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The Readout Loud

STAT
FDA
Eli Lilly
Novo Nordisk
Biotechnology
Pfizer
Gene Therapy
Covid-19
Duchenne Muscular Dystrophy
CRISPR
RFK Jr.
Vertex Pharmaceuticals
Sarepta Therapeutics
Moderna
Drug Pricing
Biotech
Obesity
Astrazeneca
Obesity Drugs
Cancer Treatments
Drug Development

STAT’s weekly biotech podcast, breaking down the latest news, digging deep into industry goings-on, and giving you a preview of the week to come.

PublishesWeeklyEpisodes406Founded8 years ago
Number of ListenersCategory
Business

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Artwork for The Readout Loud

Latest Episodes

This week’s episode of “The Readout LOUD” is all about health politics.

We bring on FDA reporter Lizzy Lawrence to discuss Makary’s departure — why he is leaving, which of his policies will stick, and what we know about his acting replacement, Kyle ... more

On this week’s episode of "The Readout LOUD," we chat with Seaport Therapeutics CEO Daphne Zohar, fresh off the biotech’s successful IPO.

Plus, Elaine, Allison, and Adam chat about this week’s notable news, including the obesity pill battle between ... more

Why are investors excited about hair loss drugs? Will artificial intelligence make clinical trials run more smoothly? And how does a nonprofit pharma company compete in the M&A arena?

We get into all that and more on this week’s episode of “The Read... more

How did a biotech company that almost ran out of money three times get acquired for over $3 billion? Will the M&A streak continue? And why are drugmakers working with a telehealth company called Prescribery?

We discuss all that and more on this week... more

Key Facts

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Find out how many people listen to this podcast per episode and each month.

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Recent Guests

Chelsea Cirruzzo
STAT reporter covering health policy and Congress
STAT
Episode: 401: Makary’s departure and Cassidy’s tenuous Senate seat
Daphne Zohar
Co-founder and CEO of Seaport Therapeutics
Seaport Therapeutics
Episode: 400: Seaport's IPO adventure, obesity pill battles, and Makary's troubles
Reid Waldman
CEO, Veradermics
Veradermics
Episode: 399: Hair-raising trial results, and Servier’s M&A wishlist
David Lee
CEO, Servier Pharmaceuticals US
Servier
Episode: 399: Hair-raising trial results, and Servier’s M&A wishlist
Preeti Hegde
Senior Vice President and Global Head of Research
Kite, a Gilead company
Episode: 399: Hair-raising trial results, and Servier’s M&A wishlist
Bryan Roberts
Partner at Venrock, investor in Kelonia
Venrock
Episode: 398: A CAR-T biotech's dramatic turnaround, and drugmakers' tactics to drive more scripts
Zach Roberts
Chief Medical Officer, Allogene Therapeutics
Allogene Therapeutics
Episode: 397: A pancreatic cancer breakthrough, and new hope for an off-the-shelf CAR-T treatment
Paul Oberstein
Pancreatic cancer expert from NYU Langone
NYU Langone
Episode: 397: A pancreatic cancer breakthrough, and new hope for an off-the-shelf CAR-T treatment
Rod Wong
Managing partner at RTW Investments, biotech investment fund
RTW Investments
Episode: 395: Biotech investors' plea to Trump, and a busy M&A week

Hosts

Adam Feuerstein
Host of The Readout Loud.
Allison DeAngelis
Host of The Readout Loud.
Elaine Chen
Host of The Readout Loud.

Reviews

4.7 out of 5 stars from 588 ratings
  • Constructive Feedback on Episode 398

    Hey STAT Team - As a long time reader and biotech CEO, I wanted to pass on hopefully constructive feedback on your show in general and this specific episode. I really enjoyed hearing the inside scoop from Bryan Roberts on Kelonia and the Lilly deal. That was great. Please do more of that! In the constructive feedback category, the one thing that I would caution you on, both in this episode and others, is the trivial nature (joking, in fact) in how you handle very, very tough times for these comp... more

    Apple Podcasts
    3
    DP75007
    United States24 days ago
  • David Olson

    Thoughtful and concise discussion about drug development processes. I found this illuminating

    and hopeful

    Apple Podcasts
    5
    Auldkirk
    United Kingdom5 months ago
  • Really informative and relevant

    Great coverage by the three hosts.

    Only area of improvement is if the audio editor can adjust the volume for all speakers to be equal because for some reason Elaine’s mic tends to be the loudest and I have to keep adjusting the volume for each speaker.

    Apple Podcasts
    4
    orange03$592
    United States6 months ago
  • Great pod!

    This is a great overview of the biopharm space with an engaging and fun style. I also like the unrelated chat amongst the team, particularly as a fellow fan of the Great British Bake Off, given this is an industry that can often take itself very seriously!

    Apple Podcasts
    5
    123etcetc
    United Kingdom7 months ago
  • Please reboot the old quality bar

    This podcast was a gold mine a few years back. Really miss that run you had. Adam is good but even he was better back when surrounded with higher caliber cohosts.

    Apple Podcasts
    3
    freedomtochoose
    United States8 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Thoughtful and concise discussion about drug development processes.
Quality content but some listeners feel hosts could improve articulation skills.
Engaging and fun style; informative coverage of the biopharm space.
Critique of political undertones in discussions.
Broadly relevant for biotechnology news and updates.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#180
Sweden/Business
Apple Podcasts
#219
Switzerland/Business

Talking Points

Recent interactions between the hosts and their guests.

400: Seaport's IPO adventure, obesity pill battles, and Makary's troubles
Q: Daphne, welcome back to the podcast. Was it exhausting? Have you recovered? What was it like going through an IPO while personally involved in a major event?
It's been a crazy few weeks with a serious car crash, but the focus on the IPO and Seaport's mission helped keep things in perspective. Despite personal challenges, she emphasizes perseverance, team support, and staying committed to the mission of improving mental health through new medicines.
398: A CAR-T biotech's dramatic turnaround, and drugmakers' tactics to drive more scripts
Q: Do you think the valuation and upfront payment reflect the risk profile of Kelonia's program?
The $3.25 billion upfront, with potential milestones, reflects the combination of pent-up demand for in vivo CAR-T platforms, the strategic fit with Lilly's pipeline, and the scalability upside if durability holds with larger patient populations, despite the early stage of data.
398: A CAR-T biotech's dramatic turnaround, and drugmakers' tactics to drive more scripts
Q: Bryan, what was the key driver for Lilly's interest in Kelonia after Ash, and how did the negotiation unfold?
Lilly was drawn by the durable data showing deep responses and MRD negativity, the potential to expand an obesity-drug revenue franchise via a big CAR-T platform, and a favorable risk/return profile given their portfolio. Negotiations gradually ramped up over several months as Lilly built comfort with the team, data quality, and manufacturing.
397: A pancreatic cancer breakthrough, and new hope for an off-the-shelf CAR-T treatment
Q: How do you respond to the question of front-line vs. relapse treatment, and could semicell potentially replace autologous CAR-T in some settings?
If efficacy and safety hold up, semicell could offer comparable event-free survival with a much more accessible treatment paradigm, enabling administration in infusion clinics rather than hospitals and expanding access for the 85% of patients who currently cannot reach autologous CAR-T therapy.
397: A pancreatic cancer breakthrough, and new hope for an off-the-shelf CAR-T treatment
Q: Tell us what you can glean from these results. What do these results mean?
The interim futility analysis supports the core hypothesis that eradicating minimal residual disease could translate into improved event-free survival, potentially matching outcomes seen with approved CAR-T therapies in relapsed disease, while offering an outpatient, community-friendly approach.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
Professions
Age Range
Household Income
Social Media Reach

Frequently Asked Questions About The Readout Loud

What is The Readout Loud about and what kind of topics does it cover?

This weekly podcast provides insightful analyses and discussions on the latest developments in the biotechnology industry, covering significant news, regulatory challenges, and the interplay between pharmaceutical companies and the government. Each episode features hosts breaking down complex topics such as drug pricing, the implications of FDA decisions, and new treatments in the biotech sphere, making it accessible for both industry insiders and curious listeners alike. Besides focusing on major companies like Novo Nordisk and Eli Lilly, the dialogue often touches on broader societal themes, including patient advocacy and public health, engaging a diverse audience interested in medicine's future.

Unique for its expert guests and engaging... more

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Which podcasts are similar to The Readout Loud?

These podcasts share a similar audience with The Readout Loud:

1. BioCentury This Week
2. Biotech Hangout
3. The Long Run with Luke Timmerman
4. Raising Health
5. What the Health? From KFF Health News

How many episodes of The Readout Loud are there?

The Readout Loud launched 8 years ago and published 406 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Readout Loud?

Recent guests on The Readout Loud include:

1. Chelsea Cirruzzo
2. Daphne Zohar
3. Reid Waldman
4. David Lee
5. Preeti Hegde
6. Bryan Roberts
7. Zach Roberts
8. Paul Oberstein

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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