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Artwork for MeSsy with Christina Applegate & Jamie Lynn Sigler

MeSsy with Christina Applegate & Jamie Lynn Sigler

Wishbone Production
Multiple Sclerosis
Mental Health
Friendship
Chronic Illness
Therapy
Parenting Challenges
Emotional Support
Vulnerability
Health Struggles
Grief
Motherhood
Personal Struggles
Empathy
Support Systems
Chronic Illness Awareness
Body Image
Eating Disorders
Acting
Nurse Jackie
Cancer

On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

PublishesWeeklyEpisodes81Founded2 years ago
Number of ListenersCategories
Personal JournalsHealth & FitnessSociety & Culture

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Artwork for MeSsy with Christina Applegate & Jamie Lynn Sigler

Latest Episodes

This week Christina and Jamie are joined by Christina’s friend, Cindy Locke. They share how they first connected online and discuss the impact of trauma, advice to people who are newly diagnosed, the importance of support, and more.

Executive Produc... more

This week, Christina and Jamie are joined by Fraser Olender from “Below Deck.” They discuss what his job as chief stew actually entails, his journey to find his true self, the escape of being busy, and much more.

Executive Producers: Christina Apple... more

YouTube

This week, Christina and Jamie read listener emails and discuss conditional friends, not identifying as the things that happen to us, staying honest, and more.

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

Audio ... more

YouTube

This week, Christina and Jamie are joined by Dr. Daniel Amen, a physician, double board-certified psychiatrist, and award-winning researcher. They discuss why pain can also live in your brain, the doom loop and how to get out of it, the cost of repre... more

YouTube

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Recent Guests

Dr. Daniel Amen
Popular psychiatrist, CEO of Amen Clinics, author, and researcher.
Amen Clinics
Episode: Change Your Brain, Change Your Pain with Dr. Daniel Amen
Ed Helms
Actor and comedian known for roles in The Office and The Hangover
Episode: Ed Helms
Dr. Gretchen Hawley
Physical therapist and MS certified specialist
Episode: Any Movement Counts with Doctor Gretchen
Clea Shearer
Co-founder of The Home Edit and breast cancer survivor
The Home Edit
Episode: Clea Shearer
Judd Apatow
Renowned director, producer, and writer known for his work on comedies like This is 40 and Anchorman.
Episode: Judd Apatow
Kaitlyn Bristowe
Reality star and podcast host
Off the Vine
Episode: Kaitlyn Bristowe
David Faustino
Actor known for his role in Married with Children
Episode: David Faustino
Conan O'Brien
Comedian, writer, and talk show host known for his unique brand of humor
Conan O'Brien Needs a Friend
Episode: Conan O'Brien
JoAnna Garcia Swisher
Actress, known for her roles across television
Episode: JoAnna Garcia Swisher

Hosts

Christina Applegate
Co-host of a personal and heartfelt podcast discussing health and life experiences, particularly focusing on multiple sclerosis (MS).
Jamie Lynn Sigler
Co-host and one of the key voices in discussing real-life challenges, including living with MS and other personal experiences.

Reviews

4.9 out of 5 stars from 5.6k ratings
  • Freaking love this Podcast!!

    This podcast has made such a huge difference in my life! I love the connection between Christina and Jamie and truly feel like they are speaking to me on every episode. I was diagnosed with RRMS in 2008 and am now on disability. I am a 42 year old Mother and Grandmother who is still trying to find my new normal with all of these life changes. I always feel a lot better after listening to your show even though sometimes I will cry while I am laughing. Both of you are so open and raw about how you... more

    Apple Podcasts
    5
    Jamie Lee☮️🧡
    United States12 days ago
  • You are for real

    I just found this podcast as I am living with cronic pain, waiting to be diagnosed maybe with ms, I don’t know… however listen to you guys it’s like a relief because I don’t feel alone, even when the waiting to be diagnosed is overwhelming. Thank you for being you and for showing as you are, we need more of this as we are all humans and vulnerability is a super power. Life is messy, and sweet at the same time! Keep going!

    Apple Podcasts
    5
    Paola Canada
    Canada15 days ago
  • Thank you for being real!

    I started listening to this podcast because my spouse has MS. I wanted to hear the realness about this disease. He doesn’t like talking about it and I just want to help/try to understand in anyway that I can. I appreciate that you both are so sharing and open on a difficult topic. I think you are helping more people than you know.

    Apple Podcasts
    5
    Dsmith48
    United States18 days ago
  • Thank you Messy

    I just wanted to reach out to let you know how much your podcast means to me. Although I don’t have MS, I live with Rheumatoid Arthritis and I’m often struck by how many of the challenges you talk about- fatigue, pain, brain fog, the unpredictability of symptoms-feel so familiar.

    Listening to Messy gives me something rare: the feeling that someone else understands.

    I was diagnosed very late in life, two years ago at the age of 71. I have a loving, supportive family and I’m a first time “ Glamm... more

    Apple Podcasts
    5
    Twinkle225
    United States22 days ago
  • EI Improvement

    Thank you ladies for being so genuine inside and out. Your podcast is not only helping me accept things that I cannot control but to others as well. This podcast is perfect to help build a stronger connection to your emotional intelligence.

    Apple Podcasts
    5
    Twisted Dust
    United States23 days ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Listeners commend the raw honesty that the hosts exhibit, particularly regarding their health struggles, which helps destigmatize mental and physical health challenges.
Many find the dynamic between Christina and Jamie Lynn to feel like a conversation between close friends, which resonates deeply with their audience.
The hosts create a genuinely supportive and humorous environment, making listeners feel connected and understood. People appreciate the relatable discussions surrounding chronic illness and parenting.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Live From the Hospital
Q: What advice do you have for someone with MS who is pregnant?
Work with your neurologist to understand your limits and gauge your body. Pregnancy can even help alleviate some MS symptoms. It's important to be in sync with your body during this time.
There Are All Kinds of Heartbreak
Q: What type of heartbreak do you find hardest to deal with?
Loss of a person still living and relationships left with emotional open wounds.
Kaitlyn Bristowe
Q: Can you tell us a little bit about that? And like, was that your first brush with therapy at that time?
Yes. Oh my gosh. Yes. And I'm so that was the greatest gift I ever gave myself was therapy, even though it was the last thing I wanted to do.
Conan O'Brien
Q: How do you handle difficult situations in your career?
Conan shares insights on perspective and the importance of surrounding oneself with good people.
Conan O'Brien
Q: What is the balance between hope and acceptance in dealing with chronic illness?
Jamie and Christina discuss the need for hope amidst acceptance of their chronic illness.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
Professions
Age Range
Household Income
Social Media Reach

Frequently Asked Questions About This Podcast

What is This Podcast about and what kind of topics does it cover?

This podcast offers an authentic and heartfelt exploration of life's challenges, particularly focusing on the experiences of living with multiple sclerosis (MS). The hosts, who candidly discuss their personal struggles and triumphs, foster a sense of community through their shared vulnerabilities. Topics often revolve around relationships, parenting, and the emotional toll of chronic illness, ensuring listeners feel understood and supported. Unique in its blend of humor and sincerity, each episode invites guests from various backgrounds, making it relatable to anyone grappling with life's unexpected difficulties. The hosts aim to inspire resilience and promote open conversations about pain, mental health, and personal growth, encouraging li... more

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Which podcasts are similar to this podcast?

These podcasts share a similar audience with this podcast:

1. Let's Talk Off Camera with Kelly Ripa
2. Literally! With Rob Lowe
3. Sibling Revelry with Kate Hudson and Oliver Hudson
4. Reclaiming with Monica Lewinsky
5. SmartLess

How many episodes of this podcast are there?

this podcast launched 2 years ago and published 81 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on this podcast?

Recent guests on this podcast include:

1. Dr. Daniel Amen
2. Ed Helms
3. Dr. Gretchen Hawley
4. Clea Shearer
5. Judd Apatow
6. Kaitlyn Bristowe
7. David Faustino
8. Conan O'Brien

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