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Weight Loss And ...

Holly Wyatt & James Hill
Weight Loss
Obesity
Nutrition
Physical Activity
Glp-1 Medications
Weight Management
Exercise
Mindset
Metabolism
Weight Loss Maintenance
Weight Loss Medications
Weight Loss Plateau
Motivation
Type 2 Diabetes
Food Noise
Ultra-Processed Foods
Energy Balance
Bariatric Surgery
National Weight Control Registry
Holiday Weight Gain

Your go-to hangout for everything weight loss… and beyond! “Weight Loss and…” is brought to you by the University of Alabama at Birmingham (UAB) and hosted by seasoned experts in weight management, Dr. James Hill and Dr. Holly Wyatt. We’re your friendly guides through the maze of weight loss, but with a fun twist. We’re not here to preach the latest fad diet or promise a miracle workout. Instead, ... more

PublishesWeeklyEpisodes135Founded3 years ago
Number of ListenersCategories
FitnessHealth & FitnessNutrition

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Artwork for Weight Loss And ...

Latest Episodes

For decades, one number has ruled the world of fitness: 10,000 steps. It's on your watch, your phone, maybe even tattooed into your daily to-do list. But what if that number was never based on science at all?

Join Holly and Jim as they sit down with... more

For 40 years, every time nutrition has found a new villain, the food industry has handed us a new label to go with it: non-fat, no GMOs, gluten-free, no seed oils, and now, non-ultra-processed. We have more experts, more studies, and more food rules ... more

Losing weight on a GLP-1 medication can feel like magic until the scale stops moving. For almost everyone on these drugs, there comes a moment when the rapid progress slows, then stalls completely. Is the medication failing? Has your metabolism adapt... more

What if the biggest obstacle to your health isn't your willpower, it's your zip code? Most of us have been raised to believe that weight and health come down to personal choices: what you eat, how much you move, how disciplined you are. But what if t... more

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Recent Guests

Christina Economos
Dean of the Friedman School of Nutrition Science & Policy at Tufts University
Tufts University
Episode: The Hidden Influence of Community and Environment with Christina Economos
Maha Tahiri
Nutrition scientist, food industry strategist, founder of Nutrition Sustainability Strategies
Nutrition Sustainability Strategies
Episode: Why Dietitians Matter More Than Ever with Maha Tahiri
Ken Fujioka
Endocrinologist, director of the Nutrition and Metabolic Research Center at Scripps Clinic
Scripps Clinic, San Diego
Episode: What Comes After GLP-1 Success with Ken Fujioka
Arne Astrup
Nutrition scientist and former head of a leading European nutrition research department
Episode: What the Nutrition Guidelines Still Haven't Caught Up To with Arne Astrup
Renee Rogers
Senior scientist at University of Kansas Medical Center; expert in bio-behavioral healthy lifestyle interventions and engagement strategies
University of Kansas Medical Center
Episode: Exercise Isn't What You Think It Is Anymore with Renee Rogers
Rudy Leibel
Christopher J. Murphy Memorial Professor of Diabetes Research at Columbia University, expert in obesity biology
Columbia University
Episode: Why Your Body Fights After Weight Loss with Rudy Leibel
Daniel Lieberman
Professor of human evolutionary biology at Harvard University, paleoanthropologist
Harvard University
Episode: The Evolutionary Truth Behind Why Exercise Feels So Hard with Daniel Lieberman
Christopher Gardner
Professor of Medicine at Stanford University; Director of Nutrition Studies at Stanford Prevention Research Center
Stanford University
Episode: The Making of the 2025 Dietary Guidelines and What They Mean for You with Christopher Gardner
Penny Kris-Etherton
Evan Pugh University Professor of Nutrition Sciences Emeritus, leading researcher in diet and cardiovascular health
Penn State University
Episode: Why Your Spice Rack Is Your Best Health Tool with Penny Kris-Etherton and Kristina Petersen

Hosts

Jim Hill
Host of Weight Loss And; long-time clinician and researcher with UAB affiliations and a history at Weight Loss And.
Holly Wyatt
Co-host of Weight Loss And; experienced clinician with university backing and role in public health-focused obesity discussions.

Reviews

4.9 out of 5 stars from 34 ratings
  • I like it but…

    I’ve listened to basically all episodes. I love the interviews with excellent experts. Holly and Jim’s bias seems to be against long term use of GLP1s. I use Zepbound and it 100% allows me maintain all of my healthy habits to maintain my 40 lb loss for over a year. I’ve never been able to maintain with such ease. GLP1 meds are MAINTENANCE meds. Also antidotes have nothing to do with anecdotes!!

    Apple Podcasts
    4
    ZepWinner
    United States2 months ago
  • Science and soul

    Love the thoughtful questions Dr Holly and Dr Hill ask their guests. My favorite episodes are their solo ones where you get to hear their take on GLP1s, what it takes to maintain weight loss, and especially the mind state of successful weight loss.

    I always learn something when I listen.

    Apple Podcasts
    5
    Lizzie_Merritt
    United States5 months ago
  • New book

    Will your new book on getting off weight loss medication have a robust actual plan to follow for weight management? My doctor doesn’t know how to help do the weight management piece. Lost a good amount of weight but 1 year after it’s all back…despite a health exercise, including resistance training. Want to do the glp 1 again…but with an actual exit strategy.

    Apple Podcasts
    5
    sminnesota
    United Statesa year ago
  • Tech

    Loved the episode with Deborah Tate!

    Apple Podcasts
    5
    GEMs2023
    United Statesa year ago
  • Great episode with tips to avoid self sabotage.

    I took little nuggets away from this episode-power of positivity, combining weight loss …AND. During the episode it became clear to me that in addition to weight loss, I want to be fit, lean, and strong. I want that extra energy. Feeling more motivated after listening! 😊💪🏼🦵

    Apple Podcasts
    5
    McMtnMom
    United States2 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Some episodes note a perceived bias against long-term GLP-1 use, which is a recurring feedback point.
Listeners appreciate practical, science-backed guidance and real-world tips.
Experts drive the conversations and guests bring strong credibility.

Chart Rankings

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Talking Points

Recent interactions between the hosts and their guests.

The Science and Realities of Long-Term GLP-1 Use
Q: Why does weight loss slow down on GLP-1 medications and what is a plateau?
Weight loss slows as the body reaches a new energy balance; the drugs reduce intake and the body lowers energy expenditure, leading to a plateau that is normal and expected rather than a sign of failure.
The Hidden Influence of Community and Environment with Christina Economos
Q: How do you approach getting a community ready for intervention and ensuring sustainability?
Readiness, trust-building, stakeholder involvement, data harmonization, co-design and implementation, and ensuring results are shared with a plan for sustainability are essential to successful community interventions.
The Hidden Influence of Community and Environment with Christina Economos
Q: Shape Up Somerville—what were you actually trying to do and what surprised you the most?
We designed a multi-level, community-based intervention to prevent childhood obesity by creating a surround-sound of healthy options across schools, homes, restaurants, and neighborhoods, which led to a measurable improvement in BMI and spillover benefits to families.
The Hidden Influence of Community and Environment with Christina Economos
Q: What pulled you into working with communities?
I was motivated by a desire to replicate the success of other social change movements—like seat belts and recycling—by applying those same elements to obesity prevention, aiming for population-wide impact rather than one-on-one work.
What Comes After GLP-1 Success with Ken Fujioka
Q: How do you personalize treatment for a patient, given cost and coverage concerns?
He explains starting with what is covered or affordable, then selecting medications based on patient characteristics (e.g., diabetes status, postmenopausal women), and using pills when injections are impractical or too costly.

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Frequently Asked Questions About Weight Loss And ...

What is Weight Loss And ... about and what kind of topics does it cover?

A practical, science-backed show exploring weight management, obesity, nutrition, and exercise through expert interviews and real-world experiences. Topics span GLP-1 medications, maintenance vs. active weight loss, nutrition guidelines, and the evolving role of movement in metabolic health. Episodes emphasize evidence, personalized approaches, and sustainable lifestyle changes, with a pragmatic, no-heroic-fix stance and a hint of humor that keeps conversations approachable. Unique strengths include a steady stream of university-affiliated researchers and clinicians, plus clinicians with decades of clinical wisdom sharing actionable insights for both individuals and industry listeners seeking credible, research-informed perspectives.

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1. Docs Who Lift
2. GLP-1 Hub: Support, Community, and Weight Loss
3. Fat Science
4. Optimal Protein Podcast with Vanessa Spina
5. The Obesity Guide with Matthea Rentea MD

How many episodes of Weight Loss And ... are there?

Weight Loss And ... launched 3 years ago and published 135 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Weight Loss And ...?

Recent guests on Weight Loss And ... include:

1. Christina Economos
2. Maha Tahiri
3. Ken Fujioka
4. Arne Astrup
5. Renee Rogers
6. Rudy Leibel
7. Daniel Lieberman
8. Christopher Gardner

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