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CRISPR
Gene Therapy
Human Genome Project
Artificial Intelligence
Gene Editing
Nanoparticles
DNA
Eli Lilly
AI In Drug Discovery
Mrna Therapeutics
Rosalind Franklin
Biotechnology
FDA
NVIDIA
Drug Discovery
Autism
Genealogy
AACR
Moderna
Genetic Engineering

Touching Base is the dynamic podcast series from the editors of GEN (Genetic Engineering & Biotechnology News). Each episode features a rotating cast of senior editors including John Sterling, Kevin Davies, Julianna LeMieux, Alex Philippidis, Uduak Thomas, Corinna Singleman and Fay Lin who delve into emerging stories, exchange ideas, and debate the latest trends in biotech. Additionally, they talk... more

PublishesTwice monthlyEpisodes48Founded2 years ago
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NewsLife SciencesNews CommentaryScience

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Artwork for Touching Base

Latest Episodes

Some GEN editors were in sunny San Diego covering the hottest research, trends, and products from the American Association for Cancer Research meeting. We kick things off with news from America’s Finest City, particularly around the growing role of A... more

From designing drugs with a simple text prompt to running experiments guided by extended reality, a new wave of agentic AI is transforming the modern lab. Our editors discuss the latest autonomous systems accelerating biological discovery. In busines... more

This week, agentic AI steps into the limelight buoyed by the momentum from generative AI. And there’s a new virtual cell model in town courtesy of AI-drug developer Xaira Therapeutics. From the frontiers of AI, our discussion turned to feats of engin... more

A new study from the J. Craig Venter Institute simulates the complete life cycle of a minimal bacterial cell in 4D space and time at nanoscale resolution. Meanwhile, in gene editing, a new technology has designed DNA donors that evade the immune syst... more

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Recent Guests

Mark Tesse-Lavigne
CEO, Xaira
Xaira
Episode: Agentic AI, Virtual Cell, LNP Vaccine Boosters, Engineered Organs, and Mergers
Bo Wang
Senior Vice President and Head of Biomedical AI
Xaira
Episode: Agentic AI, Virtual Cell, LNP Vaccine Boosters, Engineered Organs, and Mergers
Michelle Lee
CEO of Medra
Medra
Episode: Women in Science, Robotics, Automation, SLAS, and Lilly Updates
Scott Ripley
Vice President and General Manager of Nucleic Acids and Nanomedicines at Cytiva
Cytiva
Episode: Navigating Biotech’s New Normal, Applying AI to Cas9 Enzymes, and Sequencing Generations
Francis Collins
Former Director of the NIH
National Institutes of Health
Episode: Genetic Engineering at Asilomar, Stand Up for Science, and Francis Collins

Host

Corinna Singleman
Managing Editor of GEN; Host and editor coordinating coverage and interviews.

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Agentic AI, Virtual Cell, LNP Vaccine Boosters, Engineered Organs, and Mergers
Q: What are the practical implications of agentic AI for life sciences and pharma pipelines?
Agentic AI offerings, when designed with strong safety controls and federated data approaches, can accelerate hypothesis generation, model-driven design, and collaborative drug discovery while allowing companies to share data without compromising proprietary information.
uniQure Staggers at FDA, Recursion's Microglia Map, and Leadership Transitions
Q: Were there any really great takeaways from the summit for future looking?
The summit emphasized the need for more proof points in AI drug discovery to balance hype with reality.
uniQure Staggers at FDA, Recursion's Microglia Map, and Leadership Transitions
Q: What could impact Unicure's efforts here with FDA leadership changes?
The ongoing leadership instability at the FDA could impact Unicure's interactions and regulatory outcomes.
Sarepta Under Scrutiny, AstraZeneca’s Big Bet, and AI vs. IDRs
Q: Does that $50 billion, with a B, which is crazy to me, in dollar investment, is that just for the Virginia location or is that for all of these improvements?
The $50 billion is across all of AstraZeneca's projects, not just the Virginia location.
Sarepta Under Scrutiny, AstraZeneca’s Big Bet, and AI vs. IDRs
Q: Is there any indication that you've heard of at all that patients are worried about just stopping the treatment?
Concerns exist broadly in the patient community regarding the FDA's demands to halt shipments and the implications for patient safety.

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Frequently Asked Questions About Touching Base

What is Touching Base about and what kind of topics does it cover?

The show centers on biotech industry news, trends, and policy, with a focus on AI in life sciences, gene therapy, regenerative medicine, and biopharma deals. Hosts and editors dissect major developments from research breakthroughs to regulatory shifts, often featuring practical implications for researchers, companies, and investors. A consistent throughline is the intersection of cutting-edge biology with technology (notably AI) and the business dynamics shaping biotech, including mergers, partnerships, and funding. Noteworthy is the panel-led format that blends reporter perspectives with industry context, plus frequent coverage of real-world applications and translational hurdles. Potential listeners include professionals in biotech, pharm... more

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Which podcasts are similar to Touching Base?

These podcasts share a similar audience with Touching Base:

1. Behind the Breakthroughs
2. The Readout Loud
3. Drug Story
4. BioCentury This Week
5. Biotech Hangout

How many episodes of Touching Base are there?

Touching Base launched 2 years ago and published 48 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Touching Base?

Recent guests on Touching Base include:

1. Mark Tesse-Lavigne
2. Bo Wang
3. Michelle Lee
4. Scott Ripley
5. Francis Collins

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