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Epilepsy Sparks Insights

Torie Robinson
Epilepsy
Mental Health
Dravet Syndrome
Quality Of Life
Seizures
Opm-Meg
Gene Therapy
Pediatric Neurology
Neurology
Depression
Ketogenic Diet
Acute Symptomatic Seizures
Sleep Disorders
Consciousness
Seizure Classification
Drug-Resistant Epilepsy
EEG
Neurosurgery
Cenobamate
Intellectual Disability

Sparking interest and understanding in the epilepsies whilst bridging the communication gap between epilepsy patients, clinicians, scientists, geneticists – and the world. Hosted by Torie Robinson. **NOT FOR CLINICAL OR PATIENT DECISION-MAKING* Visit www.torierobinson.com & www.epilepsysparks.com.

PublishesWeeklyEpisodes277Founded6 years ago
Number of ListenersCategories
Health & FitnessMedicineScienceLife Sciences

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Artwork for Epilepsy Sparks Insights

Latest Episodes

Why do around 30% of people with epilepsy still have uncontrolled seizures despite decades of new antiseizure medications? Graeme Sills, PhD, explains the leading theories behind drug resistance - and how a better understanding of the brain could tra... more

Could a brain implant do more than reduce seizures? Dr. Vikram Rao explains how responsive neurostimulation (RNS) is changing the treatment of epilepsy, why researchers think it may work differently than first imagined, and how the technology is help... more

Most people think every cell in their body contains exactly the same DNA. It turns out that's not always true. Epilepsy genetics researcher Dr. Stéphanie Baulac explains mosaicism, how tiny genetic mutations can exist in just a small number of brain ... more

Could inflammation and the blood-brain barrier help explain why some seizures remain uncontrolled? Prof. Colin Doherty discusses emerging research into immune activity in epilepsy, how steroids may temporarily improve seizure control, and why future ... more

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Recent Guests

Graeme Sills
Pharmacologist and senior lecturer, epilepsy research and therapeutics expert
University of Glasgow
Episode: Why Don't Antiseizure Medications Work for Everyone? - Graeme Sills, PhD
Vikram Rao
Epileptologist and professor of neurology at UCSF
University of California, San Francisco
Episode: The Brain Implant That May Do More Than Reduce Seizures: RNS - Dr. Vikram Rao
Stéphanie Baulac
Researcher at Paris Brain Institute
Paris Brain Institute
Episode: Just a Few Brain Cells Can Cause Epilepsy: Mosaicism - Dr. Stéphanie Baulac
Colin Doherty
Neurologist discussing immune and autoimmune aspects of epilepsy
[Not explicitly stated in transcript]
Episode: Could Immunotherapy Could Control Seizures? - Prof. Colin Doherty
Dr. Manny Bagary
Epileptologist, Somnologist and Neuropsychiatrist
Episode: Ketones Are Changing Your Brain - Epilepsy! - Dr. Manny Bagary
Neha Kaul
Ketogenic dietician
Unspecified in transcript
Episode: The Epilepsy Diet Most People Get Wrong - Keto - Dr. Neha Kaul
Jacob Pellinen
Neurologist and epileptologist
University of Colorado
Episode: Focal Epilepsy Onset Later In Life - With Origins In Childhood - Dr. Jacob Pellinen
Dr. Laurie Miller
Clinical neuropsychologist
Memo Rehab
Episode: Can You Improve Memory In Epilepsy? - Dr. Laurie Miller
Mamta Singh
Professor of medicine specializing in high-volume epilepsy care
AIIMS Delhi
Episode: Inside One Of The World’s Busiest Epilepsy Clinics - Prof. Mamta Singh

Host

Torie Robinson
Host of Epilepsy Sparks Insights

Reviews

4.9 out of 5 stars from 49 ratings
  • Strong science-based content

    As a a cognitive neuroscientist and parent of a child recently diagnosed with epilepsy, I truly appreciate you sharing these well-grounded scientific insights! These short podcasts are accessible and are guiding me to other helpful resources - thank you!

    Apple Podcasts
    5
    Meaghan P PhD
    United States10 months ago
  • Informative, enjoyable, and refreshingly frank

    My girlfriend has epilepsy and this has provided me with real insight into how the condition affects her day to day, week to week, and month to month (because things can vary so much!). It’s presented in an easy-to-understand format and is surprisingly witty.

    Apple Podcasts
    5
    Reaper_FBB
    United Kingdom5 years ago
  • Excellent podcast

    Great interviews with some really interesting people. All presented in a that make difficult and complicated subject reasonably easy to understand

    Apple Podcasts
    5
    TPKJ
    United Kingdom5 years ago
  • Great show and overdue

    It’s great to hear content like this. Anybody who has an interest in epilepsy for any reason will find this to be a must listen

    Apple Podcasts
    5
    Poddy838
    United Kingdom5 years ago
  • Abbeymary

    Great to listen too. Informative, funny, practical, educational and a must listen for all involved in the Epilepsy world. Thanks a million for sharing knowledge and insights into this important topic. Much appreciated. A mum x

    Apple Podcasts
    5
    MaryAbbey
    United Kingdom5 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Guests provide practical, actionable insights for clinicians and families.
Content balances rigorous science with accessible explanations, making it useful for both pros and informed patients.
Clear, science-driven discussions that translate well to clinical practice.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

The Brain Implant That May Do More Than Reduce Seizures: RNS - Dr. Vikram Rao
Q: What is RNS and how does it work in the brain?
RNS is an implant that listens to brain activity and delivers electrical stimulation when abnormal activity is detected, aiming to prevent seizures by stabilizing neural networks; it can target one or multiple seizure foci and, in some cases, a hub like the thalamus to influence broader brain networks.
Just a Few Brain Cells Can Cause Epilepsy: Mosaicism - Dr. Stéphanie Baulac
Q: What potential does precision medicine offer for treatment?
Precision medicine would aim to suppress or correct the hyperactivation of the mTOR pathway specifically in mutated neurons, ideally without affecting neighboring healthy tissue, potentially reducing seizures and avoiding broad brain exposure.
Just a Few Brain Cells Can Cause Epilepsy: Mosaicism - Dr. Stéphanie Baulac
Q: How many neurons need to be mutated to trigger seizures in FCD?
In many models, as few as about 8,000 mutated neurons can be sufficient to trigger spontaneous seizures, illustrating that a small subset of cells can disproportionately influence the brain's seizure network.
Just a Few Brain Cells Can Cause Epilepsy: Mosaicism - Dr. Stéphanie Baulac
Q: What is focal cortical dysplasia and why is it related to somatic mutations?
FCD is a cortical malformation where neurons migrate abnormally, creating a localized epileptogenic zone. Somatic mutations restricted to brain tissue can drive these malformations without being present in blood, explaining why many cases show no family history and normal germline genetics.
Can Ketogenic Therapy Help More Than Seizures? - Dr. Manny Bagary
Q: What about safety concerns such as cholesterol and long-term cardiovascular risk?
Lipids may rise initially but often normalize or drop below baseline over time; long-term cardiovascular outcomes are not yet fully established, and ongoing lipid monitoring is standard.

Audience Metrics

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Frequently Asked Questions About Epilepsy Sparks Insights

What is Epilepsy Sparks Insights about and what kind of topics does it cover?

A clinically oriented show examining epilepsy from multiple angles, including memory, neuromodulation, surgical pathways, AI-assisted diagnostics, and holistic care. Episodes frequently feature neurologists, epileptologists, researchers, and allied health professionals who share practical insights for improving patient outcomes, translating research into clinical practice, and addressing quality of life beyond seizure control. A notable strength is the emphasis on real-world applications (clinical workflows, scalable care, and technology-enabled diagnostics) delivered in accessible, evidence-informed conversations. The format often includes a physician or researcher as a guest, with the host guiding discussions to highlight actionable takea... more

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Which podcasts are similar to Epilepsy Sparks Insights?

These podcasts share a similar audience with Epilepsy Sparks Insights:

1. Sharp Waves: ILAE's epilepsy podcast
2. Seizing Life
3. Huberman Lab
4. The Diary Of A CEO with Steven Bartlett
5. Global News Podcast

How many episodes of Epilepsy Sparks Insights are there?

Epilepsy Sparks Insights launched 6 years ago and published 277 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Epilepsy Sparks Insights?

Recent guests on Epilepsy Sparks Insights include:

1. Graeme Sills
2. Vikram Rao
3. Stéphanie Baulac
4. Colin Doherty
5. Dr. Manny Bagary
6. Neha Kaul
7. Jacob Pellinen
8. Dr. Laurie Miller

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