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The Peter Attia Drive

Peter Attia, MD
Metabolic Health
Nutrition
VO2 Max
Alzheimer's Disease
Cardiovascular Disease
Exercise
Longevity
Aging
Glp-1 Agonists
Mental Health
Body Composition
Obesity
Type 2 Diabetes
Cancer
Hair Loss
Exercise Physiology
Nutrition Science
Metabolism
Healthcare
Happiness

Expert insight on health, performance, longevity, critical thinking, and pursuing excellence. Dr. Peter Attia (Stanford/Hopkins/NIH-trained MD) talks with leaders in their fields.

PublishesWeeklyEpisodes453Founded8 years ago
Number of ListenersCategories
MedicineFitnessHealth & Fitness

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In this "Ask Me Anything" (AMA) episode, Peter takes a deep dive into the liver and its central role in metabo... more

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In this episode, Peter sits down with Dr. Linus Abrams, a psychiatrist with nearly 35 years of clinical experi... more

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In this episode, Peter returns to the topic of peptides, offering a clear and accessible guide to a field surr... more

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Jim Otvos is a biophysical chemist who pioneered the use of nuclear magnetic resonance (NMR) spectroscopy to m... more

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Recent Guests

Linus Abrams
psychiatrist with 35 years of experience focused on mood disorders and psychopharmacology
Independent practitioner / Endocrinology-informed psychiatry
Episode: #404 ‒ Mental health beyond neurotransmitters: the role of hormones in psychiatry, why symptom reduction isn't enough, and the future of psychedelic therapies | Linus Abrams, M.D.
Jim Otvos
Biophysical chemist, Liposcience founder
Liposcience/LabCorp
Episode: #402 ‒ NMR blood analysis: how heart disease risk, insulin resistance, inflammation, and mortality risk can be assessed from a single blood sample | Jim Otvos, Ph.D.
Gaia Devi
Neurologist and psychiatrist specializing in memory disorders and cognitive neurology
New York Memory and Healthy Aging Services; Zucker Hofstra Northwell School of Medicine
Episode: #399 ‒ The evolution of Alzheimer's disease and dementia care: how early detection, personalized treatment, new therapies, and a multimodal approach are changing the landscape | Gayatri Devi, M.D.
Renato Tomioka
Dr. Renato Tomioka, reproductive medicine and gynecologic surgery expert
Medical practice (Brazil)
Episode: #397 ‒ Endometriosis and adenomyosis: diagnosis, fertility, reproductive aging, and emerging treatments | Renato Tomioka, M.D., Ph.D.
Lisa Mosconi
Neuroscientist, Neuroimager, and Director of the Women's Brain Initiative at Weill Cornell Medicine
Weill Cornell Medicine
Episode: #381 ‒ Alzheimer's disease in women: how hormonal transitions impact the female brain, the role of HRT, genetics, and lifestyle on risk, and emerging diagnostics and therapies | Lisa Mosconi, Ph.D.
Layne Norton
Nutrition scientist and accomplished power athlete.
Episode: #380 ‒ The seed oil debate: are they uniquely harmful relative to other dietary fats? | Layne Norton, Ph.D.
Abbie Smith-Ryan
Associate Chair for Research in the Department of Exercise and Sports Science, Director of the Applied Physiology Lab, and Co-Director of the Human Performance Center at the University of North Carolina at Chapel Hill.
University of North Carolina at Chapel Hill
Episode: #378 ‒ Women's health and performance: how training, nutrition, and hormones interact across life stages | Abbie Smith-Ryan, Ph.D.
Dom D'Agostino
Neuroscientist and professor at the forefront of metabolic therapies including ketogenic strategies.
University of South Florida
Episode: #375 - Ketogenic diet, ketosis & hyperbaric oxygen: metabolic therapies for weight loss, cognition, Alzheimer's & more | Dom D'Agostino, Ph.D.
Carole Hooven
Human evolutionary biologist, former Harvard lecturer, and author of 'T: The Story of Testosterone'
American Enterprise Institute
Episode: #374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

Host

Peter Attia
Host of the long-running, data-driven health and longevity show; widely quoted for deep dives into medical science and practical health optimization.

Reviews

4.2 out of 5 stars from 18.7k ratings
  • BFFs with Epstein. In the most generous interpretation, his complete lack of character judgement means nothing he says should be trusted. More likely, he's a terrible person.

    Podcast Addict
    1
    Benjamus
    10 days ago
  • Sociopathy Should be Studied

    What we learned in the Epstein communications and the subsequent revelations regarding Attia tells us to stay as far away from his businesses and content as possible.

    Apple Podcasts
    1
    Mclovstein
    United Statesa month ago
  • We know you’re smart

    Peter spends too much time trying to show how smart he is it takes forever to get to the specifics of what is needed to do to benefit from the info.

    Apple Podcasts
    3
    TLR1sr
    United States2 months ago
  • Don’t support a man tied to men who assault women

    After reading the article about his ties to Epstein, this man lost all credit in my eyes. Absolutely disgusting.

    Apple Podcasts
    1
    Lspann
    United States2 months ago
  • Lost my respect

    Good health information, but hearing about his love of Epstein has really soured me on his podcast. I know nobody is perfect, and we all have some less-than-savory aspects of our personalities, but I find it hard to listen to him anymore.

    Apple Podcasts
    2
    LouisTLouis
    United States2 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Some critics say episodes can be dense and time-consuming without specifics.
Listeners praise evidence-based insights and practical health guidance.
A segment of feedback highlights concerns about host associations with Epstein coverage.
Fans appreciate the rigor and clarity in explaining complex medical topics.
Many find the content high-quality, data-driven, and life-changing for health decisions.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

#403 ‒ Peptides: separating scientific promise from marketing hype
Q: What makes BPC-157 a cautionary example in this space?
BPC-157 lacks a clear mechanism, has no solid human randomized trials, shows questionable safety data, and has been promoted across many indications without convincing evidence, illustrating why strong evidence and transparency matter.
#403 ‒ Peptides: separating scientific promise from marketing hype
Q: How should a patient think about a peptide with plausible biology but limited human data?
Calibrate enthusiasm to the strength of evidence; acknowledge biology may be real but demand rigorous human data before expecting meaningful outcomes, especially for off-label or wellness goals.
#403 ‒ Peptides: separating scientific promise from marketing hype
Q: So Peter, define what peptides are and what questions matter when evaluating them.
Peptides are short chains of amino acids, and evaluating them requires a framework: establish a plausible mechanism, confirm meaningful human evidence, understand safety and pharmacokinetics, weigh the risk against the benefit for a specific patient, and consider if a better-characterized approach exists.
#395 - Brain lipidology: understanding APOE, cholesterol homeostasis, Alzheimer's disease risk, and the effects of lipid-lowering therapies on brain health | Tom Dayspring, M.D.
Q: Do statins affect the brain, and should their use be tailored by lipid- or APOE-status?
Statins can cross the blood-brain barrier to varying degrees; in steady state, they may reduce brain cholesterol synthesis with potential protective effects against amyloid pathology, but overt suppression could theoretically impact neuronal membranes. Overall data show neutral to potential modest benefit for cognition/AD biomarkers, with no clear evidence of harm, though patient-specific factors (like APOE4 status) may guide dosing and choice.

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Frequently Asked Questions About The Peter Attia Drive

What is The Peter Attia Drive about and what kind of topics does it cover?

The show consistently explores health, longevity, and medical science through a rigorous, data-driven lens. Episodes thread together cutting-edge biomedical topics—ranging from basic science discoveries and biomarker-guided care to practical strategies for aging, sleep, cancer screening, and metabolic health—often featuring expert guests who illuminate complex mechanisms and real-world implications. A recurring strength is translating dense research into actionable guidance, with a strong emphasis on evaluating evidence, balancing risk and benefit, and understanding how lifestyle, diagnostics, and therapeutics interact over the long term. A notable standout is the hosting approach that blends deep scientific rigor with accessible storytelli... more

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Which podcasts are similar to The Peter Attia Drive?

These podcasts share a similar audience with The Peter Attia Drive:

1. Huberman Lab
2. The Dr. Gabrielle Lyon Show
3. The Dr. Hyman Show
4. Perform with Dr. Andy Galpin
5. Dhru Purohit Show

How many episodes of The Peter Attia Drive are there?

The Peter Attia Drive launched 8 years ago and published 453 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Peter Attia Drive?

Recent guests on The Peter Attia Drive include:

1. Linus Abrams
2. Jim Otvos
3. Gaia Devi
4. Renato Tomioka
5. Lisa Mosconi
6. Layne Norton
7. Abbie Smith-Ryan
8. Dom D'Agostino

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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