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Sean Hashmi, MD

Sean Hashmi, MD
Chronic Kidney Disease
Kidney Disease
Iga Nephropathy
Kidney Health
Weight Loss
Diabetes
Diabetic Kidney Disease
SGLT2 Inhibitors
Kidney Function
Pig Kidney Transplantation
Polycystic Kidney Disease
ACE Inhibitors
Heavy Metals
Xenotransplantation
Protein Powders
Kidney Failure
Proteinuria
Nutrition
Cadmium
Lead

Welcome to the SELF Principle Podcast with Dr. Sean Hashmi—a board-certified nephrologist and obesity medicine specialist helping you live longer through evidence-based medicine. SELF stands for Sleep, Exercise, Love, and Food—the four pillars of lasting health. Each episode breaks down complex medical research into practical strategies for metabolic health, kidney protection, and longevity. No fa... more

PublishesTwice weeklyEpisodes67Founded8 months ago
Number of ListenersCategory
Health & Fitness

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Artwork for Sean Hashmi, MD

Latest Episodes

Your creatinine is high, and here is what actually lowers it. Your social media feed is full of teas and morning drinks promising to flush it down. Most do nothing, and some can actually harm your kidneys.

In this episode, Dr. Sean Hashmi explains w... more

Creatine isn't just for muscle. A video with millions of views says it shrinks your fat cells by 30%. The evidence does not show that, and the real story runs past muscle into your brain and into your kidney lab results.

In this episode, Dr. Sean Ha... more

Are your blood pressure pills hurting your kidneys? Your social media feed keeps saying so. For most people, the truth runs the other way: the right medications are the strongest kidney protection we have.

In this episode, Dr. Sean Hashmi explains w... more

You can be thin, eat clean, hit your steps, and still have the kind of belly fat that destroys your kidneys.

A 2023 PLOS One cohort followed 11,050 adults for nearly 6 years. The highest visceral fat group had 7.5 times the risk of chronic kidney di... more

The 10-second balance test that predicts how long you'll live. If you can't stand on one leg for 10 seconds, one 2022 study found your risk of dying over the next several years was about 1.84 times higher, an 84% jump.

That number comes from a 2022 ... more

You can be thin, eat clean, hit your steps, and still have the kind of belly fat that destroys your kidneys.

A 2023 PLOS One cohort followed 11,050 adults for nearly 6 years. The highest visceral fat group had 7.5 times the risk of chronic kidney di... more

Your creatinine test may be lying to you. The 2021 National Kidney Foundation guidance recommends cystatin C as a second kidney test. Four years later, most labs still default to creatinine alone.

By the time creatinine clearly rises on a lab report... more

A new triple-agonist shot, retatrutide, just posted the biggest weight loss we have ever seen from a single injection in a phase 3 obesity trial: 28.3% of body weight at 80 weeks, roughly 70 pounds, and almost double what Ozempic delivered in its piv... more

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Dr. Sean Hashmi
Board-certified nephrologist and obesity medicine specialist; host and medical expert guiding evidence-based discussions on kidney health, metabolic health, and longevity.

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Talking Points

Recent interactions between the hosts and their guests.

Psychology beats willpower: The 20% weight loss maintenance secret
Q: How do I get started with changing my eating habits?
Start with one tiny habit tied to existing routines, track it for sixty-six days.
Psychology beats willpower: The 20% weight loss maintenance secret
Q: What is your why for weight loss?
It should be based on internal values rather than just wanting to look better.
Kidney Test Lying to You? 2025 Breakthrough Revealed
Q: What about doing intermittent fasting instead of keto?
Intermittent fasting allows cells to repair through autophagy, while ketogenic diets reduce inflammation and provide ketones as fuel.
Kidney Test Lying to You? 2025 Breakthrough Revealed
Q: Are GLP-1s safe if I have chronic kidney disease stage 3?
Yes, semaglutide has shown kidney and heart benefits in that population, but monitoring is essential.
Kidney Test Lying to You? 2025 Breakthrough Revealed
Q: Should I get cystatin C tested if my creatinine is normal?
Cystatin C could tell you kidney damage years before creatinine does, especially if you are over 60, have diabetes, high blood pressure, or low muscle mass.

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Frequently Asked Questions About Sean Hashmi, MD

What is Sean Hashmi, MD about and what kind of topics does it cover?

The show centers on evidence-based kidney health, metabolic health, and longevity, translating complex medical research into practical, actionable strategies. Across episodes, topics commonly explore kidney function, obesity, diabetes risk, and dietary or lifestyle interventions, with frequent deep-dives into insulin dynamics, blood sugar regulation, and emerging therapies in nephrology. A distinctive element is the SELF Principle framework—Sleep, Exercise, Love, and Food—which guides actionable steps for better health, and a willingness to discuss cutting-edge developments like xenotransplantation, GLP-1 therapies, and novel kidney disease treatments in accessible terms. The host's medical background and emphasis on data-driven approaches ... more

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1. The Megyn Kelly Show

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Sean Hashmi, MD launched 8 months ago and published 67 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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