
PRISM Rounds is a clinical review series by the PRISM research team. Every other week, we break down a high-impact Pulmonary, Critical Care, or Sleep article into three segments: The Blueprint: Study design and methodology. The Math: Demystifying the statistics. The "So What?": Real-world bedside implications. We bridge the gap between the journal and the clinic/ICU, helping you interpret trials q... more
| Publishes | Weekly | Episodes | 66 | Founded | 9 months ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | MedicineHealth & Fitness | |||

When a patient with septic shock requires escalating norepinephrine, should we continue increasing the dose, or introduce multiple vasopressors earlier?
In this episode of PRISM Rounds, we examine the TRICYCLE randomized controlled trial, published ... more
When should we add vasopressin in septic shock? At a norepinephrine dose of 0.1 mcg/kg/min, or should we wait until 0.4?
In this episode of PRISM Rounds, we examine the VASSPR trial, published in JAMA in October 2026. This pragmatic, cluster-randomi... more
Can stimulating the orexin receptor improve both sleepiness and cataplexy in narcolepsy type 1? In this episode of PRISM Rounds, we examine the First Light and Radiant Light phase 3 trials of oveporexton.
Across two 12-week trials, oveporexton produ... more
Choosing between high-flow nasal cannula, noninvasive ventilation (NIV), CPAP, and conventional oxygen is one of the most common decisions in critical care. The new 2026 American Thoracic Society (ATS) Clinical Practice Guideline provides updated, ev... more
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How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.
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Listeners, social reach, demographics and more for this podcast.
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This show functions as a clinical review series focused on pulmonary, critical care, and sleep medicine. Each episode breaks down a high-impact article into three practical segments: study design and methods, the statistical approach, and bedside implications. The hosts translate complex trials into actionable takeaways for clinicians, often weaving physiological rationale with real-world constraints in the ICU or ED. Across episodes, the emphasis is on how new evidence could influence patient care, from treatment choices and workflow to safety considerations and implementation in diverse hospital settings. Noteworthy are the clear focus on actionable bedside guidance, critical appraisal of trial methodology, and the articulation of practic... more
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this podcast launched 9 months ago and published 66 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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