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The Startup Different Podcast

David and Chris Sinkinson
Artificial Intelligence
Amazon
Openai
Anthropic
Chatgpt
Manshowr
Quantum Computing
AI Agents
Pureprep
Meal Planning
Holiday Season
Artificial General Intelligence
Elon Musk
Startup Hiring
Entrepreneurship
Initial Public Offerings
Vacations
Burnout
Social Media Advertising
Jasper

SIGNAL AWARDS 2025 - BEST INDIE PODCAST - SILVER COMMUNICATOR AWARDS 2025 - BUSINESS - EXCELLENCE DAVEY AWARDS 2025 - PODCAST SERIES TALK SHOW - SILVER Startup Different is what happens when two brothers who’ve built and sold startups start debating whether AI is taking over — or just overhyped. Brothers and entrepreneurs Dave and Chris bring humor, hard-earned experience, and a touch of chaos to ... more

PublishesWeeklyEpisodes131Founded3 years ago
Category
Business

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Latest Episodes

Tech billionaires like Bryan Johnson are spending millions trying to hack death — blood plasma transfusions, stem cell injections, hundreds of supplements daily.

But legendary Silicon Valley journalist Kara Swisher just launched a CNN docuseries ar... more

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Google News started showing Polymarket gambling bets right alongside articles from Reuters, The Guardian, and the Financial Times — and when people noticed, Google called it "an error." But was it really?

With Google already having a formal data pa... more

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Anthropic just announced something that should make every founder sit up and pay attention: their new AI model, Claude Mythos, can autonomously find and exploit zero-day vulnerabilities in every major operating system and every major web browser.

W... more

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Chris has a confession to make. While co-hosting a podcast about building startups, he's been quietly building one of his own - and today he's pulling back the curtain.

PurePrep is a premium meal planning and recipe management app built for familie... more

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In this episode, Dave reveals his latest venture, ManShowr, a innovative product designed for quick, effective personal cleaning on the go.

He shares the journey from concept to manufacturing, marketing strategies, and the challenges of launching a... more

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Starting June 2026, if your startup uses AI-generated people in advertising and doesn't label them, you could face thousands of dollars in fines.

New York's new synthetic performer disclosure law - the first of its kind in the U.S. - requires adver... more

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AI coding tools have made individual developers dramatically faster - so why aren't teams shipping dramatically faster products? This week, Agoda Engineering published a fascinating analysis of what they're calling "The Velocity Paradox," and it reve... more

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In what reads like the plot of a tech thriller, Anthropic just revealed that three Chinese AI labs - DeepSeek, Moonshot AI, and MiniMax - created over 24,000 fake accounts and generated 16 million exchanges with their Claude model in an industrial-sc... more

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Recent Guests

Christopher Singleton
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Hosts

Dave
Host on the show, frequently leading discussions about startups, product strategy, and AI-driven disruption; appears across many episodes with emphasis on practical experience.
Chris
Co-host of the show, participates in startup-focused debates and analysis, with a penchant for humorous banter and critical perspectives on tech hype.

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Frequently Asked Questions About The Startup Different Podcast

What is The Startup Different Podcast about and what kind of topics does it cover?

Two brothers who've built and sold startups critique how AI, tech, and business models reshape startups, work, and markets. Across recent episodes they bounce between practical product and growth tactics, AI regulation and governance, platform dynamics, hiring in the age of automation, and the economics of content, data, and partnerships. The cadence is informal and humorous, but grounded in hard-earned experience, with frequent debates about strategy, risk, and the human side of rapid technological change. Listeners can expect candid takes on go-to-market moves, product-market fit, and how to navigate a world where AI tools and platform economies redefine competitive advantage. A notable strength is the mix of hands-on startup pragmatism a... more

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1. Morning Brew Daily
2. All-In with Chamath, Jason, Sacks & Friedberg

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The Startup Different Podcast launched 3 years ago and published 131 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Startup Different Podcast?

Recent guests on The Startup Different Podcast include:

1. Christopher Singleton

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