MeSsy with Christina Applegate & Jamie Lynn Sigler
Wishbone ProductionOn this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.
| Publishes | Twice weekly | Episodes | 139 | Founded | 3 years ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | Personal JournalsHealth & FitnessSociety & Culture | |||
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Latest Episodes
This week, Jamie sits down with jiu-jitsu champion and former UFC fighter Alberto Crane to talk about how his MS diagnosis forced him to redefine what it means to be strong. Alberto opens up about learning to slow down, embrace rest, and why sometime... more
This week on Living With It, Jamie sits down with Heather Dubrow for an honest conversation about embracing life’s pivots, protecting your peace, and giving yourself permission to want more.
Novartis in neuroscience
o Our ambition is to create a t... more
This week on MeSsy, Jamie sits down with her longtime friend, actress, writer, and musician Lindsey Kraft. They talk about growing up together, navigating rejection and self-doubt, and Lindsey’s unexpected journey from acting to writing her own one-w... more
This week on Living With It, Jamie sits down with her friend, Ryan Weiss. They talk about letting go of control, sitting with difficult emotions, knowing when it’s time to do things differently, and learning to trust what’s on the other side when lif... more
Key Facts
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Recent Guests
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Reviews
- Pining for the good ole days
Some things evolve and change and grow in awesome ways. Some things zig when they shoulda zagged.
What the heck is happening with this podcast? Yikes! MeSsy has become a mess.
Apple Podcasts2car crash gameing
United States2 months ago - Myriam Sandler was a great guest!
I loved your conversation with Myriam Sandler of Mothercould! Thanks to you both!
Apple Podcasts5MisawachickUnited States2 months ago - Awesome! Love the unfiltered Real Kiki and Jamie
Thank you for being so true, transparent, real, unfiltered. I’m learning so much. We all have life stuff.
Apple Podcasts5Aura curiousUnited States2 months ago - I have had it for 11 years
I have always loved Christina applegate while growing up but to know someone I wanted to be like has the same thing I do. Well it throws me for a loop. She’s right it freaking sucks! At 41 I shouldn’t be doing half the stuff I have to do until I’m 90! I feel like I lost alot and I lost a lot of friends.its not an easy disease to deal with. I envy all of you and I hope one day I can tell my story. 🧡
Apple Podcasts5SukimaeUnited States2 months ago - This is everything to me!
I can’t believe how long it took me to find this podcast. I’m so happy I did! I also am only on the 20th episode, so I’m so happy I have so many more. I just finished both books. They were incredibly inspirational and eye opening. I can relate to both of you and I wish I could be best friends with you both! I have very similar symptoms, especially with my legs. I can relate to staying in bed. It’s my safe place. I am surrounded by amazing family and friends, but have felt so alone in my diagnosi... more
Apple Podcasts5Jillali18United States3 months ago
Listeners Say
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Chart Rankings
How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.
Apple Podcasts | #24 | United States/Society & Culture/Personal Journals |
Apple Podcasts | #33 |  Canada/Society & Culture/Personal Journals |
Apple Podcasts | #62 |  Australia/Society & Culture/Personal Journals |
Apple Podcasts | #165 |  Italy/Society & Culture/Personal Journals |
Apple Podcasts | #10 |  Argentina/Society & Culture/Personal Journals |
Apple Podcasts | #24 |  Austria/Society & Culture/Personal Journals |
Talking Points
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Frequently Asked Questions About This Podcast
What is This Podcast about and what kind of topics does it cover?
MeSsy with Christina Applegate & Jamie Lynn Sigler features candid, vulnerable conversations centered on living with chronic illness (notably MS), grief, resilience, parenting, and personal growth. The hosts share real-life experiences, invite friends and guests from health, wellness, and entertainment to discuss tough topics with humor, honesty, and practical takeaways. A standout angle is the seamless integration of personal storytelling with advocacy and community support, often interwoven with sponsor messages that reinforce actionable guidance for listeners navigating chronic conditions. Potential listeners can expect relatable, no-holds-barred dialogue, actionable coping strategies, and a sense of shared experience that makes difficul... more
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Which podcasts are similar to this podcast?
These podcasts share a similar audience with this podcast:
1. Let's Talk Off Camera with Kelly Ripa
2. Reclaiming with Monica Lewinsky
3. Literally! With Rob Lowe
4. Sibling Revelry with Kate Hudson and Oliver Hudson
5. SmartLess
How many episodes of this podcast are there?
this podcast launched 3 years ago and published 139 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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What guests have appeared on this podcast?
Recent guests on this podcast include:
1. Ryan Weiss
2. Cat Cohen
3. Kelsey Chittick
4. Annie Meyers-Shyer
5. Jim Curtis
6. Bob Roth
7. Julie McFadden
8. Becca Tobin
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