
The Major Pain podcast is a collection of interviews from people living with chronic illness and disability. Our goal is to spread awareness, empathy and community around experiences often lived through in isolation. Through sharing these stories important themes have become increasingly apparent, including the dangers of medical gaslighting, the importance of self-advocacy and the fact that none ... more
| Publishes | Monthly | Episodes | 207 | Founded | 5 years ago |
|---|---|---|---|---|---|
| Number of Listeners | Category | Health & Fitness | |||

What does “body positivity” mean to you? To Kelvin Davis, it began as a gap in the market. Women’s clothing advertising was leaning, more and more, into diversity in their models, while menswear seemed content to maintain the status quo of ultra-ripp... more
How do you live with the ever-looming uncertainty of being a gene carrier for a fatal disease? Amyotrophic lateral sclerosis—better known as ALS or Lou Gehrig’s disease—was long believed not to be genetic. Today, however, research shows that 10-15% o... more
Pointing to Edward’s first symptom of Relapse–Remitting MS is tricky. From anxiety in his 20s, to poor sleep and numb hands, to back pain and difficulty walking, the road to diagnosis has been rocky. When he finally received confirmation—in the form ... more
Katie Brennan’s experience with Long COVID began in the earliest days of the pandemic, while she was working with the UK’s National Health Service on data-driven policy changes to improve care for patients. Though her experience with the acute phase ... more
Your show means so much to me. It is at least the one place I feel seen. Please keep going it is a tremendous help. Thank you Sue
Found this podcast during a time in my life where I really need it. Jesse, you are such an incredible, relatable host - you really have a gift for connecting with people and providing a space for folks to tell their stories. A big thanks to you and all the guests for sharing your stories and helping us know we are not alone.
Please keep doing this podcast, it is so informative and as somebody with a chronic illness I so appreciate listening to all the stories, it creates awareness for supposedly invisible illness that I don’t feel ever are invisible… at least not mine. ❤️
great show. The episode with raven was especially poignant and impactful, will share with me mum
I love your show and I would more that miss it. Knowing your not the only ones going thru these problems is so helpful. Jessie you mean so much to us all thanks Sue
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Recent interactions between the hosts and their guests.
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A human-centered interview series focused on lived experiences with chronic illness and disability. Across episodes, the show highlights medical gaslighting, patient advocacy, resilience, and practical strategies for managing daily life with illness. Notable angles include genetic testing, advocacy through community networks, and the role of personal narratives in shaping awareness and support for marginalized health journeys. The format tends to feature personal storytelling, with guests ranging from patients and caregivers to advocates and creators, offering both emotional insight and actionable takeaways for listeners.
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Major Pain launched 5 years ago and published 207 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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Recent guests on Major Pain include:
1. Kelvin Davis
2. Mindy Uhrlaub
3. Katie Brennan
4. Justin Goodman
5. Tim Cummings
6. Anthony Lucero
7. Cole Massie
8. Michelle Massie
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