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Optimal Protein Podcast with Vanessa Spina

Vanessa Spina
Fat Loss
Protein
Protein Intake
Nutrition
Metabolic Health
Resistance Training
Body Recomposition
Protein-Sparing Modified Fasting
Body Composition
Red Light Therapy
Muscle Protein Synthesis
Ketogenic Diet
Women's Health
Essential Amino Acids
Creatine
Aging
Protein Metabolism
Collagen
Protein Quality
Ketosis

Vanessa Spina is a Sports Nutrition Specialist, Best Selling author, creator of the innovative TONE device, as well as a sought after international speaker. On the Optimal Protein podcast, Vanessa shares how to get effortlessly lean and improve metabolic health and fitness with an optimal protein intake! Featuring interviews with world renowned and leading edge protein scientists & experts, author... more

PublishesTwice weeklyEpisodes541Founded9 years ago
Number of ListenersCategories
NutritionFitnessHealth & Fitness

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Latest Episodes

What really happens inside a woman's body during the menopause transition—and what can your hormones actually tell you?

In this episode of the Optimal Protein Podcast, Vanessa sits down with Madeline Wood Alexander, a researcher at the University o... more

In today's Friday recap, Vanessa breaks down seven fascinating takeaways from her conversation with Dr. Khashayar Farzam on testosterone in women, muscle preservation, hormones, and the science of fat loss.

Did you know that women typically have hi... more

Did you know women have more circulating testosterone than estrogen when measured in equivalent units? And could testosterone play an overlooked role in muscle growth, metabolism, and healthy aging?

In this episode, Vanessa is joined by Dr. Khashay... more

Can you use meal timing to lose body fat without sacrificing muscle—and does time-restricted eating actually change what is happening inside your fat cells?

In this Friday episode, Vanessa breaks down 8 of the biggest takeaways from her conversatio... more

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Recent Guests

Khashayar Farzam
Physician specializing in emergency and obesity medicine, founder of True North Metabolic, and clinical assistant professor
True North Metabolic
Episode: Women Have MORE Testosterone Than Estrogen?! Testosterone 101, Muscle & Menopause | Dr. Farzam
Satchin Panda
Circadian rhythm and time-restricted eating researcher
Episode: NEW STUDY: Dr. Satchin Panda on How IF/TRE Changes Your Fat Cells | Fat Loss, Muscle & Meal Timing
Milo Wolf
Researcher focused on resistance training, muscle growth, protein and exercise efficiency
Episode: New Study: Do You Really Need a Calorie Surplus to Build Muscle? | Dr. Milo Wolf
Amie Hornaman
Thyroid practitioner, author of The Thyroid Fix, and creator of T2-containing supplements
Fixer Formulas
Episode: T2 and Fat Burning: What the Thyroid Research Really Shows with Dr. Amie Hornaman
Dr. Mike T. Nelson
Dr. Mike Nelson, PhD in exercise physiology; researcher and clinician focusing on metabolic flexibility and sports nutrition
Independent researcher/Dr. Mike T. Nelson
Episode: Burning Fat vs. Losing Fat: Metabolic Flexibility Explained with Dr. Mike T. Nelson
Dr. Drew Gonzalez
Exercise and nutrition researcher directing the Occupational Performance and Nutrition Lab at Sam Houston State University
Sam Houston State University, Occupational Performance and Nutrition Lab
Episode: New Study on Creatine During Fat Loss and Body Recomposition: Dr. Drew Gonzalez
Lyle McDonald
Researcher and author focused on fat loss, body composition, and nutrition
Body Recomposition / Author
Episode: The Stubborn Fat Solution: How to Mobilize Lower-Body Fat with Lyle McDonald
Dr. Leigh Breen
Leading researcher in protein metabolism, resistance training, and skeletal muscle health
Leicester Diabetes Centre, University of Leicester
Episode: Are You Losing Muscle Instead of Fat? The Protein Strategy That Protects Lean Mass: Dr. Leigh Breen
Amanda Paluch
Associate Professor of Kinesiology, University of Massachusetts Amherst
University of Massachusetts Amherst
Episode: Do You Really Need 10,000 Steps to Lose Fat? The Science of Walking & Body Recomposition: Dr. Amanda Paluch

Host

Vanessa Spina
Host of The Optimal Protein Podcast, focused on protein-centered nutrition and metabolic health; author and speaker.

Reviews

4.6 out of 5 stars from 1.2k ratings
  • Good info, but she’s over valuing her information

    I like listening to her podcasts, but have to say, $180 for recipes is ridiculous. Tell me of another cookbook that costs that much! She’s pricing herself way too high for this information. Think of how many sales you would have and how many people you could help if you priced it at 20 or 30 bucks - more inline with a cookbook. She’s not very business savvy. She thinks she’s Ely Lilly…

    Apple Podcasts
    3
    tag1rn3455
    United States5 months ago
  • Misinformation

    Vanessa made an episode about the fasting and completely misconstrued the facts.

    Apple Podcasts
    1
    fdyjm
    Australia6 months ago
  • 10 min intro too long

    Takes forever to get to show!! Can’t always fast forward, adds and rambling for 10 min is too long.

    Apple Podcasts
    2
    Ruski 4.
    United States8 months ago
  • Good science

    Vanessa is smart and well studied making her recommendations backed by science. I do wish she would provide links to the studies mentioned (e.g., Lucy Burns study) in her recent episode

    Apple Podcasts
    4
    EileenofSeattle
    United Statesa year ago
  • Clear and Informative

    Vanessa has the best guests and information available for anyone following a keto or lower carb diet. She has such a talent for explaining studies in layman’s terms. I never write reviews but listening to her podcast Thai morning (PSMF) I just got so much out of it.

    Thanks, Vanessa 🙏🏻😎

    Apple Podcasts
    5
    Fitnessnut 62
    United Statesa year ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Listeners praise science-backed insights and clear explanations of studies.
Some feedback highlights balance of education and practical application, with occasional mentions of promotions.
Guests are high-caliber and topics stay focused on protein and metabolism.

Chart Rankings

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Talking Points

Recent interactions between the hosts and their guests.

Women Have MORE Testosterone Than Estrogen?! Testosterone 101, Muscle & Menopause | Dr. Farzam
Q: Do you think that women, in any situation, could benefit from taking testosterone in the form of hormone replacement therapy outside of the libido purview, as you put it?
Farzam says therapy may be appropriate on a case-by-case basis, but evidence and diagnostic cutoffs for women remain limited. He emphasizes safer, approved products and careful medical monitoring, and describes a time-limited trial as a possible option after shared decision-making.
Women Have MORE Testosterone Than Estrogen?! Testosterone 101, Muscle & Menopause | Dr. Farzam
Q: Why do you think testosterone right now is getting so much attention when it comes to women specifically?
Farzam points to growing public interest, regulatory attention, increased testosterone prescriptions for men, and emerging research, while noting the shortage of approved products for women.
NEW STUDY: Dr. Satchin Panda on How IF/TRE Changes Your Fat Cells | Fat Loss, Muscle & Meal Timing
Q: So for someone who is not doing these things, let's bring it all together for, let's say, a woman in her 50s who would like to lose some body fat, maybe also change the nature of how that body fat is behaving. Maintain their muscle and wants to have dinner with their family. How would you suggest to help organize her day, meals, protein, training, and sleep? What are the three biggest levers that she could pull to really optimize her day and overall health?
Panda recommends a consistent bedtime with a small time range, spending eight hours in bed, delaying breakfast for at least an hour after waking, getting daylight, exercising and keeping the eating window shorter. He also supports resistance training and a last meal about three hours before bedtime.
NEW STUDY: Dr. Satchin Panda on How IF/TRE Changes Your Fat Cells | Fat Loss, Muscle & Meal Timing
Q: Could you walk us through your new study? Tell us a little bit about who participated and what each group was asked to do, and then what happened to their body composition.
The study examined people with obesity who generally ate over a long daily window and guided them toward an eight- or ten-hour window. Analysis of fat-tissue samples found evidence of increased fat-breakdown pathways and lower inflammatory markers.
New Study: Do You Really Need a Calorie Surplus to Build Muscle? | Dr. Milo Wolf
Q: What is the minimum effective dose that you think people should be targeting over the course of a week in terms of just resistance training?
Wolf estimates that around four sets per muscle per week can build muscle at maintenance, while five to ten sets may be a better target during a calorie deficit. He says many people can manage this with two or three weekly sessions.

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Frequently Asked Questions About Optimal Protein Podcast

What is Optimal Protein Podcast about and what kind of topics does it cover?

The show centers on protein-forward nutrition, metabolic health, and evidence-based strategies for fat loss and lean mass preservation. Host Vanessa Spina interviews leading researchers, clinicians, and authors to translate complex studies into practical guidance on protein intake, fasting strategies, training, and hormonal health. Episodes often mix science with actionable tips, real-world applications, and sponsor integrations. Noteworthy is the consistent emphasis on high-protein approaches and the exploration of cutting-edge topics like PSMF, muscle maintenance during aging, and health optimization through lifestyle levers. Potential listeners include fitness enthusiasts, health professionals, and busy individuals seeking science-backed... more

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Optimal Protein Podcast launched 9 years ago and published 541 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Optimal Protein Podcast?

Recent guests on Optimal Protein Podcast include:

1. Khashayar Farzam
2. Satchin Panda
3. Milo Wolf
4. Amie Hornaman
5. Dr. Mike T. Nelson
6. Dr. Drew Gonzalez
7. Lyle McDonald
8. Dr. Leigh Breen

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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