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ON CRISPR: The Story of Jennifer Doudna with Walter Isaacson

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A single scientific breakthrough changed the future of humanity, setting off the third great revolution of modern times. As with any revolution, things didn’t happen neatly or quietly. One figure stood at the center of it all: Jennifer Doudna, the Nobel Prize-winning biochemist who co-created CRISPR. Her invention signified the arrival of a newfound ability to edit our genes, as simply as we edit ... more

PublishesWeeklyEpisodes17Founded2 years ago
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TechnologySociety & Culture

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Artwork for ON CRISPR: The Story of Jennifer Doudna

Latest Episodes

In the four years since the book’s publication, CRISPR has revolutionized the world of medical treatments and possibilities. But our world has changed drastically, too. As AI’s impact grows, U.S scientists are facing funding cuts like never before. F... more

As the gene editing field kept growing, so did the dangers. Back in 2018, Jennifer Doudna received an email from a Chinese scientist claiming that he had genetically edited two twin babies. The news reverberated across the world and made Doudna and h... more

Jennifer Doudna thought she had won the race. She thought she had beaten out all scientific competitors when she and her co-author had shocked the world with their groundbreaking technology for gene editing. But turned out, the race had just gotten f... more

Back in the 1990s, a young microbiologist in Alicante, Spain became obsessed with a strange pattern he observed in the genes of tiny organisms — a series of inexplicable clusters. And he wasn’t alone. All around the world, a network of scientists wer... more

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Recent Guests

George Church
Harvard medical professor, geneticist, and co-founder of Colossal Biosciences
Colossal Biosciences
Episode: ON CRISPR Episode 3: Patent Wars

Reviews

3.8 out of 5 stars from 484 ratings
  • Why so Sensitive Elon Sycophants?

    “Leftist leanings”? No, just real. A lot of these reviewers have no idea how Leftist talk about Elon.

    Apple Podcasts
    5
    Daphdaniel
    United States8 months ago
  • Very interesting

    Well researched and paced. I didn’t realize how little I knew about Benjamin Franklin!

    Apple Podcasts
    5
    snksnenwjwkwkwiwidnd
    United Statesa year ago
  • Had potential but…

    As others have said, it comes from a left wing biased point of view. Not presented objectively it is similar to MSM.

    Apple Podcasts
    1
    cip33q
    United Statesa year ago
  • Trump dig, really?

    Good podcast on Ben Franklin until a modern political slam. This will be deleted as soon as I submit this. I had been looking forward to the Musk episodes.

    Apple Podcasts
    1
    Dannypicard
    United Statesa year ago
  • A wonderful author and speaker.

    Walter Isaacson is a prolific author. Thank you Walter for another wonderful insight into a fascinating person.

    Apple Podcasts
    5
    HLLHB
    United Statesa year ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Listeners appreciate the well-researched narratives and engaging storytelling.
Some reviews indicate concerns about perceived biases in the host's framing of topics, especially regarding political discussions.
The discussion of ethical implications in science and technology resonates well with an informed audience.
The exploration of historical figures is seen as both informative and relevant to contemporary discussions.
Listeners generally commend the depth of knowledge and insight shared by the hosts.

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Talking Points

Recent interactions between the hosts and their guests.

ON CRISPR Episode 4: Franken Monsters
Q: What was their general conclusion coming out of these meetings about inheritable gene edits?
Don't make inheritable gene edits, as it presents moral implications and challenges that we are not yet ready to confront.
ON CRISPR Episode 4: Franken Monsters
Q: Can you explain to what extent CRISPR itself played a role in the vaccines that we know now versus treatments that may come down the line?
CRISPR technology is not the same as mRNA vaccines, but both involve the use of RNA as a programming molecule. CRISPR has a role in creating treatments and vaccines but operates differently than mRNA technology.
ON Musk Episode One: Genius
Q: Was absolutely everything on the record, or were there times when some executive from some other part of the company or someone tried to say, this is off the record?
Isaacson describes Musk's openness to him being present, although there were some exceptions regarding national security classified briefings.
ON Musk Episode One: Genius
Q: Could you tell me the story of how this book first came about, the first seed that this book could be possible?
Walter Isaacson explains how a mutual friend set up a conversation with Elon Musk, leading to an unusual agreement for a biography.
ON Musk Episode Three: Storytelling and Hot Takes
Q: How did you start to formulate an idea of what you owe that person when you spend time with them?
I always tried to see if you could combine both access and investigative journalism.

Audience Metrics

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Frequently Asked Questions About ON CRISPR: The Story of Jennifer Doudna

What is ON CRISPR: The Story of Jennifer Doudna about and what kind of topics does it cover?

The content focuses on pivotal figures in science and technology, particularly looking at Jennifer Doudna's groundbreaking work with CRISPR and the societal implications of gene editing. The storytelling blends personal narratives with broader historical contexts, showcasing Doudna's journey as a Nobel Prize-winning biochemist who revolutionized genetic engineering. Additionally, episodes delve into the life of Benjamin Franklin, exploring his impact on American society as a statesman, inventor, and writer. The discussions are enriched with insights into the ethical dimensions of scientific advancements and the competitive landscape surrounding influential individuals in history, such as Elon Musk.

What sets this content apart is the blend... more

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ON CRISPR: The Story of Jennifer Doudna launched 2 years ago and published 17 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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Recent guests on ON CRISPR: The Story of Jennifer Doudna include:

1. George Church

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