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Physiologically Speaking

Brady Holmer
Creatine
Protein
VO2 Max
Nutrition
Endurance Training
Cognitive Function
Physical Performance
Ketones
Ketone-Iq
Everyday Health
Harvard T. Chan School Of Public Health
Kidney Stones
Weight Loss
Dietary Guidelines For Americans
Thermic Effect Of Food
Endurance Sports
Exogenous Ketones
Heat Training
Marathon Training
Exercise Physiology

A weekly podcast highlighting recent research in science. www.physiologicallyspeaking.com

PublishesTwice monthlyEpisodes44Founded3 years ago
Number of ListenersCategories
Life SciencesHealth & FitnessNutritionScience

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Latest Episodes

I’ve been experimenting with exogenous ketones for several years now, and you’ve probably heard me talk about them once or twice if you’re a regular reader or listener. I frequently get asked how (and why) I use ketones in my own training, so I decid... more

Greetings!

I’m incredibly excited to share this video with you for this week’s edition of the newsletter.

I sat down with Dr. Latt Mansor of Ketone-IQ to dive deep into a brand-new study in cyclists showing that taking ketones after exercise enhanc... more

In this video, I’m giving you a full tour of my home gym (or garage gym, or “pain cave,” depending on the day) and reviewing some of the equipment I’ve been using to support my marathon training, cross-training, strength work, and general health.

My... more

I bought a weighted vest after my running injury last year, and I was immediately hooked (here’s the plate carrier I got… no affiliation).

Initially, I figured it would be a good rehab tool and a bridge between walking and returning to run. But now,... more

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Recent Guests

Dr. Latt
Guest expert (cardiovascular metabolism researcher)
KU Leuven collaboration partner
Episode: The Ketone Study I've Been Waiting For...
Michael Easter
Author and researcher on rucking and endurance training
Author, The Comfort Crisis
Episode: The Benefits (and Science) of Walking with Weight
Dr. Nicholas Fabiano
Brain health researcher and co-author of a review article on creatine supplementation
Episode: Creatine for the Brain with Dr. Nicholas Fabiano
Kristi Storoschuk
PhD candidate in Muscle Physiology at Queen's University, studying the effects of nutrient timing and high-intensity interval training.
Queen's University
Episode: Is Zone 2 Training Optimal for Mitochondrial Health? My Interview with Kristi Storoschuk
David Roche
Running Coach and Ultra Runner
Founder of a coaching program for endurance athletes
Episode: David Roche Wants to “Science the Sh*t” Out of UltraRunning
Brady Holmer
Division I athlete and marathon runner
Episode: Creatine for endurance athletes, running a 2:26 marathon on 4 days per week, and more.

Host

Brady Holmer
Co-host of Physiologically Speaking, recently joined Ketone IQ's scientific advisory committee

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Physiology Friday #285: Q&A on Ketones, Creatine, Endurance Nutrition, Heat Training, and More!
Q: How do you deal with running in extreme heat?
I manage heat by ensuring proper hydration, dressing appropriately, and adjusting expectations when training in higher temperatures.
Physiology Friday #285: Q&A on Ketones, Creatine, Endurance Nutrition, Heat Training, and More!
Q: Do you have a mental performance conditioning routine?
I don't have anything formal, but I practice self-talk and use my workouts to build mental performance.
Physiology Friday #285: Q&A on Ketones, Creatine, Endurance Nutrition, Heat Training, and More!
Q: How do you manage injury prevention with all that training load?
I focus on load management, proper recovery, and ensuring I work on my running form to prevent injuries.
Physiology Friday #285: Q&A on Ketones, Creatine, Endurance Nutrition, Heat Training, and More!
Q: Do you cycle off creatine usage or does it not matter?
There's no evidence that you need to cycle off creatine, and it's not a supplement that causes hormonal desensitization, so you can take it indefinitely.
Physiology Friday #285: Q&A on Ketones, Creatine, Endurance Nutrition, Heat Training, and More!
Q: What are your thoughts on exogenous ketones? Why do you take them when and how often?
I believe they are not a miracle supplement but can be beneficial for recovery and cognitive performance, particularly when training hard.

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Frequently Asked Questions About Physiologically Speaking

What is Physiologically Speaking about and what kind of topics does it cover?

This show centers on practical science for athletes, especially runners, with a strong focus on physiology, nutrition, and training strategies. Recent episodes cover topics like rucking and endurance training, VO2 max and cardiorespiratory fitness, protein quality and dietary protein needs, creatine and brain health, ketones for cognition, and navigating health misinformation online. The discussion often blends personal running experience with scientific insights, featuring debates about injury prevention, fueling strategies, and the real-world implications of laboratory measures for everyday training and health. A notable pattern is the willingness to challenge mainstream narratives, test common fitness claims, and translate complex scienc... more

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Which podcasts are similar to Physiologically Speaking?

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1. Out and Back
2. Some Work, All Play
3. The Extramilest Podcast
4. excellence, actually
5. Huberman Lab

How many episodes of Physiologically Speaking are there?

Physiologically Speaking launched 3 years ago and published 44 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Physiologically Speaking?

Recent guests on Physiologically Speaking include:

1. Dr. Latt
2. Michael Easter
3. Dr. Nicholas Fabiano
4. Kristi Storoschuk
5. David Roche
6. Brady Holmer

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