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RealTalk MS

Jon Strum
Multiple Sclerosis
National MS Society
Clinical Trials
Exercise
Mental Health
Mcdonald Criteria
Neurology
Women's Health
Artificial Intelligence
Menopause
Caregiving
Progressive MS
Precision Medicine
Neuroprotection
Covid-19
Tolebrutinib
Sanofi
Healthcare Advocacy
Myelin Repair
Neuroimmunology

Jon Strum cuts through all the jargon and breaks down the latest multiple sclerosis news. You'll meet the scientists who are creating tomorrow's MS treatments today. You'll hear from the experts discussing how the latest tweaks and changes to our healthcare laws will impact your MS treatment. And we'll be talking to the courageous MS warriors who are out there advocating on behalf of the MS commun... more

PublishesWeeklyEpisodes534Founded9 years ago
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Artwork for RealTalk MS

Latest Episodes

Our coverage of MSToronto 2026 continues this week with two important conversations. First, we'll hear from Dr. Jeffrey Cohen about the latest clinical findings on CAR-T cell therapy as a potential treatment for MS. Then, Dr. Robert Fox will update u... more

Last week, about 8,000 MS researchers and clinicians arrived in Toronto, Canada, for MSToronto 2026, the joint meeting of the Americas Committee for Treatment and Research in MS and the European Committee for Treatment and Research in MS, and the lar... more

Welcome to a special episode of RealTalk MS and The ECTRIMS Podcast! MS Toronto 2026 concluded with the event we were most looking forward to -- Patient Community Day -- where some of the top MS experts in the world broke down the research presented ... more

Jan Janisch-Hanzlik was the first MS patient to receive CAR T-cell therapy as part of a clinical trial. We met Jan last year, in episode 424 of RealTalk MS, when she gave us a first-hand report on how she was responding to this treatment.

This wee... more

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Recent Guests

Jeffrey Cohen
Neurologist and director of the Experimental Therapeutics Program at the Cleveland Clinic's Mellen Center
Cleveland Clinic
Episode: Episode 480: MSToronto 2026 with Dr. Jeffrey Cohen and Dr. Robert Fox
Robert Fox
Neurologist, MS clinical-trial investigator, and chair of the International Progressive MS Alliance Scientific Steering Committee
Cleveland Clinic
Episode: Episode 480: MSToronto 2026 with Dr. Jeffrey Cohen and Dr. Robert Fox
Bruce Bebo
Chief Research and Medical Affairs Officer at the National MS Society
National MS Society
Episode: Episode 479: From MSToronto 2026 with Dr. Bruce Bebo and Kristine Werner Ozug
Kristine Werner Ozug
RealTalk MS producer who shares her perspective as a person living with MS
RealTalk MS
Episode: Episode 479: From MSToronto 2026 with Dr. Bruce Bebo and Kristine Werner Ozug
Peter Feys
MS rehabilitation expert and professor at Hasselt University.
Hasselt University
Episode: Episode 478: From MSToronto 2026 Patient Community Day with Professor Peter Feys and Karen Jacoby
Karen Jacoby
Person living with MS and MSCanada Ambassador.
MSCanada
Episode: Episode 478: From MSToronto 2026 Patient Community Day with Professor Peter Feys and Karen Jacoby
Jan Janisch-Hanzlik
First person with MS to receive allogeneic CAR T-cell therapy in a clinical trial.
Episode: Episode 477: One Year After CAR T-Cell Therapy with Jan Janisch-Hanzlik
Dana Foote
National Managing Partner for Audit & Assurance Operations at KPMG US and MS community leader.
KPMG US
Episode: Episode 476: MS in the Workplace with Dana Foote
Dr. Elizabeth Gromisch
Mandel Center for Comprehensive MS Care and Neuroscience Research, Mount Sinai Rehabilitation Hospital
Episode: Episode 475: New Tools and Strategies for Managing MS-Related Cognitive Changes with Dr. Elizabeth Gromisch

Host

Jon Strum
Host of RealTalk MS; engages with clinicians, researchers, and advocates to simplify MS science and care implications.

Reviews

4.7 out of 5 stars from 224 ratings
  • Because Science

    This podcast makes MS research approachable without losing the depth that actually matters.

    I value how the host, Jon Strum, walks through the latest research and explains not just the WHAT, but WHY it matters—what it could mean for treatment, progression, and everyday life with MS. Jon helps turn complex studies into something you can understand and think about.

    Listening to this podcast makes me more informed. It’s become a go-to for staying up-to-date on MS research in a way that is clear, th... more

    Apple Podcasts
    5
    Zia Nova
    United States7 months ago
  • Amazing and informative! I love how things are broken down for easy understanding.

    Podcast Addict
    5
    PodcastListenerL
    8 months ago
  • Use your voice

    Excellent podcast 10/28/25. US Const protects MS pts. Current admin disallows DOJ to prosecute. In this situation, ride your State & US Reps hard. Speak out loud about this. Strongly consider not only suing co but also Board Members of co personally. That’s where you will see change. Too often folks are unaware that Board Members jobs are demanded legally. Therefore, if they fail to esp deliberately to do their duties, they are in violation of most often reg law. Seek out an admin or reg attorne... more

    Apple Podcasts
    5
    Written Art
    United Statesa year ago
  • Helpful and inspiring

    Wow- I can’t believe I just found out about this podcast! It is so informative and keeps me educated on so many things. The resources provided are super!

    Apple Podcasts
    5
    Bubblesforver123
    United States2 years ago
  • Episode after episode I come away feeling far better informed and empowered. Jon is gifted at breaking down the science in ways we can all understand. He also works very hard to deliver on topics that are close to many of our hearts in really important ways. Also his work before and during the podcast is only outdone by the "Session Notes" and the "Bonus Content" that make it so easy to access information, materials, research, etc. We are thrilled that he is so committed and so impactful.

    Podchaser
    5
    John Bradley
    4 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

The host's interviews are consistently informative and respectful of diverse MS perspectives.
Some listeners note the show's emphasis on policy and advocacy is particularly valuable for stakeholders.
Fans highlight practical, research-backed guidance for daily living with MS.
Listeners praise accessible explanations of MS research and care.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Episode 479: From MSToronto 2026 with Dr. Bruce Bebo and Kristine Werner Ozug
Q: What do I need to do in the meantime when science needs to reach consensus on what we call MS?
Kristine Werner Ozug says she can focus on communicating with her healthcare team, sharing symptoms and goals, considering rehabilitation and mental-health support, and maintaining social connections while research and diagnostic frameworks develop.
Episode 479: From MSToronto 2026 with Dr. Bruce Bebo and Kristine Werner Ozug
Q: What are some of the things that really are top of mind for you as you leave the meeting?
Bruce Bebo highlights research moving beyond relapse control toward chronic inflammation, progression, earlier and more accurate diagnosis, and the possibility of preventing MS.
Episode 480: MSToronto 2026 with Dr. Jeffrey Cohen and Dr. Robert Fox
Q: So as you present this update here at MS Toronto 2026, where or how do you see this global collaborative model has moved the research needle the fastest?
Fox describes the Alliance's work in three areas: understanding progressive MS biology, making trials faster and more efficient, and addressing symptoms and everyday functioning. Its efforts include funded research, collaborative groups, and work with regulators on fluid biomarkers.
Episode 480: MSToronto 2026 with Dr. Jeffrey Cohen and Dr. Robert Fox
Q: I hope you'll start us off by briefly explaining what CAR-T cell therapy is and what's meant by an immune reset.
Cohen explains that CAR-T cells are engineered T lymphocytes designed to recognize specific targets, including B cells. Their depletion of B cells followed by repopulation may produce a more normal immune profile, which is the proposed immune reset.
Episode 478: From MSToronto 2026 Patient Community Day with Professor Peter Feys and Karen Jacoby
Q: Has rehab been shown to be effective for people living with progressive MS?
Feys says people with progressive MS can benefit from intensive upper-limb, gait, and balance practice. The gains may be limited and will not necessarily restore normal movement, but practice can make movement more automatic and less tiring.

Audience Metrics

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Frequently Asked Questions About RealTalk MS

What is RealTalk MS about and what kind of topics does it cover?

The show centers MS-focused conversations that distill complex research and clinical developments into practical, listener-friendly takeaways. Expect episodes that pair clinicians, researchers, and patient advocates to unpack how new therapies, lifestyle interventions, and policy changes affect real-world MS care, daily living, and decision-making. A notable strength is bridging scientific insights with actionable guidance—from shared decision-making with care teams to wearable tech, rehabilitation, and accessibility—often featuring long-running patient–provider partnerships and global perspectives. This mix makes it valuable for patients, caregivers, clinicians, and industry partners seeking up-to-date MS knowledge and practical implicatio... more

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How many episodes of RealTalk MS are there?

RealTalk MS launched 9 years ago and published 534 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on RealTalk MS?

Recent guests on RealTalk MS include:

1. Jeffrey Cohen
2. Robert Fox
3. Bruce Bebo
4. Kristine Werner Ozug
5. Peter Feys
6. Karen Jacoby
7. Jan Janisch-Hanzlik
8. Dana Foote

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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