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Behind the Genes

Genomics England
Genomics England
Genomics
Whole Genome Sequencing
Genetic Testing
Genomic Medicine
Clinical Genetics
Rare Conditions
100,000 Genomes Project
Genomic Testing
NHS
Genomic Healthcare
Cancer
Genetics
National Genomic Research Library
The Generation Study
Genetic Conditions
Rnu4-2 Gene
Neurodevelopmental Conditions
Generation Study
Genetic Counseling

At Genomics England, our vision is a world where everyone benefits from genomic healthcare.

From the latest research to the lived experiences of those affected by rare conditions and cancer, Behind the Genes brings you closer to the people behind the science.

Each month, we release a deep-dive episode, alongside our Genomics 101 series - short explainers designed to make complex terms in gene... more

PublishesTwice monthlyEpisodes100Founded5 years ago
Number of ListenersCategories
Social SciencesLife SciencesScience

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Artwork for Behind the Genes

Latest Episodes

A daily low dose of aspirin could significantly reduce the risk of bowel cancer in people with Lynch syndrome, an inherited condition that increases the likelihood of developing certain cancers.

In this episode, we explore the findings from the land... more

YouTube

In this explainer episode, we’ve asked Jamie Ellingford, Lead Genomic Data Scientist for Rare Disease, to explain how genomics is helping us better understand rare conditions.

You can also find a series of short videos explaining some of the common ... more

YouTube

When people think of midwives, they often think about pregnancy and birth, but the reality of modern midwifery is far broader.

In this episode of Behind the Genes, our guests explore the many different roles midwives play across healthcare, from cli... more

YouTube

In this explainer episode, we’ve asked Kate Stanbury, research midwife on the Generation Study, to tell us more about the vital role that midwives play.

You can also find a series of short videos explaining some of the common terms you might encount... more

YouTube

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Recent Guests

Katie Snape
Principal Clinician for Population Health at Genomics England
Genomics England
Episode: Could taking aspirin halve the risk of bowel cancer?
Sir John Burn
Professor of Clinical Genetics
Newcastle University
Episode: Could taking aspirin halve the risk of bowel cancer?
Drew Hyde
Participant in the Cancer Prevention Programme (CAT3 trial)
CAP3 trial participant
Episode: Could taking aspirin halve the risk of bowel cancer?
Jamie Ellingford
Lead genomic data scientist for rare disease
Genomics England
Episode: How can genomics help us understand rare conditions?
Katie Handley
Maternal and Child Health Clinical Lead for the Generation Study
Generation Study
Episode: How is research changing the role of midwives in maternity care?
Fiona Smith
Research Midwife for the Generation Study at Rosie Hospital
Generation Study, Rosie Hospital
Episode: How is research changing the role of midwives in maternity care?
Jess Fletcher
Safety and Quality Midwife at the Rosie Hospital and a Participant on the Generation Study
Rosie Hospital, Generation Study
Episode: How is research changing the role of midwives in maternity care?
Kate Stanbury
research midwife
Generation Study, Genomics England
Episode: What does a midwife do?
Kirsty Irvine
Chair of the Participant Panel
Genomics England Participant Panel
Episode: How is genomic research being guided by patient and participant voices?

Hosts

Florence Cornish
Host of Behind the Genes
Sharon Jones
Host of Behind the Genes

Reviews

4.9 out of 5 stars from 77 ratings
  • Engaging and educational

    For anyone wanting to learn more about genomics but feels overwhelmed by the science, this podcast is for you. The moderator manages to simplify difficult topics through engaging discussions with leading experts in various fields.

    Apple Podcasts
    5
    emilie_scherrer
    United States4 years ago
  • Unmissable

    I work in healthcare and have recently been diagnosed with a rare genetic disease this ticks all my boxes

    Apple Podcasts
    5
    a*savin
    United Kingdom4 years ago
  • Fasinating listening

    Why it is challenging to capture the East Asians data due to the complexity of navigating cultural perceptions and trust.

    Apple Podcasts
    5
    Mandoclarkie
    New Zealand5 years ago
  • Inspiring, practical context for the most important medical innovations of the next decade

    Genomic medicine is complicated and cutting edge, but now has proven an ability to transform healthcare.

    This podcast is the tip of the spear of an essential society level education and re-alignment of healthcare around the new diagnostics and treatments unlocked by genomics

    Apple Podcasts
    5
    nb_bk
    United States5 years ago
  • Fantastic pod cast series

    Great series that covers a range of topics that related to genomics in an accessible and engaging way. Genomics is going to be more and more critical for treating the individual patient in the right way for them - and for preventing their illness in the first place. Impressive line up of interviewees that shows the esteem Genomics England is held in

    Apple Podcasts
    5
    torrich75
    United Kingdom5 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Engaging and educational: Complex genomics made accessible by a capable host.
Unmissable for healthcare professionals seeking patient perspectives.
Fascinating: addresses data challenges in diverse populations.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Could taking aspirin halve the risk of bowel cancer?
Q: How is Genomics England planning to apply these findings in routine care?
By scaling population health measures through the Adults Programme, identifying high-risk individuals via genetic screening and implementing preventive strategies such as aspirin where appropriate, supported by NHS and policy alignment.
Could taking aspirin halve the risk of bowel cancer?
Q: What were the key findings of CAP2 and CAP3 regarding dosage and effectiveness?
CAP2 found a 50% reduction in bowel cancers with a higher aspirin dose; CAP3 showed that a lower, more tolerable dose achieved similar preventive effects with fewer side effects, supporting the idea that smaller doses may be sufficient.
Could taking aspirin halve the risk of bowel cancer?
Q: What was the rationale behind using aspirin in people with Lynch syndrome?
Historical observations suggested aspirin reduced cancer incidence; CAP trials built on this by testing whether aspirin could prevent bowel cancer in high-risk individuals, with dose-ranging studies to balance efficacy and safety.
How is research changing the role of midwives in maternity care?
Q: What message would you leave listeners with about midwives and research?
The guests encourage curiosity and bravery, emphasizing that embracing genomics can improve care, and that informed decision-making and multidisciplinary support are key to safe, effective practice.
How is research changing the role of midwives in maternity care?
Q: How confident do midwives generally feel about discussing genomics with families?
The hosts acknowledge that confidence is variable; while some midwives may feel uncertain, they have support from specialty roles (fetal medicine midwives, screening teams) and a strong patient record system to help navigate conversations and referrals.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About Behind the Genes

What is Behind the Genes about and what kind of topics does it cover?

This series centers Genomics England's work in genomic healthcare, balancing technical explanations with real-world experiences from families affected by rare conditions and cancer. Episodes frequently examine data governance, patient and participant voices shaping policy, and how genomic research translates to the NHS, including newborn sequencing initiatives, de-identified data safeguards, and the promise of precision medicine. A standout element is the blend of lived experience with clinical and governance expertise, plus a focus on accessible explanations for complex genomics concepts. Potential listeners include healthcare professionals, researchers, patient advocates, and families seeking clear insight into how genomics is changing ca... more

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Which podcasts are similar to Behind the Genes?

These podcasts share a similar audience with Behind the Genes:

1. How To Fail With Elizabeth Day
2. Red Whale Primary Care Pod
3. More or Less
4. The Life Scientific
5. BBC Inside Science

How many episodes of Behind the Genes are there?

Behind the Genes launched 5 years ago and published 100 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Behind the Genes?

Recent guests on Behind the Genes include:

1. Katie Snape
2. Sir John Burn
3. Drew Hyde
4. Jamie Ellingford
5. Katie Handley
6. Fiona Smith
7. Jess Fletcher
8. Kate Stanbury

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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