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Artwork for RealTalk MS

RealTalk MS

Jon Strum
Multiple Sclerosis
National MS Society
Clinical Trials
Exercise
Mental Health
Neurology
Women's Health
Artificial Intelligence
Mcdonald Criteria
Menopause
Progressive MS
Precision Medicine
Neuroprotection
Caregiving
Covid-19
Tolebrutinib
Sanofi
Healthcare Advocacy
Myelin Repair
Neuroimmunology

Jon Strum cuts through all the jargon and breaks down the latest multiple sclerosis news. You'll meet the scientists who are creating tomorrow's MS treatments today. You'll hear from the experts discussing how the latest tweaks and changes to our healthcare laws will impact your MS treatment. And we'll be talking to the courageous MS warriors who are out there advocating on behalf of the MS commun... more

PublishesWeeklyEpisodes507Founded9 years ago
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Artwork for RealTalk MS

Latest Episodes

For decades, an MS diagnosis came with outdated advice and significant uncertainty regarding starting a family. Today, the conversation has shifted from "Is it possible?" to "How do we optimize the journey?" This week, we're taking a deep dive into t... more

Myelin repair is a natural function. But, for people living with MS, that ability to repair myelin eventually stops working. New research led by my guest, Dr. Larry Sherman, may explain why that happens and point to new possibilities for future myeli... more

The annual meeting of the American Academy of Neurology is underway in Chicago this week, and one of the highlights is the presentation of the John Dystel Prize for Research in Multiple Sclerosis, awarded jointly by the National MS Society and the Am... more

An exercise program can be hard to start and even more difficult to stick with. But the evidence-based benefits speak for themselves. For people living with MS, it can mean improving quality of life without having to rely on a pill, injection, or inf... more

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Recent Guests

Larry Sherman
Professor at Oregon National Primate Research Center, Oregon Health & Science University
OHSU Oregon National Primate Research Center
Episode: Episode 452: Why Natural Myelin Repair Stops Working for People with MS (And How It Could Be Re-Started!) with Dr. Larry Sherman
Ludwig Kappos
Physician-scientist and director of the Research Center for Clinical Neuroimmunology and Neuroscience Basel
University Hospital Basel, Switzerland
Episode: Episode 451: Meet the 2026 Winner of the John Dystel Prize for MS Research with Dr. Ludwig Kappos
Robert Motl
Director of the Exercise Neuroscience Research Laboratory, University of Illinois Chicago
University of Illinois at Chicago
Episode: Episode 450: Exercise is Medicine for People with MS with Dr. Robert Motl
Sara Loud
CEO of the Accelerated Cure Project and iConquer MS leader
Accelerated Cure Project / iConquer MS
Episode: Episode 449: Putting People Affected by MS at the Center of MS Research with Sara Loud, Stephanie Buxhoeveden, and Hollie Schmidt
Stephanie Buxhoeveden
Chief Science Officer, researcher, nurse practitioner, and person living with MS
iConquer MS
Episode: Episode 449: Putting People Affected by MS at the Center of MS Research with Sara Loud, Stephanie Buxhoeveden, and Hollie Schmidt
Hollie Schmidt
Vice President of Scientific Operations, leader of Real MS Longitudinal Study and Prada Initiative
iConquer MS
Episode: Episode 449: Putting People Affected by MS at the Center of MS Research with Sara Loud, Stephanie Buxhoeveden, and Hollie Schmidt
David Silbaugh
MS activist and retired US Army colonel
United States Army (retired) and MS advocacy community
Episode: Episode 448: At the National MS Society's Public Policy Conference with David, Cliff, and Michelle
Cliff Currie
MS activist from North Carolina
MS advocacy community
Episode: Episode 448: At the National MS Society's Public Policy Conference with David, Cliff, and Michelle
Brigitte Delaney
Captain of the Many Sisters WALK team
Many Sisters WALK MS
Episode: Episode 447: Walking with Many Sisters Toward a Cure with Brigitte Delaney

Host

Jon Strum
Host of RealTalk MS

Reviews

4.7 out of 5 stars from 220 ratings
  • Because Science

    This podcast makes MS research approachable without losing the depth that actually matters.

    I value how the host, Jon Strum, walks through the latest research and explains not just the WHAT, but WHY it matters—what it could mean for treatment, progression, and everyday life with MS. Jon helps turn complex studies into something you can understand and think about.

    Listening to this podcast makes me more informed. It’s become a go-to for staying up-to-date on MS research in a way that is clear, th... more

    Apple Podcasts
    5
    Zia Nova
    United Statesa month ago
  • Amazing and informative! I love how things are broken down for easy understanding.

    Podcast Addict
    5
    PodcastListenerL
    2 months ago
  • Use your voice

    Excellent podcast 10/28/25. US Const protects MS pts. Current admin disallows DOJ to prosecute. In this situation, ride your State & US Reps hard. Speak out loud about this. Strongly consider not only suing co but also Board Members of co personally. That’s where you will see change. Too often folks are unaware that Board Members jobs are demanded legally. Therefore, if they fail to esp deliberately to do their duties, they are in violation of most often reg law. Seek out an admin or reg attorne... more

    Apple Podcasts
    5
    Written Art
    United States6 months ago
  • Helpful and inspiring

    Wow- I can’t believe I just found out about this podcast! It is so informative and keeps me educated on so many things. The resources provided are super!

    Apple Podcasts
    5
    Bubblesforver123
    United States2 years ago
  • Episode after episode I come away feeling far better informed and empowered. Jon is gifted at breaking down the science in ways we can all understand. He also works very hard to deliver on topics that are close to many of our hearts in really important ways. Also his work before and during the podcast is only outdone by the "Session Notes" and the "Bonus Content" that make it so easy to access information, materials, research, etc. We are thrilled that he is so committed and so impactful.

    Podchaser
    5
    John Bradley
    3 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Many reviews emphasize the show's usefulness as a reliable MS information source and appreciate the range of topics from clinical trials to caregiver perspectives.
Some listeners note strong callouts for accessibility and actionable insights, while a few mention a desire for broader guest diversity or more patient-centric storytelling.
Audience resonates with the mix of cutting-edge research and lived experience, and often mentions the host's ability to surface policy and advocacy angles.
Overall, listeners describe the host as knowledgeable and the guests as top-tier experts, with clear, accessible discussion that translates complex science for a broad audience.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Episode 452: Why Natural Myelin Repair Stops Working for People with MS (And How It Could Be Re-Started!) with Dr. Larry Sherman
Q: I hope you'll start us off by explaining what myelin is and the role it plays in MS.
Myelin wraps around nerve cells to protect them and speeds up signal transmission; its loss in MS disrupts motor, sensory, and cognitive functions, creating widespread symptoms.
Episode 451: Meet the 2026 Winner of the John Dystel Prize for MS Research with Dr. Ludwig Kappos
Q: What do you see as the biggest remaining hurdle for progressive MS and how should we test new therapies to address it?
We need new paradigms and endpoints beyond inflammatory activity; digital measures and multi-modal assessments, including biology-informed approaches, are crucial to identify therapies that show true progression impact.
Episode 451: Meet the 2026 Winner of the John Dystel Prize for MS Research with Dr. Ludwig Kappos
Q: Looking back, what has been the most direct impact of your contributions on the day-to-day lives of people with MS?
My involvement in the design of leading clinical trials over decades and advancing methodologies has led to the approval of nearly all available disease-modifying drugs, improving prognosis and life expectancy for people with MS.
Episode 451: Meet the 2026 Winner of the John Dystel Prize for MS Research with Dr. Ludwig Kappos
Q: You've been involved in MS research for decades. What is the core message you want the global MS community to take home this year?
The core message is that we have reached a very satisfactory understanding and treatment state, but we must learn from failures to stop progression and halting progression requires improving the states and symptoms, with methods that are similar yet adapted to address progression.
Episode 450: Exercise is Medicine for People with MS with Dr. Robert Motl
Q: What role can a physical therapist play in building an exercise program for MS?
Neurological physical therapists can evaluate and diagnose underlying musculoskeletal or neural activation issues, address them, and design an individualized exercise program that fits a patient's abilities and goals, including adaptations for balance, strength, and aerobic conditioning.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About RealTalk MS

What is RealTalk MS about and what kind of topics does it cover?

This show centers on MS research, treatment advances, and real-world implications for people living with multiple sclerosis. Episodes frequently feature top neurologists and researchers discussing new trial results, diagnostic innovations, and emerging therapies, often paired with patient advocates or individuals living with MS who share lived experiences. The tone balances scientific rigor with practical, policy, and everyday-life considerations, making it useful for patients, caregivers, clinicians, advocates, and industry professionals seeking the latest developments and their real-world impact. A standout is the consistent pairing of cutting-edge research with patient perspectives, plus attention to regulatory and healthcare access issu... more

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How many listeners does RealTalk MS get?

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What are the audience demographics for RealTalk MS?

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How many subscribers and views does RealTalk MS have?

To see how many followers or subscribers RealTalk MS has on Spotify and other platforms such as Castbox and Podcast Addict, simply upgrade your account. You'll also find viewership figures for their YouTube channel if they have one.

Which podcasts are similar to RealTalk MS?

These podcasts share a similar audience with RealTalk MS:

1. MeSsy with Christina Applegate & Jamie Lynn Sigler
2. The MSing Link
3. Living Well with Multiple Sclerosis
4. That Can't Be True with Chelsea Clinton
5. 10% Happier with Dan Harris

How many episodes of RealTalk MS are there?

RealTalk MS launched 9 years ago and published 507 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact RealTalk MS?

Our systems regularly scour the web to find email addresses and social media links for this podcast. We scanned the web and collated all of the contact information that we could find in our podcast database. But in the unlikely event that you can't find what you're looking for, our concierge service lets you request our research team to source better contacts for you.

Where can I see ratings and reviews for RealTalk MS?

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What guests have appeared on RealTalk MS?

Recent guests on RealTalk MS include:

1. Larry Sherman
2. Ludwig Kappos
3. Robert Motl
4. Sara Loud
5. Stephanie Buxhoeveden
6. Hollie Schmidt
7. David Silbaugh
8. Cliff Currie

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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