Rephonic
Artwork for MeSsy with Christina Applegate & Jamie Lynn Sigler

MeSsy with Christina Applegate & Jamie Lynn Sigler

Wishbone Production
Multiple Sclerosis
Mental Health
Friendship
Chronic Illness
Therapy
Parenting Challenges
Emotional Support
Vulnerability
Health Struggles
Grief
Motherhood
Personal Struggles
Support Systems
Empathy
Chronic Illness Awareness
Body Image
Eating Disorders
Acting
Nurse Jackie
The Sopranos

On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

PublishesWeeklyEpisodes90Founded2 years ago
Number of ListenersCategories
Society & CulturePersonal JournalsHealth & Fitness

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Artwork for MeSsy with Christina Applegate & Jamie Lynn Sigler

Latest Episodes

This week, Christina and Jamie are revisiting their conversation with Deb Dana, LCSW, a clinician and speaker specializing in complex trauma. They discuss how to understand our nervous systems, polyvagal theory, how to feel safe in a body that may fe... more

This week, Christina and Jamie read listener emails and discuss big feelings, reality dating shows, guilt, and more.

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

Audio Engineer: Josh Windisch

This episode is sp... more

YouTube

This week, we revisit conversations with three incredible guests: Edie Falco, Jean Smart, and Katey Sagal.

Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick

Audio Engineer: Josh Windisch

This episode is sponsored by... more

YouTube

This week, Christina and Jamie are joined by Robert Iler, who starred on "The Sopranos" with Jamie. They discuss memories from their time on the show, his path to becoming sober, his friendship with Jamie, and much more.

Executive Producers: Christi... more

YouTube

Key Facts

Accepts Guests
Accepts Sponsors
Contact Information
Podcast Host
Number of Listeners
Find out how many people listen to this podcast per episode and each month.

Similar Podcasts

Recent Guests

Rob Iler
Actor known for his role in The Sopranos
Episode: Robert Iler
Craig Thomas
Emmy-nominated producer and writer, creator of How I Met Your Mother
Episode: How Vulnerable Can I Be? with Craig Thomas
Baylen Dupree
A young woman living with Tourette syndrome, known for her openness and advocacy.
Beautifully Complex
Episode: It’s Okay to Be Yourself with Baylen Dupree
Megan Mullally
Actor and singer, best known for her role as Karen Walker on Will & Grace.
Episode: Megan Mullally
Cindy Locke
A fellow MS warrior and friend of Christina who shares her personal experiences with MS.
Episode: Do What You Can When You Can
Fraser Olender
Star of Below Deck and Chief Stew
Below Deck
Episode: Fraser Olender
Dr. Daniel Amen
Popular psychiatrist, CEO of Amen Clinics, author, and researcher.
Amen Clinics
Episode: Change Your Brain, Change Your Pain with Dr. Daniel Amen
Ed Helms
Actor and comedian known for roles in The Office and The Hangover
Episode: Ed Helms
Dr. Gretchen Hawley
Physical therapist and MS certified specialist
Episode: Any Movement Counts with Doctor Gretchen

Hosts

Christina Applegate
Co-host of a personal and heartfelt podcast discussing health and life experiences, particularly focusing on multiple sclerosis (MS).
Jamie Lynn Sigler
Co-host and one of the key voices in discussing real-life challenges, including living with MS and other personal experiences.

Reviews

4.9 out of 5 stars from 5.7k ratings
  • My daughter wore Sadie’s hand me downs!

    Hi Christina, I’m Shannon’s niece & got all of your hand me downs from Sadie to Scottie to Abby! I also loved your Hudson pregnancy jeans for that pregnancy years ago! I wanted to stop in and tell you I was recently diagnosed with MS in October and the only joy I have right now is your podcast. I’ve cried harder but also have felt like our hearts have been connected weirdly. I just wanted to say “hi” and thank you. You just keep giving me gifts without even knowing that’s what you are doing ❤️

    Apple Podcasts
    5
    Katylouwho985
    United States4 days ago
  • Fellow MSer couldn’t relate

    Dad had and I have MS. I listened to the first episode but I’m a regular every day American with MS and found it didn’t relate well with those challenges. Loved “dead to me” and support to these ladies. In fairness I only listened to one episode—I guess I just didn’t want to listen to famous people complain about their access to medical care is my honest feedback so that episode didn’t do it for me. Maybe I ll try another one later. These actresses have the right to give themselves permission to... more

    Apple Podcasts
    2
    August Rivers Humanities
    United States14 days ago
  • Just wow!

    We are all human and these two beautiful humans remind us of that and they represent humanity in the most special way. I can’t wait to listen each week!

    Apple Podcasts
    5
    FriskybartlAtlanta
    United States14 days ago
  • Luv this podcast, LUV THEM BOTH!

    There are many podcasts out there supporting many different appetites for discuss.

    However, this very special MeSsy podcast is one that is heartwarming, gutwrenching, emotion-generating, but most of all one that makes you feel supported and cared about. I personally do not have MS or any physical limitations at this time, however, life has ebb and flowed and presented a roller coaster of challenges for me and this podcast has helped me through every single issue while helping me still feel comfo... more

    Apple Podcasts
    5
    SFFogwalker
    United Statesa month ago
  • More Jamie

    This podcast used to be the first one I listened to on Tuesday mornings. Now I don’t even listen every week. I loved both of these women as actors and on the show when it first started. Been listening since day one.

    But now, Christina is wearing on me. I don’t have MS and I can’t relate to their struggles, only sympathize. I don’t blame Christina for being bitter, I would be too.

    But every guest, every letter, Christina interrupts and makes it about herself. Every single time. Multiple times ... more

    Apple Podcasts
    4
    Metsfan0606
    United Statesa month ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Listeners commend the raw honesty that the hosts exhibit, particularly regarding their health struggles, which helps destigmatize mental and physical health challenges.
Many find the dynamic between Christina and Jamie Lynn to feel like a conversation between close friends, which resonates deeply with their audience.
The hosts create a genuinely supportive and humorous environment, making listeners feel connected and understood. People appreciate the relatable discussions surrounding chronic illness and parenting.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

How Vulnerable Can I Be? with Craig Thomas
Q: What was it like navigating the challenges you faced as a parent?
Craig shares insights into the emotional rollercoaster of raising a child with Jacobson Syndrome, emphasizing the importance of community and advocacy in overcoming challenges.
It’s Okay to Be Yourself with Baylen Dupree
Q: What advice would you give to anyone that might be listening to this that has Tourette's or thinks they have Tourette's?
To not feel alone. We're so much more alike than we are different.
Fraser Olender
Q: What has been the hardest thing about being on television?
Fraser states that being on television has been the hardest and most doubted decision of his life, pushing him into maturity and forcing him to confront public perception.
Fraser Olender
Q: How did you end up on Below Deck?
Fraser explains that he was a model agent before entering yachting, and a casting director from Below Deck found him and convinced him to join the show.
Fraser Olender
Q: Who was little Fraser growing up in England?
Fraser describes himself as incredibly shy and scared and a bit lost, often struggling with his identity and sexuality.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
Professions
Age Range
Household Income
Social Media Reach

Frequently Asked Questions About This Podcast

What is This Podcast about and what kind of topics does it cover?

This podcast offers an authentic and heartfelt exploration of life's challenges, particularly focusing on the experiences of living with multiple sclerosis (MS). The hosts, who candidly discuss their personal struggles and triumphs, foster a sense of community through their shared vulnerabilities. Topics often revolve around relationships, parenting, and the emotional toll of chronic illness, ensuring listeners feel understood and supported. Unique in its blend of humor and sincerity, each episode invites guests from various backgrounds, making it relatable to anyone grappling with life's unexpected difficulties. The hosts aim to inspire resilience and promote open conversations about pain, mental health, and personal growth, encouraging li... more

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Which podcasts are similar to this podcast?

These podcasts share a similar audience with this podcast:

1. Let's Talk Off Camera with Kelly Ripa
2. Sibling Revelry with Kate Hudson and Oliver Hudson
3. Reclaiming with Monica Lewinsky
4. Literally! With Rob Lowe
5. Armchair Expert with Dax Shepard

How many episodes of this podcast are there?

this podcast launched 2 years ago and published 90 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on this podcast?

Recent guests on this podcast include:

1. Rob Iler
2. Craig Thomas
3. Baylen Dupree
4. Megan Mullally
5. Cindy Locke
6. Fraser Olender
7. Dr. Daniel Amen
8. Ed Helms

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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