The Melanie Avalon Biohacking Podcast

Melanie Avalon

Mental Health

Nutrition

Biohacking

Gut Microbiome

Magnesium

Personal Growth

Alzheimer's Disease

Trauma

Vitamin D

Gut Health

Fasting

Intermittent Fasting

Emotional Intelligence

Health

Happiness

Longevity Science

Electromagnetic Fields

EMF Protection

Ayurveda

Hormone Optimization

Join best-selling author and actress Melanie Avalon as she interviews today's leading health and wellness experts, going beyond the fads to bring you all the biohacking tips, tricks, and techniques to effortlessly upgrade your body, brain, and life. Because why not live awesome? You got this! Theme Music by Narek Mirzaei, Artwork by Barbara McGregor

834 ratings

Publishes	Weekly	Episodes	370	Founded	7 years ago
Number of Listeners		Categories	NutritionAlternative HealthHealth & Fitness

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Latest Episodes

#367 - Dr. Tommy Wood: The Stimulated Mind, Preventing Dementia, The Meaning Of Intelligence, Boosting Memory, Enhancing Focus, Multitasking Cost, AI’s Effects On The Brain, Alcohol, Caffeine & Nicotine, And More!

TRANSCRIPT AND FULL SHOW NOTES:

melanieavalon.com/stimulatedmind

Book: The Stimulated Mind: Future-Proof Your Brain from Dementia and Stay Sharp at Any Age

SPONSORS AND DISCOUNTS:

AVALONX: Melanie made AvalonX to be her ideal supplements! They c... more

14 Aug 2026 • 1 hr 32 min • Most popular

#366 - Dr. Michael Greger: How Not To Die Documentary, Plant Food Activism, Removing Animal Products, Why We Lost Vitamin C, Reversing Clogged Arteries, GLP-1 Agonists, Fraud In Scientific Research, Food Change For Socioeconomic Status, Paleo Problems, And More!

TRANSCRIPT AND FULL SHOW NOTES:

melanieavalon.com/hownottodie

Documentary: watch.unchainedtv.com/videos/how-not-to-die-2

SPONSORS AND DISCOUNTS:

LMNT: LMNT is a zero-sugar electrolyte drink that supports hydration, energy, brain function... more

7 Aug 2026 • 30 min

#365 - Shalin Shah: Oral Testosterone Therapy, Kyzatrex's FDA Approval, Hormone Replacement Therapy Myths, Conventional Vs. Ideal Ranges, Dosing & Timing, Low Testosterone Symptoms, Myths & Misconceptions, Optimizing SHBG, Feedback Loop Concerns, Testosterone For Women, GLP-1 Agonists + Testosterone, And More!

TRANSCRIPT AND FULL SHOW NOTES:

melanieavalon.com/testosterone

SPONSORS AND DISCOUNTS:

AVALONX: Melanie made AvalonX to be her ideal supplements! They come in glass bottles, are free of toxic fillers and common allergens, screened for heavy metal... more

31 Jul 2026 • 1 hr 3 min

#364 - Will Bulsiewicz: Plant Powered Plus, Supporting Your Gut Microbiome, Counting Plants Vs. Fiber, Postbiotic SCFA Benefits, LPS: Friend Or Foe?, The Mediterranean Diet, Sleep & Inflammation, Curcumin Vs. Turmeric, Boosting Serotonin Release, And More!

Get 10% off your order, and subscribe to save up to 35% on your first subscription order with code MelanieAvalon at 38tera.com

TRANSCRIPT AND FULL SHOW NOTES:

melanieavalon.com/plantpowered

Book: Plant Powered Plus: Activate the Power of Y... more

24 Jul 2026 • 1 hr 26 min

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Recent Guests

Tommy Wood

Neuroscientist, author of The Stimulated Mind

University of Washington, Neuroscience Lab

Episode: #367 - Dr. Tommy Wood: The Stimulated Mind, Preventing Dementia, The Meaning Of Intelligence, Boosting Memory, Enhancing Focus, Multitasking Cost, AI’s Effects On The Brain, Alcohol, Caffeine & Nicotine, And More!

Shalin Shah

CEO of Marius Pharmaceuticals, developer of Kyzatrex

Marius Pharmaceuticals

Episode: #365 - Shalin Shah: Oral Testosterone Therapy, Kyzatrex's FDA Approval, Hormone Replacement Therapy Myths, Conventional Vs. Ideal Ranges, Dosing & Timing, Low Testosterone Symptoms, Myths & Misconceptions, Optimizing SHBG, Feedback Loop Concerns, Testosterone For Women, GLP-1 Agonists + Testosterone, And More!

Will Bulsiewicz

Gastroenterologist, NYT bestselling author of Fiber Fueled and Plant Powered Plus

Chicago-based medical practice, author

Episode: #364 - Will Bulsiewicz: Plant Powered Plus, Supporting Your Gut Microbiome, Counting Plants Vs. Fiber, Postbiotic SCFA Benefits, LPS: Friend Or Foe?, The Mediterranean Diet, Sleep & Inflammation, Curcumin Vs. Turmeric, Boosting Serotonin Release, And More!

Frank Yosa

Founder of Hard Ketones and Ketone Aid

Hard Ketones / Ketone Aid

Episode: #362 - Frank Llosa: Exogenous Ketone Benefits, Ketone Supplement Myths, Hard Ketones: Alcohol-Free Buzz, Boosting Cognition & Athletic Performance, Becoming Keto Adapted, Amplifying Caffeine, Measuring Ketones, Intermittent Fasting Tools, And More!

Dr. Jo Brown

Head of Human Performance at Paracem; global authority on nervous system modulation, HRV intelligence, readiness and recovery

Paracem / NeuroPod

Episode: #361 - Dr. Jo Brown: Nuropod, Vagus Nerve Stimulation, Interpreting HRV, Becoming Your Authentic Self, Supporting Stress Relief, Optimum Physical Performance, Parasympathetic & Sympathetic Nervous Systems, How To Actually Recover, Optimum Vagal Tone, And More!

Dr. Michelle Jorgensen

Holistic dentist and author of Living Well with Dr. Michelle

Total Care Dental, Utah

Episode: #360 - Dr. Michelle Jorgensen: Supporting Cellular Energy, The Truth About Fluoride, Cosmetic Dentistry, Living Seasonally, Mercury Fillings & Chelation, Holistic Dentistry, Epigenetics, Modern Approaches To Traditional Medicine, And More!

Michael Biamonte

Doctor and Candida expert, author of The Candida Chronicles

Health Truth / Candida Chronicles

Episode: #359 - Dr. Michael Biamonte: The Candida Chronicles, Parasites & Heavy Metals, Candida Diet Myths, Multiphase Antifungal Protocol, Antifungal Rotation, Supplement Vs. Pharmaceutical Efficacy, Bowel Cleanses, Vitamins That Feed Candida, Antioxidant Problems, Vaginal Yeast Infections, Saccharomyces Boulardii, And More!

Charis Chambers

Chief Medical Officer, Clue app; board-certified OBGYN

Clue

Episode: #358 - Charis Chambers: The Clue App, Menstrual Cycle Myths, Period And Puberty Parenting Revolution, Cycle Tracking, Data Privacy, Cycle Syncing Problems, Painful Periods, Ovulation And Longevity, Freezing Eggs, Birth Control Stigmas, And More!

Jill Robin Payne

Licensed professional counselor supervisor and author of Bempathy

Bempathy (book)

Episode: #357 - Jill Robin Payne: Banter + Empathy Benefits, The Problems With "Boundaries", The Power of Language, Complimenting People, Navigating Virtual Reality, Dynamic Watchfulness, The Map Of Reflection, The Anxiety Bubble, Combatting Cognitive Bias, And More!

Host

Melanie Avalon

Host of The Melanie Avalon Biohacking Podcast

Reviews

4.6 out of 5 stars from 834 ratings

Peptide’s with Jay
Wow Melanie! That was one of the best or maybe the best podcast I’ve ever listened to so much good information from Jay Campbell and your questions are so thoughtful and provocative! I am going to listen to it again, and I’ve shared it with several people! Thanks for bringing a cute girl voice into the biohacking podcast arena!!
Apple Podcasts
5
lakelady16
United Statesa year ago
Episode #317 with Dr. Anna Cabeca
Hey there, love the podcast. Love both of you.
In this podcast questions came in from a Canadian listener.
In your podcast today it was indicated by the Canadian listener that Dutch Testing is not available in Canada. I live in Canada and I have had Dutch test done through my Naturopath Clinic and know that it is readily available in Canada.
Another listener mentions that she cannot get a practitioner that can or will prescribe testosterone for her. Well again, I have been using compounded... more
Apple Podcasts
5
Sunshine Kimmy
Canadaa year ago
Love it. Can we be friends ?
I love this podcast and the intermittent fasting podcast too with Barry.
This latest episode got me in the feels , and now I'm buying Karenas book. Melanie , you make me ugly laugh while I'm driving. Head thrown back , mouth open ,straight up guffaw. I must look insane
I am a visiting nurse and I binge listen to your episodes between clients, and I really get your personality and I love how humble and real you are. Good job. K bye.
Apple Podcasts
5
Switch McBitch
Canadaa year ago
Most entertaining and informative biohacking podcaster!
I have been following this podcast for 2-3 years and have learned soooo much valuable information. Melanie has a wide range of guests and is well prepared for each one. Some episodes are interesting, some intriguing, some mind blowing and some have been life changing!
Apple Podcasts
5
Doja314
United Statesa year ago
Essential Oils as a biohack
Dr Zielinski is very passionate and pragmatic about essential oils and the usage. I learned a lot about the sense of smell and the importance of essential oils in our everyday lives. Melanie asked great probing questions and shared her personal experience as well!
Apple Podcasts
5
NC Waterfalls Enthusiast
United Statesa year ago

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Listeners praise the host's preparation and the breadth of guests.

Many reviews highlight actionable insights and lasting value from episodes.

Thoughtful, well-researched questions and deep dives make episodes feel premium and credible.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts	#72	United States/Health & Fitness/Nutrition
Apple Podcasts	#115	Canada/Health & Fitness/Nutrition
Apple Podcasts	#101	Australia/Health & Fitness/Nutrition
Apple Podcasts	#202	France/Health & Fitness/Nutrition
Apple Podcasts	#10	South Africa/Health & Fitness/Nutrition
Apple Podcasts	#49	New Zealand/Health & Fitness/Nutrition

Talking Points

Recent interactions between the hosts and their guests.

#366 - Dr. Michael Greger: How Not To Die Documentary, Plant Food Activism, Removing Animal Products, Why We Lost Vitamin C, Reversing Clogged Arteries, GLP-1 Agonists, Fraud In Scientific Research, Food Change For Socioeconomic Status, Paleo Problems, And More!

Q: What are your thoughts on the documentary's treatment of nutrition science and the issue of research fraud?

He emphasizes the need for skepticism toward published data, highlights fraud and manipulation in research, and argues that viewers should rely on the best available evidence while pushing for openness and better standards in scientific publishing.

Q: What was it like transforming your book into a documentary format?

Greger explains that the documentary evolved from his presentation material, with a director and crew turning the talk into a film that includes interludes with other experts and additional footage, all aimed at broadening reach beyond books and online content.

#365 - Shalin Shah: Oral Testosterone Therapy, Kyzatrex's FDA Approval, Hormone Replacement Therapy Myths, Conventional Vs. Ideal Ranges, Dosing & Timing, Low Testosterone Symptoms, Myths & Misconceptions, Optimizing SHBG, Feedback Loop Concerns, Testosterone For Women, GLP-1 Agonists + Testosterone, And More!

Q: What about testosterone therapy for women and the current FDA status?

There are currently no FDA-approved testosterone therapies for women; the company is pursuing a female development program and advocacy for FDA-approved options.

Q: When did Kyzatrex receive FDA approval and how long was the development process?

Kyzatrex was approved in July 2022 after roughly 13 years from initial development, with 10 years of R&D and about a year and a half for the FDA filing and review.

#363 - Ben Azadi: Keto Flex, Becoming Fat Vs. Keto-Adapted, Adapt, Fast, Phase, Flex, Measuring Ketones, The Great Seed Oil Debate, Carnivore Benefits, Raynaud's Syndrome, GLP-1 Agonists, Protein Importance, Fatty Acids In Cell Membranes, And More!

Q: So, what is the purpose of the four pillars and what is the order of adapting through them?

The four pillars progressively guide the body from fat adaptation to fasting, then to phasing out antinutrients with carnivore elements, and finally to a flexible keto approach that adapts to individual needs, with timing and sequencing chosen to minimize overwhelm and maximize long-term metabolic flexibility.

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Frequently Asked Questions About The Melanie Avalon Biohacking Podcast

What is The Melanie Avalon Biohacking Podcast about and what kind of topics does it cover?

Across recent episodes, the show consistently explores cutting-edge health and wellness topics through expert interviews. Guests range from neuroscientists and physicians to authors and entrepreneurs, with frequent focus on biohacking, longevity, nutrition, gut health, hormones, and performance optimization. The host asks thoughtful, evidence-oriented questions, often unpacking controversial or complex topics (like GLP-1 drugs, exogenous ketones, or hormone therapies) for practical takeaways. A notable strength is synthesizing research with real-world applications, personal stories, and actionable strategies, making it useful for listeners who want credible, deep-dive insights without buzzwords.

Unique appeal lies in bridging rigorous scie... more

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Which podcasts are similar to The Melanie Avalon Biohacking Podcast?

These podcasts share a similar audience with The Melanie Avalon Biohacking Podcast:

1. The Intermittent Fasting Podcast
2. Optimal Protein Podcast with Vanessa Spina
3. Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+
4. The Ben Azadi Show
5. The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health

How many episodes of The Melanie Avalon Biohacking Podcast are there?

The Melanie Avalon Biohacking Podcast launched 7 years ago and published 370 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Melanie Avalon Biohacking Podcast?

Recent guests on The Melanie Avalon Biohacking Podcast include:

1. Tommy Wood
2. Shalin Shah
3. Will Bulsiewicz
4. Frank Yosa
5. Dr. Jo Brown
6. Dr. Michelle Jorgensen
7. Michael Biamonte
8. Charis Chambers

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