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The Call by the Global Intelligence Desk

The U.S. Chamber of Commerce Global Intelligence Desk
China
Iran
United States
Ukraine
Panama Canal
Sanctions
Strait Of Hormuz
Russia
United States Dollar
Mythos
Venezuela
United States Treasury
Oil
Inflation
NATO
Moon
Iranian Nuclear Program
Tehran
Cybersecurity
Industrial Policy

Hosted by Jay Sapsford, The Call delivers timely and incisive analysis to help businesses navigate risks and opportunities.

PublishesWeeklyEpisodes79Foundeda year ago
Number of ListenersCategory
Business

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Artwork for The Call by the Global Intelligence Desk

Latest Episodes

In April, Ukrainian President Volodymyr Zelenskyy announced his forces captured Russian positions using only ground robots and drones. No infantry. No losses. Kyiv’s success, however, disguises the role of human capital behind the machinery deployed ... more

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The world is aging. For our lifetimes, that has meant low interest rates, as limited demand, high savings and a flexible global workforce created favorable conditions for easy money. Our guest today, Manoj Pradhan, founder of Talking Heads Macro, arg... more

The rivalry between Washington and Beijing has entered a less predictable phase. Tariffs are no longer simply bargaining tools but structural features of the relationship. Export controls and investment restrictions are accelerating a technological s... more

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Washington and Beijing are engaged in a far-reaching rivalry, spanning trade, capital, development finance, and supply chains—ultimately shaping the global economy. For countries and companies alike, the task is increasingly to navigate between these... more

The U.S. Treasury has announced that it will release what it describes as the “financial equivalent,” of a military campaign on Iran, threatening to cut off any bank, company, or country that continues doing business with the U.S. adversary. Warning ... more

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A new age of cybersecurity threats has arrived.

Two weeks ago, the world learned about an unprecedented new AI capability that will change the cyber landscape. Anthropic developed Mythos, a powerful corporate security tool specially designed for cod... more

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Talks in Islamabad have collapsed. A U.S. naval blockade of Iranian ports is now underway. The Strait of Hormuz, through which passes roughly a fifth of the world's seaborne energy, remains effectively closed, triggering what some have called the lar... more

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Immediately after Russia invaded Ukraine in 2022, the U.S. and its allies froze roughly $300 billion in Russian central bank reserves. The move shocked the world, signaling that assets – dollar assets – can be seized, setting a frightening precedent ... more

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Recent Guests

Eliot Cohen
Former State Department Counselor under Condoleezza Rice; Arleigh Burke Chair of Strategy at CSIS
CSIS
Episode: Will the Future of Warfare Still Depend on Humans?
Manoj Pradhan
Founder of Talking Heads Macro
Talking Heads Macro
Episode: Are We Ready for an Era of Higher Interest Rates?
Jeremie Waterman
President of the China Center
U.S. Chamber of Commerce
Episode: Can the U.S. counter China’s state-driven economy?
Juan Zarate
Former Deputy National Security Advisor; Global Co-Managing Partner at K2 Integrity
K2 Integrity
Episode: Should the U.S. Treasury Be an Agency of National Security?
Bill Jewell
Chief Technology Officer
U.S. Chamber of Commerce
Episode: Are We Ready for a New Age of Cyber Threats?
Dennis Ross
Ambassador, counselor at the Washington Institute for Near East Policy; author
Washington Institute for Near East Policy
Episode: Can Diplomacy Resolve the Iran Crisis?
Josh Lipsky
Vice President and Chair of International Economics at the Atlantic Council
Atlantic Council
Episode: Has the Seizure of Russian Assets Undermined the Dollar?
Edward Fishman
Author of Choke Points, American Power in the Age of Economic Warfare
Author; previously at Brookings/think tank context inferred
Episode: Has the Seizure of Russian Assets Undermined the Dollar?
Ricaurte Vásquez Morales
Administrator of the Panama Canal Authority
Panama Canal Authority
Episode: Can the Panama Canal Handle the Iran Fallout?

Host

Jay Sapsford
Host of The Call, Global Intelligence Desk (Chamber)

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Talking Points

Recent interactions between the hosts and their guests.

Can the Defense Industrial Base Meet the Moment?
Q: What is the role of AI across the battlefield and in back-office operations?
AI serves as a priority not only for advanced weapons and battlefield analytics but also for predictive maintenance, personnel management, and data processing, enabling more efficient, faster decision-making and operation optimization.
Can the Panama Canal Handle the Iran Fallout?
Q: How does the neutrality treaty affect how the canal operates during crisis?
The treaty provides a framework that prevents the canal from being dictated by any single party, allowing market mechanisms and collaboration with US agencies to govern priority while keeping transit open to all nations.
Are We Ready for a New Age of Cyber Threats?
Q: Are they going to be using AI to do that, do you think?
AI will be used to both defend and attack more rapidly. Defenders can leverage AI to automate scanning, patching, and real-time threat detection, while attackers can automate more sophisticated attacks. The balance will hinge on how quickly organizations adopt AI-enabled defense and how they manage patching at scale.
Are We Ready for a New Age of Cyber Threats?
Q: Bill, let's start with the basics. What is Mythos and why is it getting so much attention?
Mythos is a large language model designed by Anthropic not specifically for security, but exceptionally good at finding flaws in technology systems. It accelerates vulnerability analysis, potentially democratizing capabilities that were previously limited to a few. The key impact is the speed and scale at which vulnerabilities can be discovered and exploited.
Should the U.S. Treasury Be an Agency of National Security?
Q: Should the U.S. Treasury be an instrument of national security, and how should it be used going forward?
It should be an instrument of national security, but with extreme care to avoid overreach. It requires clear aims, norms, and incentives for financial inclusion that still allow the U.S. to influence illicit behavior without undermining global financial stability.

Audience Metrics

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Frequently Asked Questions About The Call by the Global Intelligence Desk

What is The Call by the Global Intelligence Desk about and what kind of topics does it cover?

A high-signal series focused on geopolitics, macro policy, and global risk, with episodes that dissect sanctions, great-power competition, defense industrial base dynamics, cyber threats, and major regional flashpoints. Guests are senior policymakers, former diplomats, and leading thinkers from think tanks and international institutions, offering practical implications for business strategy, risk management, and strategic planning. Notable throughlines include the evolving role of economic statecraft, the interplay between US policy and global markets, and ambitious space and technology policy shifts. The show stands out for its blend of historical context, policy analysis, and forward-looking scenarios relevant to corporate decision-makers... more

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1. WITA's Friday Exchange
2. The Asia Chessboard
3. The Foreign Affairs Interview
4. WSJ Opinion: Potomac Watch
5. All-In with Chamath, Jason, Sacks & Friedberg

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The Call by the Global Intelligence Desk launched a year ago and published 79 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Call by the Global Intelligence Desk?

Recent guests on The Call by the Global Intelligence Desk include:

1. Eliot Cohen
2. Manoj Pradhan
3. Jeremie Waterman
4. Juan Zarate
5. Bill Jewell
6. Dennis Ross
7. Josh Lipsky
8. Edward Fishman

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