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Longevity by Design

InsideTracker
Healthspan
Aging
Longevity
Obesity
Exercise
Glp-1
Health Optimization
Diabetes
Cardiovascular Health
Senolytics
Artificial Intelligence
Aging Research
Protein Intake
Nutritional Dark Matter
Alzheimer's Disease
Weight Loss
Genetics
Longevity Research
Exercise Physiology
Wearable Technology

Longevity by Design is your go-to podcast for science-backed conversations on living a longer, healthier life, with honesty about what the evidence actually shows. Hosted by a rotating panel of InsideTracker leaders, including Renee Deehan, SVP of Science and AI, this show dives into cutting-edge research, addresses bias and misinformation in health, and explores the intersection of preventive med... more

PublishesTwice monthlyEpisodes111Founded6 years ago
Number of ListenersCategories
MedicineHealth & FitnessScience

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Artwork for Longevity by Design

Latest Episodes

In this episode of Longevity by Design, host Renée Deehan, Senior VP of Science, AI & Product, is joined by Will Dzierson, VP of Product & Design, both with InsideTracker, to welcome Ohad Manor, VP of Computational and Precision Health at Thorne. Oha... more

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In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Andrea Maier, Professor in Medicine and Director of the NUS Academy for Healthy Longevity at the National University of Singapore’s School of Medicine. They explore what ... more

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In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Uri Alon, Professor at Weizmann Institute of Science. They explore a systems view of aging that treats longevity as a solvable model, not a grab bag of disconnected theor... more

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In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Paola Sebastiani, Professor of Biostatistics at Tufts Clinical and Translational Science Institute. They explore what centenarians reveal about reaching 100, and why ther... more

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Recent Guests

Ohad Manor
Computational biologist focused on precision health, with experience in academia, Arivale, cancer therapeutics and diagnostics
Thorne
Episode: Longevity By Design 2.0 Episode #1: Why Scientific Validity Isn't Enough
Dr. Andrea Maier
Globally recognized leader in healthy aging and geroscience; professor and director at National University of Singapore
National University of Singapore
Episode: Do Longevity Supplements Really Work?
Uri Alon
Professor, Department of Molecular Cell Biology, Weizmann Institute of Science
Weizmann Institute of Science
Episode: What Houses, Garbage, and Trucks Teach Us About Aging with Dr. Uri Alon
Paola Sebastiani
Professor of Biostatistics at Tufts Clinical and Translational Science Institute, senior investigator with the New England Centenarian Study
Tufts University; New England Centenarian Study
Episode: Born to Live Longer? Inside the Genetics and Biology of Centenarians
Terrie Moffitt
University professor at Duke University and King's College London, author of Dunedin Study work
Dunedin Study/ academia
Episode: Age Faster or Slower? The Surprising Role of Mental Health and Self-Control
David Allison
Dean and Provost Professor at the Indiana University School of Public Health Bloomington; researcher in obesity, nutrition, and health science
Indiana University; Baylor College of Medicine
Episode: Why Most Longevity Advice Gets Weight and Exercise Wrong
Dr. Louise Hecker
Associate Professor of Medicine at Baylor College of Medicine and Research Scientist at the Department of Veterinary Affairs.
Baylor College of Medicine
Episode: Can Psychedelic Mushrooms Slow Aging?
Dr. Nathan Price
A leading pioneer in systems biology and precision health
Buck Institute for Research on Aging
Episode: Engineering Healthspan with Dr. Nathan Price: Is It Finally Possible?
Ronjon Nag
An inventor, educator and serial entrepreneur working in artificial intelligence and longevity science.
Stanford School of Medicine
Episode: How AI Is Redesigning Longevity | Systems Thinking with Dr. Ronjon Nag

Host

Gil Blander
InsideTracker leader and host focused on longevity science

Reviews

4.6 out of 5 stars from 319 ratings
  • Dr Barabasi Nutritional dark matter and the Human food genome

    This was an incredibly informative podcast and I absolutely love the concept of network medicine. I believe that the new era of metabolic reprogramming will depend on our ability to unlock the signals of our networks and in particular the master network control house of our hypothalamus. Likewise if we can achieve Dr. Barabasi’s two moonshots and decode nutritional dark matter to catapult food as medicine we will take charge of the epigenetic levers of health, disease risk and aging. Thanks for ... more

    Apple Podcasts
    5
    Dr. J Pearlman
    Canadaa year ago
  • Love it - but audio needs help

    I’ve been listening to this podcast for years and really enjoy the deep dives into a wide range of health topics. The audio quality could really use some help though. I had to stop listening to the Layne Norton episode because parts of what he was saying would constantly fade in and out. I was hoping turning up the volume would solve it, but it just made the problem more apparent. I will keep trying to listen - I’ve noticed not every episode has issues, but some definitely do. Thank you!

    Apple Podcasts
    5
    santamoniconian
    United Statesa year ago
  • Great podcast!

    This podcast is a constant source of really great conversations and insight. Gil does a great job of bringing on excellent guests and providing very useful information on regular basis. Thanks!!

    Apple Podcasts
    5
    NJ Running guy
    United Statesa year ago
  • Excellent podcast!

    I have been using Inside Tracker since 2021 which is giving me absolute control over my health by knowing exactly what the status of my bio markers are and how they are trending. This podcast is the perfect companion for those who want to be up-to-date on the latest scientific research on healthy aging and longevity in a way that every day people can understand. Great job and keep up the good work!

    Apple Podcasts
    5
    Don-healthy at 65
    United States2 years ago
  • Great resource!

    This is a very informative podcast. I have always had a fear of dying so figuring out how to live better for longer has always been a goal of mine. I especially enjoyed the episode with Eran Segal!

    Apple Podcasts
    5
    HealthySpainaird
    United States2 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Many describe the content as informative, credible, and useful for staying current on longevity and preventive health.
Audio problems, including uneven levels, skips, background noise, and abrupt edits, are recurring complaints.
Some conversations can become too technical or wander from the advertised topic, leaving non-specialist listeners wanting clearer takeaways.
Listeners value the expert guests and research-led discussions, especially when complex findings are connected to practical health questions.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Longevity By Design 2.0 Episode #1: Why Scientific Validity Isn't Enough
Q: How do you best determine which approach is best suited to a particular use case?
Manor says to consider the available data, the outcome sought and how explainable the model must be. Structured biomarker questions may call for simpler statistical models, while language models are useful for conversational explanations, context and follow-up questions.
Longevity By Design 2.0 Episode #1: Why Scientific Validity Isn't Enough
Q: What were some of the major transitions in that journey and what questions have continued to interest you across those different settings?
Manor describes a career spanning academic computational biology, Arivale, cancer therapeutics and diagnostics, and Thorne. Across those roles, his focus has remained using computation to make complex biology understandable and useful to people.
Born to Live Longer? Inside the Genetics and Biology of Centenarians
Q: Why is there no single 'longevity gene' and what does that imply for therapies?
Because aging and longevity arise from many interacting biological pathways, therapies will likely target networks or pathways rather than a lone gene, enabling multiple routes to healthy aging.
Do Longevity Supplements Really Work?
Q: What is your approach to selecting and using supplements in clinical practice?
Prescribe only when there is clear mechanism and human evidence, measure baseline vitamin/mineral status, use targeted, personalized supplementation, and consider randomized trials; avoid one-size-fits-all recommendations.
Do Longevity Supplements Really Work?
Q: What does the evidence say about the effect of multivitamins and minerals on healthspan and aging outcomes in humans?
The evidence is mixed: some small benefits for global cognition and certain conditions exist, but overall for healthy individuals the benefit is modest or absent, and there is no clear survival advantage; benefits are more likely in people with dietary gaps or specific health issues.

Audience Metrics

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Frequently Asked Questions About Longevity by Design

What is Longevity by Design about and what kind of topics does it cover?

Evidence-focused conversations about aging, longevity, and the science of living healthier for longer. Host Gil Blander, an InsideTracker leader, interviews researchers, clinicians, and policy experts about topics including geroscience, genetics, nutrition, mental health, precision medicine, and the use of AI and biomarkers in preventive health. Discussions connect emerging research with practical questions about lifestyle and interventions, while examining the limits of current evidence and the risks of overstating early findings.

The format pairs expert interviews with accessible explanations of complex science, though some conversations go deep into technical detail. Its distinctive focus is the bridge between research and real-world he... more

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Which podcasts are similar to Longevity by Design?

These podcasts share a similar audience with Longevity by Design:

1. Lifespan with Dr. David Sinclair
2. FoundMyFitness
3. The Peter Attia Drive
4. The Dr. Gabrielle Lyon Show
5. Huberman Lab

How many episodes of Longevity by Design are there?

Longevity by Design launched 6 years ago and published 111 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact Longevity by Design?

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What guests have appeared on Longevity by Design?

Recent guests on Longevity by Design include:

1. Ohad Manor
2. Dr. Andrea Maier
3. Uri Alon
4. Paola Sebastiani
5. Terrie Moffitt
6. David Allison
7. Dr. Louise Hecker
8. Dr. Nathan Price

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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