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Microdose U - Psilocybin Microdosing for Depression and Anxiety

Dr. David M. Madow
Microdosing
Mental Health
Psilocybin
Depression
Anxiety
Magic Mushrooms
Women's Health
LSD
Psychedelics
Patreon
PTSD
Microdosing Psilocybin
Perimenopause
Microdose U
Meditation
Mindfulness
Personal Growth
Webinar
Spirituality
Self-Care

My name is Dr. David Madow, and I’m the founder and host of Microdose U, a podcast focused on psilocybin microdosing for depression, anxiety, PTSD, and overall mental health. Not long ago, I was barely hanging on. Daily life was filled with fatigue, anxiety, depression, and a complete lack of motivation. I tried medications, psychotherapy, meditation, yoga, and everything else I was told might hel... more

PublishesTwice weeklyEpisodes488Founded5 years ago
Number of ListenersCategories
Mental HealthAlternative HealthHealth & Fitness

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Artwork for Microdose U

Latest Episodes

Welcome to Microdose U! Thanks for being here! You are about to change your life!!!

In order to get the most out of the show, please do these very important things below:

1. PATREON!!! We discuss things there that we cannot discuss anywhere else!... more

Welcome to Microdose U! Thanks for being here! You are about to change your life!!!

In order to get the most out of the show, please do these very important things below:

1. PATREON!!! We discuss things there that we cannot discuss anywhere else!... more

Welcome to Microdose U! Thanks for being here! You are about to change your life!!!!!!

In order to get the most out of the show, please do these very important things below:

1. PATREON!!! We discuss things there that we cannot discuss anywhere el... more

Welcome to Microdose U! Thanks for being here! You are about to change your life!!!

In order to get the most out of the show, please do these very important things below:

1. PATREON!!! We discuss things there that we cannot discuss anywhere else!... more

Key Facts

Contact Information
Podcast Host
Number of Listeners
Find out how many people listen to this podcast per episode and each month.

Similar Podcasts

Recent Guests

River D. Knight
Guest host answering questions about microdosing psilocybin
Microdose U
Episode: The Five BEST Microdosing Questions Ever Asked | 2026 Ep18
River Denyte
Guest who took over the studio segment
Healthcare/psychedelics field
Episode: I Microdosed Magic Mushrooms For Five Years | 2026 Ep14
River Knight
Patreon supporter and first-time podcast guest who reads a fan letter and discusses the Patreon community
Patreon community member
Episode: Lost on Mt Olympus | 2026 Ep12
Mark Jackson
Individual who moved to the Philippines to start over
Pembroke, North Carolina resident
Episode: Mark’s Magic Mushroom – Moved to the Philippines to Start Over | 2026 Ep11
Ryan Estes
CEO of Kitcaster and host of AI for Founders podcast
Kitcaster
Episode: A Night With Ayahuasca
Jordan Power
Singer-songwriter and former marketing firm owner
Grey Smoke Media
Episode: He Died Then Music Brought Him Back – Jordan Power
Nico Dosenbach
Associate Professor of Neurology at Washington University School of Medicine
Washington University School of Medicine
Episode: Scientist Takes High Dose of Psilocybin Then Gets Into an MRI Machine to Scan His Own Brain
Dr. Uchi Odiatu
Dentist, nutrition expert, and speaker
Episode: How Depession and Anxiety Are Related to Gut Health
Jake Stanisci
Local Salt Lake City Psychedelic Facilitator
Sol Passage, Psychedelic Passage
Episode: The Psychedelic Facilitator

Hosts

Dr. Denise
Host of Microdose U; affiliated with Microdose U; contributor to education on microdosing and mental health.
Dr. Dave
Co-host; focuses on microdosing education, patient experience, and community building.

Reviews

4.9 out of 5 stars from 585 ratings
  • Meh

    Constantly shilling his patreon for half the episode. Doesn’t share much helpful info. The questions he gets are answered lazily.

    Apple Podcasts
    1
    Torps3993
    United States8 months ago
  • The Best Podcast Ever

    Incredible Podcast – A Must-Listen!

    David brings the perfect mix of insight, authenticity, and entertainment. Every episode feels like a conversation with a close friend who just gets it. Whether he’s dropping wisdom, sharing real stories, or interviewing amazing guests, there’s always something valuable to take away. Keep up the amazing work, David—this show is truly next level!

    Apple Podcasts
    5
    mattywblue
    United Statesa year ago
  • Thanks 🙏🏻

    Thank you for the excellent and informative podcast 🙏🏻

    Apple Podcasts
    5
    DAV.ROW
    South Africaa year ago
  • OCD and psilocybin

    Hi Dr Dave. Psychotherapist and psilocybin researcher here. OCD & other anxiety disorders tend to need much higher doses to make deep neurological changes that you addressed in this episode. Microdosing does not have the sufficient research as higher doses do. In the literature, psilocybin needs to be in the 20-50 mg range to make deep changes in neuroplasticity. This probably translates to somewhere in the range of 3-5 grams of dried fruit (depends on strength of strain). It’s not ... more

    Apple Podcasts
    5
    Jnewmark44
    United States2 years ago
  • Change

    Thank you Nakama.

    Your Hawaii broadcast made me think a lot…I’m going to listen to this broadcast again and give it a lot of thought.

    It really touched home for me.

    As I looked at the clock, the microwave said 515 so I looked up the number.

    As the meaning of angel number 515 is linked to personal freedom, major life changes, and the fact that you have the power to create your own reality, these can be the beautiful energies circling this triptych of digits.

    Thank you, Dave. I look forward to... more

    Apple Podcasts
    5
    Bewegirl
    United States2 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Some critiques note heavy Patreon promotion and perceived monetization pressures.
Listeners praise authentic, compassionate hosting and community focus, with many appreciating practical coaching and safety emphasis.
Episodes routinely earn praise for balancing personal stories with actionable microdosing guidance.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

How to Feel Calmer
Q: What do you mean that the source of pain is also the source of healing?
Pain signals imbalance and, rather than suppressing it, you should explore what it's signaling, because that exploration can guide you toward healing and growth.
Mark’s Magic Mushroom – Moved to the Philippines to Start Over | 2026 Ep11
Q: What prompted you to move to the Philippines at 63?
A combination of worsening health, caregiving responsibilities at home, and a deep longing for happiness and a life that felt possible beyond the constraints of the U.S. environment. The Philippines offered warmth, community, and a sense of renewal that aligned with his desire to live more fully.
Women’s Health – How Do You Know if Your Microdosing is Working?
Q: What are some signs that microdosing is genuinely helping a woman's mental and emotional health versus that something needs to be adjusted or even paused?
Microdosing is helping if the issues you started taking it for show improvement, such as reduced sensitivity, brain fog, or hormonal symptoms.
Women’s Health – How to Feel Better NOW!
Q: How does emotional labor show up in women and how can microdosing support them?
Emotional labor manifests as carrying invisible responsibilities and expectations, and microdosing can help mitigate these pressures by focusing on growth rather than fixing what's perceived as broken.
Women’s Health – How to Feel Better NOW!
Q: How do women's bodies and nervous systems respond differently to microdosing compared to men?
Women's responses are influenced by their hormones, stress, and unique emotional loads, with significant physiological changes during menstrual cycles, perimenopause, and menopause.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
Professions
Age Range
Household Income
Social Media Reach

Frequently Asked Questions About Microdose U

What is Microdose U about and what kind of topics does it cover?

The show centers on psilocybin microdosing as a tool for depression, anxiety, PTSD, and overall mental health, blending personal journey with practical coaching, community support, and expert-tinged discussions. Across episodes, hosts explore set, setting, dosing, harm reduction, and behavioral changes, often weaving in listener questions, Patreon community insights, and real-world testimonials. A standout pattern is the emphasis on steady, holistic growth through coaching, accountability, and community, rather than quick fixes, with a strong focus on safety, integration, and responsible use. The format frequently features guest inputs or takeover segments, reinforcing a lived-experience angle and a supportive, membership-driven learning en... more

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Which podcasts are similar to Microdose U?

These podcasts share a similar audience with Microdose U:

1. The Psychedelic Podcast
2. Microdose U - Psilocybin Microdosing for Depression and Anxiety
3. Finding Freedom with Peter Crone
4. The Rich Roll Podcast
5. Lifespan with Dr. David Sinclair

How many episodes of Microdose U are there?

Microdose U launched 5 years ago and published 488 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact Microdose U?

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Where can I see ratings and reviews for Microdose U?

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What guests have appeared on Microdose U?

Recent guests on Microdose U include:

1. River D. Knight
2. River Denyte
3. River Knight
4. Mark Jackson
5. Ryan Estes
6. Jordan Power
7. Nico Dosenbach
8. Dr. Uchi Odiatu

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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