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Extend Podcast with Darshan Shah, MD

Darshan Shah, MD
Nutrition
Metabolic Health
Mental Health
Functional Medicine
Longevity
Chronic Disease
Healthspan
Brain Health
Gut Health
Exercise
Women's Health
Aging
Gut Microbiome
Heart Disease
Health Optimization
Obesity
Inflammation
Sleep
Strength Training
Gut-Brain Connection

Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan. Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified sur... more

PublishesTwice weeklyEpisodes163Founded2 years ago
Number of ListenersCategories
MedicineNutritionHealth & Fitness

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Artwork for Extend Podcast

Latest Episodes

A lot of people are walking around exhausted, foggy, moody, and struggling with their cardiovascular health blaming stress, diet, age, and everything in between, never once considering that the real culprit might be happening in the eight hours they ... more

Fatigue, brain fog, weight gain, hair loss, low libido, high cholesterol, and a doctor who keeps telling you your labs look normal. For the millions of people walking around with an undetected or poorly managed thyroid condition, this is not just a f... more

Biological aging is no longer just a concept tied to time. It is something we can now measure, track, and influence through data, lifestyle, and targeted interventions that directly impact how our cells function and age.

In this episode of Extend, ... more

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Mitochondrial decline is one of the most overlooked drivers of aging, impacting energy, muscle function, cognitive performance, and immune resilience long before symptoms become obvious. Many of the changes we associate with aging may actually stem f... more

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Recent Guests

Dr. Kara Fitzgerald
Naturopathic doctor and leading researcher in epigenetics
Next Health advisor; researcher on epigenetics and aging
Episode: 160. Dr. Kara Fitzgerald on Biological Age, Epigenetic Clocks, and the Future of Aging Reversal
Anurag Singh
MD, PhD; physician and scientist focused on mitochondrial health
Timeline/Mitopure
Episode: 159: Dr. Anurag Singh: Urolithin A, Mitophagy, and Mitochondrial Health
Kavin Mistry
Neuroradiologist, longevity educator, author of Primal Health Design
Primal Health Design / Primal Health Design book
Episode: 158. Dr. Kavin Mistry: Primal Health Design, Biological Aging, and Reconnecting with Human Biology
Dr. Tania Elliott
Double board-certified internal medicine and allergy/immunology physician
Private practice; immunology and allergy expert
Episode: 157. Dr. Tania Elliott: Allergies, Immune Health, and Hidden Toxins in Your Home
Judith Joseph
Board-certified psychiatrist, researcher, author of High Functioning
Book author; researcher; psychiatrist
Episode: 156. Dr. Judith Joseph: High-Functioning Depression, Anhedonia, and Reclaiming Joy
Dr. Eboni Cornish
Associate Medical Director at Amen Clinics; President-Elect of ILADS; specializes in neuroinflammation and brain imaging
Amen Clinics; ILADS
Episode: 155. Dr. Eboni Cornish: Neural Longevity, Brain Inflammation, and the Hidden Root Causes of Mental Health Symptoms
Nick Norwitz
Metabolic health researcher and physician scientist
Stay Curious Metabolism (newsletter)
Episode: 152. Nick Norwitz: Cholesterol Myths, Insulin Resistance, and the Real Drivers of Heart Disease
Ramses Alcaide
Co-founder/CEO at Neurable
Neurable
Episode: 151. Ramses Alcaide: Brain Wearables, EEG, and the Future of Brain Health Tracking
Terry Grossman
Physician and pioneer in longevity medicine; founder of Grossman Wellness Center
Grossman Wellness Center
Episode: 150. Dr. Terry Grossman: Plasma Exchange, Detoxification, and the Future of Longevity Medicine

Host

Darshan Shah
Host of Extend Podcast with Darshan Shah, MD

Reviews

4.8 out of 5 stars from 210 ratings
  • Best podcast for your health!

    I always learn something useful for my health. Love your episodes that give newest technology, tests,etc., so we can better manage our health. Episode 118 was one of my favorites as it answered many questions for me but have enjoyed all of them.

    Apple Podcasts
    5
    Zumba LAK
    United States10 days ago
  • Steve Gundry

    A Consumate Charlatan

    Apple Podcasts
    1
    Egonzzzzzzzz
    United States5 months ago
  • Obsessed with this podcast

    High calibre but accessible, scientifically grounded information. This is one of my new favourite podcasts.

    Apple Podcasts
    5
    Slgarcia84
    Canada7 months ago
  • Fantastic. Highly recommend.

    About time mainstream medicine pushes the envelope. So thankful Dr. Shah is taking lead and tackling optimal/preventative health. Great insights.

    Apple Podcasts
    5
    arleach
    United States8 months ago
  • Episode 86

    Generally great info. But please have Dr Tracey Strouo correct her verbiage. She calls bacterioststic water the”bacteria water”

    Apple Podcasts
    4
    LVAngTay
    United States9 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Guests bring high-level expertise and real-world applications for longevity and healthspan.
Insightful, evidence-based discussions that push toward practical health optimization.
Content blends rigorous science with approachable protocols and patient stories.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

159: Dr. Anurag Singh: Urolithin A, Mitophagy, and Mitochondrial Health
Q: What makes urolithin A stand out among mitochondrial-focused interventions?
Urolithin A uniquely activates mitophagy, initiating clearance of damaged mitochondria and enabling the formation of healthier mitochondria, a mechanism distinct from direct biogenesis stimulators or energy-supply cofactors, which may explain its broad effects on muscle, immune, and brain health.
155. Dr. Eboni Cornish: Neural Longevity, Brain Inflammation, and the Hidden Root Causes of Mental Health Symptoms
Q: What is neural longevity and why is imaging important?
Neural longevity is about actively maintaining brain health throughout life by addressing root causes—like infections, hormonal changes, sleep issues, and inflammation—using imaging (SPECT) to guide targeted interventions rather than relying solely on traditional symptom-based approaches.
148. Fitz Koehler: The Four Pillars of Fitness and the Exact Formula for Strength, Fat Loss, and Longevity
Q: How should a beginner start getting back into exercise after a hiatus?
Begin with what you enjoy, start at your current level, and gradually incorporate all four pillars—strength, cardio, flexibility, and balance—while keeping a simple, sustainable plan.
148. Fitz Koehler: The Four Pillars of Fitness and the Exact Formula for Strength, Fat Loss, and Longevity
Q: What are two to three big pieces of advice for someone going through cancer treatment or recovery?
Prioritize what you can control, keep moving with suitable exercise, and focus on discipline and consistency over motivation to maintain progress and rebuild strength.
145. Dr. Dave Rabin: HRV, Vagal Tone, and the Science of Safety for Performance and Mental Health
Q: What are the practical metrics to watch beyond traditional biomarkers, and how can individuals start using HRV in daily life?
HRV offers a real-time glimpse into vagal tone and recovery potential. Start with a baseline over a month, then use micro-breathing moments (2–5 minutes) to bump HRV and signal safety, rather than chasing perfect data. Emphasize environment and small, repeatable breathing decisions to train the nervous system.

Audience Metrics

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Frequently Asked Questions About Extend Podcast

What is Extend Podcast about and what kind of topics does it cover?

A cutting-edge health and longevity show featuring physicians, researchers, and health-tech leaders who share practical protocols to extend healthspan. Across episodes, topics span cholesterol and cardiometabolic risk, brain health and wearables, longevity therapies, gut and mold toxicity, fertility and menopause, vaccines and pediatric nutrition, fitness optimization, and nervous-system approaches to mental well-being. The conversations mix rigorous science with real-world applications, patient stories, and actionable takeaways, making complex biomedical advances accessible for listeners who want to improve daily health, performance, and resilience. A standout throughline is integrating diverse medical systems and technologies to empower p... more

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Which podcasts are similar to Extend Podcast?

These podcasts share a similar audience with Extend Podcast:

1. Feel Better, Live More with Dr Rangan Chatterjee
2. The Dr. Hyman Show
3. Dhru Purohit Show
4. The Doctor's Kitchen Podcast
5. The Dr. Gabrielle Lyon Show

How many episodes of Extend Podcast are there?

Extend Podcast launched 2 years ago and published 163 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Extend Podcast?

Recent guests on Extend Podcast include:

1. Dr. Kara Fitzgerald
2. Anurag Singh
3. Kavin Mistry
4. Dr. Tania Elliott
5. Judith Joseph
6. Dr. Eboni Cornish
7. Nick Norwitz
8. Ramses Alcaide

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