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Business Of Biotech

Ben Comer
Clinical Trials
Biotechnology
Drug Development
FDA
Gene Therapy
Biotech
Oncology
Pharmaceutical Industry
Covid-19
Cell and Gene Therapy
Psychedelics
Biopharma
Artificial Intelligence
Biologics
Radiopharmaceuticals
Mrna
Bit.bio
XOMA Royalty
Biopharmaceuticals
Cancer Treatment

The Business of Biotech is the pod dedicated to leaders of emerging biopharma firms. SUBSCRIBE to our new newsletter at www.bioprocessonline.com/bob. We bring you insight into organizational, finance and funding, HR, clinical, manufacturing, regulatory, and commercial challenges you’ll face as you navigate your company from an idea to success in the clinic and beyond. Each episode features guest c... more

PublishesWeeklyEpisodes308Founded6 years ago
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ManagementScienceBusinessLife Sciences

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Latest Episodes

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On this week's episode of the Business of Biotech, Neil McFarlane, CEO at Zevra Therapeutics, talks about transitioning to a focused rare disease company through acquisitions, and building out ... more

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On this week's episode of the Business of Biotech, Marinna Madrid, Ph.D., Cofounder, Board Member, Chief Product and Regulatory Officer at Cellino, talks about scaling up an automated manufactu... more

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On this week's episode of the Business of Biotech, Wyatt McDonnell, Ph.D., cofounder and CEO at Infinimmune, talks about how single-cell biology and computational rigor led to the formation of ... more

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On this week's episode of the Business of Biotech, Brett Monia, Ph.D., CEO at Ionis Pharmaceuticals, talks about how antisense oligonucleotides (ASO) graduated from a late-1980s lab concept to ... more

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Recent Guests

Marinna Madrid
Co-founder, board member, Chief Product and Regulatory Officer at Cellino
Cellino
Episode: Scaling Manufacturing For Personalized Cell Therapies With Cellino's Marinna Madrid, Ph.D.
Wyatt McDonnell
Co-Founder and CEO, Infinimmune
Infinimmune
Episode: Building A New Antibody Discovery Platform With Infinimmune's Wyatt McDonnell, Ph.D.
Brett Monia
CEO and board member at Ionis Pharmaceuticals
Ionis Pharmaceuticals
Episode: From Partnered ASO Therapies To A Wholly-Owned Pipeline With Ionis's Brett Monia, Ph.D.
Adam Rogers
Chairman, President and CEO, NervGen
NervGen
Episode: Implementing A New CEO Strategy With NervGen's Adam Rogers, M.D. And Rich Macary
Rich Macary
Board Advisor, Business Development and Strategy, NervGen
NervGen
Episode: Implementing A New CEO Strategy With NervGen's Adam Rogers, M.D. And Rich Macary
Sarfaraz Niazi
CEO at RNA Therapeutics, CTO and co-founder at Abiolo, CEO at Day Therapeutics
RNA Therapeutics / Abiolo / Day Therapeutics
Episode: Biosimilars And Complex Medicines For All With RNA Therapeutics' Sarfaraz Niazi, Ph.D.
Thijs Spoor
CEO of Perspective Therapeutics
Perspective Therapeutics
Episode: Radiotherapeutics For Neuroendocrine Tumors With Perspective Therapeutics' Thijs Spoor
Dan McHugh
Head of the investment team at Yosemite
Yosemite
Episode: Investing In Early-Stage Oncology With Yosemite's Dan McHugh
Alan Bash
President of Carvykti at Legend Biotech
Legend Biotech
Episode: Commercializing CAR T Cell Therapy With Legend Biotech's Alan Bash

Host

Ben Comer
Host of The Business Of Biotech, Life Science Leader

Reviews

4.6 out of 5 stars from 170 ratings
  • great interview with bit.bio

    Enjoyed your latest episode with bit.bio’s Mark Kotter!

    Apple Podcasts
    5
    ladyscientistpodcast
    United States2 years ago
  • Timely news & interesting guests

    A great way to stay up to date with all that is happening in the biotech world. Lively discussions as the host Matt has unfiltered chats with top industry icons. Best podcast I’ve found in this field!

    Apple Podcasts
    5
    Boddiingsytikgd
    United States2 years ago
  • Great Show!

    Very insightful! Matt's a great host, he knows what questions to ask his guests. A great podcast for latest trends in Biotech and Pharmacy industry!

    Apple Podcasts
    5
    Retchelle_Platforce
    Philippines3 years ago
  • Episodes are great, Newsletter no no no

    I learn so much every episode. The recent episode featuring Recursion was especially helpful.

    The only annoying thing, I signed up for the newsletter after all the talk about it not being “another newsletter” but it’s actually worse than most. WAY too many headlines, poor formatting makes it hard to follow or focus on any particular one, the thing is poorly designed and packed with jargon.

    Apple Podcasts
    5
    Glleee
    United States3 years ago
  • A+ episodes, every time!

    What better way to keep up with the latest in the world of biotech than to hear directly from leaders and innovators shaping the landscape? Engaging conversations, knowledgeable guests, and insights into the industry abound. Don't miss it!

    Apple Podcasts
    5
    Arlie K
    United States4 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Host keeps conversations focused and fast-paced, with data points and takeaways for listeners.
Industry-leading guest list; NPR-level rigor in discussions about biotech challenges.
Engaging conversations with top industry icons and actionable insights for biotech leaders.
Listeners appreciate the breadth of topics from manufacturing to policy.
Great guests and clear questions—valuable for anyone in biopharma.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Scaling Manufacturing For Personalized Cell Therapies With Cellino's Marinna Madrid, Ph.D.
Q: Why are induced pluripotent stem cells so challenging to manufacture at scale?
iPSCs are highly sensitive, require lengthy reprogramming, and rely on expert human judgment; scalability hinges on automating manual steps with AI image analysis and laser-assisted cell manipulation to replace artisanal processes.
From Partnered ASO Therapies To A Wholly-Owned Pipeline With Ionis's Brett Monia, Ph.D.
Q: What's unique about ASO therapies and what challenges do they present?
ASO therapies offer a way to target RNA directly, which can shift drug discovery away from proteins and toward message RNA, but early on the big questions were whether ASOs could enter cells, how they would behave in the body, and whether safety and manufacturing could be scalable.
Radiotherapeutics For CNS Cancers With Plus Therapeutics' Marc Hedrick, M.D.
Q: I'm curious where glioblastoma stands as the lead indication versus pediatric brain cancer, and what that means for regulatory pathways.
Marc explains that lead designation is defined by which indication is likely to be approved first; leptomeningeal cancer currently appears as the more likely near-term approval, with glioblastoma closely following, and both indications showing promising data in Phase 1/2.
Developing Novel Cancer Drugs On A Budget With Iterion Therapeutics' Rahul Aras, Ph.D.
Q: Tagivivint is your lead candidate. Would you mind giving us an overview of its clinical status and strategy going forward?
Tagivivint is a downstream Wnt-beta-catenin inhibitor targeting TIMBL-1. The drug has shown monotherapy activity in hepatocellular carcinoma and is now being explored in combination settings and later-line indications, with plans for a phase 2 study in HCC and potential expansion into colorectal cancer and other Wnt-activated tumors.
An Anthropological Lens On Leadership In Life Sciences With Bunka's Monika Sumra, Ph.D.
Q: What advice would you give to leaders forming a company around exciting technology?
Design the environment for purpose and ensure it supports meaningful human engagement and behavior.

Audience Metrics

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Frequently Asked Questions About Business Of Biotech

What is Business Of Biotech about and what kind of topics does it cover?

The show centers on leaders shaping emerging biopharma firms, with in-depth conversations about scaling biology-centric startups through manufacturing, regulatory navigation, financing, and go-to-market strategies. Episodes frequently explore topics like autologous and allogeneic cell therapy, antibody platforms, radiopharmaceuticals, biosimilars, and early-stage biotech investing, often featuring founders, CEOs, CROs, CFOs, and board members sharing practical lessons from building companies, securing partnerships, and advancing therapies toward patients. A notable strength is bringing senior industry figures who combine scientific prowess with business execution, giving listeners clear takeaways on leadership, risk management, and strategi... more

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Which podcasts are similar to Business Of Biotech?

These podcasts share a similar audience with Business Of Biotech:

1. Biotech Hangout
2. BioCentury This Week
3. The Long Run with Luke Timmerman
4. The Readout Loud
5. Biotech 2050 Podcast

How many episodes of Business Of Biotech are there?

Business Of Biotech launched 6 years ago and published 308 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact Business Of Biotech?

Our systems regularly scour the web to find email addresses and social media links for this podcast. We scanned the web and collated all of the contact information that we could find in our podcast database. But in the unlikely event that you can't find what you're looking for, our concierge service lets you request our research team to source better contacts for you.

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What guests have appeared on Business Of Biotech?

Recent guests on Business Of Biotech include:

1. Marinna Madrid
2. Wyatt McDonnell
3. Brett Monia
4. Adam Rogers
5. Rich Macary
6. Sarfaraz Niazi
7. Thijs Spoor
8. Dan McHugh

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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