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This Week in Startups

Jason Calacanis
Openai
Startups
Openclaw
Artificial Intelligence
Venture Capital
Bittensor
Generative AI
Google
Automation
Meta
Uber
AI Technology
NVIDIA
Entrepreneurship
Technology
AI Agents
Robotics
Anthropic
Tariffs
AI Models

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

PublishesDailyEpisodes1434Founded17 years ago
Number of ListenersCategory
Technology

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Artwork for This Week in Startups

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This Week In Startups is made possible by:

Plaud Plaud.ai/twist

Pilot pilot.com/twist

Agree agree.com

IM8 Health IM8health.com/twist

After watching Elon build out his rocket (and AI) company over the past 20 years... more

This Week In Startups is made possible by:

NetSuite - Netsuite.com/TWiST

Deel - Deel.com/TWiST

Squarespace - Squarespace.com/TWiST

Two days before SpaceX launches the largest IPO in history at a flat $135/share, our VC roundtable drops a scorcher... more

The AI Tutor That Makes Kids Actually Think | E2298

This Week In Startups is made possible by:

Northwest Registered Agent northwestregisteredagent.com/twist

LinkedIn Jobs LinkedIn.com/twist

Shopify shopify.com/twist

Plaud... more

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This Week In Startups is made possible by:

Grasshopper Bank grasshopper.bank/twist

Vanta www.vanta.com/twist

Render render.com/twist

Plaud Plaud.ai/twist

Today’s show:

Anthropic wrote a blog post calling for a gl... more

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Key Facts

Accepts Guests
Accepts Sponsors
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Recent Guests

Bobby Healy
CEO of Manna
Manna (drone delivery)
Episode: The Drone Company Quietly Taking Over Delivery
Ian Laffey
Representative of Theseus
Theseus (autonomous drone navigation)
Episode: The Drone Company Quietly Taking Over Delivery
Lukas Czinger
Co-founder and CEO of Divergent Technologies
Divergent Technologies
Episode: From hypercars to cruise missiles: Lukas Czinger on the future of US defense | E2292
Avi Patel
CEO of Kled, founder and public critic in the controversy over a copied website
Kled
Episode: Avi Patel on the startup that copied Kled and why he called out General Catalyst by name | E2291
Immad Akhund
CEO and founder of Mercury Bank
Mercury Bank
Episode: Avi Patel on the startup that copied Kled and why he called out General Catalyst by name | E2291
Gloria Caulfield
Real estate development executive at Tavistock Development Company
Tavistock Development Company
Episode: Why does Gen Z hate AI?
Garrett Langley
Founder and CEO of Flock Safety
Flock Safety
Episode: Why does Gen Z hate AI?
Raquel Uratsun
CEO and founder of Waabi
Waabi
Episode: The Self-Driving Startup Nobody Saw Coming | E2289
Anastasios Angelopoulos
Co-founder and CEO of Arena (LM Arena)
Arena
Episode: How the 1% Will Own Compute (and What It Means for You)

Hosts

Jason Calacanis
Host of This Week in Startups; prominent entrepreneur and investor.
Alex Wilhelm
Co-host and co-presenter; involved in show discussions and guest interviews.
Lon Harris
Co-host on the program; participates in show discussions.

Reviews

4.3 out of 5 stars from 3k ratings
  • 10min contents + 30min ads

    As title lol

    Apple Podcasts
    1
    Ruedhdhejej
    Taiwana month ago
  • So annoying

    I can’t listen to this guy, can’t stand his voice, he’s just so annoying and a disgusting host

    Apple Podcasts
    1
    Projomni78
    United States3 months ago
  • Not actually about startups!

    Check out the episode titles. They are related to diverse popular topics of the day (big tech, new tech, news), but not really about startups.

    Apple Podcasts
    1
    hhsuey
    United States4 months ago
  • Unrivaled Startup Podcast

    Absolutely, positively, 100% the best startup podcast out there! More valuable than a 4 year Computer Science degree if you really want to know how to build, operate and run a company. The Unicorn of startup podcasts 🦄🦄🦄🦄🦄🦄🦄🦄🦄🦄

    Apple Podcasts
    5
    Niall Dennehy
    Ireland6 months ago
  • It’s like candy for your ears

    These guys are A1! I’ve been listening for almost 3 years now, and I can confirm the show is gold. The content they discuss is diverse, but they always discuss things related to the startup ecosystem in almost every episode. One thing I’ve really appreciated more and more is their talent for having engaging discussions with startup founders; you can tell they care.

    Apple Podcasts
    5
    App user Brian
    United States7 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Guest diversity ranges from founders to topVCs; the quality is generally high.
Shows deep founder-first insights and practical startup playbooks.
Ad-heavy format can be off-putting for some listeners.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Spotify
#41
United States/Technology
Apple Podcasts
#87
United States/Technology
Apple Podcasts
#88
United Kingdom/Technology
Apple Podcasts
#101
Canada/Technology
Apple Podcasts
#96
Australia/Technology
Apple Podcasts
#202
Germany/Technology

Talking Points

Recent interactions between the hosts and their guests.

From hypercars to cruise missiles: Lukas Czinger on the future of US defense | E2292
Q: Tell us about how hard it is to come off antidepressants and how your approach helps people taper safely.
Our approach uses hyperbolic tapering to reduce drug exposure gradually along a curve that minimizes withdrawal effects. We pair pharmacologically accurate dose reductions with non-drug strategies and physician oversight, aiming for a smoother transition and lower relapse risk. This is embedded in a care model that can scale with insurers and providers, turning tapering into a reimbursable, data-backed service.
5,000+ Tech Workers Laid Off This Week. It's Just The Beginning. | E2286
Q: How often do the models get refreshed compared to hardware refreshes?
The Go1 OS includes proprietary models that are refreshed every six months, separate from the annual hardware refresh cycle.
5,000+ Tech Workers Laid Off This Week. It's Just The Beginning. | E2286
Q: What does the Go1 cost upfront and what does it cost over time?
Go1 starts at $250,000 as CapEx for the base model, with ongoing monthly service; the Go1 Max starts at $350,000.
5,000+ Tech Workers Laid Off This Week. It's Just The Beginning. | E2286
Q: Do I pay one upfront price and then a different amount every year, or is it a fixed yearly cost?
There is an upfront capex plus a monthly service fee; annual refreshes are included, and there is a fixed ongoing monthly cost.
The Defense Tech Startup YC Kicked Out of a Meeting is Now Arming America | E2280
Q: How does this business work in terms of customers and sales channels?
They work directly with the Army and Air Force, have prime partners, and also engage with large defense contractors who can integrate their propellant and motors into wider end systems for government buyers.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
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Frequently Asked Questions About This Week in Startups

What is This Week in Startups about and what kind of topics does it cover?

A high-velocity interview and roundtable show focused on startups, venture capital, and technology disruption. Episodes frequently center on AI, autonomous systems, enterprise software, funding dynamics, and strategic partnerships, with guests including founders, investors, and operators sharing practical insights about building and scaling businesses. Noteworthy is the recurring ability to blend founder-first perspectives with market-level analysis, plus a propensity for live demos, tactical advice, and controversial takes on industry trends. The format consistently surfaces actionable takeaways for founders, operators, and potential sponsors looking to reach a founder-driven tech audience.

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Which podcasts are similar to This Week in Startups?

These podcasts share a similar audience with This Week in Startups:

1. All-In with Chamath, Jason, Sacks & Friedberg
2. The a16z Show
3. This Week in AI
4. The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch
5. Y Combinator Startup Podcast

How many episodes of This Week in Startups are there?

This Week in Startups launched 17 years ago and published 1434 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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Our systems regularly scour the web to find email addresses and social media links for this podcast. We scanned the web and collated all of the contact information that we could find in our podcast database. But in the unlikely event that you can't find what you're looking for, our concierge service lets you request our research team to source better contacts for you.

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What guests have appeared on This Week in Startups?

Recent guests on This Week in Startups include:

1. Bobby Healy
2. Ian Laffey
3. Lukas Czinger
4. Avi Patel
5. Immad Akhund
6. Gloria Caulfield
7. Garrett Langley
8. Raquel Uratsun

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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