
Optispan is a vision for what health should be. The typical person gives up 10-20 years of quality life in exchange for disability, frailty, and early death. We call this "the lost decade". Time that should be spent with loved ones doing the activities you enjoy are instead spent suffering from multiple diseases and taking a cabinet full of medications that probably do as much harm as good. We bel... more
| Publishes | Twice weekly | Episodes | 168 | Founded | 2 years ago |
|---|---|---|---|---|---|
| Number of Listeners | Category | Science | |||

What if you had more control over your brain's future than you think? Dr. Tommy Wood, neuroscientist, Associate Professor of Pediatrics at the University of Washington, and head of science for motorsport at Hintsa Performance, joins Dr. Matt Kaeberle... more
Dr. Matt Kaeberlein and Clinical Director Dr. Nicki Byrne tackle your most pressing supplement questions in this AMA episode, cutting through the hype to give you science-backed answers you can actually use. From CoQ10 and statins to sulforaphane inf... more
The Galleri multi-cancer detection test made headlines when its landmark NHS trial failed to meet its primary endpoint, sending Grail's stock down nearly 50%. But does that mean Galleri is useless? Not exactly.
In this episode, Dr. Matt Kaeberlein ... more
What if menopause is one of the most important longevity events in human biology, and we've been ignoring it?
Dr. Matt Kaeberlein sits down with Dr. Jennifer Pearlman, founder of PearlMD and pioneer in female-centric longevity medicine, to unpack wh... more
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So knowledgeable. We saw him speak live and have been big fans of his work. He definitely cuts through the noise and is truly doing ground breaking research in the longevity space, without a lot of the fluff quick fix advice that has muddied the field.
I used to like listening to Matt and his very science informed opinions and would caveat his ‘takes’ vs ‘research baked’. But the most recent episode on cognitive improvements was nothing more than n=1 case study and what seemed to be poorly educated in the space guests opinions.
Dr Seager stated that for MD’s, knowledge ceases once we finish medical school. There was no pushback from Matt.
I’ve heard ridiculous comments from guests, but that one tops the list.
I’ve been a physician for 34 years and like every physician I have ever known, we obviously know that medical school is simply a springboard towards the goal for knowledge.
Physicians read scientific, peer-reviewed journals, we have journal club to discuss recent articles, we attend scientific meetings, we are ... more
Great information clearly delivered. I wish you were running the NHS in the UK or other equivalents around the world. Maybe with Peter Attia as well. Thank you Matt
Matt is the best. I have been taking rapamycin for 4 years and love his passion for the topic. He's an honest and trustworthy source for longevity news and information.
Key themes from listener reviews, highlighting what works and what could be improved about the show.
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Apple Podcasts | #169 |
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The show centers on evidence-based longevity, healthspan, and practical biology-driven wellness. Across episodes, listeners encounter deep dives into biomarkers, pharmacology, and dietary science, alongside critical reviews of trends like peptides, aging clocks, and hormone therapies. The hosts emphasize data-driven decisions, cautious use of supplements, and holistic prevention over reactive disease management, often featuring clinicians and researchers who challenge conventional medical norms. A standout is the blend of personal health journeys with rigorous science, plus candid conversations about the risks and realities of emerging therapies and wellness fads, making it a strong fit for listeners who value rigor and long-term health str... more
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These podcasts share a similar audience with The Optispan Podcast:
1. Longevity by Design
2. STEM-Talk
3. The Peter Attia Drive
4. The Metabolic Link
5. Huberman Lab
The Optispan Podcast launched 2 years ago and published 168 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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Recent guests on The Optispan Podcast include:
1. Jennifer Pearlman
2. Nicki Byrne
3. Kim Brockenbrough
4. Carlos Pinto
5. Dr. Ben Blue
6. Brad Stanfield
7. Alexandru Ardélion
8. Jan Hennigs
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