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The Stem Cell Report with Janet Rossant

ISSCR
Stem Cell Research
Lung Development
Stem Cells
Regenerative Medicine
Cell Differentiation
Parkinson's Disease
Aging
Pluripotent Stem Cells
Retinal Regeneration
Neurogenesis
Alveolar Cells
Vascular Biology
Epigenetics
Cell Therapy
Neuroscience
Dopaminergic Neurons
Stem Cell Reports
Spinal Cord Injury
Neural Development
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Stem cell science has catapulted to the forefront of biomedical research over the last decade, bringing with it the potential to transform human health and the treatment of devastating diseases and disorders. Janet Rossant, an internationally recognized stem cell pioneer and the dynamic editor-in-chief of Stem Cell Reports, explores basic discoveries in stem cell research and its application. Dr. ... more

PublishesMonthlyEpisodes40Founded4 years ago
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Artwork for The Stem Cell Report

Latest Episodes

Skeletal muscle is one of the most abundant tissues in the human body, representing approximately 40% of body weight. Under certain circumstances, skeletal muscle can be regenerated through satellite cells, a reservoir of quiescent muscle stem cells,... more

The potential of pluripotent stem cells and the ability to scale and differentiate them to generate large numbers of enriched cell populations has created new opportunities and approaches to treat human disease. Preclinical proof-of-principle data de... more

Parent-specific epigenetic marks (imprints) leading to parent-specific gene expression are crucial for normal growth and development, yet their mechanisms of establishment and maintenance are not fully understood. In humans, approximately 200 imprint... more

The mature lung in both humans and mice is highly vascularized, with approximately 30% of all cells being endothelial cells (ECs). The blood vessels have a physiological role in gas exchange within the tissue, but the vascular cells have additional r... more

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Recent Guests

Ngan Huang
Associate professor in the Department of Cardiothoracic Surgery at Stanford University and principal investigator at the Veterans Affairs Palo Alto Healthcare System.
Stanford University
Episode: Stem Cells in Space: Muscle Regeneration in Microgravity
Soochi Kim
Assistant professor in the Department of Biotechnology and Bioinformatics, Korea University.
Korea University
Episode: Stem Cells in Space: Muscle Regeneration in Microgravity
Clare Parish
Professor and Deputy Director of Science at the Florey Institute of Neuroscience and Mental Health, expert in stem cells and neurodevelopment.
Florey Institute of Neuroscience and Mental Health
Episode: Parkinson's Disease, Cell Therapy, and Exercise
Niamh Moriarty
Senior Research Fellow in the Stem Cells and Neurodevelopment Group at the Florey Institute, lead author of the recent study on exercise and neural grafts.
Florey Institute of Neuroscience and Mental Health
Episode: Parkinson's Disease, Cell Therapy, and Exercise
Thor Toynison
Associate professor in the Department of Developmental Biology and Center of Regenerative Medicine at Washington University School of Medicine
Washington University School of Medicine
Episode: Leaving an Imprint: The Function, Impact, and Detection of Epigenetic Marks
Gal Keshet
Graduate student in stem cell and genetic research at Hebrew University of Jerusalem
Hebrew University of Jerusalem
Episode: Leaving an Imprint: The Function, Impact, and Detection of Epigenetic Marks
Paolo Panza
New group leader at Justice Leibig University, Giesen, previously a postdoctoral fellow in Didier Stanier's lab.
Justice Leibig University, Giesen
Episode: Don’t Dull the SPARCL: The Lung Microvasculature and its Role in Development
Mingzha Zhu
Associate professor at the David Geffen School of Medicine, University of California, Los Angeles.
David Geffen School of Medicine, UCLA
Episode: Don’t Dull the SPARCL: The Lung Microvasculature and its Role in Development
Janet Rossant
Chief of Research Emeritus and Senior Scientist at the Hospital for Sick Children, and President and Scientific Director of the Gerdner Foundation
Gerdner Foundation
Episode: A Look Into the Future of Stem Cell Reports: A Conversation with Janet Rossant

Hosts

Janet Rossant
Editor-in-Chief of Stem Cell Reports and a globally recognized figure in stem cell research, she brings extensive experience and insights into the field.
Martin Pera
Former Editor-in-Chief of Stem Cell Reports, Martin has extensive experience in stem cell research and serves as a host, guiding discussions.

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Talking Points

Recent interactions between the hosts and their guests.

Parkinson's Disease, Cell Therapy, and Exercise
Q: Could you explain what an ectopic and a homotopic graft is and what the differences were?
Niamh elaborated on the placement of grafts, mentioning how ectopic grafts are implanted in the target region and homotopic in their native region, affecting recovery outcomes.
Parkinson's Disease, Cell Therapy, and Exercise
Q: Can you tell us about the differences, the pros and cons in those two populations?
Niamh explained the historical use of fetal-derived dopaminergic neurons and the shift towards pluripotent stem cells due to ethical concerns and scalability issues.
Leaving an Imprint: The Function, Impact, and Detection of Epigenetic Marks
Q: Gal, how did you get interested in stem cell research and imprinting?
Gal expressed that during his undergraduate studies, he was fascinated by how the epigenome orchestrates gene expression, leading him to pursue his studies in imprinting and stem cell research under a prominent professor in Israel.
Leaving an Imprint: The Function, Impact, and Detection of Epigenetic Marks
Q: Thor, what led to your interest in stem cell research, and how did that imprint you?
Thor shared that he developed an interest in stem cell research as an undergraduate at Harvard, where he was able to participate in embryonic stem cell research during its early days and recognized its transformative potential, leading him to pursue it as a career.
Don’t Dull the SPARCL: The Lung Microvasculature and its Role in Development
Q: Mingzha, your website describes the goal of your lab as developing novel therapies for regeneration.
Mingzha discusses how her interest in regenerative medicine began during her medical school internship.

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Frequently Asked Questions About The Stem Cell Report

What is The Stem Cell Report about and what kind of topics does it cover?

Featuring discussions that aim to connect scientific advances in stem cell research with their practical applications, a notable highlight is the focus on the relationship between stem cell science and various disease treatments. The conversations often include esteemed researchers and experts sharing insights from their own work, particularly in fields like neuroscience, regenerative medicine, and the impact of exercise on stem cell therapies. Unique aspects include discussions on epigenetics, modeling neurological diseases, and the importance of mentorship in the scientific community, which provide listeners with a comprehensive view of current trends and research challenges in the field of stem cells and their potential for transformativ... more

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Which podcasts are similar to The Stem Cell Report?

These podcasts share a similar audience with The Stem Cell Report:

1. The Stem Cell Podcast
2. NEJM This Week
3. Nature Podcast
4. The Readout Loud
5. The Daily

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The Stem Cell Report launched 4 years ago and published 40 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Stem Cell Report?

Recent guests on The Stem Cell Report include:

1. Ngan Huang
2. Soochi Kim
3. Clare Parish
4. Niamh Moriarty
5. Thor Toynison
6. Gal Keshet
7. Paolo Panza
8. Mingzha Zhu

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