MeSsy with Christina Applegate & Jamie Lynn Sigler
Wishbone ProductionOn this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.
| Publishes | Weekly | Episodes | 127 | Founded | 2 years ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | Personal JournalsHealth & FitnessSociety & Culture | |||
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Latest Episodes
This week, Jamie sits down with hospice nurse Julie McFadden to talk about changing the way we think about death, what she’s learned from those at the end of life, and how accepting our mortality can help us live more fully in the present.
Executive... more
This week, Jamie sits down with one of her best friends, Becca Tobin, for a conversation about infertility, pregnancy loss, surrogacy, and finding hope after years of uncertainty. They explore grief, resilience, the unexpected paths to parenthood, an... more
This week, Jamie sits down with Amanda Kloots for an honest conversation about finding joy alongside heartbreak. Amanda opens up about losing her husband, Nick Cordero, how her grief has evolved over the past six years, why she no longer believes we ... more
On this episode of Living With It, Jamie sits down with Kate Doerge to discuss finding hope after profound loss, recognizing signs from loved ones, and the five actions that can transform the way we move through grief.
Novartis in neuroscience
o Ou... more
Key Facts
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Reviews
- Awesome! Love the unfiltered Real Kiki and Jamie
Thank you for being so true, transparent, real, unfiltered. I’m learning so much. We all have life stuff.
Apple Podcasts5Aura curious
United States18 days ago - I have had it for 11 years
I have always loved Christina applegate while growing up but to know someone I wanted to be like has the same thing I do. Well it throws me for a loop. She’s right it freaking sucks! At 41 I shouldn’t be doing half the stuff I have to do until I’m 90! I feel like I lost alot and I lost a lot of friends.its not an easy disease to deal with. I envy all of you and I hope one day I can tell my story. 🧡
Apple Podcasts5SukimaeUnited Statesa month ago - This is everything to me!
I can’t believe how long it took me to find this podcast. I’m so happy I did! I also am only on the 20th episode, so I’m so happy I have so many more. I just finished both books. They were incredibly inspirational and eye opening. I can relate to both of you and I wish I could be best friends with you both! I have very similar symptoms, especially with my legs. I can relate to staying in bed. It’s my safe place. I am surrounded by amazing family and friends, but have felt so alone in my diagnosi... more
Apple Podcasts5Jillali18United Statesa month ago - Loved both your books
Everyone should buy your books, so good
Apple Podcasts5Beans13!$rrUnited States2 months ago - Question for Christina
Excellent
Apple Podcasts4Flying Burrito Brothers!United States2 months ago
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Chart Rankings
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Apple Podcasts | #25 | United States/Society & Culture/Personal Journals |
Apple Podcasts | #20 |  Canada/Society & Culture/Personal Journals |
Apple Podcasts | #167 |  United Kingdom/Society & Culture/Personal Journals |
Apple Podcasts | #249 | Canada/Society & Culture |
Apple Podcasts | #58 |  Australia/Society & Culture/Personal Journals |
Apple Podcasts | #120 |  Italy/Society & Culture/Personal Journals |
Talking Points
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Frequently Asked Questions About This Podcast
What is This Podcast about and what kind of topics does it cover?
Two high-visibility hosts share vulnerable, candid conversations about navigating life with a chronic condition, balancing public attention with personal health journeys, and leaning on friendship and community for resilience. Episodes blend intimate storytelling, therapeutic conversations, and practical tips, often weaving sponsor reads into a conversational rhythm. Guests span actors, musicians, therapists, and creators who illuminate performance, wellness, trauma, caregiving, and advocacy, making the show a mix of raw honesty, humor, and actionable guidance for listeners facing illness or challenging life transitions. A standout is the consistent emphasis on real talk about MS, caregiving, and mental health, while spotlighting female fri... more
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Which podcasts are similar to this podcast?
These podcasts share a similar audience with this podcast:
1. Let's Talk Off Camera with Kelly Ripa
2. I Choose Me with Jennie Garth
3. Good Hang with Amy Poehler
4. Dear Chelsea
5. Armchair Expert with Dax Shepard
How many episodes of this podcast are there?
this podcast launched 2 years ago and published 127 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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What guests have appeared on this podcast?
Recent guests on this podcast include:
1. Becca Tobin
2. Amanda Kloots
3. Kate Doerge
4. Myriam Sandler
5. Amy Kurtz
6. Tamsen Fadal
7. Erin Moriarty
8. Mia Calabrese
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