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In the Know with Amol Sarva

Amol Sarva
Venture Capital
Metabolic Health
New York Tech
Obesity
Artificial Intelligence
Glp-1 Agonists
Healthtech
Techbio
Diabetes
Nutrition
Longevity
Glp-1 Medications
Personal AI
Mrna Cancer Vaccines
Pain Management
Longevity Movement
Healthcare
New York Tech Ecosystem
Gut Health
Gut Microbiome

Amol Sarva's series with changemakers and innovators in longevity, tech, and ideas

PublishesTwice monthlyEpisodes94Founded7 years ago
Categories
ScienceBusiness

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Artwork for In the Know

Latest Episodes

🎙️ Episode Guide — PJ Parson (Northzone)

Welcome to my series on OG NY Tech Celebrating 30 years of the New York tech ecosystem, from 1995 to now.

PJ Parson is a partner at Northzone, best known for backing Spotify when it expanded to New York in ... more

>updated with vibier sound!<

Welcome to my series on OG NY Tech

Celebrating 30 years of the New York tech ecosystem, from 1995 to now.

Kevin Ryan joined DoubleClick in 1996, just months after it was founded—and helped turn it into the most importa... more

Welcome to my series on OG NY Tech -- celebrating 30 years of NY tech ecosystem, from 1995 to now.

Howard Morgan started as an engineer and professor in the early computing days, and ended up building three (four? five?) huge and import investment g... more

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Recent Guests

PJ Parson
Investment professional and partner at Northzone, with notable contributions to the tech startup ecosystem and investments in Spotify.
Northzone
Episode: PJ Parson, Northzone and Spotify
John Borthwick
Founder of BetaWorks and a significant figure in New York's tech scene
BetaWorks
Episode: John Borthwick, Betaworks
Dr. Will Bulsiewicz
Gut biome expert and medical director at Zoe
Zoe
Episode: Soluble and insoluble fiber, food and gut health and their role in overall health with Dr. Will Bulsiewicz from Zoe
Derek Huffman
Expert in metabolic health, pharmacology, and exercise physiology
Einstein College of Medicine
Episode: How food becomes energy and the view from sports nutrition on metabolism with Professor Derek Huffman of Einstein
Dr. Jeff Alfonsi
Co-founder of RxFood and a practicing MD
RxFood
Episode: Food as medicine with physician and founder Jeff Alfonsi
Matt Kaeberlein, Ph.D.
Leading researcher in longevity and metabolic health.
OptiSpan
Episode: Metformin, Rapamycin, the cellular mechanisms at the cutting edge of weight loss and longevity with Matt Kaeberlein, Ph.D.
Randy Seeley
Nutrition professor and expert in obesity and metabolic health
Michigan
Episode: Bariatric surgery, the gut biome, and the interactions that create weight loss with surgery and nutrition professor Randy Seeley, Ph.D. at Michigan
Dr. Waj Mehal
Hepatologist at Yale
Yale University Hospital
Episode: How weight loss works with Yale’s Dr. Waj Mehal
James Peyer
Ph.D. and expert on metabolic health and aging biology
Cambrian Bio
Episode: How Ozempic works and what else could revolutionize metabolic health with James Peyer, Ph.D. of Cambrian Bio

Host

Amol Sarva
Host of In the Know

Reviews

4.6 out of 5 stars from 16 ratings
  • Inspiring!

    I most recently listened to Saeju Jeong's story on Noom. Very inspiring to say the least. I wonder if I have the courage to be almost bankrupt in order to build a successful company. Hope all is well, professor!

    Apple Podcasts
    5
    HeyHomieBaby
    Mexico6 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Consistently high-quality guests and candid discussions on AI and healthcare.
Great mix of founders and investors; practical lessons for scaling.
Thoughtful, insightful conversations with industry leaders.

Top Business Podcasts

Talking Points

Recent interactions between the hosts and their guests.

Kevin Ryan, Alleycorp + MongoDB ++ Doubleclick, Dilbert
Q: What advice would you give to young entrepreneurs starting out?
Get to the right city and recognize that building a business takes time and persistence, as success often follows the right conditions and timing.
Kevin Ryan, Alleycorp + MongoDB ++ Doubleclick, Dilbert
Q: What are the biggest challenges you faced when launching MongoDB?
The early years were slow; we had no revenues initially for three years, as people were hesitant to adopt the product.
*Fred Wilson, Union Square Ventures
Q: What's your take on the future for New York's tech scene?
New York was growing faster than Silicon Valley in the last decade, but now Silicon Valley is growing faster again, especially with AI.
*Fred Wilson, Union Square Ventures
Q: What do you think makes a great venture investor?
It's about being passionate about an idea and supporting the founder wholeheartedly once the investment is made.
How food becomes energy and the view from sports nutrition on metabolism with Professor Derek Huffman of Einstein
Q: How do fasting and caloric restriction relate to metabolic response?
Fasting is fundamental to caloric restriction, leading to important biological responses such as autophagy and cell maintenance.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Gender Skew
Location
Interests
Professions
Age Range
Household Income
Social Media Reach

Frequently Asked Questions About In the Know

What is In the Know about and what kind of topics does it cover?

This series spotlights leaders and builders shaping tech, longevity, and healthcare, with frequent deep dives into entrepreneurship, venture capital, and the evolving New York tech ecosystem. Episodes often explore how AI and biotech intersect with business strategy, the challenges of funding and scaling startups, and the geopolitical factors influencing innovation. A notable strength is the host's knack for extracting practical wisdom from a diverse set of guests, from early-stage founders to seasoned investors, making it valuable for founders, operators, and investors looking for strategic context and actionable insights.

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Which podcasts are similar to In the Know?

These podcasts share a similar audience with In the Know:

1. All-In with Chamath, Jason, Sacks & Friedberg
2. Invest Like the Best with Patrick O'Shaughnessy
3. Pivot

How many episodes of In the Know are there?

In the Know launched 7 years ago and published 94 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on In the Know?

Recent guests on In the Know include:

1. PJ Parson
2. John Borthwick
3. Dr. Will Bulsiewicz
4. Derek Huffman
5. Dr. Jeff Alfonsi
6. Matt Kaeberlein, Ph.D.
7. Randy Seeley
8. Dr. Waj Mehal

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