The Genetics Podcast

Sano Genetics

Gene Therapy

Genomics

Precision Medicine

Genetics

Genetic Testing

Clinical Trials

Alzheimer's Disease

Rare Diseases

Sano Genetics

Biotechnology

Aging

Drug Discovery

UK Biobank

Personalized Medicine

FDA

Artificial Intelligence

Neurodevelopmental Disorders

Breast Cancer

Neurodegenerative Diseases

Parkinson's Disease

Exploring all things genetics. Dr Patrick Short, University of Cambridge alumnus and CEO of Sano Genetics, analyses the science, interviews the experts, and discusses the latest findings and breakthroughs in genetic research. To find out more about Sano Genetics and its mission to accelerate the future of precision medicine visit: www.sanogenetics.com

163 ratings

Publishes	Weekly	Episodes	256	Founded	7 years ago
Number of Listeners		Categories	Natural SciencesScience

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Latest Episodes

EP 256: Cutting through the AI hype in drug discovery with Dave Hallett of Recursion

This week on The Genetics Podcast, Patrick is joined by Dr. David Hallett, Chief Scientific Officer at Recursion. They discuss the biggest shifts in drug discovery over Dave's three-decade career, where AI is genuinely transforming the field today ve... more

10 Sep 2026 • 40 min

YouTube

EP 255: Turning long-read sequencing into a routine part of clinical care with Danny Miller of the University of Washington

This week on The Genetics Podcast, Patrick is joined by Dr. Danny Miller, Assistant Professor of Pediatrics and of Laboratory Medicine and Pathology at the University of Washington and Attending Physician at Seattle Children's Hospital. They discuss ... more

3 Sep 2026 • 36 min

YouTube

EP 254: Triangulating genetic evidence and dodging bias to pick winning drug targets with Brent Richards of 5 Prime Sciences

This week on The Genetics Podcast, Patrick is joined by Dr. Brent Richards, CEO and Founder of 5 Prime Sciences and Professor of Human Genetics, Epidemiology, and Medicine at McGill University. They discuss how to triangulate different types of genet... more

27 Aug 2026 • 41 min • Most popular

YouTube

EP 253: The genetics of brain size, growth, and aging with Andrew Jackson of the University of Edinburgh

This week on The Genetics Podcast, Patrick is joined by Dr. Andrew Jackson, Programme Leader at the MRC Human Genetics Unit at the University of Edinburgh. They discuss how his lab discovered that gain-of-function DNMT3A mutations cause both microcep... more

20 Aug 2026 • 37 min

YouTube

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Recent Guests

Dave Hallett

Chief Scientific Officer at Recursion

Recursion

Episode: EP 256: Cutting through the AI hype in drug discovery with Dave Hallett of Recursion

Brent Richards

Professor of Medicine and Human Genetics at McGill University and CEO of 5PrimeSciences

McGill University; 5PrimeSciences

Episode: EP 254: Triangulating genetic evidence and dodging bias to pick winning drug targets with Brent Richards of 5 Prime Sciences

Andrew Jackson

Professor, MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh

University of Edinburgh

Episode: EP 253: The genetics of brain size, growth, and aging with Andrew Jackson of the University of Edinburgh

Stevie Ringel

Founder and CEO of Nome Therapeutics; founder of the Kizuna Foundation

Nome Therapeutics / Kizuna Foundation

Episode: EP 252: The diagnosis that became a mission to cure rare disease: Advancing genetic medicine using AI with Stevie Ringel of Nome

Jagesh Shah

Chief Scientific Officer at Mirai Bio

Mirai Bio

Episode: EP 251: Cracking the delivery barrier in genetic medicine with Jagesh Shah of Mirai Bio

Carl Anderson

Head of the Human Genetics Programme, Wellcome Sanger Institute

Wellcome Sanger Institute

Episode: EP 249: Building the world's most detailed genetic map of inflammatory bowel disease with Carl Anderson of the Wellcome Sanger Institute

Pradeep Natarajan

Preventive Cardiologist and Cardiovascular Geneticist at Mass General Hospital

Mass General Hospital

Episode: EP 248: The blood mutations rewriting cardiovascular risk: Clonal hematopoiesis and polygenic risk with Pradeep Natarajan of Massachusetts General Hospital

Christopher Walsh

Bullard Professor of Pediatrics and Neurology at Harvard Medical School; Chief of Genetics and Genomics at Boston Children's Hospital; HHMI Investigator

Harvard Medical School; Boston Children's Hospital; Howard Hughes Medical Institute

Episode: EP 247: Why neurons accumulate mutations like clockwork: Somatic mosaicism and neurodegeneration with Christopher Walsh of Boston Children's Hospital

Yentli Soto Albrecht

MD PhD trainee, carrier of C9orf72 expansion, focused on accelerating cure research

CureC9 (biorepository initiatives with BrainX cell)

Episode: EP 246: Turning a fatal diagnosis into a cure strategy: Accelerating C9orf72 ALS research with Yentli Soto Albrecht of CureC9

Host

Patrick Short

Host of The Genetics Podcast (Sano Genetics), focuses on genetics, translational science, and the biotech landscape.

Reviews

4.9 out of 5 stars from 163 ratings

Great Experience!
Thank you for the opportunity to share our story from a parent led perspective about finding treatments for Usher syndrome. Patrick was an amazing host.
Apple Podcasts
5
Jp knows
United States10 months ago
Love the solo episode!
Super informative. More please!
Apple Podcasts
5
whirlaway25
United Statesa year ago
Smart, thoughtful, and always worth a listen
The Genetics Podcast consistently delivers engaging, well-researched conversations with leading scientists and innovators. It is one of the best ways to stay informed about the discoveries shaping the field of genetics
Apple Podcasts
5
moyavie
United Statesa year ago
Review
Fascinating and awesome!! Thanks!
Apple Podcasts
5
Polowonder
United Statesa year ago
Super interesting content
Great to see where precision medicine is heading and hear more about the companies that are working on new therapies
Apple Podcasts
5
shwkdk
United Kingdom2 years ago

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Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

The host keeps discussions grounded and engaging for both scientists and patients.

Guests consistently bring cutting-edge insights from academia and industry.

Listeners appreciate accessible explanations of complex genetics topics.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts	#56	United States/Science/Natural Sciences
Apple Podcasts	#58	United Kingdom/Science/Natural Sciences
Apple Podcasts	#134	Canada/Science/Natural Sciences
Apple Podcasts	#55	France/Science/Natural Sciences
Apple Podcasts	#102	Australia/Science/Natural Sciences
Apple Podcasts	#112	Italy/Science/Natural Sciences

Talking Points

Recent interactions between the hosts and their guests.

EP 254: Triangulating genetic evidence and dodging bias to pick winning drug targets with Brent Richards of 5 Prime Sciences

Q: Do you have a sense of how to weigh different types of genetic evidence when deciding which targets to pursue?

Yes. The approach is to triangulate across multiple, orthogonal lines of evidence so that biases in one line are countered by others. When different methods converge on the same direction and magnitude of effect, confidence in the target increases.

EP 256: Cutting through the AI hype in drug discovery with Dave Hallett of Recursion

Q: What skills should the next generation of scientists bring to thrive in this space?

Develop domain expertise across biology, chemistry, and computation, be fluent in data science tools, understand assay noise, and learn to balance skepticism with curiosity—always verify AI-driven hypotheses with real experimental data.

EP 256: Cutting through the AI hype in drug discovery with Dave Hallett of Recursion

Q: What data and infrastructure are essential to support reliable AI-driven drug discovery?

Reliable, disease-relevant data is critical, including perturbational maps and orthogonal validation in multiple models; having robust experimental infrastructure and access to diverse data sets is essential to trust the models and translate insights into therapies.

EP 256: Cutting through the AI hype in drug discovery with Dave Hallett of Recursion

Q: Where is AI really fundamentally changing what you do, and where do you see it not yet delivering on promises?

AI is enhancing data analysis, search, and visualization, and accelerating iterative optimization, but it's not replacing experimental biology or the need for clinical validation; the practical gains come from faster, data-driven hypothesis testing and smarter trial design.

EP 252: The diagnosis that became a mission to cure rare disease: Advancing genetic medicine using AI with Stevie Ringel of Nome

Q: How does Nome balance helping one patient versus groups of patients, and what does that mean for your business model?

Nome serves both single-patient needs and small patient groups. We focus on scalable processes and AI-enabled workflows to deliver personalized medicine at scale, leveraging foundations that own the programs and potential PRVs to broaden the customer base. The model is about sustainability through tech-enabled services rather than a single molecule, which also helps align capital with the mission.

Audience Metrics

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Frequently Asked Questions About The Genetics Podcast

What is The Genetics Podcast about and what kind of topics does it cover?

Across recent episodes, the show centers on cutting-edge genetics, from rare disease therapy development and AI-enabled drug discovery to advances in gene delivery, somatic mutations, and precision medicine. Conversations frequently feature researchers, clinicians, and biotech leaders discussing mechanisms, translational challenges, regulatory pathways, and the business realities of bringing genetic therapies to patients. Notable threads include patient-centric approaches, scalable delivery platforms, data sharing and collaboration, and the evolving regulatory and manufacturing landscapes shaping next-gen genetic medicines. The program often blends technical depth with practical storytelling, helping listeners understand how scientific adva... more

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Which podcasts are similar to The Genetics Podcast?

These podcasts share a similar audience with The Genetics Podcast:

1. The Readout Loud
2. Biotech Hangout
3. BioCentury This Week
4. DNA Today: A Genetics Podcast
5. Nature Podcast

How many episodes of The Genetics Podcast are there?

The Genetics Podcast launched 7 years ago and published 256 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Genetics Podcast?

Recent guests on The Genetics Podcast include:

1. Dave Hallett
2. Brent Richards
3. Andrew Jackson
4. Stevie Ringel
5. Jagesh Shah
6. Carl Anderson
7. Pradeep Natarajan
8. Christopher Walsh

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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