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This Week in Startups

Jason Calacanis
Artificial Intelligence
Openclaw
Openai
Startups
Venture Capital
Bittensor
Google
Japan
Anthropic
Automation
Spacex
Entrepreneurship
Generative AI
Uber
AI Technology
Technology
Cannabis
E-Commerce
Chatgpt
Disney

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world's greatest founders, operators, investors, and innovators.

PublishesDailyEpisodes1499Founded18 years ago
Number of ListenersCategory
Technology

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Artwork for This Week in Startups

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This Week In Startups is made possible by:

Odoo: Odoo.com/twist

Sentry: sentry.io/twist

Stripe: stripe.com/startups

Plaud: Plaud.ai/twist

Today’s show:

Democrats swept the midterms, and a lot of their candidates ... more

This Week In Startups is made possible by:

Every: every.io/

Vanta: www.vanta.com/twist

G2i: g2i.co/twist

Plaud: plaud.ai/twist

Fintrx: www.fintrx.com/

Today’s show:

Democrats took the House and Senate, a... more

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This Week In Startups is made possible by:

Paper: getpaper.ai/twist

G2i: G2i.co/twist

Northwest Registered Agent: www.northwestregisteredagent.com/twistdomain

Plaud: Plaud.ai/twist

Today’s show:

Odyssey co-founde... more

YouTube

This Week In Startups is made possible by:

Stripe: stripe.com/startups

Rippling: rippling.ai/twist

Northwest Registered Agent: www.northwestregisteredagent.com/twistdomain

Plaud: plaud.ai/twist

Today’s show:

Bina... more

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Key Facts

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Number of Listeners
Find out how many people listen to this podcast per episode and each month.

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Recent Guests

D.A. Wallach
Co-founder and general partner at Time BioVentures
Time BioVentures
Episode: Why a Do-Nothing Congress could be great for markets | E2359
Elana Gold
Investor focused on AI, infrastructure, space, robotics, defense and energy
Two Roads Capital
Episode: Why a Do-Nothing Congress could be great for markets | E2359
Tomasz Tunguz
Founder and general partner at Theory Ventures
Theory Ventures
Episode: Why a Do-Nothing Congress could be great for markets | E2359
Oliver Cameron
Co-founder and CEO of Odyssey, a company building world models for robots and AI agents
Odyssey
Episode: Odyssey CEO Oliver Cameron is 90% sure we live in a simulation | E2358
Jake Newfield
Hermetiq co-founder and CEO
Hermetiq
Episode: Binance Hacked $6.3B Stolen, DoorDash Buys Instacart For $17B, Jake Newfield from Hermetiq, + More!
Dave McClure
Managing partner at a venture capital firm focused on venture secondaries
Practical Venture Capital
Episode: Is AI the new cigarettes? Our VC panel digs into Anthropic’s S-1 | E2356
Ben Black
Co-founder and managing director of Akkadian Ventures and chief investment officer of Powerlaw Corp
Akkadian Ventures
Episode: Is AI the new cigarettes? Our VC panel digs into Anthropic’s S-1 | E2356
Amanda Bradford
Founder of The League, a dating app acquired by Match Group
The League
Episode: Pregame Your Launch Before Your App Exists (w/ Amanda Bradford) | E2355
Patrick Collison
Co-founder and CEO of Stripe
Stripe
Episode: Pregame Your Launch Before Your App Exists (w/ Amanda Bradford) | E2355

Hosts

Jason Calacanis
Host known for driving deep founder-focused conversations; frequently sets the agenda, challenges assumptions, and steers strategic discussions.
Lon Harris
Co-host and interviewer; contributes market context and synthesizes topics for scalable storytelling.
Alex Wilhelm
Host and discussion facilitator for Twist segments and startup insights; often introduces topics and guides conversation.

Reviews

4.3 out of 5 stars from 3.1k ratings
  • Honest feedback founders need

    The Oct 10 episode where 11 founders pitched Jason and Yuki Shirato of Techstars Tokyo at the Osaka event was packed with blunt, useful feedback on decks and problem selection. A great show for founders who want to hear how investors actually think.

    Podchaser
    5
    Sabrina Runbeck
    19 days ago
  • Long time fan

    At this point, in late 2026, it’s just This Week in AI. After spending a month straight only talking about OpenClaw, I started skipping episodes for the first time ever.

    I’ve been listening to TWiST for several years and have seen it go through changes, some good, some not so good. The show has evolved and pivoted over the years, so I will stay connected in the hope it does so again.

    Apple Podcasts
    3
    ProstCFC
    United Statesa month ago
  • Audio only option

    I really like this podcast and have been listening to it for more than a decade. But recent changes to the iPod version require me to download the video version. I just want the audio version so I can listen to it on the go. Recent changes that force me to download a 8GB video file to my iPhone is frustrating.

    Apple Podcasts
    1
    JSVentures
    Japan3 months ago
  • Alpaka bag is now $155

    Thanks to Ja Cal the Alpaka back is $155 not $133. Great episode.

    Apple Podcasts
    5
    Alaskariverguy
    United States5 months ago
  • 10min contents + 30min ads

    As title lol

    Apple Podcasts
    1
    Ruedhdhejej
    Taiwan6 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Shows high utility for founders and investors with practical startup playbooks.
Ad-heavy episodes sometimes detract from listening experience for some listeners.
Audience often praises founders'-first perspective and market savvy.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#33
United States/Technology
Apple Podcasts
#51
Canada/Technology
Apple Podcasts
#59
United Kingdom/Technology
Apple Podcasts
#55
Australia/Technology
Apple Podcasts
#137
Germany/Technology
Apple Podcasts
#147
Italy/Technology

Talking Points

Recent interactions between the hosts and their guests.

Binance Hacked $6.3B Stolen, DoorDash Buys Instacart For $17B, Jake Newfield from Hermetiq, + More!
Q: What's the question you get over and over again from investors here?
Jake says investors ask why AI labs would pay a small startup for Hermetiq rather than build the product themselves. He argues that the labs want to focus resources on their core work, such as building language models, and says the customer's recurring payments validate the need.
Binance Hacked $6.3B Stolen, DoorDash Buys Instacart For $17B, Jake Newfield from Hermetiq, + More!
Q: Does this go through and is this a monopoly risk to put DoorDash and Instacart together?
Jason expects the deal to proceed under the current regulatory climate and argues that measuring third-party grocery delivery alone leaves out competitors such as Amazon, Walmart, and grocery chains with their own delivery services. He also calls the purchase an overpay.
Odyssey CEO Oliver Cameron is 90% sure we live in a simulation | E2358
Q: How purely from visuals can robots and cars learn everything they need to know about our world and how matter moves through it?
Cameron says a world model learns by observing extensive video and predicting how physics and motion evolve, building broad knowledge that can be adapted to tasks with limited additional experience.
Odyssey CEO Oliver Cameron is 90% sure we live in a simulation | E2358
Q: What percentage are you convinced that we're in a simulation right now?
Oliver Cameron says he is 90% certain that reality is a very advanced simulation.
Why a Do-Nothing Congress could be great for markets | E2359
Q: Can the Dems actually find a middle ground here between being anti-capitalist, anti-progress, being decels, and getting economic growth?
Elana Gold says the country needs to embrace technology while showing how autonomous vehicles and robotics can improve access, reduce travel barriers and create new opportunities, even as people worry about job losses.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
Professions
Age Range
Household Income
Social Media Reach

Frequently Asked Questions About This Week in Startups

What is This Week in Startups about and what kind of topics does it cover?

A sharp-tanged look at the startup world, with conversations that thread through venture capital, product strategy, and market dynamics. Episodes frequently dissect how AI, data, and growth metrics reshape the SaaS landscape, featuring deep dives with founders, investors, and operators who share practical lessons on fundraising, go-to-market, and building resilient companies. Notable standouts include guests exploring frontier tech (robotics, quantum hardware, cellular agriculture) and live, candid takes on funding ecosystems, liquidity, and the evolving role of AI in startups. The show often balances founder-first interviews with roundtable VC analyses, and maintaining sponsor-friendly ad reads is a recurring, visible element. This mix mak... more

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Which podcasts are similar to This Week in Startups?

These podcasts share a similar audience with This Week in Startups:

1. This Week in AI
2. The a16z Show
3. All-In with Chamath, Jason, Sacks & Friedberg
4. The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch
5. BG2Pod with Brad Gerstner and Bill Gurley

How many episodes of This Week in Startups are there?

This Week in Startups launched 18 years ago and published 1499 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on This Week in Startups?

Recent guests on This Week in Startups include:

1. D.A. Wallach
2. Elana Gold
3. Tomasz Tunguz
4. Oliver Cameron
5. Jake Newfield
6. Dave McClure
7. Ben Black
8. Amanda Bradford

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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