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Artwork for Progress, Potential, and Possibilities Podcast / Show

Progress, Potential, and Possibilities Podcast / Show

Ira Pastor
Artificial Intelligence
Alzheimer's Disease
Antimicrobial Resistance
Public Health
Mental Health
Gene Therapy
Vaccines
Clinical Trials
Breast Cancer
Telehealth
ALS
Trauma-Informed Care
Healthcare Technology
One Health
Quantum Computing
Telemedicine
Influenza
Cancer Research
Human Rights
Smart Hospitals

Interviews and Discussions With Fascinating People Who are Creating A Better Tomorrow For All Of Us - Host - Ira S. Pastor

PublishesDailyEpisodes944Founded6 years ago
Number of ListenersCategories
ScienceHealth & Fitness

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Artwork for Progress, Potential, and Possibilities Podcast / Show

Latest Episodes

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Nuclear power has a scale problem: conventional plants are enormous, expensive projects that can take years to build. Hadron Energy wants to take a different approach with a factory-manufactured, 10-megawatt light-water microreactor... more

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The world doesn't have a shortage of promising medical discoveries. The real challenge is turning those discoveries into safe, effective, accessible treatments. What separates a breakthrough idea from a successful therapy? How could... more

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What if we stopped thinking about antibodies as simply drugs that bind to one target - and started thinking about them as engineered molecular machines? Today we're talking about a bispecific antibody that targets both EGFR and LGR5... more

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What happens when you're 19 years old, physically fit, a collegiate wrestler, and you suddenly find yourself hospitalized for three days with influenza? Today's guest, Zachery Lang, experienced exactly that - and his story offers an... more

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Recent Guests

Robert Geho
Co-founder and CEO of Diasome Pharmaceuticals with more than three decades in diabetes, drug delivery and biotechnology
Diasome Pharmaceuticals
Episode: Can We Rethink Insulin? How Targeting the Liver Could Change Treatment | Robert Geho - Co-Founder and CEO, Diasome Pharmaceuticals
Steve Bloom
President and Chair of the CLL Society and biopharmaceutical commercial strategy executive
CLL Society
Episode: Chronic Lymphocytic Leukemia: Why Aren’t Patients Getting the Right Tests and Treatments? | Kirsten Axelsen - Senior Advisor, Charles River Associates & Steve Bloom - President and Chair, CLL Society
Kirsten Axelsen
Senior Advisor focused on healthcare policy, economics, and market access
Charles River Associates
Episode: Chronic Lymphocytic Leukemia: Why Aren’t Patients Getting the Right Tests and Treatments? | Kirsten Axelsen - Senior Advisor, Charles River Associates & Steve Bloom - President and Chair, CLL Society
Desmond Wheatley
President, CEO, and chairman of Beam Global with more than three decades leading technology and infrastructure businesses
Beam Global
Episode: From EV Charging To Disaster Response: Rethinking Energy Infrastructure | Desmond Wheatley - President, CEO, and Chairman of the Board, Beam Global
Natalie Ma
Chief Business Officer and co-founder of Deep Origin with a PhD in Molecular Biology from Yale University
Deep Origin
Episode: Building Virtual Humans To Predict Drug Safety | Dr. Natalie Ma, Ph.D. - Chief Business Officer & Co-Founder - Deep Origin
Abigail Livny-Ezer
Neuroscientist, neuropsychologist, and clinical neuroimaging researcher.
Sheba Medical Center
Episode: The Future of Neuroimaging: AI, Brain Networks & Better Clinical Decisions | Dr. Abigail Livny-Ezer, Ph.D. - Director, C.BIRD Center (Clinical Brain Imaging Research & Development Center) - Sheba Medical Center
Connor DeWolfe
Actor, content creator and mental-health advocate who shares his experiences living with ADHD
Episode: Can ADHD Medication Last All Day? The Science Behind a New Approach | Dr. Matthew Brams, MD, - Chief Medical Officer, Cingulate Therapeutics; Connor DeWolfe, Mental Health Advocate
Matthew Brams
Board-certified adult and child psychiatrist and clinical researcher specializing in ADHD and autism spectrum disorders
Cingulate Therapeutics
Episode: Can ADHD Medication Last All Day? The Science Behind a New Approach | Dr. Matthew Brams, MD, - Chief Medical Officer, Cingulate Therapeutics; Connor DeWolfe, Mental Health Advocate
Joseph Geraci
Mathematician, mathematical physicist, medical scientist and machine-learning innovator
NetraMark
Episode: From Quantum Physics To Precision Medicine: The AI Search For Hidden Patterns | Dr. Joseph Geraci, Ph.D. - Co-Founder, Chief Technology Officer and Chief Scientific Officer, NetraMark

Hosts

Ira S. Pastor
Host of Progress, Potential, and Possibilities Podcast / Show
Ira Pastor
Host of the show

Reviews

4.6 out of 5 stars from 11 ratings
  • Unveiling the Secrets of Healthy Longevity

    The episode with Dr. Sofiya Milman on "Progress, Potential, and Possibilities" offers a fascinating dive into the world of centenarians and the genomic mechanisms that protect against age-related diseases. Dr. Milman's dedication to this field is evident, and her journey from college to post-doctoral research is a testament to her passion for physiology and genetics. This episode is a must-listen for anyone interested in the science of healthy aging.

    Apple Podcasts
    5
    I value the unique angle
    Austria3 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

The show pairs science with real-world impact, including patient and policy angles
Guests bring diverse expertise, from biotech to AI in medicine, delivering actionable insights
Listeners appreciate data-driven, deeply informed discussions with experts

Chart Rankings

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Apple Podcasts
#190
Colombia/Science

Talking Points

Recent interactions between the hosts and their guests.

Can AI Help Detect Disease Before Your Pet Gets Sick? | Dr. Ragen McGowan, Ph.D - Director of Global Digital & AI Product Development - Nestlé Purina
Q: Could you a little, again, take a little time to what went into this study, because it's pretty impressive.
The retrospective study compared litter-box monitor data from cats with chronic kidney disease and cats with no known conditions. Researchers found a distinctive profile involving weight changes and aspects of litter-box visits, then used it to flag patterns for owners to discuss with veterinarians. The monitor does not diagnose kidney disease.
Can AI Help Detect Disease Before Your Pet Gets Sick? | Dr. Ragen McGowan, Ph.D - Director of Global Digital & AI Product Development - Nestlé Purina
Q: Talk a little bit, introduce this principle of digital phenotyping and what it really means in your realm.
Digital phenotyping uses connected sensors and technology to continuously measure observable characteristics. It can show how a pet's behavior and other patterns change over time compared with that individual's baseline, helping owners and veterinarians notice signals that may warrant evaluation.
Can We REVERSE Cancer Drug Resistance? The New Science of Fighting Cancer | Dr. John Yu, MD - Founder and CEO, Kairos Pharma - Professor and Clinical Chief of Neurosurgery, Cedars-Sinai
Q: And talk a little bit because they have nice safety profile, PSA levels coming down, but the progression fee survival numbers, which I don't think you thought would be as good as they were, but it looked really good out to 13 months. And this is a really tough population. So talk a little bit about what you found in this interim analysis.
Yu reports that patients receiving ENV105 with a changed anti-androgen therapy had tumor growth control extending beyond a year, compared with historical median progression-free survival of about four to six months after switching therapies. He also says PSA levels fell to about 35% of baseline.
Can We REVERSE Cancer Drug Resistance? The New Science of Fighting Cancer | Dr. John Yu, MD - Founder and CEO, Kairos Pharma - Professor and Clinical Chief of Neurosurgery, Cedars-Sinai
Q: Talk a little bit about what we know in 2026, because it's not just one thing. I mean, whether it's compensatory signaling or the ability of cancer to understand DNA repair and do it really well, or immune evasion, cancer cells are very good at getting out of the bad situation, and just lay the landscape of what drug resistance and oncology means to the world in 2026, because it's a big problem.
Yu explains that cancer can resist therapies through mutations, decoy receptors, alternate growth pathways, and stem cell-like properties that help cells survive drugs and radiation. He identifies CD105 as one mechanism that can drive this resistant state.
Can a Virus Turn Cancer Against Itself? The Next Era of Cancer Immunotherapy | Jared Kelly - Chief Executive Officer, Oncolytics Biotech
Q: Talk about why we're at an inflection point for this type of technology.
Kelly says oncolytic viruses could gain momentum as clinical data and approvals accumulate, comparing the sector's potential rise with antibody-drug conjugates and noting that systemic delivery may distinguish pelareorep.

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Frequently Asked Questions About This Podcast

What is This Podcast about and what kind of topics does it cover?

This program features in-depth conversations with researchers, clinicians, and industry leaders who are actively shaping science, health, and technology for a better tomorrow. Episodes frequently tackle cutting-edge biomedical topics, AI-enabled healthcare, innovative therapies, and the practical implications of research—from patient advocacy and translational medicine to the commercialization of new technologies. Notable throughlines include the patient perspective, the ethics and regulatory paths of emerging treatments, and the real-world impact of scientific advances on health outcomes and industry strategy. A standout aspect is the diversity of guests across biotech, clinical medicine, environmental health, and AI-driven healthcare tool... more

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1. The Peter Attia Drive
2. Huberman Lab
3. The AI Daily Brief: Artificial Intelligence News and Analysis
4. The Ezra Klein Show
5. Call Me Back - with Dan Senor

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this podcast launched 6 years ago and published 944 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on this podcast?

Recent guests on this podcast include:

1. Robert Geho
2. Steve Bloom
3. Kirsten Axelsen
4. Desmond Wheatley
5. Natalie Ma
6. Abigail Livny-Ezer
7. Connor DeWolfe
8. Matthew Brams

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