MeSsy with Christina Applegate & Jamie Lynn Sigler
Wishbone ProductionOn this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.
| Publishes | Twice weekly | Episodes | 133 | Founded | 2 years ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | Personal JournalsHealth & FitnessSociety & Culture | |||
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Latest Episodes
This week, Jamie is joined by her longtime friend Annie Meyers-Shyer, the creator behind This Oak House. They talk about Annie’s unexpected second act, finding a new passion and career at 45, and why it’s never too late to bet on yourself. Annie also... more
This week on Living With It, Jamie sits down with Jim Curtis, a transformational coach, author, and wellness leader. They discuss how to radically accept the life you have without giving up hope for the life you want, the stories we build around our ... more
This week, Jamie sits down with a very special guest: her 13-year-old son, Beau. They have an honest conversation about what it’s been like growing up with a mom who has MS, how Jamie’s strength has shaped him, and what he wants other kids and parent... more
This week on Living With It, Jamie sits down with her friend Odette Annable. They discuss parenting a neurodivergent child, trusting your instincts, advocating for your family, and learning to let go of the need to have all the answers.
Novartis in ... more
Key Facts
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Recent Guests
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Reviews
- Pining for the good ole days
Some things evolve and change and grow in awesome ways. Some things zig when they shoulda zagged.
What the heck is happening with this podcast? Yikes! MeSsy has become a mess.
Apple Podcasts2car crash gameing
United Statesa month ago - Myriam Sandler was a great guest!
I loved your conversation with Myriam Sandler of Mothercould! Thanks to you both!
Apple Podcasts5MisawachickUnited Statesa month ago - Awesome! Love the unfiltered Real Kiki and Jamie
Thank you for being so true, transparent, real, unfiltered. I’m learning so much. We all have life stuff.
Apple Podcasts5Aura curiousUnited Statesa month ago - I have had it for 11 years
I have always loved Christina applegate while growing up but to know someone I wanted to be like has the same thing I do. Well it throws me for a loop. She’s right it freaking sucks! At 41 I shouldn’t be doing half the stuff I have to do until I’m 90! I feel like I lost alot and I lost a lot of friends.its not an easy disease to deal with. I envy all of you and I hope one day I can tell my story. 🧡
Apple Podcasts5SukimaeUnited States2 months ago - This is everything to me!
I can’t believe how long it took me to find this podcast. I’m so happy I did! I also am only on the 20th episode, so I’m so happy I have so many more. I just finished both books. They were incredibly inspirational and eye opening. I can relate to both of you and I wish I could be best friends with you both! I have very similar symptoms, especially with my legs. I can relate to staying in bed. It’s my safe place. I am surrounded by amazing family and friends, but have felt so alone in my diagnosi... more
Apple Podcasts5Jillali18United States2 months ago
Listeners Say
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Chart Rankings
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Apple Podcasts | #18 | United States/Society & Culture/Personal Journals |
Apple Podcasts | #41 |  Canada/Society & Culture/Personal Journals |
Apple Podcasts | #215 |  United Kingdom/Society & Culture/Personal Journals |
Apple Podcasts | #69 |  Australia/Society & Culture/Personal Journals |
Apple Podcasts | #215 |  Italy/Society & Culture/Personal Journals |
Apple Podcasts | #40 |  Israel/Society & Culture/Personal Journals |
Talking Points
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Audience Metrics
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Frequently Asked Questions About This Podcast
What is This Podcast about and what kind of topics does it cover?
MeSsy with Christina Applegate & Jamie Lynn Sigler features candid, vulnerable conversations centered on living with chronic illness (notably MS), grief, resilience, parenting, and personal growth. The hosts share real-life experiences, invite friends and guests from health, wellness, and entertainment to discuss tough topics with humor, honesty, and practical takeaways. A standout angle is the seamless integration of personal storytelling with advocacy and community support, often interwoven with sponsor messages that reinforce actionable guidance for listeners navigating chronic conditions. Potential listeners can expect relatable, no-holds-barred dialogue, actionable coping strategies, and a sense of shared experience that makes difficul... more
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Which podcasts are similar to this podcast?
These podcasts share a similar audience with this podcast:
1. Let's Talk Off Camera with Kelly Ripa
2. Reclaiming with Monica Lewinsky
3. Literally! With Rob Lowe
4. SmartLess
5. Howie Mandel Does Stuff Podcast
How many episodes of this podcast are there?
this podcast launched 2 years ago and published 133 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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What guests have appeared on this podcast?
Recent guests on this podcast include:
1. Bob Roth
2. Julie McFadden
3. Becca Tobin
4. Amanda Kloots
5. Kate Doerge
6. Myriam Sandler
7. Amy Kurtz
8. Tamsen Fadal
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