

YouTube

How do you live with the ever-looming uncertainty of being a gene carrier for a fatal disease? Amyotrophic lateral sclerosis—better known as ALS or Lou Gehrig’s disease—was long believed not to be genetic. Today, however, research shows that 10-15% o... more

YouTube

Pointing to Edward’s first symptom of Relapse–Remitting MS is tricky. From anxiety in his 20s, to poor sleep and numb hands, to back pain and difficulty walking, the road to diagnosis has been rocky. When he finally received confirmation—in the form ... more

YouTube

Katie Brennan’s experience with Long COVID began in the earliest days of the pandemic, while she was working with the UK’s National Health Service on data-driven policy changes to improve care for patients. Though her experience with the acute phase ... more

YouTube

Key Facts

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Recent Guests

Kelvin Davis
Content creator, author, and model
Notoriously Dapper / Be a Good Man, Not a Nice Guy (book titles)
Episode: Love Your Body, Own Your Health: Discussing Type II Diabetes with Kelvin Davis
Mindy Uhrlaub
ALS activist, author, genetic carrier of ALS/FTD
End the Legacy
Episode: The Knowledge to Live Better: ALS, Advocacy, and Acceptance with Mindy Uhrlaub
Katie Brennan
Founder of ThriveNinety
ThriveNinety
Episode: Long COVID to Long-Term Wellness: Katie Brennan’s Journey to Build ThriveNinety
Justin Goodman
Subject of the episode; advocate and founder of Project 55
Project 55
Episode: From Scheuermann’s Disease to Project 55: Justin Goodman’s Incredible Story
Tim Cummings
Author of The Lightening People Play
Episode: Author Tim Cummings on How His Brother’s Epilepsy Shaped His New Novel
Anthony Lucero
Writer, director, producer, editor of Paper Bag Plan
Episode: Heartfelt Indie Film ‘The Paper Bag Plan’ Features Authentic Disability Representation
Cole Massie
Lead actor in Paper Bag Plan
Episode: Heartfelt Indie Film ‘The Paper Bag Plan’ Features Authentic Disability Representation
Michelle Massie
Mother of Cole Massie and supporter of the film
Episode: Heartfelt Indie Film ‘The Paper Bag Plan’ Features Authentic Disability Representation
Tara Sundem
Executive director and founder of Hushaybe Nursery, a facility that supports newborns affected by opiate withdrawal.
Hushabye Nursery
Episode: A Novel Approach to Neonatal Abstinence Syndrome

Host

Jesse Mercury
Host of Major Pain

Reviews

5.0 out of 5 stars from 116 ratings
  • Please continue

    Your show means so much to me. It is at least the one place I feel seen. Please keep going it is a tremendous help. Thank you Sue

    Apple Podcasts
    5
    555387654
    United States2 years ago
  • Enjoying this so much

    Found this podcast during a time in my life where I really need it. Jesse, you are such an incredible, relatable host - you really have a gift for connecting with people and providing a space for folks to tell their stories. A big thanks to you and all the guests for sharing your stories and helping us know we are not alone.

    Apple Podcasts
    5
    Emma Eileen
    United States2 years ago
  • I love your podcast!

    Please keep doing this podcast, it is so informative and as somebody with a chronic illness I so appreciate listening to all the stories, it creates awareness for supposedly invisible illness that I don’t feel ever are invisible… at least not mine. ❤️

    Apple Podcasts
    5
    jjulius2008
    United States2 years ago
  • v important

    great show. The episode with raven was especially poignant and impactful, will share with me mum

    Apple Podcasts
    5
    Zac 2077
    United States3 years ago
  • Please continue

    I love your show and I would more that miss it. Knowing your not the only ones going thru these problems is so helpful. Jessie you mean so much to us all thanks Sue

    Apple Podcasts
    5
    555387654
    United States3 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Listeners praise compassionate, relatable conversations that validate lived experiences.
Episodes are seen as educational, reducing feelings of isolation for chronic illness communities.
The host's empathy and openness help guests share difficult stories honestly.
Overall sentiment highlights impact, support, and community-building through storytelling.
Audience notes accessibility and meaningful discussions beyond typical illness coverage.

Talking Points

Recent interactions between the hosts and their guests.

The Knowledge to Live Better: ALS, Advocacy, and Acceptance with Mindy Uhrlaub
Q: How has learning about your gene changed your life and how you approach your children?
Knowing she carries the gene has shaped decisions about family planning, IVF, donor options, and adoption, while also motivating protective health choices and active participation in research.
The Knowledge to Live Better: ALS, Advocacy, and Acceptance with Mindy Uhrlaub
Q: What is your major pain?
Her major pain is the specter of a fatal disease and the accompanying grief and worry, but she channels that into advocacy and practical steps to live with the disease.
Hidradenitis Suppurativa: Parish’s Path to Acceptance
Q: If you could have never had HS, would you make that choice?
No, because I see what I've been through and how much it's helped me...
Hidradenitis Suppurativa: Parish’s Path to Acceptance
Q: How old were you when the first signs of HS started to appear?
First signs, I was like seven years old.
Hidradenitis Suppurativa: Parish’s Path to Acceptance
Q: Parish, what is your major pain?
My major pain is hydratinitis superativa.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
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Frequently Asked Questions About Major Pain

What is Major Pain about and what kind of topics does it cover?

A human-centered interview series focused on lived experiences with chronic illness and disability. Across episodes, the show highlights medical gaslighting, patient advocacy, resilience, and practical strategies for managing daily life with illness. Notable angles include genetic testing, advocacy through community networks, and the role of personal narratives in shaping awareness and support for marginalized health journeys. The format tends to feature personal storytelling, with guests ranging from patients and caregivers to advocates and creators, offering both emotional insight and actionable takeaways for listeners.

Where can I find podcast stats for Major Pain?

Rephonic provides a wide range of podcast stats for Major Pain. We scanned the web and collated all of the information that we could find in our comprehensive podcast database. See how many people listen to Major Pain and access YouTube viewership numbers, download stats, audience demographics, chart rankings, ratings, reviews and more.

How many listeners does Major Pain get?

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What are the audience demographics for Major Pain?

Rephonic provides comprehensive predictive audience data for Major Pain, including gender skew, age, country, political leaning, income, professions, education level, and interests. You can access these listener demographics by upgrading your account.

How many subscribers and views does Major Pain have?

To see how many followers or subscribers Major Pain has on Spotify and other platforms such as Castbox and Podcast Addict, simply upgrade your account. You'll also find viewership figures for their YouTube channel if they have one.

Which podcasts are similar to Major Pain?

These podcasts share a similar audience with Major Pain:

1. The Dizzy Diaries
2. eanCast: Weekly Neurology

How many episodes of Major Pain are there?

Major Pain launched 5 years ago and published 207 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact Major Pain?

Our systems regularly scour the web to find email addresses and social media links for this podcast. We scanned the web and collated all of the contact information that we could find in our podcast database. But in the unlikely event that you can't find what you're looking for, our concierge service lets you request our research team to source better contacts for you.

Where can I see ratings and reviews for Major Pain?

Rephonic pulls ratings and reviews for Major Pain from multiple sources, including Spotify, Apple Podcasts, Castbox, and Podcast Addict.

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What guests have appeared on Major Pain?

Recent guests on Major Pain include:

1. Kelvin Davis
2. Mindy Uhrlaub
3. Katie Brennan
4. Justin Goodman
5. Tim Cummings
6. Anthony Lucero
7. Cole Massie
8. Michelle Massie

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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