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Business Of Biotech

Ben Comer
Clinical Trials
Biotechnology
Drug Development
FDA
Gene Therapy
Biotech
Oncology
Pharmaceutical Industry
Covid-19
Cell and Gene Therapy
Psychedelics
Biopharma
Artificial Intelligence
Biologics
Radiopharmaceuticals
Mrna
Bit.bio
XOMA Royalty
Biopharmaceuticals
Obesity

The Business of Biotech is the pod dedicated to leaders of emerging biopharma firms. SUBSCRIBE to our new newsletter at www.bioprocessonline.com/bob. We bring you insight into organizational, finance and funding, HR, clinical, manufacturing, regulatory, and commercial challenges you’ll face as you navigate your company from an idea to success in the clinic and beyond. Each episode features guest c... more

PublishesWeeklyEpisodes327Founded6 years ago
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ManagementBusinessLife SciencesScience

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Latest Episodes

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On this week's episode of the Business of Biotech, Cyriac Roeding talks about cofounding and leading Earli, a "bioAI" company using synthetic DNA switches and cancer-binding lipid nanoparticles... more

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On this week's episode of the Business of Biotech, Philina Lee, Ph.D., CEO at AdvanCell, explains how lead-based targeted alpha therapies can unlock deeper, more durable cancer responses, and w... more

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On this week's episode of the Business of Biotech, Alex Aravanis, M.D., Ph.D., CEO of Moonwalk Biosciences, talks about the opportunity in obesity beyond GLP-1s. He describes Moonwalk’s adipose... more

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On this week's episode of the Business of Biotech, Independent Board Director and five-time public company CFO Alan Shaw returns to the show for an update on current biotech financing and the s... more

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Recent Guests

Alex Aravanis
CEO of Moonwalk Biosciences
Moonwalk Biosciences
Episode: Finding New Opportunities In Obesity With Moonwalk Bioscience's Alex Aravanis, M.D., Ph.D.
David Craig
Co-Founder, President and CEO at Sarcomatrix
Sarcomatrix
Episode: Funding A Virtual Biotech Without Institutional Capital With Sarcomatrix's David Craig
Matt Winton
Chief Commercial and Business Officer at CervoMed
CervoMed
Episode: Late-Stage Development And Commercial Planning With CervoMed's Matt Winton, Ph.D.
Al Sandrock
President and CEO at Voyager Therapeutics
Voyager Therapeutics
Episode: Targeting Tau in Alzheimer's Disease With Voyager Therapeutics' Al Sandrock, M.D., Ph.D.
William Ho
Co-founder and CEO at IN8bio (formerly Incisis Therapeutics)
IN8bio
Episode: Keeping An Early-Stage Cell Therapy Biotech In The Black With IN8bio's William Ho
William Soliman
Founder and CEO, Accreditation Council for Medical Affairs (ACMA); Founder and CIO, White Manna Capital Partners
ACMA, White Manna Capital Partners
Episode: Drug Launch Success In A Changing Commercial Landscape With ACMA's William Soliman, Ph.D.
Jeff Jonas
CEO of Tortugas Neuroscience
Tortugas Neuroscience
Episode: Derisking CNS Drug Development With Tortugas Neuroscience's Jeff Jonas, M.D.
Neil McFarlane
President, CEO and Board Director at Zevra Therapeutics
Zevra Therapeutics
Episode: Rare Disease Drug Commercialization With Zevra Therapeutics' Neil McFarlane
Marinna Madrid
Co-founder, board member, Chief Product and Regulatory Officer at Cellino
Cellino
Episode: Scaling Manufacturing For Personalized Cell Therapies With Cellino's Marinna Madrid, Ph.D.

Host

Ben Comer
Host of The Business Of Biotech

Reviews

4.6 out of 5 stars from 174 ratings
  • great interview with bit.bio

    Enjoyed your latest episode with bit.bio’s Mark Kotter!

    Apple Podcasts
    5
    ladyscientistpodcast
    United States3 years ago
  • Timely news & interesting guests

    A great way to stay up to date with all that is happening in the biotech world. Lively discussions as the host Matt has unfiltered chats with top industry icons. Best podcast I’ve found in this field!

    Apple Podcasts
    5
    Boddiingsytikgd
    United States3 years ago
  • Great Show!

    Very insightful! Matt's a great host, he knows what questions to ask his guests. A great podcast for latest trends in Biotech and Pharmacy industry!

    Apple Podcasts
    5
    Retchelle_Platforce
    Philippines4 years ago
  • Episodes are great, Newsletter no no no

    I learn so much every episode. The recent episode featuring Recursion was especially helpful.

    The only annoying thing, I signed up for the newsletter after all the talk about it not being “another newsletter” but it’s actually worse than most. WAY too many headlines, poor formatting makes it hard to follow or focus on any particular one, the thing is poorly designed and packed with jargon.

    Apple Podcasts
    5
    Glleee
    United States4 years ago
  • A+ episodes, every time!

    What better way to keep up with the latest in the world of biotech than to hear directly from leaders and innovators shaping the landscape? Engaging conversations, knowledgeable guests, and insights into the industry abound. Don't miss it!

    Apple Podcasts
    5
    Arlie K
    United States4 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Engaging format with a pragmatic biotech lens.
Host keeps conversations focused and actionable.
Strong coverage of industry trends and company-building.
Newsletter critique is noted by some listeners.
High-quality guests and insights into biotech leadership.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Biotech Finance And Investor Update With Independent Board Director Allan Shaw
Q: When considering capital strategy, how should management weigh dilutive vs non-dilutive funding and strategic partnerships?
Runway management is crucial; treat runway as a negotiating asset and use partnerships to de-risk and unlock value without sacrificing long-term control. Non-dilutive funding can help, but it may come with trade-offs in economics; strategic partnerships can provide capital affinity, manufacturing, and commercial capabilities that offset dilution while advancing milestones.
Biotech Finance And Investor Update With Independent Board Director Allan Shaw
Q: What is the role of differentiation and how should a company demonstrate it to investors?
Differentiation can be through modality, indication, biomarker-defined populations, or first-in-class/best-in-class profiles; it also includes patient enrichment, dosing convenience, and strategic validation. The goal is to show a credible path to market with reduced risk and clear competitive advantage.
Funding A Virtual Biotech Without Institutional Capital With Sarcomatrix's David Craig
Q: What is your day-to-day like running a virtual biotech, and what can't be outsourced?
The core leadership, quality systems, and regulatory interface should stay in-house; most operational work is outsourced to vetted partners, with a small, closely managed internal team and fractional senior roles as needed.
Funding A Virtual Biotech Without Institutional Capital With Sarcomatrix's David Craig
Q: What are the key advantages and drawbacks of non-institutional financing compared with traditional VC funding?
Non-institutional financing offers flexibility and faster access to capital in some cases but requires more complex governance, rigorous compliance, and active marketing; it also demands a diversified strategy across pre-seed, seed, Series A, and B to avoid blocking future rounds.
Funding A Virtual Biotech Without Institutional Capital With Sarcomatrix's David Craig
Q: Do you think it's harder today to start a biotech and fund a program compared to the early Amgen days?
Yes, it's significantly harder; you have to be creative, leverage grants, crowdfunding, and strategic partnerships, and run a lean operation with high-quality in-house regulatory oversight while outsourcing non-core functions.

Audience Metrics

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Frequently Asked Questions About Business Of Biotech

What is Business Of Biotech about and what kind of topics does it cover?

The show centers on leaders and emerging companies in biopharma, with in-depth conversations about science, strategy, and execution across drug discovery, manufacturing, regulatory, and commercialization. Episodes regularly explore complex topics such as Tau-targeted approaches in neurodegeneration, cell therapy manufacturing at scale, rare disease commercialization, CNS and neurotrauma programs, and the evolving funding and regulatory landscape. A notable strength is the host's ability to balance technical nuance with practical lessons for founders and executives, often drawing on firsthand experiences from CEOs, CFOs, and senior leaders. Listeners can expect actionable insights on building startups, navigating funding cycles, forming part... more

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Which podcasts are similar to Business Of Biotech?

These podcasts share a similar audience with Business Of Biotech:

1. Biotech Hangout
2. BioCentury This Week
3. The Long Run with Luke Timmerman
4. The Readout Loud
5. Biotech 2050 Podcast

How many episodes of Business Of Biotech are there?

Business Of Biotech launched 6 years ago and published 327 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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Our systems regularly scour the web to find email addresses and social media links for this podcast. We scanned the web and collated all of the contact information that we could find in our podcast database. But in the unlikely event that you can't find what you're looking for, our concierge service lets you request our research team to source better contacts for you.

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What guests have appeared on Business Of Biotech?

Recent guests on Business Of Biotech include:

1. Alex Aravanis
2. David Craig
3. Matt Winton
4. Al Sandrock
5. William Ho
6. William Soliman
7. Jeff Jonas
8. Neil McFarlane

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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