
On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.
| Publishes | Weekly | Episodes | 102 | Founded | 2 years ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | Personal JournalsHealth & FitnessSociety & Culture | |||

This week, Christina and Jamie are joined by their friend Kelly Ripa. They discuss Kelly's career and how it began at a toy fair, the processing she had to do while writing her own book, the challenges of playing yourself on television, and much more... more
This week, Christina and Jamie read listener emails and discuss skincare products from childhood, crazy animal stories, not thinking too far into the future, and much more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bre... more
This week, Christina and Jamie read listener emails and discuss the Married... with Children reunion, catch up on their TV shows, Jamie opens up about a recent experience, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Al... more
This week, Christina and Jamie read listener emails and discuss MS fatigue, finding little moments of self care, how to better communicate with friends, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Aud... more
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I am about a year behind and listening to episodes. So I don’t know what’s happening with you right now, but I’m so grateful you’ve been sharing your experience. My sister and I both have neurogenic POTS, which has led to a lifetime of dysautonomia, due to late diagnoses. Listening to share your experiences, has helped keep me stay sane. The compassion you show for one another is very special. I hope that we all can have friends who listen to us and except who we are. Thank you for reminding me ... more
I don’t have MS but I do live with chronic pain that affects my daily life and relationships. I look forward to each new episode for validation, inspiration, insight and a few laughs. Thank you so much for sharing your raw and honest feelings and stories. It helps so, so much. So much love and admiration to you both ❤️
MeSsy is the bestest of the restest
podcast, who knew MS is the thing that can rival every chronic illness I ever heard of?I don’t have MS, only severe, reactive arthritis, which has some underlying cause nobody knows, but causes pain, mobility and movement limitations, anxiety, affects body weight, and it doesn’t cover a fraction of the symptoms Christina and Jamie Lynne deal with, and from a much younger age! I used to work with folks with MS, helping them get Attendant Care, and I wish I knew... more
I love your show and how honest you both are!
Love your podcast. I appreciate your honesty. I don’t have MS, but I have been “living” with chronic pain (etc) conditions for over 20 years. It has been overwhelming and exhausting.
Key themes from listener reviews, highlighting what works and what could be improved about the show.
How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.
Apple Podcasts | #3 | |
Apple Podcasts | #86 | |
Apple Podcasts | #5 | |
Apple Podcasts | #27 | |
Apple Podcasts | #75 | |
Apple Podcasts | #211 |
Recent interactions between the hosts and their guests.
Listeners, social reach, demographics and more for this podcast.
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This show focuses on the candid experiences of two hosts living with multiple sclerosis (MS), exploring not only their personal struggles but also the broader emotional landscape of living with chronic illness. Episodes frequently feature their humorous yet heartfelt conversations that touch on topics such as coping strategies, community support, parenting challenges, and the importance of vulnerability. The hosts also engage with a variety of guests, including celebrities and experts, to discuss health and wellness, creating a diverse tapestry of insights that resonate with listeners navigating their own life challenges. Unique in its blend of humor and raw honesty, the content often provides a sense of belonging and understanding for thos... more
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1. Let's Talk Off Camera with Kelly Ripa
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this podcast launched 2 years ago and published 102 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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Recent guests on this podcast include:
1. Kelly Ripa
2. Bobbi Brown
3. Dr. Will Cole
4. Meg Josephson
5. Rob Iler
6. Craig Thomas
7. Baylen Dupree
8. Megan Mullally
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