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BioCentury This Week

BioCentury
FDA
China
Biotech
Biotechnology
Clinical Trials
Biosecure Act
Obesity
Biotech Industry
Mergers and Acquisitions
Drug Development
Alzheimer's Disease
Gene Therapy
FDA Regulations
Novo Nordisk
Inflation Reduction Act
Biotech Innovation
Pediatric Priority Review Vouchers
Biopharma
Grand Rounds
Psychedelics

BioCentury's streaming commentary on biotech industry trends, plus interviews with KOLs.For three decades, BioCentury has helped biopharma executives and investors make business-critical decisions and build larger networks with peers across the innovation ecosystem.

PublishesTwice weeklyEpisodes397Founded6 years ago
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Life SciencesBusinessScience

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Latest Episodes

Note: This episode was briefly published with an incorrect audio file, which has since been corrected.

FDA is prepared to approve psychedelic therapies for chronic psychiatric disorders before sponsors have fully determined how long the effects last... more

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A pair of high profile clinical setbacks has wiped out more than $40 billion in market cap for Novartis, most of which stemmed from the Phase III miss of antisense oligonucleotide therapy pelacarsen. On the latest BioCentury This Week podcast, BioCen... more

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Mid-sized biopharma companies are under growing pressure to accept most-favored nation drug pricing deals with the White House. On the latest BioCentury This Week podcast, BioCentury's analysts assess the trade-offs companies face, the litigation ris... more

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China has changed the global narrative on delivering early human clinical data, with a new bar for speed and efficiency. And now drug developers and policymakers around the world have gotten the message and know that this is no time for complacency. ... more

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Recent Guests

Lindsay Martin
Biopharma analyst
BioCentury
Episode: Ep. 374 - Parkinson's deep dive & FDA trial reforms
Aaron Coe
Managing Director of the Innovation Portfolio at the Allen Institute
Allen Institute
Episode: Ep. 371 - Moving faster at the academia-industry interface
Sam Blackman
Entrepreneur in Residence, previously at Day One Biopharma; biotech executive
GV; Day One Biopharma (past)
Episode: Ep. 371 - Moving faster at the academia-industry interface
Mary Bronco
2025 Nobel Prize winner in Chemistry
Local Seattle area
Episode: Ep. 371 - Moving faster at the academia-industry interface
Matt Hewitt
Representative from Charles River
Charles River
Episode: Ep. 371 - Moving faster at the academia-industry interface
Richard Pops
CEO, Alkermes (former)
Alkermes
Episode: Ep. 369 - ASCO advances, China innovation & U.S. science under threat
Tierney Baum
Bio Pharma Analyst
BioCentury
Episode: Ep. 368 - ASCO Preview, China Policy, ADC Linkers
Richard Pazdur
Director emeritus of the FDA Oncology Center of Excellence, noted regulator discussed in fireside chat
FDA
Episode: Ep. 366 - Europe's need for speed: Bio€quity takeaways
Karen Tkach-Tuzman
Colleague and neighbor, Grand Rounds organizer
BioCentury
Episode: Ep. 364 - UCB’s Candid buy, Grand Rounds and leukodystrophies

Hosts

Stephen Hansen
BioCentury editor and industry observer with UK coverage.
Jeff Cranmer
Host with broad coverage in biotech policy and market dynamics.
Jeff Kranmer
Host focused on market updates and deal analysis.
Simone Fishburne
Editor-in-Chief offering editorial and policy context.

Reviews

4.7 out of 5 stars from 80 ratings
  • terrific summaries capturing the news in this fast-moving space

    LOVE this weekly look at what is happening in biotech, both deep dives into the science itself plus the regulatory/legislative challenges and more. All the regulars are deeply knowledgeable and Jeff Cranmer’s levity as host makes the pod enjoyable and digestible--you really do feel like you have a seat at their editorial meetings. GREAT recaps of the news and in ~30 min or less, I look forward to listening each week!

    Apple Podcasts
    5
    Ios9 problem
    United States2 years ago
  • Great insights and wisdom!

    Awesome helps me and my team navigate efficiently

    Apple Podcasts
    5
    Surfrider182
    United States2 years ago
  • Simone Fishburn!!!!

    Simone Fishburn is so well spoken and such a tremendous host. Need more of her in our lives !!

    Apple Podcasts
    5
    Pretty Kitty 2
    United States6 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Simone Fishburne is repeatedly praised for clear, strong editorial leadership.
Listeners appreciate concise, digestible summaries of fast-moving biotech news.
The host brings levity and clarity, making complex topics approachable.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Ep. 370 - Calmer waters for FDA; Servier, Lilly deals
Q: What exactly did you mean by the real-time clinical trials initiative sweeping away 60 years of tradition?
The host asked for clarification, and the guest explained that while the initiative aims to streamline data handling by focusing on predefined, actionable signals, it is not dismantling the entire regulatory framework; rather it emphasizes improved data plumbing and forward-facing collaboration between sponsors and FDA to prioritize meaningful data while reducing unnecessary data burden.
Ep. 368 - ASCO Preview, China Policy, ADC Linkers
Q: What are the main arguments for and against a more protectionist stance toward China in biotech deals?
Proponents argue that protecting sensitive biotechnologies is essential to national security and long-term leadership, citing high-profile deals as examples; opponents warn that protectionism can curb collaboration, slow innovation, and raise costs, emphasizing that many global science advances require cross-border partnerships.
Ep. 368 - ASCO Preview, China Policy, ADC Linkers
Q: Can you talk a little bit about what the reforms entail, Steve?
The reforms center on embedding clinical trials into routine healthcare delivery, creating a network of trial platforms, with FDA CDER steering coordination, ARPA-H supporting pilots, and NIH driving multiple platform pilots to advance faster, safer, and more efficient early-stage trials.
Ep. 365 - Thin ice for Makary, redosing AAVs
Q: What is the latest on Makary's position and the political dynamics around the FDA leadership?
The hosts discuss reporting that Makary is on thin ice, the role of HHS and the White House in guiding leadership, and the likelihood that an acting commissioner will be appointed with potential internal candidates.
Ep. 362 - AACR: Data and de-risking
Q: Kyle, how are you thinking about ASCO from where you sit at this time of year?
ASCO is a pull-through from AACR and will likely feature more on dual payload ADCs, with early clinical proofs and ongoing discussion of resistance origins. We expect phase one expansion data to be watched, and the data may shape clinical practice discussions while signaling trends for 2027 ASCO.

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Frequently Asked Questions About BioCentury This Week

What is BioCentury This Week about and what kind of topics does it cover?

Biotech-focused analysis and updates, with a steady cadence of market context, policy shifts, and deal-making intersecting with science progress. Episodes frequently dissect FDA timelines, regulatory reforms, and cross-border regulatory dynamics, then pair that with deep dives into therapeutic modalities (ADCs, DACs, CAR-T, gene therapies) and notable clinical readouts from major conferences. Guests range from editors and policy reporters to executives, analysts, and scientists, yielding practical takeaways for sponsors, investors, and operators. A distinctive feature is the blend of rigorous industry data with accessible host commentary and a recurring emphasis on translating science and policy into business strategy. This mix makes it use... more

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1. Biotech Hangout
2. The Readout Loud
3. The BioCentury Show
4. Business Of Biotech
5. The Long Run with Luke Timmerman

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BioCentury This Week launched 6 years ago and published 397 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on BioCentury This Week?

Recent guests on BioCentury This Week include:

1. Lindsay Martin
2. Aaron Coe
3. Sam Blackman
4. Mary Bronco
5. Matt Hewitt
6. Richard Pops
7. Tierney Baum
8. Richard Pazdur

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