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Artwork for Intelligent Medicine

Intelligent Medicine | The Best of High Tech Medicine and Alternative Modalities

Dr. Ronald Hoffman | Pioneering Complementary Medicine Practitioner
Alzheimer's Disease
Autism
Urolithin A
Nitric Oxide
Mitopure
Aging
Nutrition
Sleep
Omega-3 Rejuvenate
Glp-1 Drugs
Mitochondria
Omega-3 Fatty Acids
Metabolic Health
Covid-19
Statins
Xylitol
Cholesterol
Probiotics
Insulin Resistance
Cardiovascular Health

Pioneering complementary medicine practitioner Dr. Ronald Hoffman takes a cutting-edge approach to health, wellness, and aging. He covers both conventional and alternative modalities, as well as nutrition, exercise, and supplements.

PublishesDailyEpisodes1055Founded13 years ago
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Health & FitnessAlternative Health

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Artwork for Intelligent Medicine

Latest Episodes

Leyla Muedin, a registered dietitian nutritionist in New York City, discusses the growing shift from symptom-only “sick care” to a clinically grounded holistic approach to health and recovery. She argues that self-guided wellness routines can leave g... more

• Is there evidence for statins in the treatment of aortic valve stenosis?

• How the bacteria behind gum disease can affect heart health

• Wouldn't it be better to resume taking probiotics after finishing a round of antibiotics?

• Would it be safe to... more

• My 25-year-old son has bipolar disorder and can't tolerate his medications. Any natural recommendations?

• Is chondroitin effective?  It's in my collagen capsules, which I take to hopefully reduce wrinkles

• I believe I am still suffering from the ... more

Naturopathic gastroenterologist Mark Davis, ND (FABNG), discusses his work in fecal microbiota transplantation (FMT), research, and integrative approaches to GI disease. Davis explains FMT history, screening criteria, delivery methods, how it differs... more

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Recent Guests

Will Van Derveer
Co-author of Psychedelic Therapy, medical doctor
Co-author of Psychedelic Therapy; medical doctor
Episode: Breaking New Ground: Psychedelics in Modern Psychiatry, Part 2
Keith Kurlander
Co-author of Psychedelic Therapy, medical professional
Co-author of Psychedelic Therapy; medical professional
Episode: Breaking New Ground: Psychedelics in Modern Psychiatry, Part 2
Dr. Jeffrey Bland
PhD biochemist, founder of the Personalized Lifestyle Medicine Institute and IFM
Institute for Functional Medicine / Personalized Lifestyle Medicine Institute
Episode: Intelligent Medicine Radio for July 25, Part 1: Breakthroughs in Gene Editing Promise to Vanquish Aging
Leyla Muedin
Registered Dietitian Nutritionist
Private practice
Episode: Leyla Weighs In: Suppressing Belly Fat
Leyla Mutin
Resident nutritionist
Episode: Q&A with Leyla, Part 1: Nature or Nurture
Dr. Susan Trachman
Board-certified psychiatrist and author of It's Not Just In Your Head
Psychology Today contributor
Episode: Beyond the Mind: The Interplay of Mental and Physical Health, Part 1
Susan Trachman
Board-certified psychiatrist and author
Private practice / author of It's Not Just In Your Head
Episode: Beyond the Mind: The Interplay of Mental and Physical Health, Part 2
Nikki Schultek
Co-founder of the Alzheimer's Pathobiome Initiative
Alzheimer's Pathobiome Initiative
Episode: Infections and the Mind: A New Perspective on Alzheimer's, Part 2
David Chernoff
Chief Medical Officer, Setpoint Medical
Setpoint Medical
Episode: Vagus Nerve Stimulation for Rheumatoid Arthritis and Beyond, Part 1

Hosts

Dr. Ronald Hoffman
Host with a focus on integrative and conventional medicine; affiliated with Intelligent Medicine team.
Leyla Mutin
Resident nutritionist providing nutrition-focused perspectives and Q&A guidance.

Reviews

4.5 out of 5 stars from 266 ratings
  • Too many ads!

    Why so many ads?! Still like the show and content, but when you headline stiff person syndrome I expect to hear something a little more in depth besides that it’s a rare disease.

    Stop with the teaser headlines please.

    Apple Podcasts
    1
    Utility Bee
    United States2 years ago
  • Throws out information without sources

    Twins study: very poorly reviewed. Sounds like an infomercial.

    Apple Podcasts
    2
    Cheitkamp
    United States3 years ago
  • Going down the hill

    This was once a show that was more real info with some science backing, Now off the rails And fringe Too bad. This episode on neurodegenerative toxins is sooo weak; she is just reading some statements but really offering nothing to substantiate. It is really in the end telling us nothing of value…the show also just pushes its own supplements

    Apple Podcasts
    2
    Peter Ahl
    United States3 years ago
  • Fantastic info about movement for seniors

    Just listened to the 2-part interview with Movement for Life creator Hedy and I’m so inspired to share it with my senior parents. It’s wonderful to hear about exercise for seniors that’s so accessible and life affirming. Such great info in there!

    Apple Podcasts
    5
    Ariel A K
    United States3 years ago
  • The Best in both Conventional and Complimentary Medicine Doctor

    I've been listening to Dr. Hoffman for decades because he is a trusted source for both conventional and complimentary medicine. He is a true GEM for the reason that he tells it like it really is, not just from his own opinion but always based on facts. I can always count on looking to him for the latest information on what the truth is concernning the latest studies on things, but he will bring out all the truth, actual data or additional studies so that we can get the real story and not just a ... more

    Apple Podcasts
    5
    big fat zero 2.0
    United States4 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Guests are credible with strong data-driven discussions.
Shows deep expertise and practical health strategies.
New listeners appreciate actionable health tips and interviews.
Long-time fans praise the blend of conventional and alternative perspectives.
Listener feedback is mixed on ad intensity but values the science.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Q&A with Leyla, Part 2: Lithium Orotate for Therapeutic Benefit
Q: Martha asks if exercising fasted is necessary and what benefits it offers.
Dr. Hoffman explains that fasting exercise can improve insulin sensitivity and fat burning, discusses practical considerations for beginners, and notes that appetite and energy balance can fluctuate with fasting workouts.
Q&A with Leyla, Part 2: Lithium Orotate for Therapeutic Benefit
Q: Danny asks about lithium orotate in brain health protocols and whether higher doses (20 mg) are acceptable.
Dr. Hoffman says there is not long-term human data, suggests cautious dosing, compares to higher-dose prescription lithium, and emphasizes the need for long-term trials before drawing conclusions about cognitive preservation benefits.
Q&A with Leyla, Part 2: Lithium Orotate for Therapeutic Benefit
Q: June asks about a 79-year-old woman on a keto diet with very high LDL but good triglycerides and HDL.
Dr. Hoffman explains the LDL targets by risk and introduces the Lean Mass Hyper Responder concept, noting that high LDL on keto can occur with low triglycerides, and that imaging and overall metabolic health should guide decisions, including the potential role of statins or alternatives based on risk stratification.
Q&A with Leyla, Part 1: Nature or Nurture
Q: What do we got in the mailbox, Leyla?
A listener asks about natto kinase versus statins for plaque reduction. The discussion compares plaque regression and LDL changes, noting that natto kinase may reduce plaque more than statins in some measures, but cautions that LDL lowering does not always correspond to plaque dissolution and that combination therapy could be beneficial depending on the individual case.
Intelligent Medicine Radio for July 25, Part 1: Breakthroughs in Gene Editing Promise to Vanquish Aging
Q: What's your take on hydrogen as a healing modality and what should people look for in a hydrogen therapy device?
Hydrogen shows potential as an antioxidant that can reduce inflammation and support detoxification, but there are practical hurdles like dosage, delivery method, and device quality; more research is needed to standardize effective protocols and ensure safety.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About Intelligent Medicine

What is Intelligent Medicine about and what kind of topics does it cover?

This show blends conventional medicine with complementary and lifestyle approaches, often featuring in-depth conversations with researchers, clinicians, nutritionists, and investigative journalists. Episodes frequently cover energy metabolism, mitochondrial function, adrenal health, sleep, and cognitive aging, alongside critical examinations of medical research integrity, regulatory processes, and big-pharma dynamics. A distinctive element is the frequent integration of practical diet, supplement, and wellness strategies with rigorous debate about evidence and policy, plus a steady stream of sponsor messages that align with consumer health products. Listeners are likely drawn to a broad, integrative view of health, from clinical insight to ... more

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Which podcasts are similar to Intelligent Medicine?

These podcasts share a similar audience with Intelligent Medicine:

1. The Dr. Hyman Show
2. The Human Upgrade: Biohacking for Longevity & Performance
3. The Genius Life
4. The Cabral Concept
5. The Root Cause Medicine Podcast

How many episodes of Intelligent Medicine are there?

Intelligent Medicine launched 13 years ago and published 1055 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Intelligent Medicine?

Recent guests on Intelligent Medicine include:

1. Will Van Derveer
2. Keith Kurlander
3. Dr. Jeffrey Bland
4. Leyla Muedin
5. Leyla Mutin
6. Dr. Susan Trachman
7. Susan Trachman
8. Nikki Schultek

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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