Rephonic
Artwork for MeSsy with Christina Applegate & Jamie Lynn Sigler

MeSsy with Christina Applegate & Jamie Lynn Sigler

Wishbone Production
Multiple Sclerosis
Mental Health
Friendship
Chronic Illness
Therapy
Parenting Challenges
Emotional Support
Vulnerability
Health Struggles
Motherhood
Grief
Personal Struggles
Support Systems
Empathy
Chronic Illness Awareness
Body Image
Eating Disorders
Acting
Cancer
Nurse Jackie

On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

PublishesWeeklyEpisodes102Founded2 years ago
Number of ListenersCategories
Personal JournalsHealth & FitnessSociety & Culture

Listen to this Podcast

Artwork for MeSsy with Christina Applegate & Jamie Lynn Sigler

Latest Episodes

This week, Christina and Jamie are joined by their friend Kelly Ripa. They discuss Kelly's career and how it began at a toy fair, the processing she had to do while writing her own book, the challenges of playing yourself on television, and much more... more

YouTube

This week, Christina and Jamie read listener emails and discuss skincare products from childhood, crazy animal stories, not thinking too far into the future, and much more.

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bre... more

YouTube

This week, Christina and Jamie read listener emails and discuss the Married... with Children reunion, catch up on their TV shows, Jamie opens up about a recent experience, and more.

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Al... more

YouTube

This week, Christina and Jamie read listener emails and discuss MS fatigue, finding little moments of self care, how to better communicate with friends, and more.

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

Aud... more

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Key Facts

Accepts Guests
Accepts Sponsors
Contact Information
Podcast Host
Number of Listeners
Find out how many people listen to this podcast per episode and each month.

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Recent Guests

Kelly Ripa
Mogul and media superstar
Ripa Productions
Episode: Kelly Ripa
Bobbi Brown
World-renowned makeup artist, beauty industry trailblazer, and founder of Jones Road Beauty.
Jones Road Beauty
Episode: Bobbi Brown
Dr. Will Cole
Functional medicine expert and New York Times bestselling author
Episode: The Impact of Inflammation with Dr. Will Cole
Meg Josephson
Psychotherapist, licensed clinical social worker, and author
Self
Episode: Are You Mad At Me? with Meg Josephson
Rob Iler
Actor known for his role in The Sopranos
Episode: Robert Iler
Craig Thomas
Emmy-nominated producer and writer, creator of How I Met Your Mother
Episode: How Vulnerable Can I Be? with Craig Thomas
Baylen Dupree
A young woman living with Tourette syndrome, known for her openness and advocacy.
Beautifully Complex
Episode: It’s Okay to Be Yourself with Baylen Dupree
Megan Mullally
Actor and singer, best known for her role as Karen Walker on Will & Grace.
Episode: Megan Mullally
Cindy Locke
A fellow MS warrior and friend of Christina who shares her personal experiences with MS.
Episode: Do What You Can When You Can

Hosts

Christina Applegate
Co-host known for her open and honest approach to discussing life with multiple sclerosis, drawing on her own experiences and fostering connection.
Jamie Lynn Sigler
Co-host who shares her personal journey with multiple sclerosis, emphasizing community support and relatable life experiences.

Reviews

4.9 out of 5 stars from 5.8k ratings
  • Thank you!

    I am about a year behind and listening to episodes. So I don’t know what’s happening with you right now, but I’m so grateful you’ve been sharing your experience. My sister and I both have neurogenic POTS, which has led to a lifetime of dysautonomia, due to late diagnoses. Listening to share your experiences, has helped keep me stay sane. The compassion you show for one another is very special. I hope that we all can have friends who listen to us and except who we are. Thank you for reminding me ... more

    Apple Podcasts
    5
    midwestfirefly
    United States24 days ago
  • Please don’t ever stop

    I don’t have MS but I do live with chronic pain that affects my daily life and relationships. I look forward to each new episode for validation, inspiration, insight and a few laughs. Thank you so much for sharing your raw and honest feelings and stories. It helps so, so much. So much love and admiration to you both ❤️

    Apple Podcasts
    5
    Raerae334
    United Statesa month ago
  • Only podcast I listen to all the way through.

    MeSsy is the bestest of the restest

    podcast, who knew MS is the thing that can rival every chronic illness I ever heard of?I don’t have MS, only severe, reactive arthritis, which has some underlying cause nobody knows, but causes pain, mobility and movement limitations, anxiety, affects body weight, and it doesn’t cover a fraction of the symptoms Christina and Jamie Lynne deal with, and from a much younger age! I used to work with folks with MS, helping them get Attendant Care, and I wish I knew... more

    Apple Podcasts
    5
    Giminomom
    United Statesa month ago
  • Love Messy

    I love your show and how honest you both are!

    Apple Podcasts
    5
    Stay 5
    United Statesa month ago
  • Very real and relatable

    Love your podcast. I appreciate your honesty. I don’t have MS, but I have been “living” with chronic pain (etc) conditions for over 20 years. It has been overwhelming and exhausting.

    Apple Podcasts
    5
    laurie2302
    United Statesa month ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

The podcast is praised for its ability to handle heavy topics with warmth and humor, contributing to its overall positive reception.
Some feel a disconnect if they are not directly affected by MS, suggesting the content may not always be universally relatable.
Listeners appreciate the raw honesty and vulnerability displayed by the hosts, finding comfort in their shared stories of living with MS.
There's a strong sense of community and support among listeners, with many finding solace in the shared experiences and insights.
The blend of humor and serious discussion about chronic illness resonates deeply, providing an engaging listening experience.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

The Impact of Inflammation with Dr. Will Cole
Q: Would you advise to begin in one area or the other, start slow because there's a lot of pitfalls?
It's important to meet patients where they're at and start with a plan they can consistently follow, focusing on manageable changes.
The Impact of Inflammation with Dr. Will Cole
Q: Can you just actually talk about what inflammation is? What is happening in the body?
Dr. Cole discusses the necessity of inflammation for bodily functions but emphasizes the problems caused by chronic inflammation and the importance of identifying underlying causes.
How Vulnerable Can I Be? with Craig Thomas
Q: What was it like navigating the challenges you faced as a parent?
Craig shares insights into the emotional rollercoaster of raising a child with Jacobson Syndrome, emphasizing the importance of community and advocacy in overcoming challenges.
It’s Okay to Be Yourself with Baylen Dupree
Q: What advice would you give to anyone that might be listening to this that has Tourette's or thinks they have Tourette's?
To not feel alone. We're so much more alike than we are different.
Fraser Olender
Q: What has been the hardest thing about being on television?
Fraser states that being on television has been the hardest and most doubted decision of his life, pushing him into maturity and forcing him to confront public perception.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
Professions
Age Range
Household Income
Social Media Reach

Frequently Asked Questions About This Podcast

What is This Podcast about and what kind of topics does it cover?

This show focuses on the candid experiences of two hosts living with multiple sclerosis (MS), exploring not only their personal struggles but also the broader emotional landscape of living with chronic illness. Episodes frequently feature their humorous yet heartfelt conversations that touch on topics such as coping strategies, community support, parenting challenges, and the importance of vulnerability. The hosts also engage with a variety of guests, including celebrities and experts, to discuss health and wellness, creating a diverse tapestry of insights that resonate with listeners navigating their own life challenges. Unique in its blend of humor and raw honesty, the content often provides a sense of belonging and understanding for thos... more

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Which podcasts are similar to this podcast?

These podcasts share a similar audience with this podcast:

1. Let's Talk Off Camera with Kelly Ripa
2. Dear Chelsea
3. Literally! With Rob Lowe
4. Sibling Revelry with Kate Hudson and Oliver Hudson
5. Good Hang with Amy Poehler

How many episodes of this podcast are there?

this podcast launched 2 years ago and published 102 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on this podcast?

Recent guests on this podcast include:

1. Kelly Ripa
2. Bobbi Brown
3. Dr. Will Cole
4. Meg Josephson
5. Rob Iler
6. Craig Thomas
7. Baylen Dupree
8. Megan Mullally

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