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Artwork for MeSsy with Christina Applegate & Jamie Lynn Sigler

MeSsy with Christina Applegate & Jamie Lynn Sigler

Wishbone Production
Multiple Sclerosis
Mental Health
Friendship
Chronic Illness
Therapy
Parenting Challenges
Emotional Support
Vulnerability
Health Struggles
Motherhood
Grief
Personal Struggles
Support Systems
Empathy
Chronic Illness Awareness
Body Image
Eating Disorders
Acting
The Sopranos
Nurse Jackie

On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

PublishesWeeklyEpisodes83Founded2 years ago
Number of ListenersCategories
Personal JournalsHealth & FitnessSociety & Culture

Listen to this Podcast

Artwork for MeSsy with Christina Applegate & Jamie Lynn Sigler

Latest Episodes

This week Christina and Jamie are joined by Baylen Dupree. She opens up about having Tourette syndrome, the importance of being yourself, why it's crucial to remember that everyone is struggling, and more.

Executive Producers: Christina Applegate, J... more

YouTube

This week Christina and Jamie are joined by Megan Mullally. They discuss how her role as Karen on Will & Grace came to be, understanding family trauma, the comfort of TV, and more.

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and All... more

YouTube

This week Christina and Jamie are joined by Christina’s friend, Cindy Locke. They share how they first connected online and discuss the impact of trauma, advice to people who are newly diagnosed, the importance of support, and more.

Executive Produc... more

YouTube

This week, Christina and Jamie are joined by Fraser Olender from “Below Deck.” They discuss what his job as chief stew actually entails, his journey to find his true self, the escape of being busy, and much more.

Executive Producers: Christina Apple... more

YouTube

Key Facts

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Number of Listeners
Find out how many people listen to this podcast per episode and each month.

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Recent Guests

Baylen Dupree
A young woman living with Tourette syndrome, known for her openness and advocacy.
Beautifully Complex
Episode: It’s Okay to Be Yourself with Baylen Dupree
Megan Mullally
Actor and singer, best known for her role as Karen Walker on Will & Grace.
Episode: Megan Mullally
Cindy Locke
A fellow MS warrior and friend of Christina who shares her personal experiences with MS.
Episode: Do What You Can When You Can
Fraser Olender
Star of Below Deck and Chief Stew
Below Deck
Episode: Fraser Olender
Dr. Daniel Amen
Popular psychiatrist, CEO of Amen Clinics, author, and researcher.
Amen Clinics
Episode: Change Your Brain, Change Your Pain with Dr. Daniel Amen
Ed Helms
Actor and comedian known for roles in The Office and The Hangover
Episode: Ed Helms
Dr. Gretchen Hawley
Physical therapist and MS certified specialist
Episode: Any Movement Counts with Doctor Gretchen
Clea Shearer
Co-founder of The Home Edit and breast cancer survivor
The Home Edit
Episode: Clea Shearer
Judd Apatow
Renowned director, producer, and writer known for his work on comedies like This is 40 and Anchorman.
Episode: Judd Apatow

Hosts

Christina Applegate
Co-host of a personal and heartfelt podcast discussing health and life experiences, particularly focusing on multiple sclerosis (MS).
Jamie Lynn Sigler
Co-host and one of the key voices in discussing real-life challenges, including living with MS and other personal experiences.

Reviews

4.9 out of 5 stars from 5.7k ratings
  • Freaking love this Podcast!!

    This podcast has made such a huge difference in my life! I love the connection between Christina and Jamie and truly feel like they are speaking to me on every episode. I was diagnosed with RRMS in 2008 and am now on disability. I am a 42 year old Mother and Grandmother who is still trying to find my new normal with all of these life changes. I always feel a lot better after listening to your show even though sometimes I will cry while I am laughing. Both of you are so open and raw about how you... more

    Apple Podcasts
    5
    Jamie Lee☮️🧡
    United Statesa month ago
  • You are for real

    I just found this podcast as I am living with cronic pain, waiting to be diagnosed maybe with ms, I don’t know… however listen to you guys it’s like a relief because I don’t feel alone, even when the waiting to be diagnosed is overwhelming. Thank you for being you and for showing as you are, we need more of this as we are all humans and vulnerability is a super power. Life is messy, and sweet at the same time! Keep going!

    Apple Podcasts
    5
    Paola Canada
    Canadaa month ago
  • Thank you for being real!

    I started listening to this podcast because my spouse has MS. I wanted to hear the realness about this disease. He doesn’t like talking about it and I just want to help/try to understand in anyway that I can. I appreciate that you both are so sharing and open on a difficult topic. I think you are helping more people than you know.

    Apple Podcasts
    5
    Dsmith48
    United Statesa month ago
  • Thank you Messy

    I just wanted to reach out to let you know how much your podcast means to me. Although I don’t have MS, I live with Rheumatoid Arthritis and I’m often struck by how many of the challenges you talk about- fatigue, pain, brain fog, the unpredictability of symptoms-feel so familiar.

    Listening to Messy gives me something rare: the feeling that someone else understands.

    I was diagnosed very late in life, two years ago at the age of 71. I have a loving, supportive family and I’m a first time “ Glamm... more

    Apple Podcasts
    5
    Twinkle225
    United Statesa month ago
  • EI Improvement

    Thank you ladies for being so genuine inside and out. Your podcast is not only helping me accept things that I cannot control but to others as well. This podcast is perfect to help build a stronger connection to your emotional intelligence.

    Apple Podcasts
    5
    Twisted Dust
    United Statesa month ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Listeners commend the raw honesty that the hosts exhibit, particularly regarding their health struggles, which helps destigmatize mental and physical health challenges.
Many find the dynamic between Christina and Jamie Lynn to feel like a conversation between close friends, which resonates deeply with their audience.
The hosts create a genuinely supportive and humorous environment, making listeners feel connected and understood. People appreciate the relatable discussions surrounding chronic illness and parenting.

Chart Rankings

Talking Points

Recent interactions between the hosts and their guests.

It’s Okay to Be Yourself with Baylen Dupree
Q: What advice would you give to anyone that might be listening to this that has Tourette's or thinks they have Tourette's?
To not feel alone. We're so much more alike than we are different.
Fraser Olender
Q: What has been the hardest thing about being on television?
Fraser states that being on television has been the hardest and most doubted decision of his life, pushing him into maturity and forcing him to confront public perception.
Fraser Olender
Q: How did you end up on Below Deck?
Fraser explains that he was a model agent before entering yachting, and a casting director from Below Deck found him and convinced him to join the show.
Fraser Olender
Q: Who was little Fraser growing up in England?
Fraser describes himself as incredibly shy and scared and a bit lost, often struggling with his identity and sexuality.
Live From the Hospital
Q: What advice do you have for someone with MS who is pregnant?
Work with your neurologist to understand your limits and gauge your body. Pregnancy can even help alleviate some MS symptoms. It's important to be in sync with your body during this time.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
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Age Range
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Frequently Asked Questions About This Podcast

What is This Podcast about and what kind of topics does it cover?

This podcast offers an authentic and heartfelt exploration of life's challenges, particularly focusing on the experiences of living with multiple sclerosis (MS). The hosts, who candidly discuss their personal struggles and triumphs, foster a sense of community through their shared vulnerabilities. Topics often revolve around relationships, parenting, and the emotional toll of chronic illness, ensuring listeners feel understood and supported. Unique in its blend of humor and sincerity, each episode invites guests from various backgrounds, making it relatable to anyone grappling with life's unexpected difficulties. The hosts aim to inspire resilience and promote open conversations about pain, mental health, and personal growth, encouraging li... more

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Which podcasts are similar to this podcast?

These podcasts share a similar audience with this podcast:

1. Let's Talk Off Camera with Kelly Ripa
2. Literally! With Rob Lowe
3. Sibling Revelry with Kate Hudson and Oliver Hudson
4. Making Space with Hoda Kotb
5. I Choose Me with Jennie Garth

How many episodes of this podcast are there?

this podcast launched 2 years ago and published 83 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on this podcast?

Recent guests on this podcast include:

1. Baylen Dupree
2. Megan Mullally
3. Cindy Locke
4. Fraser Olender
5. Dr. Daniel Amen
6. Ed Helms
7. Dr. Gretchen Hawley
8. Clea Shearer

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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