The Tell-Tale Heart: The Pharmacist's Cardiovascular Digest

Heart Failure

Hypertrophic Cardiomyopathy

American College Of Cardiology

Oceanic Stroke Trial

Polypill

Inflammation

PCSK9 Inhibitors

LDL Cholesterol

Poly-Hf

Cardiac Myosin Inhibitors

Hypertension

Adipokine Hypothesis

American Heart Association (AHA) Meeting

Vesalius Trial

Coral Reef Study

Zalunfiban

Heart Failure With Reduced Ejection Fraction

Heartlife Canada

Cardiac Transplant

Pharmacists

This podcast delivers concise clinical updates in cardiology alongside insightful career stories from pharmacists in the field. Host Craig Beavers, PharmD, FACC, FAHA, FCCP, BCCP, CACP, provides essential knowledge and practical perspectives for pharmacy professionals specializing in cardiovascular care.

11 ratings

Publishes	Twice monthly	Episodes	33	Founded	a year ago
Number of Listeners		Categories	ScienceLife Sciences

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Latest Episodes

32: What's Making Headlines in Cardiovascular Care: A Pharmacist's Breakdown of the Latest Breakthroughs

In this mini news episode of the Tell-Tale Heart podcast, host Craig Beavers, PharmD, FACC, FAHA, FCCP, BCCP, BCPS-AQ Cardiology, CACP, highlights three major developments in cardiovascular and cardiometabolic medicine that pharmacists should have on... more

27 May 2026 • 8 min

31: From Misdiagnosis to Advocacy: Addressing Bias and Equity in Heart Failure Management

In this episode of The Tell-Tale Heart, host Craig Beavers, PharmD, FACC, FAHA, FCCP, BCCP, BCPS-AQ Cardiology, CACP, speaks with Rhonda Monroe, MBA, a heart failure survivor and lead advocate at HeartLife, about her lived experience with spontaneous... more

12 May 2026 • 53 min

30: Debriefing ACC 2026: Key Cardiovascular Trials and Their Clinical Implications for Pharmacists

In this episode of The Tell-Tale Heart: The Pharmacist's Cardiovascular Digest, host Craig Beavers, PharmD, FACC, FAHA, FCCP, BCCP, BCPS-AQ Cardiology, CACP, welcomes back Kyle Fischer, PharmD, BCCP, MBA, a cardiology clinical pharmacy specialist at ... more

28 Apr 2026 • 55 min

29: New Dyslipidemia Guidelines Restore LDL Goals and Expand Pharmacist Opportunities

In this episode of the Tell-Tale Heart podcast, host Craig Beavers, PharmD, FACC, FAHA, FCCP, BCCP, BCPS-AQ Cardiology, CACP, is joined by Joseph Saseen, PharmD, BCPS, BCACP, CLS, and Dave Dixon, PharmD, FACC, FAHA, FCCP, FNLA, BCACP, CLS, to discuss... more

31 Mar 2026 • 48 min

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Recent Guests

Rhonda Monroe

Heart failure survivor, advocate for heart patients globally

HeartLife; Women Heart; Boost (Better Outcomes, Optimal Scientific Therapies)

Episode: 31: From Misdiagnosis to Advocacy: Addressing Bias and Equity in Heart Failure Management

Joe Sassine

Associate Dean for Clinical Affairs and Professor at the University of Colorado

University of Colorado

Episode: 29: New Dyslipidemia Guidelines Restore LDL Goals and Expand Pharmacist Opportunities

Dave Dixon

Professor and Chair of the Department of Pharmacotherapy and Outcome Science at Virginia Commonwealth University

Virginia Commonwealth University

Episode: 29: New Dyslipidemia Guidelines Restore LDL Goals and Expand Pharmacist Opportunities

Kristen Campbell

Clinical pharmacist at Duke University focusing on electrophysiology

Duke University Medical Center

Episode: 27: Pharmacists’ Evolving Role in Electrophysiology Takes Center Stage Ahead of ACC 2026

Allison Burnett

Thrombosis and hemostasis pharmacist at the University of New Mexico Hospital; residency program director for PGY-2 thrombosis and hemostasis

University of New Mexico Hospital

Episode: 28: Unpacking the 2025 ACC/AHA Pulmonary Embolism Guidelines With a Thrombosis Pharmacist

Ambers Fendi

Cardiologist, UT Southwestern Medical Center, Dallas, Texas

UT Southwestern Medical Center

Episode: 25: How the POLY-HF Trial Shows Pharmacists' Key Role in Heart Failure Care

Nick Miller

Compounding pharmacist, Pharmacy Solutions

Pharmacy Solutions

Episode: 25: How the POLY-HF Trial Shows Pharmacists' Key Role in Heart Failure Care

Andrew Williford

Assistant Professor at UC San Diego Skag School of Pharmacy and Pharmaceutical Sciences; clinician managing cardiac myosin inhibitors and HCM patients

UC San Diego Health; UC San Diego Health (clinic)

Episode: 24: Hypertrophic Cardiomyopathy: What Pharmacists Need to Know in 2026

Marc Baines

Co-founder and executive director of HeartLife Canada

HeartLife Canada

Episode: 22: From Diagnosis to Transplant: A Heart Failure Patient’s Journey and the Pharmacists’ Impact Along the Way

Host

Craig Beavers

Host of cardiovascular pharmacotherapy updates and practitioner-focused discussions.

Reviews

4.9 out of 5 stars from 11 ratings

Keep it up!
Every episode has been worth listening to! Insightful topics and expert guests!
Apple Podcasts
5
Jpluenneke
United States8 months ago
Big fan already!
Informative and entertaining. I’m excited to see what else Craig has in store.
Apple Podcasts
5
Baker0621
United Statesa year ago
Can’t wait!!!
I am so excited for this!
Apple Podcasts
4
thisnicknameistakenalso
United Statesa year ago

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Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Listeners value the concise, clinically grounded updates.

Guests come from diverse pharmacy and academic backgrounds.

Show framing helps sponsors understand practical impact on practice.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts	#164	United States/Science/Life Sciences
Apple Podcasts	#58	Philippines/Science/Life Sciences
Apple Podcasts	#124	Israel/Science/Life Sciences
Apple Podcasts	#204	Taiwan/Science/Life Sciences

Talking Points

Recent interactions between the hosts and their guests.

19: Jazzed Up for American Heart Association 2025 in New Orleans

Q: How might the Celebrate study's ambulance-based administration of a GP IIb/IIIa inhibitor translate to the U.S. EMS system?

While the trial shows promising safety and efficacy signals, practical implementation in the U.S. would require coordinating EMS protocols, drug storage, costs, and hospital workflows to enable pre-hospital administration, with outcomes tracked over 30 days.

19: Jazzed Up for American Heart Association 2025 in New Orleans

Q: What is the Poly-HF trial aiming to prove, and how could it change standard heart failure therapy?

It aims to assess whether a poly-pill approach combining several GDMT components can improve adherence and outcomes in HFrEF by reducing pill burden and clinical inertia, potentially allowing more patients to receive guideline-directed therapy concurrently.

24: Hypertrophic Cardiomyopathy: What Pharmacists Need to Know in 2026

Q: How do pharmacists educate and manage patients on these new myosin inhibitors, including titration and monitoring?

Pharmacists coordinate education on expected symptom relief, safety monitoring, and the REMS requirements, including regular echocardiograms to monitor ejection fraction and LVOT gradients. They assess drug interactions ( mavacamptan is a 3A4 and 2C19 substrate and inducer; afficamptan is a 2C9 and 3A4 substrate with no enzyme induction) and guide dose adjustments or holds based on EF thresholds. They also manage patient access, enroll in patient assistance programs, and coordinate with specialty pharmacies to streamline imaging and follow-up.

24: Hypertrophic Cardiomyopathy: What Pharmacists Need to Know in 2026

Q: What are the general management strategies for HCM, especially regarding pharmacotherapy and device therapy?

Therapy focuses on reducing contractility. Obstructive HCM commonly uses beta blockers and non-DHP calcium channel blockers as first-line treatments, with disopyramide as an option for stronger negative inotropy. Cardiac myosin inhibitors ( mavacamptan and afficamptan ) provide additional symptom relief and functional improvement, particularly in obstructive disease, but require REMS-based monitoring due to potential EF reductions. For non-obstructive disease, options are limited and ongoing trials of myosin inhibitors are ongoing. Septal reduction therapies are considered if medications are not tolerated or ineffective.

24: Hypertrophic Cardiomyopathy: What Pharmacists Need to Know in 2026

Q: Could you give an overview of what hypertrophic cardiomyopathy is and the different types?

HCM is a genetic disorder characterized by left ventricular hypertrophy and variable obstruction. It is categorized as obstructive (with dynamic LV outflow tract obstruction) or non-obstructive, with obstruction status guiding management strategies and risk assessments for outcomes like sudden cardiac death. Genetic testing and family screening are recommended, and imaging like echo and cardiac MRI help define morphology and fibrosis.

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Frequently Asked Questions About This Podcast

What is This Podcast about and what kind of topics does it cover?

Concise clinical updates in cardiovascular pharmacotherapy paired with practitioner-focused career stories from pharmacists. Episodes frequently cover trial results, guideline implications, and practical workflows for pharmacy teams, with guests ranging from academic lipid and anticoagulation experts to EP pharmacists and patient-advocacy voices. Notable strengths include a clinician-first lens on translating research into practice, a strong emphasis on multidisciplinary care, and interactive previews of major cardiology meetings. This show is likely to appeal to pharmacists and clinicians who want actionable insights, real-world implementations, and a clear view of how emerging data shapes patient care and pharmacy practice.

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1. The Curbsiders Internal Medicine Podcast
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this podcast launched a year ago and published 33 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on this podcast?

Recent guests on this podcast include:

1. Rhonda Monroe
2. Joe Sassine
3. Dave Dixon
4. Kristen Campbell
5. Allison Burnett
6. Ambers Fendi
7. Nick Miller
8. Andrew Williford

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