
On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.
| Publishes | Weekly | Episodes | 90 | Founded | 2 years ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | Society & CulturePersonal JournalsHealth & Fitness | |||

This week, Christina and Jamie are revisiting their conversation with Deb Dana, LCSW, a clinician and speaker specializing in complex trauma. They discuss how to understand our nervous systems, polyvagal theory, how to feel safe in a body that may fe... more
This week, Christina and Jamie read listener emails and discuss big feelings, reality dating shows, guilt, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sp... more
This week, we revisit conversations with three incredible guests: Edie Falco, Jean Smart, and Katey Sagal.
Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by... more
This week, Christina and Jamie are joined by Robert Iler, who starred on "The Sopranos" with Jamie. They discuss memories from their time on the show, his path to becoming sober, his friendship with Jamie, and much more.
Executive Producers: Christi... more
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Hi Christina, I’m Shannon’s niece & got all of your hand me downs from Sadie to Scottie to Abby! I also loved your Hudson pregnancy jeans for that pregnancy years ago! I wanted to stop in and tell you I was recently diagnosed with MS in October and the only joy I have right now is your podcast. I’ve cried harder but also have felt like our hearts have been connected weirdly. I just wanted to say “hi” and thank you. You just keep giving me gifts without even knowing that’s what you are doing ❤️
Dad had and I have MS. I listened to the first episode but I’m a regular every day American with MS and found it didn’t relate well with those challenges. Loved “dead to me” and support to these ladies. In fairness I only listened to one episode—I guess I just didn’t want to listen to famous people complain about their access to medical care is my honest feedback so that episode didn’t do it for me. Maybe I ll try another one later. These actresses have the right to give themselves permission to... more
We are all human and these two beautiful humans remind us of that and they represent humanity in the most special way. I can’t wait to listen each week!
There are many podcasts out there supporting many different appetites for discuss.
However, this very special MeSsy podcast is one that is heartwarming, gutwrenching, emotion-generating, but most of all one that makes you feel supported and cared about. I personally do not have MS or any physical limitations at this time, however, life has ebb and flowed and presented a roller coaster of challenges for me and this podcast has helped me through every single issue while helping me still feel comfo... more
This podcast used to be the first one I listened to on Tuesday mornings. Now I don’t even listen every week. I loved both of these women as actors and on the show when it first started. Been listening since day one.
But now, Christina is wearing on me. I don’t have MS and I can’t relate to their struggles, only sympathize. I don’t blame Christina for being bitter, I would be too.
But every guest, every letter, Christina interrupts and makes it about herself. Every single time. Multiple times ... more
Key themes from listener reviews, highlighting what works and what could be improved about the show.
How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.
Apple Podcasts | #26 | |
Apple Podcasts | #18 | |
Apple Podcasts | #243 | |
Apple Podcasts | #60 | |
Apple Podcasts | #176 | |
Apple Podcasts | #35 |
Recent interactions between the hosts and their guests.
Listeners, social reach, demographics and more for this podcast.
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This podcast offers an authentic and heartfelt exploration of life's challenges, particularly focusing on the experiences of living with multiple sclerosis (MS). The hosts, who candidly discuss their personal struggles and triumphs, foster a sense of community through their shared vulnerabilities. Topics often revolve around relationships, parenting, and the emotional toll of chronic illness, ensuring listeners feel understood and supported. Unique in its blend of humor and sincerity, each episode invites guests from various backgrounds, making it relatable to anyone grappling with life's unexpected difficulties. The hosts aim to inspire resilience and promote open conversations about pain, mental health, and personal growth, encouraging li... more
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4. Literally! With Rob Lowe
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this podcast launched 2 years ago and published 90 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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Recent guests on this podcast include:
1. Rob Iler
2. Craig Thomas
3. Baylen Dupree
4. Megan Mullally
5. Cindy Locke
6. Fraser Olender
7. Dr. Daniel Amen
8. Ed Helms
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