
Welcome to the SELF Principle Podcast with Dr. Sean Hashmi—a board-certified nephrologist and obesity medicine specialist helping you live longer through evidence-based medicine. SELF stands for Sleep, Exercise, Love, and Food—the four pillars of lasting health. Each episode breaks down complex medical research into practical strategies for metabolic health, kidney protection, and longevity. No fa... more
| Publishes | Twice weekly | Episodes | 67 | Founded | 8 months ago |
|---|---|---|---|---|---|
| Number of Listeners | Category | Health & Fitness | |||

Your creatinine is high, and here is what actually lowers it. Your social media feed is full of teas and morning drinks promising to flush it down. Most do nothing, and some can actually harm your kidneys.
In this episode, Dr. Sean Hashmi explains w... more
Creatine isn't just for muscle. A video with millions of views says it shrinks your fat cells by 30%. The evidence does not show that, and the real story runs past muscle into your brain and into your kidney lab results.
In this episode, Dr. Sean Ha... more
Are your blood pressure pills hurting your kidneys? Your social media feed keeps saying so. For most people, the truth runs the other way: the right medications are the strongest kidney protection we have.
In this episode, Dr. Sean Hashmi explains w... more
You can be thin, eat clean, hit your steps, and still have the kind of belly fat that destroys your kidneys.
A 2023 PLOS One cohort followed 11,050 adults for nearly 6 years. The highest visceral fat group had 7.5 times the risk of chronic kidney di... more
The 10-second balance test that predicts how long you'll live. If you can't stand on one leg for 10 seconds, one 2022 study found your risk of dying over the next several years was about 1.84 times higher, an 84% jump.
That number comes from a 2022 ... more
You can be thin, eat clean, hit your steps, and still have the kind of belly fat that destroys your kidneys.
A 2023 PLOS One cohort followed 11,050 adults for nearly 6 years. The highest visceral fat group had 7.5 times the risk of chronic kidney di... more
Your creatinine test may be lying to you. The 2021 National Kidney Foundation guidance recommends cystatin C as a second kidney test. Four years later, most labs still default to creatinine alone.
By the time creatinine clearly rises on a lab report... more
A new triple-agonist shot, retatrutide, just posted the biggest weight loss we have ever seen from a single injection in a phase 3 obesity trial: 28.3% of body weight at 80 weeks, roughly 70 pounds, and almost double what Ozempic delivered in its piv... more









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The show centers on evidence-based kidney health, metabolic health, and longevity, translating complex medical research into practical, actionable strategies. Across episodes, topics commonly explore kidney function, obesity, diabetes risk, and dietary or lifestyle interventions, with frequent deep-dives into insulin dynamics, blood sugar regulation, and emerging therapies in nephrology. A distinctive element is the SELF Principle framework—Sleep, Exercise, Love, and Food—which guides actionable steps for better health, and a willingness to discuss cutting-edge developments like xenotransplantation, GLP-1 therapies, and novel kidney disease treatments in accessible terms. The host's medical background and emphasis on data-driven approaches ... more
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Sean Hashmi, MD launched 8 months ago and published 67 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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