The Melanie Avalon Biohacking Podcast

Melanie Avalon

Mental Health

Nutrition

Biohacking

Gut Microbiome

Alzheimer's Disease

Personal Growth

Magnesium

Trauma

Vitamin D

Gut Health

Fasting

Intermittent Fasting

Emotional Intelligence

Health

Happiness

Longevity Science

Electromagnetic Fields

EMF Protection

Ayurveda

Hormone Optimization

Join best-selling author and actress Melanie Avalon as she interviews today's leading health and wellness experts, going beyond the fads to bring you all the biohacking tips, tricks, and techniques to effortlessly upgrade your body, brain, and life. Because why not live awesome? You got this! Theme Music by Narek Mirzaei, Artwork by Barbara McGregor

834 ratings

Publishes	Weekly	Episodes	382	Founded	7 years ago
Number of Listeners		Categories	NutritionAlternative HealthHealth & Fitness

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Guests Host Reviews Charts Talking Points

Latest Episodes

#379 - Jeff Zwiefel: The Future Of Longevity, Life Time Gyms Success, Personalized Supplements, The Most Important Health Biomarkers, Testing Your Mitochondria, Interpreting Lab Data, Healthspan Vs. Lifespan, Who To Trust, And More!

TRANSCRIPT AND FULL SHOW NOTES:

melanieavalon.com/jeffzwiefel

SPONSORS AND DISCOUNTS:

AVALONX: Melanie made AvalonX to be her ideal supplements! They come in glass bottles, are free of toxic fillers and common allergens, screened for heavy metals... more

6 Nov 2026 • 1 hr 11 min • Most popular

#378 - Jason Fung: The Hunger Code, Rethinking the Body Fat Equation, The Three Types of Hunger, Calories vs. Hormones, Skipping Breakfast, Food Amnesia, Food Addiction, Why You Can't Lose Weight, And More!

TRANSCRIPT AND FULL SHOW NOTES:

melanieavalon.com/hungercode

Book: a.co/d/07WezKPQ

SPONSORS AND DISCOUNTS:

AVALONX: Melanie made AvalonX to be her ideal supplements! They come in glass bottles, are free of toxic fillers and common aller... more

30 Oct 2026 • 1 hr 24 min • Popular

#377 - Austin Perlmutter: Brain Wash, Polyphenols & Aging, Sickness & Social Withdrawal, Measuring Immune Inflammation, The Evolutionary Purpose Of Anxiety & Depression, Epigenetic Clocks, Brain Inflammation Effects, Social Media Problems, Tartary Buckwheat Benefits, And More!

TRANSCRIPT AND FULL SHOW NOTES:

melanieavalon.com/austinperlmutter

Book: amzn.to/4oF0nQA

SPONSORS AND DISCOUNTS:

AVALONX: Melanie made AvalonX to be her ideal supplements! They come in glass bottles, are free of toxic fillers and common ... more

23 Oct 2026 • 1 hr 24 min

#376 - Ashley Koff: Your Best Shot, GLP-1 Agonist Benefits, Your Weight Health Hormones, GLP-1, GIP, CCK & PYY, Reducing Food Reward, Regulating Insulin, GLP-1 Judgment Bias, “Microdosing”, Body Weight Set Points, When & How to Come Off Ozempic, Why Food Should Be Delicious, And More!

TRANSCRIPT AND FULL SHOW NOTES:

melanieavalon.com/bestshot

Book: amzn.to/3QrB5bZ

SPONSORS AND DISCOUNTS:

AVALONX: Melanie made AvalonX to be her ideal supplements! They come in glass bottles, are free of toxic fillers and common allergen... more

16 Oct 2026 • 1 hr 29 min

Key Facts

Accepts Guests

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Number of Listeners

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Similar Podcasts

People also subscribe to these shows.

The Intermittent Fasting PodcastMelanie Avalon, Barry Conrad

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LONGEVITY with Nathalie NiddamNathalie Niddam

The Hormone Solution | Menopause, Perimenopause, & Women's Midlife HealthKaren Martel: Certified Hormone Specialist

Recent Guests

Jason Fung

Author of The Hunger Code, The Obesity Code and The Complete Guide to Fasting.

The Fasting Method

Episode: #378 - Jason Fung: The Hunger Code, Rethinking the Body Fat Equation, The Three Types of Hunger, Calories vs. Hormones, Skipping Breakfast, Food Amnesia, Food Addiction, Why You Can't Lose Weight, And More!

Austin Perlmutter

Board-certified internal medicine physician, researcher, educator and New York Times bestselling author.

Big Bold Health

Episode: #377 - Austin Perlmutter: Brain Wash, Polyphenols & Aging, Sickness & Social Withdrawal, Measuring Immune Inflammation, The Evolutionary Purpose Of Anxiety & Depression, Epigenetic Clocks, Brain Inflammation Effects, Social Media Problems, Tartary Buckwheat Benefits, And More!

Ashley Koff

Registered dietitian, founder of The Better Nutrition Program and nutrition course director for UC Irvine

The Better Nutrition Program

Episode: #376 - Ashley Koff: Your Best Shot, GLP-1 Agonist Benefits, Your Weight Health Hormones, GLP-1, GIP, CCK & PYY, Reducing Food Reward, Regulating Insulin, GLP-1 Judgment Bias, “Microdosing”, Body Weight Set Points, When & How to Come Off Ozempic, Why Food Should Be Delicious, And More!

Dr. Jolene Brighten

Author of ADHD in Women, Is This Normal, Beyond the Pill

Brighten Wellness / author

Episode: #375 - Dr. Jolene Brighten: ADHD & Women, The Neurodivergent Spectrum, Autism, ADHD & AuDHD, The 5 ADHD Types, Stimulant Medications, Perimenopause, Pills & Puberty, The Benefits of ADHD, Seeking Novelty & Kinky Sex, Dopamine, Estrogen, Progesterone & Testosterone, Smart HRT, The Sour Shock, ADHD Superfoods, The Exhaustion of Societal Masking, Time Blindness, And More!

Deb Schachter

Author, clinician specializing in body image and eating disorders

Body Image Inside Out

Episode: #374 - Deb Schachter & Whitney Otto: Body Image Inside Out, Bad Body Image Moments, Is "Fat" A Feeling, Your Pedestal Person, Non-Judgemental Acceptance, Getting Rid Of Shame, Finding Your Alignment, Social Media & Image, The Benefits Of Clothes & Style, And More!

Whitney Otto

Author and leadership coach; US world rowing champion and Olympic contender

Body Image Inside Out

Scott Hutcheson

Author of Biohacking Leadership; Professor at Purdue University

Purdue University

Episode: #373 - Scott Hutcheson: Biohacking Leadership, The Three Key Leadership Traits, Theatrical Biomechanics, Body Language & Micro-Expressions, Emotional Contagion, Female Leadership Hurdles, Optimizing Communication, Outer And Inner Alignment, The Magic Of Storytelling, And More!

Dr. Zaldy Tan

Director of the Memory and Healthy Aging Program at Cedars-Sinai; Harvard-trained neurologist; professor

Cedars-Sinai Medical Center; Harvard Medical School; UCLA

Episode: #372 - Zaldy Tan: What To Remember When Forgetting, Normal Vs. Abnormal Memory Loss, The Stages Of Dementia, Supporting Loved Ones With Cognitive Decline, How To Diagnose Alzheimer’s, Partners And Intimacy, Lifestyle Vs. Genetics, Telling White Lies, And More!

Elisabeth Mckay

Author of Your Brain is a Filthy Liar; developer of Break Method

predictivemind.io Break Method

Episode: #371 - Elisabeth Mckay: Abandonment And Rejection, The Root Cause Of Your Problems, Perception Problems, Defining Objective Reality, Borderline Personality Disorder, Finding Your Baseline, Problems With Therapy, Nurture Vs. Nature, Healing Vs. Truth, Raising Children, And More!

Host

Melanie Avalon

Best-selling author and actress focused on health, nutrition and biohacking.

Reviews

4.6 out of 5 stars from 834 ratings

An absolute delight to listen to!
I learn so much from Melanie Avalon’s guests, but it’s Melanie’s own infectious enthusiasm and curiosity that will keep you listening!
Apple Podcasts
5
jh4593
United States3 months ago
Peptide’s with Jay
Wow Melanie! That was one of the best or maybe the best podcast I’ve ever listened to so much good information from Jay Campbell and your questions are so thoughtful and provocative! I am going to listen to it again, and I’ve shared it with several people! Thanks for bringing a cute girl voice into the biohacking podcast arena!!
Apple Podcasts
5
lakelady16
United Statesa year ago
Episode #317 with Dr. Anna Cabeca
Hey there, love the podcast. Love both of you.
In this podcast questions came in from a Canadian listener.
In your podcast today it was indicated by the Canadian listener that Dutch Testing is not available in Canada. I live in Canada and I have had Dutch test done through my Naturopath Clinic and know that it is readily available in Canada.
Another listener mentions that she cannot get a practitioner that can or will prescribe testosterone for her. Well again, I have been using compounded... more
Apple Podcasts
5
Sunshine Kimmy
Canadaa year ago
Love it. Can we be friends ?
I love this podcast and the intermittent fasting podcast too with Barry.
This latest episode got me in the feels , and now I'm buying Karenas book. Melanie , you make me ugly laugh while I'm driving. Head thrown back , mouth open ,straight up guffaw. I must look insane
I am a visiting nurse and I binge listen to your episodes between clients, and I really get your personality and I love how humble and real you are. Good job. K bye.
Apple Podcasts
5
Switch McBitch
Canadaa year ago
Most entertaining and informative biohacking podcaster!
I have been following this podcast for 2-3 years and have learned soooo much valuable information. Melanie has a wide range of guests and is well prepared for each one. Some episodes are interesting, some intriguing, some mind blowing and some have been life changing!
Apple Podcasts
5
Doja314
United Statesa year ago

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Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Some critical reviewers object to perceived product promotion and to the framing of weight, food and health.

Listeners often praise Melanie's preparation, thoughtful questions and engaging interview style.

Listeners describe the conversations as educational, motivating and relevant to personal health decisions.

Many value the range of expert guests, detailed explanations and practical ideas they can explore further.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts	#76	United States/Health & Fitness/Nutrition
Apple Podcasts	#75	Canada/Health & Fitness/Nutrition
Apple Podcasts	#240	United Kingdom/Health & Fitness/Nutrition
Apple Podcasts	#147	France/Health & Fitness/Nutrition
Apple Podcasts	#176	Australia/Health & Fitness/Nutrition
Apple Podcasts	#22	Philippines/Health & Fitness/Nutrition

Talking Points

Recent interactions between the hosts and their guests.

#378 - Jason Fung: The Hunger Code, Rethinking the Body Fat Equation, The Three Types of Hunger, Calories vs. Hormones, Skipping Breakfast, Food Amnesia, Food Addiction, Why You Can't Lose Weight, And More!

Q: Do you think that our culture changes as a whole and we actually stop eating these, or do you think it's too ingrained in the system?

Fung says cultural change is possible but slow. He points to tobacco advertising restrictions as a precedent and suggests limiting advertising of ultra-processed foods, especially to children.

Q: The calories versus the hunger, does it even matter at the end of the day? Where do you land?

Fung says calorie intake describes how weight change occurs, but hunger helps explain why people eat more. He argues that addressing the causes of hunger is more useful than simply restricting calories.

#377 - Austin Perlmutter: Brain Wash, Polyphenols & Aging, Sickness & Social Withdrawal, Measuring Immune Inflammation, The Evolutionary Purpose Of Anxiety & Depression, Epigenetic Clocks, Brain Inflammation Effects, Social Media Problems, Tartary Buckwheat Benefits, And More!

Q: What biomarkers can someone test to assess inflammation?

He names C-reactive protein, sedimentation rate and white blood cell counts, as well as cytokines and calculated indices such as the Systemic Immune Inflammation Index. He emphasizes that results need to be interpreted in context.

Q: How does loneliness and disconnection actually cause inflammation?

Perlmutter says loneliness can increase stress signals and is associated with inflammation. Social connection may offer protection through stress-mitigating effects and shared microbiomes that influence immune function.

#376 - Ashley Koff: Your Best Shot, GLP-1 Agonist Benefits, Your Weight Health Hormones, GLP-1, GIP, CCK & PYY, Reducing Food Reward, Regulating Insulin, GLP-1 Judgment Bias, “Microdosing”, Body Weight Set Points, When & How to Come Off Ozempic, Why Food Should Be Delicious, And More!

Q: If someone has insulin resistance and takes a GLP-1 agonist, does it simply add more insulin, or help existing insulin work better?

Koff says GLP-1 helps regulate the pacing of insulin release from pancreatic beta cells. In insulin resistance, this can reduce excessive insulin output while helping insulin function more effectively, though the broader metabolic system also matters.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About The Melanie Avalon Biohacking Podcast

What is The Melanie Avalon Biohacking Podcast about and what kind of topics does it cover?

Long-form interviews connect nutrition, metabolism, brain health, hormones, longevity and mental well-being with practical approaches to health and performance. Melanie Avalon guides conversations with clinicians, researchers, authors, dietitians, entrepreneurs and other specialists, often grounding questions in a guest's book, clinical work or research. Topics range from fasting and gut health to dementia prevention, weight-related medications, body image and athletic performance.

The format is curious and detailed, with room for scientific explanations, personal experience and discussion of how emerging ideas might apply in daily life. Its distinctive breadth brings conventional medical expertise together with biohacking, nutrition and w... more

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Which podcasts are similar to The Melanie Avalon Biohacking Podcast?

These podcasts share a similar audience with The Melanie Avalon Biohacking Podcast:

1. The Intermittent Fasting Podcast
2. Optimal Protein Podcast with Vanessa Spina
3. Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+
4. LONGEVITY with Nathalie Niddam
5. The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health

How many episodes of The Melanie Avalon Biohacking Podcast are there?

The Melanie Avalon Biohacking Podcast launched 7 years ago and published 382 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Melanie Avalon Biohacking Podcast?

Recent guests on The Melanie Avalon Biohacking Podcast include:

1. Jason Fung
2. Austin Perlmutter
3. Ashley Koff
4. Dr. Jolene Brighten
5. Deb Schachter
6. Whitney Otto
7. Scott Hutcheson
8. Dr. Zaldy Tan

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