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Microdose U - Psilocybin Microdosing for Depression and Anxiety

Dr. David M. Madow
Microdosing
Mental Health
Psilocybin
Anxiety
Depression
Magic Mushrooms
Patreon
LSD
Women's Health
Psychedelics
Microdose U
Perimenopause
PTSD
Meditation
Ssris
Mindfulness
Personal Growth
Self-Care
Menopause
Microdosing Psilocybin

My name is Dr. David Madow, and I’m the founder and host of Microdose U, a podcast focused on psilocybin microdosing for depression, anxiety, PTSD, and overall mental health. Not long ago, I was barely hanging on. Daily life was filled with fatigue, anxiety, depression, and a complete lack of motivation. I tried medications, psychotherapy, meditation, yoga, and everything else I was told might hel... more

PublishesDailyEpisodes488Founded5 years ago
Number of ListenersCategories
Mental HealthAlternative HealthHealth & Fitness

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Artwork for Microdose U

Latest Episodes

If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON

This is the #1 way to go deeper with Microdose U. Join our private communit... more

If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON

This is the #1 way to go deeper with Microdose U. Join our private communit... more

If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON

This is the #1 way to go deeper with Microdose U. Join our private communit... more

If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON

This is the #1 way to go deeper with Microdose U. Join our private communit... more

Key Facts

Contact Information
Podcast Host
Number of Listeners
Find out how many people listen to this podcast per episode and each month.

Similar Podcasts

Recent Guests

Mark A Jackson
Retired and living in the Philippines; provided a video tip on anxiety relief
Episode: Day 15 – Marky Mark
River D. Knight
Guest host answering questions about microdosing psilocybin
Microdose U
Episode: The Five BEST Microdosing Questions Ever Asked | 2026 Ep18
River Denyte
Guest who took over the studio segment
Healthcare/psychedelics field
Episode: I Microdosed Magic Mushrooms For Five Years | 2026 Ep14
River Knight
Patreon supporter and first-time podcast guest who reads a fan letter and discusses the Patreon community
Patreon community member
Episode: Lost on Mt Olympus | 2026 Ep12
Mark Jackson
Individual who moved to the Philippines to start over
Pembroke, North Carolina resident
Episode: Mark’s Magic Mushroom – Moved to the Philippines to Start Over | 2026 Ep11
Dr. Denise Morett
Doctor of psychology and expert in plant medicines, specifically microdosing psychedelics.
Microdose U
Episode: SPECIAL – Psilocybin For Perimenopause and Women’s Health featuring Dr. Denise
Ryan Estes
CEO of Kitcaster and host of AI for Founders podcast
Kitcaster
Episode: A Night With Ayahuasca
Jordan Power
Singer-songwriter and former marketing firm owner
Grey Smoke Media
Episode: He Died Then Music Brought Him Back – Jordan Power
Nico Dosenbach
Associate Professor of Neurology at Washington University School of Medicine
Washington University School of Medicine
Episode: Scientist Takes High Dose of Psilocybin Then Gets Into an MRI Machine to Scan His Own Brain

Hosts

Dr. Denise
Host of Microdose U, Microdose U
Dr. Dave
Co-host mentioned as a host; participant in Microdose U discussions
Dr. David Madow
Host of Microdose U; central figure in the show

Reviews

4.9 out of 5 stars from 591 ratings
  • Meh

    Constantly shilling his patreon for half the episode. Doesn’t share much helpful info. The questions he gets are answered lazily.

    Apple Podcasts
    1
    Torps3993
    United Statesa year ago
  • The Best Podcast Ever

    Incredible Podcast – A Must-Listen!

    David brings the perfect mix of insight, authenticity, and entertainment. Every episode feels like a conversation with a close friend who just gets it. Whether he’s dropping wisdom, sharing real stories, or interviewing amazing guests, there’s always something valuable to take away. Keep up the amazing work, David—this show is truly next level!

    Apple Podcasts
    5
    mattywblue
    United Statesa year ago
  • Thanks 🙏🏻

    Thank you for the excellent and informative podcast 🙏🏻

    Apple Podcasts
    5
    DAV.ROW
    South Africa2 years ago
  • OCD and psilocybin

    Hi Dr Dave. Psychotherapist and psilocybin researcher here. OCD & other anxiety disorders tend to need much higher doses to make deep neurological changes that you addressed in this episode. Microdosing does not have the sufficient research as higher doses do. In the literature, psilocybin needs to be in the 20-50 mg range to make deep changes in neuroplasticity. This probably translates to somewhere in the range of 3-5 grams of dried fruit (depends on strength of strain). It’s not ... more

    Apple Podcasts
    5
    Jnewmark44
    United States2 years ago
  • Change

    Thank you Nakama.

    Your Hawaii broadcast made me think a lot…I’m going to listen to this broadcast again and give it a lot of thought.

    It really touched home for me.

    As I looked at the clock, the microwave said 515 so I looked up the number.

    As the meaning of angel number 515 is linked to personal freedom, major life changes, and the fact that you have the power to create your own reality, these can be the beautiful energies circling this triptych of digits.

    Thank you, Dave. I look forward to... more

    Apple Podcasts
    5
    Bewegirl
    United States2 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Many appreciate the community support and Patreon-driven deep-dives.
Listeners praise the host's warmth and accessible delivery.
Some criticism notes a focus on Patreon content and perceived promotional segments.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Day 6 – The Psychologist
Q: What did Adam say about anxiety?
Adam suggested that anxiety can be addressed through daily movement and outdoor activity, and by using breathing techniques to regulate stress levels.
Day 4 – The 81 Year Old Man in the Restaurant
Q: Tell me how you deal with anxiety and stay happy, Mark.
Mark explains his technique of boxing off anxious thoughts into a container to revisit later, emphasizing it as a practical, repeatable approach rather than a guaranteed cure.
The Case for Low-Dose Psilocybin in Mental Health
Q: Don't I need to do higher doses for psychedelics to help heal physical and psychological issues?
The host explains that higher macrodoses are not necessary for healing, are often contraindicated, and that real-world microdosing data shows meaningful benefits for many people without needing to reach trippy, high-dose levels.
How to Feel Calmer
Q: What do you mean that the source of pain is also the source of healing?
Pain signals imbalance and, rather than suppressing it, you should explore what it's signaling, because that exploration can guide you toward healing and growth.
Mark’s Magic Mushroom – Moved to the Philippines to Start Over | 2026 Ep11
Q: What prompted you to move to the Philippines at 63?
A combination of worsening health, caregiving responsibilities at home, and a deep longing for happiness and a life that felt possible beyond the constraints of the U.S. environment. The Philippines offered warmth, community, and a sense of renewal that aligned with his desire to live more fully.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
Professions
Age Range
Household Income
Social Media Reach

Frequently Asked Questions About Microdose U

What is Microdose U about and what kind of topics does it cover?

This show centers on psilocybin microdosing as a tool for mental health, with a practical, experience-driven approach. Episodes frequently cover dosing variability, safety, harm-reduction, lifestyle factors, and community support, often featuring listener testimonials and real-world case examples. The host leans into personal storytelling and accessible takeaways, while inviting expert and community perspectives through Patreon discussions and guest conversations. A notable strength is the blend of clinical curiosity with lived experience, creating a relatable, supportive space for listeners exploring microdosing as part of overall wellbeing. The format often emphasizes actionable guidance, safety, and ongoing education rather than sensatio... more

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Which podcasts are similar to Microdose U?

These podcasts share a similar audience with Microdose U:

1. The Psychedelic Podcast
2. Microdose U - Psilocybin Microdosing for Depression and Anxiety
3. Huberman Lab
4. The Mel Robbins Podcast
5. The Ultimate Human with Gary Brecka

How many episodes of Microdose U are there?

Microdose U launched 5 years ago and published 488 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact Microdose U?

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What guests have appeared on Microdose U?

Recent guests on Microdose U include:

1. Mark A Jackson
2. River D. Knight
3. River Denyte
4. River Knight
5. Mark Jackson
6. Dr. Denise Morett
7. Ryan Estes
8. Jordan Power

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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