Rephonic
Artwork for Moonshots

Moonshots with Peter Diamandis

PHD Ventures
Artificial Intelligence
Longevity
Healthcare
Bitcoin
Openai
Robotics
Artificial General Intelligence
Elon Musk
China
Google
Entrepreneurship
Education
Quantum Computing
Humanoid Robots
Space Exploration
Mental Health
Spacex
Biotechnology
AGI
United States

Tracking the future of technology and how it impacts humanity. Named by Fortune as one of the “World’s 50 Greatest Leaders,” Peter H. Diamandis, MD, is a founder, investor, advisor, and best-selling author. Join Peter on his mission to uplift humanity through technology. Follow Peter on X - x.com/PeterDiamandis

PublishesTwice weeklyEpisodes264Founded4 years ago
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Business

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Artwork for Moonshots

Latest Episodes

In this episode, the mates discuss Opus 4.8, The OpenAI Foundation, Demis Hassabis' views on AGI, AI extremism on the rise, and more.

Get access to metatrends 10+ years before anyone else - qr.diamandis.com/metatrends

Peter H. Diamandis, MD... more

This episode is a sprawling Moonshots roundup with three big pillars: AI governance and religion, AI’s impact on jobs and entrepreneurship, and a moon/space-compute future centered on SpaceX, Starlink, and Tesla.

Education survey: Moonshots.com/surv... more

YouTube

This episode is a deep dive on the “organizational singularity”: how AI agents, AI-native workflows, and recursive self-improvement will restructure companies much faster than traditional hierarchy can adapt.

Get access to metatrends 10+ years befor... more

YouTube

In this episode, the Moonshot mates discuss SpaceX's record-breaking IPO filing and its growing ties to Anthropic, OpenAI's AI model disproving a decades-old Erdős conjecture in mathematics, and GPT-5.5 beating prediction markets at forecasting.

Get... more

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Accepts Guests
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Recent Guests

Andre Karpathy
Co-founder of OpenAI; later joined Anthropic
Anthropic
Episode: Google I/O 2026, Karpathy Joins Anthropic, and Cerebras’ $95B IPO | EP #256
Andrew Feldman
CEO of Cerebras Systems
Cerebras
Episode: Google I/O 2026, Karpathy Joins Anthropic, and Cerebras’ $95B IPO | EP #256
Dawn Musalem
Chief Medical Officer, Fountain Life
Fountain Life
Episode: Anthropic Partners With SpaceX AI, Leopold's $5.5B Bet, and the Singularity Economy | EP #255
Ray Kurzweil
Friend of the pod, guest at MIT event
Author/Inventor
Episode: Google's Record Quarter, the White House Intervenes, and GPT 5.5 Silently Matches Mythos | EP 254
Demis Hassabis
CEO of DeepMind
DeepMind
Episode: Demis Hassabis on AGI, Robots Scale Production, and Elon’s $1T Mars-Shot Comp | EP #253
David Sinclair
Leading longevity researcher, co-founder of Sinclair Lab
Life Biosciences / Sinclair Lab
Episode: David Sinclair on the Longevity Pill, Age Reversal Timelines, and Updated Protocols | EP #250
Sid Sibrandich
Founder of GitLab, discussed AI-driven medical breakthroughs
GitLab
Episode: Sam Altman’s Attack, Amazon vs. Starlink, and What Opus 4.7 Actually Means | #248
Mark Cuban
Entrepreneur and investor featured in discussion clips
Entrepreneur and investor
Episode: Elon Musk vs. Sam Altman, AI Job Loss, and OpenAI’s $852B Valuation | EP #247
Ben Lamm
CEO of Colossal
Colossal
Episode: How AI Is Bringing Extinct Animals Back (And What Comes Next) | Ben Lamm (Colossal) | EP #245

Host

Peter Diamandis
Host with a track record of leading conversations on exponential tech and future-orientated topics.

Reviews

4.7 out of 5 stars from 1.6k ratings
  • Wildly optimistic futurism

    I listen to show for pure entertainment but only in small doses. They like to talk about all the ways AI will make our lives easier in the future I but take a lot of it with a grain of truth. “Don’t save for retirement as money won’t be needed”, “Humanoids living in data centers built on the moon”, “Data centers will push energy costs to zero for everyone” and “Elon is the great visionary who will solve all our problems”. I wish I had this level of optimism and/or whatever they are smoking.

    Apple Podcasts
    3
    Always be questioning
    United States2 months ago
  • Must have pod

    Loved the new format of this pod, deep dives are so good, learned a lot. Appreciated your time & efforts.

    Apple Podcasts
    5
    Humanity & Peace
    Canada2 months ago
  • AI creates jobs IT Jobs

    Death of SaaS? A $15M Australian Company Swapped there HR app “Employment Hero" for AI in 4 Hours.

    We’ve all heard the doomsday predictions about AI and the job market. But for a $15 million Australian company (approx. $10M USD), the story isn't about redundancy—it's about a radical shift in how businesses are built and scaled.

    They didn't just tweak their workflow; they fired their HR software.

    The 4-Hour Software Revolution

    Using Anthropic’s latest code-generation tools, this small business m... more

    Apple Podcasts
    5
    GrillaBBQ
    Australia3 months ago
  • Enjoy the optimism. Beware the blind spots.

    I’ve become a regular listener to Moonshots. It’s a good place to tune in if you want to understand where technology is headed. The hosts seem genuinely enthusiastic and optimistic, which I appreciate.

    But the longer I’ve listened, the more a single, serious gap has become impossible to ignore.

    The running theme of “Abundance” is an appealing and optimistic framework, and in many ways very inspiring. The problem is that it functions more like a faith position than an argument. It doesn’t serio... more

    Apple Podcasts
    3
    benoftroy
    United States3 months ago
  • The most interesting and relevant podcast in my list today.

    I wish I had the time to listen and to relisten all the episodes.

    Podcast Addict
    5
    Frank Drebin
    4 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Some listeners critique production quality or pacing and desire tighter moderation.
A subset feels the discussions sometimes lean toward promotional or bubbles of Silicon Valley.
Positive endorsements of the show's optimism and insightful guests.
Many praise the breadth of topics from AI to longevity and its practical implications.
Listeners frequently cite high-quality guests and actionable, future-focused ideas.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

The Organizational Singularity: AI-Proof Your Company | EP #258
Q: How do you start moving a traditional company toward this new model?
Start at the edge by creating an AI-native digital twin of a workflow, spin off a separate edge entity to test and iterate, and gradually migrate workflows while de-risking the mothership. Use backcasting to envision the AI-native future and score the current organization on organizational drag and AI maturity.
The Organizational Singularity: AI-Proof Your Company | EP #258
Q: What is the Organizational Singularity and why is it necessary now?
The Organizational Singularity is a shift from hierarchical, human-centric organizations to AI-native, agent-driven structures with governance and recursive learning loops. It is necessary because AI and AGI will disrupt traditional business models quickly, and companies must retool or be disrupted.
Anthropic Partners With SpaceX AI, Leopold's $5.5B Bet, and the Singularity Economy | EP #255
Q: Which will end up bigger, consumer AI or enterprise AI?
Enterprise AI is expected to outpace consumer AI in the near to mid-term due to higher IT spend and the needs of business processes, with consumer use cases potentially becoming indistinguishable from enterprise as capabilities scale.
Demis Hassabis on AGI, Robots Scale Production, and Elon’s $1T Mars-Shot Comp | EP #253
Q: What is your view on whether AGI requires a major breakthrough?
Demis Hassabis argues there may not be a need for a singular breakthrough, with foundation models and improved world models potentially converging toward AGI, while others note that a definitive, universally agreed-upon definition and metrics for AGI remain elusive.
David Sinclair on the Longevity Pill, Age Reversal Timelines, and Updated Protocols | EP #250
Q: When might we see broad access to longevity therapies, and what are the barriers?
The goal is to scale from tissue-by-tissue to whole-body approaches as delivery methods improve, with price reduction through scale-up and alternative modalities, aiming for widespread access within a couple of decades.

Audience Metrics

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Frequently Asked Questions About Moonshots

What is Moonshots about and what kind of topics does it cover?

A high-velocity exploration of emerging technologies, AI, longevity, and how breakthrough science could reshape business and society. Episodes feature interviews with founders, researchers, and thinkers who offer optimistic yet pragmatic takes on the pace of innovation, its economic implications, and potential pathways to a better future. The show tends to connect technical advances to practical outcomes, from education and healthcare to productivity and global governance, often highlighting bold visions, scalable models, and the challenges of implementing rapid change. A few episodes stand out for their ambitious guest lineups and timely debates on policy, privacy, and the governance of powerful technologies, making it useful for listeners... more

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How many listeners does Moonshots get?

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What are the audience demographics for Moonshots?

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How many subscribers and views does Moonshots have?

To see how many followers or subscribers Moonshots has on Spotify and other platforms such as Castbox and Podcast Addict, simply upgrade your account. You'll also find viewership figures for their YouTube channel if they have one.

Which podcasts are similar to Moonshots?

These podcasts share a similar audience with Moonshots:

1. All-In with Chamath, Jason, Sacks & Friedberg
2. The a16z Show
3. The Pomp Podcast
4. Exponential Wisdom
5. No Priors: Artificial Intelligence | Technology | Startups

How many episodes of Moonshots are there?

Moonshots launched 4 years ago and published 264 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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Where can I see ratings and reviews for Moonshots?

Rephonic pulls ratings and reviews for Moonshots from multiple sources, including Spotify, Apple Podcasts, Castbox, and Podcast Addict.

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What guests have appeared on Moonshots?

Recent guests on Moonshots include:

1. Andre Karpathy
2. Andrew Feldman
3. Dawn Musalem
4. Ray Kurzweil
5. Demis Hassabis
6. David Sinclair
7. Sid Sibrandich
8. Mark Cuban

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