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This Week in AI

Jason Calacanis
Artificial Intelligence
Openclaw
Open Source AI
Anthropic
Productivity
Automation
Gecko Robotics
Abridge
Hermes Agent
Education
Openai
Gemini 3.0
Ziosec
AI Security
Penetration Testing
Prompt Injection
AI Inference
Healthcare
China
Frontier AI

An experts-only AI podcast: Think the 'All In' podcast for AI. Jason + 3 CEO-level experts breaking down the news & trends.

PublishesWeeklyEpisodes30Founded7 months ago
Number of ListenersCategory
Technology

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Artwork for This Week in AI

Latest Episodes

This Week In Startups is made possible by:PaypalToday’s show:XBOW’s AI has held the top rank on the HackerOne leaderboard for more than a year. On TWiAI, founder Oege de Moor (who also built GitHub Copilot) tells us that no one’s infrastructure is tr... more

This Week In AI is made possible by:

PayPal - Pay zero processing fees on your first $100K in eligible PayPal payment volume. Learn more at paypal.launch.co

Today’s show:

*On “All In,” Gavin Baker said that Anthropic leadership privately believes ... more

This Week In AI is made possible by:

Paypal Open

Today’s show:

Anthropic’s new Claude watermark travels around any and all copy-and-pasted text. Is this a logical response to AI slop, or more overreach from those regulation-loving Europeans? The p... more

This Week In Startups is made possible by:

PAYPAL OPEN

Today’s show:

China’s Alibaba just dropped a 2.4 trillion parameter open weight model that the company claims only trails Anthropic’s flagship among the major frontier rivals. Of course, this ... more

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Recent Guests

Will Bryk
CEO and co-founder of EXA, developer-facing AI search for agents
EXA
Episode: Why Anthropic is watermarking every word Claude writes | E26
Josh Sirota
CEO and founder of Eragon, agentic operating system for enterprises
Eragon
Episode: Why Anthropic is watermarking every word Claude writes | E26
Kash Ali
Co-founder and CEO of Tax GPT, AI operating system for accountants
Tax GPT
Episode: Why Anthropic is watermarking every word Claude writes | E26
Eiso Kant
CTO and co-founder of Poolside AI
Poolside AI
Episode: Is open source AI really ahead of the frontier? 3 builders weigh in. | E25
Alex Cheema
Co-founder of EXO Labs
EXO Labs
Episode: Is open source AI really ahead of the frontier? 3 builders weigh in. | E25
Grant Lee
CEO, Gamma (AI presentation and visuals startup)
Gamma
Episode: Are we already in the Singularity? | E24
Anand Kannappan
CEO and co-founder, Patronus AI
Patronus AI
Episode: America already lost one AI race | TWiAI Ep 23
Ori Goshen
Co-CEO and co-founder, AI21 Labs
AI21 Labs
Episode: America already lost one AI race | TWiAI Ep 23
Sara Hooker
Co-founder and CEO, Adaption Labs
Adaption Labs
Episode: Grok 4.5 and GLM-5.2 kick off Token Price Wars | E22

Hosts

Jason Calacanis
Host of This Week in AI; regular participant in AI industry roundtables; known for founder-level perspectives on AI strategy and policy.
Lon Harris
Editorial Director and News Reader; co-host with focus on industry news, governance, and market implications.
Alex Wilhelm
Host focusing on AI business, policy, and market trends within the AI ecosystem.

Reviews

4.6 out of 5 stars from 9 ratings
  • Love the new show

    Can’t wait for things to get rolling!

    Apple Podcasts
    5
    NYElliot
    United States7 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Energy and pace keep the conversations engaging for executives.
Shows strong industry insights from founders and operators.
Quality of guests varies but generally high for enterprise-focused AI topics.
Guests provide practical perspectives on AI economics and governance.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#122
United States/Technology
Apple Podcasts
#178
United Kingdom/Technology
Apple Podcasts
#209
Germany/Technology
Apple Podcasts
#94
Israel/Technology
Apple Podcasts
#129
Japan/Technology
Apple Podcasts
#163
United Arab Emirates/Technology

Talking Points

Recent interactions between the hosts and their guests.

Mythos, Sonnet 5, GLM-5.2 Dominate the News Cycle | Episode 20
Q: Is there real regulatory concern for enterprises adopting GLM 5.2 and related technologies, or is this mostly chatter on social media?
There is genuine regulatory concern among hyperscalers and the administration, with participation in trusted access programs and a push for security and control; enterprises weigh cost, access, and security when choosing where to deploy models, including on-premise and managed services.
Mythos, Sonnet 5, GLM-5.2 Dominate the News Cycle | Episode 20
Q: Is the US AI policy reasonable and legible at this point, or am I incorrect in viewing it as insane?
The panel largely agrees that the policy is seen as insane by many, contributing to regulatory friction and allowing other actors to gain leverage in AI development; they also emphasize the role of open source models in enabling faster innovation, while seeking clearer rules and safer deployment.
America already lost one AI race | TWiAI Ep 23
Q: Should the market decide or should regulation intervene to protect frontier labs?
The panel emphasizes a balance: let the market drive innovation and cost efficiency, but be mindful of safeguards and strategic policies that prevent a collapse of domestic AI leadership, especially given geopolitical competition.
America already lost one AI race | TWiAI Ep 23
Q: What does it mean for America to win the AI race?
Winning means strengthening the underlying infrastructure and getting the most capable models into enterprise use, while maintaining competitive costs and preserving national leadership in AI hardware, software, and deployment at scale.
The Future of AI: Personal Agents, Taste & Private Data | Lin Qiao & Demi Guo | E9
Q: How do customers actually adopt this in terms of data and deployment—on their own hardware or via managed services?
Customers typically start with private data tuning and controlled deployment, then decide whether to run on their own hardware or rely on hosted services. Fireworks offers a spectrum of abstraction—from low-level control for hackers to high-level automation for non-AI specialists—so teams can incrementally adopt frontier capabilities while maintaining data sovereignty.

Audience Metrics

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Frequently Asked Questions About This Week in AI

What is This Week in AI about and what kind of topics does it cover?

A technology-forward, founder-led roundtable focused on AI industry dynamics, policy, open vs. closed models, and practical enterprise applications. Guests are typically CEOs, founders, and senior operators from AI, infrastructure, and enterprise tooling, offering hands-on perspectives on governance, cost, and deployment. The show often centers on regulatory trends, model stewardship, and the economics of running AI at scale, with frequent discussions about open-source vs. proprietary ecosystems, world models, and the intersection of AI with space, robotics, and enterprise workflows. Noteworthy is the panel-driven format that blends strategic critique with real-world use cases, making it valuable for leaders evaluating AI investments, partn... more

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Which podcasts are similar to This Week in AI?

These podcasts share a similar audience with This Week in AI:

1. This Week in Startups
2. All-In with Chamath, Jason, Sacks & Friedberg
3. The a16z Show
4. AI + a16z
5. Training Data

How many episodes of This Week in AI are there?

This Week in AI launched 7 months ago and published 30 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on This Week in AI?

Recent guests on This Week in AI include:

1. Will Bryk
2. Josh Sirota
3. Kash Ali
4. Eiso Kant
5. Alex Cheema
6. Grant Lee
7. Anand Kannappan
8. Ori Goshen

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