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The Peter Attia Drive

Peter Attia, MD
Metabolic Health
Nutrition
VO2 Max
Cardiovascular Disease
Alzheimer's Disease
Exercise
Longevity
Aging
Glp-1 Agonists
Mental Health
Body Composition
Obesity
Type 2 Diabetes
Cancer
Hair Loss
Exercise Physiology
Nutrition Science
Metabolism
Healthcare
Happiness

Expert insight on health, performance, longevity, critical thinking, and pursuing excellence. Dr. Peter Attia (Stanford/Hopkins/NIH-trained MD) talks with leaders in their fields.

PublishesWeeklyEpisodes447Founded8 years ago
Number of ListenersCategories
FitnessHealth & FitnessMedicine

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Gayatri Devi is a nationally recognized neurologist specializing in memory disorders, including Alzheimer's di... more

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In this "Ask Me Anything" (AMA) episode, Peter dives deep into the topic of muscle mass and strength, examinin... more

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In this "Ask Me Anything" (AMA) episode, Peter explores the effects of GLP-1 receptor agonists—including drugs... more

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Renato Tomioka is a leading expert in reproductive medicine and gynecologic surg... more

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Recent Guests

Renato Tomioka
Dr. Renato Tomioka, reproductive medicine and gynecologic surgery expert
Medical practice (Brazil)
Episode: #397 ‒ Endometriosis and adenomyosis: diagnosis, fertility, reproductive aging, and emerging treatments | Renato Tomioka, M.D., Ph.D.
Lisa Mosconi
Neuroscientist, Neuroimager, and Director of the Women's Brain Initiative at Weill Cornell Medicine
Weill Cornell Medicine
Episode: #381 ‒ Alzheimer's disease in women: how hormonal transitions impact the female brain, the role of HRT, genetics, and lifestyle on risk, and emerging diagnostics and therapies | Lisa Mosconi, Ph.D.
Layne Norton
Nutrition scientist and accomplished power athlete.
Episode: #380 ‒ The seed oil debate: are they uniquely harmful relative to other dietary fats? | Layne Norton, Ph.D.
Abbie Smith-Ryan
Associate Chair for Research in the Department of Exercise and Sports Science, Director of the Applied Physiology Lab, and Co-Director of the Human Performance Center at the University of North Carolina at Chapel Hill.
University of North Carolina at Chapel Hill
Episode: #378 ‒ Women's health and performance: how training, nutrition, and hormones interact across life stages | Abbie Smith-Ryan, Ph.D.
Dom D'Agostino
Neuroscientist and professor at the forefront of metabolic therapies including ketogenic strategies.
University of South Florida
Episode: #375 - Ketogenic diet, ketosis & hyperbaric oxygen: metabolic therapies for weight loss, cognition, Alzheimer's & more | Dom D'Agostino, Ph.D.
Carole Hooven
Human evolutionary biologist, former Harvard lecturer, and author of 'T: The Story of Testosterone'
American Enterprise Institute
Episode: #374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.
Walter Green
Philanthropist, mentor, and author of 'This Is the Moment'.
Founder of the Say It Now movement
Episode: The impact of gratitude, serving others, embracing mortality, and living intentionally | Walter Green (#288 rebroadcast)
Antonio Bianco, M.D., Ph.D.
Physician scientist and internationally recognized expert in thyroid physiology and metabolism
John Sealy School of Medicine, UTMB
Episode: #373 – Thyroid function and hypothyroidism: why current diagnosis and treatment fall short for many, and how new approaches are transforming care | Antonio Bianco, M.D., Ph.D.
Rhonda Patrick
Scientist, health educator, and host of FoundMyFitness podcast
FoundMyFitness
Episode: #369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Host

Peter Attia
Host of the show, physician and longevity expert, engaging leaders in health science and clinical practice.

Reviews

4.2 out of 5 stars from 18.5k ratings
  • Sociopathy Should be Studied

    What we learned in the Epstein communications and the subsequent revelations regarding Attia tells us to stay as far away from his businesses and content as possible.

    Apple Podcasts
    1
    Mclovstein
    United States5 days ago
  • We know you’re smart

    Peter spends too much time trying to show how smart he is it takes forever to get to the specifics of what is needed to do to benefit from the info.

    Apple Podcasts
    3
    TLR1sr
    United States18 days ago
  • Don’t support a man tied to men who assault women

    After reading the article about his ties to Epstein, this man lost all credit in my eyes. Absolutely disgusting.

    Apple Podcasts
    1
    Lspann
    United States25 days ago
  • Lost my respect

    Good health information, but hearing about his love of Epstein has really soured me on his podcast. I know nobody is perfect, and we all have some less-than-savory aspects of our personalities, but I find it hard to listen to him anymore.

    Apple Podcasts
    2
    LouisTLouis
    United Statesa month ago
  • Please vet who you support

    As women, especially, we need to be careful who we give our support to and be especially wary when it comes to male influencers/podcasters/doctors/etc. Peter Attia is a sick individual, and so is anyone who continues supporting his podcast after knowing his involvement with Epstein

    Apple Podcasts
    1
    SRH0709
    United Statesa month ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Guest line-up is top-tier with evidence-based discussions.
Shows strong medical rigor and practical health strategies.
Listener concerns center on ethics and credibility amid controversies around the host.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

#395 - Brain lipidology: understanding APOE, cholesterol homeostasis, Alzheimer's disease risk, and the effects of lipid-lowering therapies on brain health | Tom Dayspring, M.D.
Q: Do statins affect the brain, and should their use be tailored by lipid- or APOE-status?
Statins can cross the blood-brain barrier to varying degrees; in steady state, they may reduce brain cholesterol synthesis with potential protective effects against amyloid pathology, but overt suppression could theoretically impact neuronal membranes. Overall data show neutral to potential modest benefit for cognition/AD biomarkers, with no clear evidence of harm, though patient-specific factors (like APOE4 status) may guide dosing and choice.
#395 - Brain lipidology: understanding APOE, cholesterol homeostasis, Alzheimer's disease risk, and the effects of lipid-lowering therapies on brain health | Tom Dayspring, M.D.
Q: What is the relationship between brain cholesterol movement and amyloid/tau pathology?
Cholesterol accumulation in neuron membranes can influence the processing of amyloid precursor protein via secretases, favoring amyloid beta-42 production when cholesterol is high; conversely, appropriate cholesterol balance supports healthier membrane signaling, potentially reducing amyloid and tau toxicity. APOE genotype modulates this transport and membrane composition, linking lipid homeostasis to AD risk.
#393 ‒ AMA #85: A guide to medications and supplements: determining what to take, what to skip, and how to know if they're working for you
Q: And based on that classification, does it change the evidence threshold you like to see and how much risk you're willing to tolerate?
After defining the problem and the intervention's job, the required evidence and acceptable risk vary: disease treatment requires strong outcomes, symptom relief focuses on perceived benefit with safety caveats, risk reduction needs validated surrogates or hard outcomes, and optimization should be approached with skepticism due to smaller effects and higher uncertainty.

Audience Metrics

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Frequently Asked Questions About The Peter Attia Drive

What is The Peter Attia Drive about and what kind of topics does it cover?

Listeners tune in for deep dives at the intersection of health, longevity, and performance, guided by a medically trained host who brings in leading experts across nutrition, neuroscience, cardiology, and preventive medicine. Episodes commonly explore evidence-based frameworks, actionable health strategies, and the nuances of emerging therapies, often with a mix of clinical insight and real-world applicability. A distinctive aspect is the guest diversity—from neuroscientists and nutrition researchers to exercise physiologists and hormone scientists—paired with a consistent emphasis on critical thinking and rigorous science. This combination makes it valuable for professionals seeking credible, high-signal conversations and for sponsors look... more

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Which podcasts are similar to The Peter Attia Drive?

These podcasts share a similar audience with The Peter Attia Drive:

1. Huberman Lab
2. The Dr. Gabrielle Lyon Show
3. The Dr. Hyman Show
4. The Rich Roll Podcast
5. Dhru Purohit Show

How many episodes of The Peter Attia Drive are there?

The Peter Attia Drive launched 8 years ago and published 447 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Peter Attia Drive?

Recent guests on The Peter Attia Drive include:

1. Renato Tomioka
2. Lisa Mosconi
3. Layne Norton
4. Abbie Smith-Ryan
5. Dom D'Agostino
6. Carole Hooven
7. Walter Green
8. Antonio Bianco, M.D., Ph.D.

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