The Genetics Podcast

Sano Genetics

Gene Therapy

Genomics

Precision Medicine

Genetics

Genetic Testing

Clinical Trials

Alzheimer's Disease

Rare Diseases

Sano Genetics

Aging

Biotechnology

Drug Discovery

UK Biobank

Personalized Medicine

FDA

Artificial Intelligence

Neurodevelopmental Disorders

Breast Cancer

Neurodegenerative Diseases

Parkinson's Disease

Exploring all things genetics. Dr Patrick Short, University of Cambridge alumnus and CEO of Sano Genetics, analyses the science, interviews the experts, and discusses the latest findings and breakthroughs in genetic research. To find out more about Sano Genetics and its mission to accelerate the future of precision medicine visit: www.sanogenetics.com

170 ratings

Publishes	Weekly	Episodes	262	Founded	7 years ago
Number of Listeners		Categories	Natural SciencesScience

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Latest Episodes

EP 262: The genetic drivers of hemochromatosis, drug response, and multimorbidity with Luke Pilling of the University of Exeter

This week on The Genetics Podcast, Patrick is joined by Dr. Luke Pilling, Senior Lecturer in Genetic Epidemiology at the University of Exeter. They discuss hemochromatosis and the case for earlier diagnosis, and the genetic drivers of multimorbidity,... more

22 Oct 2026 • 38 min • Most popular

YouTube

EP 261: Inside the virtual biotech staffed by AI agents with James Zou of Stanford University

This week on The Genetics Podcast, Patrick is joined by Dr. James Zou, Associate Professor of Biomedical Data Science at Stanford University. They discuss the concept of virtual biotechs and how AI agents link single cell data to clinical trial succe... more

15 Oct 2026 • 36 min • Popular

YouTube

EP 260: How AI is reshaping genomics, disease prediction, and biosecurity with Jeffrey Barrett of the University of Helsinki

This week on The Genetics Podcast, Patrick is joined by Dr. Jeffrey Barrett, Group Leader at the Ellis Institute Finland and the University of Helsinki. They discuss using AI and federated biobank data to stratify common chronic diseases, how LLMs re... more

8 Oct 2026 • 45 min

YouTube

EP 259: A patient community driving awareness and research for Danon disease with Jenny Hsieh of the Danon Foundation

Summary

This week on The Genetics Podcast, Patrick is joined by Jenny Hsieh, Co-Founder and President of the Danon Foundation. They discuss how Danon disease affects males and females, why it is so often misdiagnosed, the current therapy landscape a... more

1 Oct 2026 • 38 min

YouTube

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Recent Guests

James Zou

Associate Professor of Biomedical Data Science at Stanford University

Stanford University

Episode: EP 261: Inside the virtual biotech staffed by AI agents with James Zou of Stanford University

Jeffrey Barrett

Professor of Computational Predictive Medicine, University of Helsinki and Ellis Institute, Finland

University of Helsinki; Ellis Institute

Episode: EP 260: How AI is reshaping genomics, disease prediction, and biosecurity with Jeffrey Barrett of the University of Helsinki

Jenny Hsieh

Co-founder and president of the Danon Foundation

Danon Foundation

Episode: EP 259: A patient community driving awareness and research for Danon disease with Jenny Hsieh of the Danon Foundation

Inigo Martincorena

Group leader at the Wellcome Sanger Institute

Wellcome Sanger Institute

Episode: EP 258: The mutations hiding in healthy tissues with Inigo Martincorena of the Wellcome Sanger Institute

Marleah Dean Kruzel

Professor of Communication at the University of South Florida

University of South Florida

Episode: EP 257: Managing hereditary cancer risk and medical uncertainty with Marleah Dean Kruzel of the University of South Florida

Dave Hallett

Chief Scientific Officer at Recursion

Recursion

Episode: EP 256: Cutting through the AI hype in drug discovery with Dave Hallett of Recursion

Danny E. Miller

Physician-scientist, assistant professor in Pediatrics and Genetic Medicine

University of Washington

Episode: EP 255: Turning long-read sequencing into a routine part of clinical care with Danny Miller of the University of Washington

Brent Richards

Professor of Medicine and Human Genetics at McGill University and CEO of 5PrimeSciences

McGill University; 5PrimeSciences

Episode: EP 254: Triangulating genetic evidence and dodging bias to pick winning drug targets with Brent Richards of 5 Prime Sciences

Andrew Jackson

Professor, MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh

University of Edinburgh

Episode: EP 253: The genetics of brain size, growth, and aging with Andrew Jackson of the University of Edinburgh

Host

Patrick Short

Host of The Genetics Podcast (Sano Genetics), focuses on genetics, translational science, and the biotech landscape.

Reviews

4.9 out of 5 stars from 170 ratings

Great Experience!
Thank you for the opportunity to share our story from a parent led perspective about finding treatments for Usher syndrome. Patrick was an amazing host.
Apple Podcasts
5
Jp knows
United Statesa year ago
Love the solo episode!
Super informative. More please!
Apple Podcasts
5
whirlaway25
United Statesa year ago
Smart, thoughtful, and always worth a listen
The Genetics Podcast consistently delivers engaging, well-researched conversations with leading scientists and innovators. It is one of the best ways to stay informed about the discoveries shaping the field of genetics
Apple Podcasts
5
moyavie
United Statesa year ago
Review
Fascinating and awesome!! Thanks!
Apple Podcasts
5
Polowonder
United States2 years ago
Super interesting content
Great to see where precision medicine is heading and hear more about the companies that are working on new therapies
Apple Podcasts
5
shwkdk
United Kingdom2 years ago

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Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

The host keeps discussions grounded and engaging for both scientists and patients.

Guests consistently bring cutting-edge insights from academia and industry.

Listeners appreciate accessible explanations of complex genetics topics.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts	#65	United States/Science/Natural Sciences
Apple Podcasts	#58	United Kingdom/Science/Natural Sciences
Apple Podcasts	#133	Canada/Science/Natural Sciences
Apple Podcasts	#16	Italy/Science/Natural Sciences
Apple Podcasts	#36	France/Science/Natural Sciences
Apple Podcasts	#78	Australia/Science/Natural Sciences

Talking Points

Recent interactions between the hosts and their guests.

EP 261: Inside the virtual biotech staffed by AI agents with James Zou of Stanford University

Q: Where do you see the impact coming first? Is it imaging? Is it early risk detection in clinical data plus other biomarkers?

Zou points to clinical imaging tools such as EchoNet and physiological data from sleep recordings as promising applications. He describes using sleep signals to predict disease risk, transferring models trained on sleep-lab data to consumer wearables, and combining measurements across organs to improve predictions.

EP 261: Inside the virtual biotech staffed by AI agents with James Zou of Stanford University

Q: Could you just talk about the paper for those who aren't familiar, and a little bit about some of the key things that you found and what surprised you from the results?

Zou explains that the virtual biotech uses teams of specialized AI agents to emulate drug discovery organizations. Its agents analyzed past trials and found that targets supported by single-cell evidence were about 48 percent more likely to reach the market than comparable targets without that support.

EP 260: How AI is reshaping genomics, disease prediction, and biosecurity with Jeffrey Barrett of the University of Helsinki

Q: How do you think about breaking down the problem of using AI to predict and stratify disease across large datasets?

The approach combines integrating multiple omics data types with modern AI models while recognizing data access constraints, advocating for federated setups to enable learning across biobanks without exposing individual data, and focusing on molecular subtypes to improve targeted interventions.

EP 257: Managing hereditary cancer risk and medical uncertainty with Marleah Dean Kruzel of the University of South Florida

Q: How should healthcare systems adapt as more people learn about their genetic risks?

Healthcare should move beyond the initial disclosure to lifespan-oriented support, including psychosocial coping resources, family communication guidance, and co-design of tools with patients so information translates into real-world actions, not just data. This means empowering patients through ongoing support rather than treating genetics as a single encounter.

EP 257: Managing hereditary cancer risk and medical uncertainty with Marleah Dean Kruzel of the University of South Florida

Q: What are the key communication challenges when discussing genetic risk with family members, and how can people navigate them?

Communication is not a one-time event; it requires ongoing dialogue, follow-ups, and sensitivity to how relatives might react differently. Female relatives often bear a larger responsibility for disclosure. It's important to provide space for processing, reconnect after initial disclosure, and use shared decision-making with clinicians to guide conversations.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About The Genetics Podcast

What is The Genetics Podcast about and what kind of topics does it cover?

Across recent episodes, the show centers on cutting-edge genetics, from rare disease therapy development and AI-enabled drug discovery to advances in gene delivery, somatic mutations, and precision medicine. Conversations frequently feature researchers, clinicians, and biotech leaders discussing mechanisms, translational challenges, regulatory pathways, and the business realities of bringing genetic therapies to patients. Notable threads include patient-centric approaches, scalable delivery platforms, data sharing and collaboration, and the evolving regulatory and manufacturing landscapes shaping next-gen genetic medicines. The program often blends technical depth with practical storytelling, helping listeners understand how scientific adva... more

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Which podcasts are similar to The Genetics Podcast?

These podcasts share a similar audience with The Genetics Podcast:

1. The Long Run with Luke Timmerman
2. Biotech Hangout
3. The Readout Loud
4. BioCentury This Week
5. Nature Podcast

How many episodes of The Genetics Podcast are there?

The Genetics Podcast launched 7 years ago and published 262 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Genetics Podcast?

Recent guests on The Genetics Podcast include:

1. James Zou
2. Jeffrey Barrett
3. Jenny Hsieh
4. Inigo Martincorena
5. Marleah Dean Kruzel
6. Dave Hallett
7. Danny E. Miller
8. Brent Richards

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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