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Invest Like the Best with Patrick O'Shaughnessy

Colossus | Investing & Business Podcasts
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Conversations with the best investors and business leaders in the world. We explore their ideas, methods, and stories to help you better invest your time and money. Hear stock market and boardroom insights you can't find anywhere else. If you're a professional investor, CEO, entrepreneur, or business strategist, this is for you. Explore all our episodes and learn more at www.colossus.com

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Latest Episodes

My guest today is Krishna Rao, the CFO of Anthropic. The center of our conversation is how he navigates the decision around procuring and allocating compute, which he describes as the canvas on which everything else gets built.

We talk about what he... more

My guest today is Brian Chesky, the co-founder and CEO of Airbnb. Our conversation traces the path from his early training as an industrial designer at RISD through the pandemic moment that forced him into founder mode.

He explains why he thinks AI ... more

My guest today is Paul Tudor Jones. Paul is the founder of Tudor Investment Corporation and one of the greatest macro traders of all time, known for calling and profiting from the 1987 crash and compounding capital at extraordinary rates over more th... more

This is my second conversation with Dylan Patel. Dylan is the founder and CEO of SemiAnalysis, where he tracks the semiconductor supply chain and AI infrastructure buildout.

This conversation is about the supply and demand of tokens. On demand, Dyla... more

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Recent Guests

Krishna Rao
CFO of Anthropic
Anthropic
Episode: Krishna Rao - Anthropic's CFO on Compute, Scaling to $30B ARR, and the Returns to Frontier Intelligence - [Invest Like the Best, EP.472]
Brian Chesky
Co-founder and CEO of Airbnb
Airbnb
Episode: Brian Chesky - AI Founder Mode - [Invest Like the Best, EP.471]
Paul Tudor Jones
Legendary trader and investor
Robbin Hood, Tudor Investment Corporation
Episode: Paul Tudor Jones - Lessons From 50 Years in Markets - [Invest Like the Best, EP.470]
Alex Karnal
Bio and healthcare investor
Braidwell
Episode: Alex Karnal - The Trillion-Dollar Health Revolution - [Invest Like the Best, EP.468]
Scott Nolan
Scott Nolan. Early SpaceX employee, former investor at Founders Fund, founder of General Matter
General Matter
Episode: Scott Nolan - SpaceX, Founders Fund, and Rebuilding American Uranium Enrichment - [Invest Like the Best, EP.467]
Sergey Levine
Co-founder and researcher at Physical Intelligence
Physical Intelligence
Episode: Sergey Levine - Building LLMs for the Physical World - [Invest Like the Best, EP.465]
Mitchell Green
Founder of Lead Edge Capital
Lead Edge Capital
Episode: Mitchell Green - Lessons from Cold Calling 10,000 Companies - [Invest Like the Best, EP.464]
William Hockey
Founder of Column; former co-founder of Plaid
Column
Episode: William Hockey - Building the Operating System for the Dollar and Silicon Valley Heresy - [Invest Like the Best, EP.463]
Shyam Sankar
CTO of Palantir Technologies
Palantir Technologies
Episode: Shyam Sankar - Celebrating Heretics - [Invest Like the Best, EP.462]

Host

Invest Like the Best with Patrick O'Shaughnessy
Conversations with the best investors and business leaders in the world. We explore their ideas, methods, and stories to help you better invest your time and money. Hear stock market and boardroom insights you can't find anywhere else. If you're a professional investor, CEO, entrepreneur, or business strategist, this is for you. Explore all our episodes and learn more at https://www.joincolossus.com

Reviews

4.8 out of 5 stars from 4.8k ratings
  • I initially invested a total of $105,000 over a period of 5 weeks with my broker. My bonus/profit was $830,000, every attempt to make withdrawal failed and I was instructed to make another deposit of $25,000 before I can make withdrawals which I did. Up till now, I’m still unable to make withdrawals and all attempt to contact broker has failed. This is very pathetic and I felt so bad losing my investment. I did a due diligence test before investing with them but guess what I ended up getting bur... more

    Podchaser
    5
    barrjacquelinepierce
    2 months ago
  • Must listen to podcast for anyone interested in investing

    Patrick’s interview style can only be described as awesome! He asks insightful questions and lets his guests do the talking. His ability to uncover the most interesting parts of the guests’ experience is unparalleled. I look forward to each episode.

    Apple Podcasts
    5
    Leon_D_NYC
    United States2 months ago
  • Josh Kushner episode not for me

    People have overhyped this guy so much, I was looking forward to learning something from ‘Josh at Thrive Capital’. Stopped the podcast episode on at least three occasions. My god, if I knew nothing about investing, I would say this episode sounds like two corporate robots parroting to each other isms about jack squat. Still don’t know what Josh has done to achieve whatever has brought this level of hype.

    Apple Podcasts
    1
    TheCashflowOperator
    United States2 months ago
  • So disappointed

    I’ve been a long time fan & listener of the pod for years and years. Was really the only podcast that I made time for, even tried to listen to some of the other offerings through Colossus, although they are all significantly less interesting than ILTB, but I have stopped listening all together after the Kushner interview. That was straight propaganda meant to smooth over the transition back into Trump’s presidency. Every question was a total softball & I cannot believe that Patrick took the mone... more

    Apple Podcasts
    1
    themissusallhall
    United States2 months ago
  • What Guides the Work We Do

    This episode felt like a gift because it reminded me that work becomes meaningfully impactful when it’s rooted in a guiding principle rather than just metrics or milestones. Hearing Patrick reflect on how he leaned into curiosity, championed overlooked talent, and let an instinct for discovery shape his path invites listeners to take stock of their own compass. Not for external applause, but for enduring satisfaction. You helped frame a journey where purpose leads before profit, and that perspec... more

    Apple Podcasts
    5
    Anum — The Platinum CEO
    United Kingdom4 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Trend analysis and insights into the market are valued highly among the audience, who find them informative and timely.
Overall, the tone is very positive, with many calling it an essential listen for aspiring and established investors alike.
The quality of guests enhances the learning experience, although some criticism arises around specific controversial guests.
Many reviews emphasize the host's skill in balancing interviews while allowing guests ample opportunity to express their ideas.
Listeners appreciate the depth of engagement in interviews, which invite introspection and derive lessons applicable to a wide audience.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Paul Tudor Jones - Lessons From 50 Years in Markets - [Invest Like the Best, EP.470]
Q: What does a day in the life look like for you as a trader with decades of experience?
A highly structured routine: early wake, workouts, market open, meetings, strategic planning around the close, then review and prep for the next day, all powered by intense information processing and a plan that guides execution.
Paul Tudor Jones - Lessons From 50 Years in Markets - [Invest Like the Best, EP.470]
Q: What is the difference between being an investor and a trader?
He explains that investing focuses on long-term secular themes and compounding, often with lower turnover and emphasis on staying patient, while trading relies on acute, moment-to-moment risk assessment and capitalizing on shorter-term inefficiencies with high discipline and planning.
Sergey Levine - Building LLMs for the Physical World - [Invest Like the Best, EP.465]
Q: What literally have you done and are you doing to make that happen?
The approach combines foundational vision-language-action models with reinforcement learning, and iteratively improves through high-level instructions and semantic labeling to shift bottlenecks from control to interpretation.
Mitchell Green - Lessons from Cold Calling 10,000 Companies - [Invest Like the Best, EP.464]
Q: Talk to me about the 10,000 calls. What did you learn calling that many companies?
Discipline stands out; most things are noise, focus on identifying the truly investable Lead Edge signals, and you learn responsiveness and follow‑through from entrepreneurs who actually do what they say.
Shyam Sankar - Celebrating Heretics - [Invest Like the Best, EP.462]
Q: How does AI fit into Palantir's architecture and value delivery?
AI will create value at the chips and ontology layers, with applications built on top; the platform enables rapid, enterprise-wide decision-making and programmable business processes.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About Invest Like the Best

What is Invest Like the Best about and what kind of topics does it cover?

Conversations feature a range of prominent investors and business leaders, discussing unique insights, strategies, and philosophies regarding investment and entrepreneurship. Key themes include public and private market dynamics, venture capital, operational excellence in business management, and the integration of technology and innovation in investment strategies. Episodes often explore thought-provoking intersections, such as how artificial intelligence is reshaping various industries and how personal narratives influence investment philosophies. The engaging and knowledgeable host drives meaningful conversations, ensuring listeners gain insights into the complex world of finance and entrepreneurship. This podcast is distinguished by its... more

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Which podcasts are similar to Invest Like the Best?

These podcasts share a similar audience with Invest Like the Best:

1. Capital Allocators – Inside the Institutional Investment Industry
2. Business Breakdowns
3. Founders
4. The a16z Show
5. Value Investing with Legends

How many episodes of Invest Like the Best are there?

Invest Like the Best launched 10 years ago and published 578 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Invest Like the Best?

Recent guests on Invest Like the Best include:

1. Krishna Rao
2. Brian Chesky
3. Paul Tudor Jones
4. Alex Karnal
5. Scott Nolan
6. Sergey Levine
7. Mitchell Green
8. William Hockey

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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