Rephonic
Artwork for The Long Run

The Long Run with Luke Timmerman

Timmerman Report
Biotechnology
Sickle Cell Disease
Cancer
AI In Drug Discovery
Cancer Research
Drug Discovery
ARTIFICIAL INTELLIGENCE
Clinical Trials
Parkinson's Disease
Alzheimer's Disease
Precision Medicine
Biotech
Immunotherapy
CAR T Cell Therapy
Neuron23
CRISPR
Machine Learning
Healthy Aging
Single-Cell Genomics
RNA Interference

"The Long Run" Antarctic explorer Ernest Shackleton would appreciate today's biotech. Scientific entrepreneurs of the 21st century must be ready for what Shackleton called the “hazardous journey, bitter cold, long months of complete darkness, constant danger, safe return doubtful, honor and recognition in case of success.” Today, the men and women who strive to apply science for the betterment of ... more

PublishesTwice monthlyEpisodes204Founded9 years ago
Number of ListenersCategory
Science

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Artwork for The Long Run

Latest Episodes

Lyn Baranowski, CEO of Boston-based Avalyn Pharma, on developing inhalable medicines for severe lung diseases.

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Heather Turner, CEO of New York-based LB Pharma, on developing a new schizophrenia drug designed to better cross the blood-brain barrier, be dosed once daily, and make it easier for patients to take long term.

Troy Wilson, CEO of San Diego-based Kura Oncology, on his career in biotech and developing targeted cancer drugs.

Sri Kosuri, co-founder and CEO of Emeryville, Calif.-based Octant Bio, on small molecules designed to correct protein misfolding and mistrafficking at the root of many diseases.

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Recent Guests

Heather Turner
CEO of LB Pharmaceuticals
LB Pharmaceuticals
Episode: Ep205: Heather Turner on a Schizophrenia Drug Patients Can Stick With
Troy Wilson
CEO and co-founder of Kura Oncology
Kura Oncology
Episode: Ep204: Troy Wilson on Precision Cancer Drugs and Combos
Sri Kosuri
CEO and co-founder of Octant Bio
Octant Bio
Episode: Ep203: Sri Kosuri on Small Molecule Correctors of Disease
Becky Pferdehirt
CEO of Radial, life sciences portfolio of the Astera Institute
Astera Institute / Radial
Episode: Ep202: Becky Pferdehirt on Reimagining Science for the AI Era
Jeremy Levin
Executive Chairman and Founder of Ovid Therapeutics
Ovid Therapeutics
Episode: Ep201: Jeremy Levin on Biotech in the Balance
Richard Pops
Chairman and CEO of Alkermes
Alkermes
Episode: Ep200: Richard Pops Reflects on a 35-Year Career in Biotech
Martin Burke
Professor of chemistry; director of the Molecule Maker Lab at University of Illinois
University of Illinois at Urbana-Champaign
Episode: Ep199: Martin Burke on Making Small Molecule Medicines for the AI Era
Abbas Kazimi
CEO Nimbus Therapeutics
Nimbus Therapeutics
Episode: Ep198: Abbas Kazimi on Computation and Culture for Drug Discovery
Viswa Colluru
Founder and CEO, Enveda
Enveda Biosciences
Episode: Ep197: Viswa Colluru on Discovering Drugs Inspired by Mother Nature

Host

Luke Timmerman
Host of The Long Run

Reviews

4.7 out of 5 stars from 179 ratings
  • Staying Up-to-Date with Timmerman

    I have an alert set for each episode drop. As someone who writes for biotech companies, I enjoy listening to each guest detail their company, mission, and plan to continue to improve every facet of healthcare. Luke has amazing interview skills and this is one of my top 3 podcasts!

    Apple Podcasts
    5
    Lauren Esmay
    United States2 years ago
  • Loved the last 2 episodes!

    Discussions around gene regulation with Rick Young and finding your purpose with Robert Ang really stood out to me. Thanks for sharing such great stories.

    Apple Podcasts
    5
    ladyscientistpodcast
    United States2 years ago
  • Insightful + Engaging!

    It’s obvious that Luke puts extraordinary effort in covering salient topics and finding knowledgeable guests that truly care about being a positive force in this world. A must listen for anyone interested in the biotech space!

    Apple Podcasts
    5
    Arlie K
    United States5 years ago
  • A treat while social distancing

    During these unusual times, I have found the human stories behind the long run and the great people in our industry a wonderful treat. I listen while walking the hills of SF and feel connected to our community even when we are apart. Thanks Luke. Keep up the awesome work focused on people.

    Apple Podcasts
    5
    chichi5678
    United States6 years ago
  • Great Podcast

    I am someone that is not in the bio tech world, but find it absolutely fascinating. Luke has a great ability as an interviewer to ask questions that makes complex bio tech topics, understandable and not condescending to people are not immersed in the bio tech world.

    Apple Podcasts
    5
    1-2-3 Josh
    United States6 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Several reviews highlight high production quality concerns affecting listening experience.
Some notes call for the host to let guests speak more and minimize interjections.
Listeners praise deep, interview-driven exploration of biotech with actionable industry insights.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#233
United States/Science
Apple Podcasts
#192
United Kingdom/Science
Apple Podcasts
#36
Ukraine/Science
Apple Podcasts
#90
Singapore/Science
Apple Podcasts
#120
South Korea/Science
Apple Podcasts
#216
Switzerland/Science

Talking Points

Recent interactions between the hosts and their guests.

Ep204: Troy Wilson on Precision Cancer Drugs and Combos
Q: How does Kura approach combination therapies and strategic partnerships in AML?
The discussion emphasizes leveraging Menin inhibitors with Ras pathway inhibitors and FTIs, pursuing frontline and combination strategies, and building a fully integrated company to shepherd drugs from discovery through approval while optimizing patient outcomes.
Ep204: Troy Wilson on Precision Cancer Drugs and Combos
Q: Why did you pivot from pursuing an MD to law and then business to lead biotech ventures?
He explains a preference for applying scientific knowledge in a broader business and legal context, recognizing that entrepreneurial finance, corporate development, and strategic decision-making suited his strengths more than a traditional clinical path.
Ep204: Troy Wilson on Precision Cancer Drugs and Combos
Q: What early experiences shaped your path toward biotech entrepreneurship?
Troy describes a trajectory through physics and chemistry, mentoring in Berkeley and LBL, and pivotal roles at GNF and the Schultz lab that trained him to pursue high-impact, interdisciplinary opportunities, ultimately leading to starting Ambrix and later Avidity and Kura.
Ep201: Jeremy Levin on Biotech in the Balance
Q: What are the first couple of commitments you highlight and why are they important?
The first commitments focus on relentless adherence to scientific truth and data integrity, with a public pledge to transparency and patient-centricity; these are foundational for rebuilding trust and ensuring that regulatory and public opinions align with the realities of science.
Ep200: Richard Pops Reflects on a 35-Year Career in Biotech
Q: When did Alkermes shift from being a royalties-driven company to prioritizing proprietary medicines, and why?
The shift happened as the company matured; after realizing the limitations of relying on royalties from others, they retooled to develop proprietary medicines that could drive meaningful breakthroughs, especially in CNS and sleep biology, enabling greater control over fate and long-term value.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About The Long Run

What is The Long Run about and what kind of topics does it cover?

The show features long-form conversations with biotech leaders, scientists, and investors about drug discovery, company building, and the evolving biotech landscape. Topics frequently center on innovative platforms for small-molecule and biologic therapies, AI-enabled discovery, and the practicalities of bringing science to patients—from early-stage research to regulatory and policy challenges. Episodes often blend origin stories, strategic decision-making, and real-world industry dynamics, offering actionable insights for entrepreneurs, investors, and R&D teams curious about how scientific ideas become impactful medicines. A notable strength is the breadth of high-profile guests spanning academia, startups, and pharma, which yields a rich ... more

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Which podcasts are similar to The Long Run?

These podcasts share a similar audience with The Long Run:

1. BioCentury This Week
2. The Readout Loud
3. Biotech Hangout
4. Biotech 2050 Podcast
5. Business Of Biotech

How many episodes of The Long Run are there?

The Long Run launched 9 years ago and published 204 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Long Run?

Recent guests on The Long Run include:

1. Heather Turner
2. Troy Wilson
3. Sri Kosuri
4. Becky Pferdehirt
5. Jeremy Levin
6. Richard Pops
7. Martin Burke
8. Abbas Kazimi

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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