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Artwork for Race Against Mind: An Alzheimer's Prevention Investigation

Race Against Mind: An Alzheimer's Prevention Investigation

Sarah Kuhn
Apoe4
Alzheimer's Disease
Sleep
Mediterranean Diet
Cholesterol
BDNF
Perimenopause
Apoe-4
Exercise
Nutrition
Fitness
GPLD1
VO2 Max
Resistance Training
Apolipoprotein E4
Apolipoprotein B
Statins
Ptau217
Alcohol
Metabolic Health

Race Against Mind is an Alzheimer's prevention investigation hosted by Sarah Kuhn, a double APOE4 carrier with a family history of early-onset Alzheimer's disease. Instead of waiting, Sarah started asking a different question: what does the research actually say, and what happens when you take it seriously?

Each episode goes deep on one piece of the prevention puzzle: exercise, sleep, metabolic h... more

PublishesWeeklyEpisodes10Founded2 months ago
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FitnessHealth & Fitness

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Artwork for Race Against Mind: An Alzheimer's Prevention Investigation

Latest Episodes

Chronic stress is one of the most underappreciated risk factors for Alzheimer's disease and for APOE4 carriers, the relationship between stress hormones and neurodegeneration is not just additive. It's amplified through a distinct biological mechanis... more

Women account for two-thirds of all Alzheimer’s cases. For a long time, the explanation was simple: women live longer. But that doesn’t fully account for the gap. What the research is now pointing to is that something happens during the perimenopausa... more

I was having a glass of wine most nights when I got my Oura Ring. Not a lot, or so I thought. Within weeks the data told a different story. My HRV baseline runs in the nineties. On mornings after drinking, even one glass, it dropped to the thirties o... more

Someone told me to give my mom coconut oil after her Alzheimer's diagnosis. My mom couldn't remember I was pregnant at the time. The person meant well. The advice was wrong. And for someone with APOE4 genetics — which both my mom and I carry — it was... more

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Host

Sarah Kuhn
Host of Race Against Mind: An Alzheimer's Prevention Investigation

Reviews

4.8 out of 5 stars from 14 ratings
  • Relatable as fellow APOE4/4 carrier

    I was apprehensive to listen, but am glad I did. The summation ate end of episode 1 “More information reveals more complexity” spoke to me, I wish there was a clear map but my own somewhat parallel though also unique journey has revealed a similar perspective as well. Thank you!

    Apple Podcasts
    5
    72mwc
    United Statesa month ago
  • Hello from a fellow APOE 4 with young kids.

    Thank you for doing this

    Apple Podcasts
    5
    kbeksk
    United States2 months ago

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Frequently Asked Questions About This Podcast

What is This Podcast about and what kind of topics does it cover?

A deep-dive show focused on Alzheimer's prevention through lifestyle, genetics, and data-driven experimentation. Across episodes, topics center on APOE4-related risk, metabolic and cardiovascular health, sleep and circadian biology, exercise protocols, nutrition strategies, hormones, and the role of biomarkers in personal risk management. The host blends lived experience with scientific context, sharing how data, experiments, and conversations with doctors shape practical prevention plans. Notable throughlines include the limits of diet alone to mitigate genetic risk, the interplay between brain and heart health, and a consistent emphasis on long-term, sustainable changes over extreme fixes. The format tends to be highly personal and eviden... more

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1. The Mel Robbins Podcast
2. The Peter Attia Drive
3. Huberman Lab
4. The Dr. Hyman Show
5. The Dr. Gabrielle Lyon Show

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this podcast launched 2 months ago and published 10 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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