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Behind the Breakthroughs

Inside Precision Medicine
Precision Medicine
CAR T-Cell Therapy
Oncology
Clinical Trials
Artificial Intelligence
Molecular Diagnostics
Molecular Pathology
Emily Whitehead Foundation
Cancer Detection
Genomics
Natural Killer Cells
Next-Generation Sequencing
Biotechnology
Cell and Gene Therapy
Genomic Testing
FDA
CRISPR
Gene Editing
Healthcare
Pediatric Cancer

Join host Jonathan D. Grinstein, PhD, North American Editor for Inside Precision Medicine, as he uncovers the stories behind the pioneers driving the precision medicine revolution. Behind the Breakthroughs features candid interviews with seasoned veterans and rising stars, exploring their origin stories and groundbreaking contributions advancing the frontiers of patient diagnosis, treatment, and c... more

PublishesTwice monthlyEpisodes26Founded10 months ago
Number of ListenersCategories
TechnologyScience

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Artwork for Behind the Breakthroughs

Latest Episodes

Shana Kelley, PhD, embraces bold, science-fiction-like challenges, such as developing real-time technologies to monitor immune activity—work that demands cross-disciplinary expertise, flexible funding, and visionary leadership. As a Professor at Nort... more

Mara Aspinall has long been a leader in precision medicine, championing diagnostics as vital to better treatments and saving lives. She built Genzyme Genetics into the nation’s top testing business, later acquired by LabCorp for $1 billion, and led V... more

David R. Liu, PhD, Harvard and Broad Institute professor, invented base and prime editing—gene editing tools now in 20+ clinical trials with early wins against sickle cell, leukemia, and more. Founder of Editas, Beam, and Prime Medicine, and winner o... more

Janice Chen, PhD, helped transform CRISPR from a lab discovery into a life-saving tool. As co-founder of Mammoth Biosciences with Jennifer Doudna, Trevor Martin, and Lucas Harrington, she’s driven efforts to harness CRISPR for human health and diagno... more

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Recent Guests

Kate Sasser
Chief Scientific Officer at Tempus
Tempus
Episode: Kate Sasser: How Lab-in-the-loop Turns Patient Data Into Patient Care
Kian Sadeghi
Young entrepreneur and founder of Nucleus Genomics with a passion for personalized genomics
Nucleus Genomics
Episode: Kian Sadeghi: Is Personalized Genomics Undergoing a Direct-to-Consumer Renaissance?
Carlos Bustamante
World-renowned population geneticist
Galatea Bio
Episode: Carlos D. Bustamante: Latin American Diversity’s Genetic Potential
Josh Denny
CEO of the All of Us Research Initiative
National Institutes of Health (NIH)
Episode: Josh Denny: The Future of Precision Public Health
Uli Stilz
Vice President at Novo Nordisk and founder of the Bio Innovation Hub in Boston
Novo Nordisk
Episode: Uli Stilz: Conquering Complex Diseases Affecting Billions with Precision Medicine
Dr. Thomas Beer
Chief Medical Officer for Multicancer Early Detection at Exact Sciences
Exact Sciences
Episode: Tomasz (Tom) Beer: Detecting Cancer Before Symptoms? Multicancer Early Detection Leads the Way
Dr. Katy Rezvani
Prominent figure in the cell therapy field at the University of Texas, MD Anderson Cancer Center
MD Anderson Cancer Center
Episode: Katy Rezvani: Allogeneic NK Cells Are Coming to Beat Cancer at a Clinic Near You
Dr. Toby Ferguson
Chief Medical Officer at Voyager Therapeutics
Voyager Therapeutics
Episode: Toby Ferguson: From Bloodstream to Brain: Accessing the Neurogenetic Medicine Revolution
Dr. Tomi Pastinen
Director of the Center for Pediatric Genomic Medicine at Children's Mercy Kansas City
Children's Mercy Kansas City
Episode: Tomi Pastinen: Treating All the Not-So-Rare “Rare Disease” Patients at Major Care Centers

Host

Jonathan D. Grinstein
Host and North American Editor at Inside Precision Medicine.

Chart Rankings

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Apple Podcasts
#240
Spain/Technology

Talking Points

Recent interactions between the hosts and their guests.

Kate Sasser: How Lab-in-the-loop Turns Patient Data Into Patient Care
Q: How do you define real world data?
Real world data comes directly from patients, physicians, and healthcare systems, integrated with electronic medical records.
Kate Sasser: How Lab-in-the-loop Turns Patient Data Into Patient Care
Q: Can you tell me a little bit about that or at least how you think about that?
Precision medicine is the first step along a continuum that can hopefully lead us to personalized medicine.
Geoff Oxnard: The Tipping Point for Adopting Precision Medicine
Q: What has been your approach to help adopt precision oncology in this case, everywhere that it can reach?
Dr. Oxnard mentioned that he invests in research collaborations and works with patient advocacy groups to educate both clinicians and patients on the importance of precision medicine.
Geoff Oxnard: The Tipping Point for Adopting Precision Medicine
Q: What got you on the path that you are on now?
Dr. Oxnard shared that his interest in precision medicine began during his medical training, particularly in oncology fellowship when genetic testing started to evolve.
Helen Sabzevari: How to Turn $1,000,000 CAR Ts into “Real” Precision Medicines
Q: Can you share what attracted you to Precigen and your journey into the field of cell and gene therapy?
Dr. Sabzevari shares her background in immuno-oncology and the need for scalable solutions in cell and gene therapy, emphasizing the importance of developing accessible treatments for patients.

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Frequently Asked Questions About Behind the Breakthroughs

What is Behind the Breakthroughs about and what kind of topics does it cover?

Candid interviews with pioneers in the field highlight the astonishing advances in precision medicine, showcasing the personal and professional journeys of industry leaders disrupting traditional healthcare concepts. The discussions primarily focus on the integration of emerging technologies, such as molecular diagnostics, next-generation sequencing, and artificial intelligence, in advancing patient diagnostics, treatment, and care. Episodes feature insights from experts across various sectors, including healthcare, biotechnology, and genomics, delving into how they are working towards making innovative therapies equitable and accessible to diverse patient populations. This exploration of both groundbreaking scientific advancements and the ... more

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Which podcasts are similar to Behind the Breakthroughs?

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1. The Readout Loud
2. Biotech Hangout
3. No Priors: Artificial Intelligence | Technology | Startups
4. Odd Lots
5. BioCentury This Week

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Behind the Breakthroughs launched 10 months ago and published 26 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Behind the Breakthroughs?

Recent guests on Behind the Breakthroughs include:

1. Kate Sasser
2. Kian Sadeghi
3. Carlos Bustamante
4. Josh Denny
5. Uli Stilz
6. Dr. Thomas Beer
7. Dr. Katy Rezvani
8. Dr. Toby Ferguson

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