
On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.
| Publishes | Weekly | Episodes | 105 | Founded | 2 years ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | Personal JournalsHealth & FitnessSociety & Culture | |||

This week, Christina and Jamie are joined by Carl Radke, Summer House cast member and host of "More Life with Carl Radke.” They discuss his journey to sobriety, holding in shame, forgiveness, behind-the-scenes of the show, and more.
Executive Produ... more
This week, Christina and Jamie are joined by Jamie’s friend Ryan Weiss. They discuss how he helped her through a difficult time, the power of dance, emotional avoidance, why it’s so hard to look inward, and more.
Check out Ryan's course "How to Be O... more
This week, Christina and Jamie read listener emails and discuss the fragility of life, fighting against your body, and more,
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episo... more
This week, Christina and Jamie are joined by their friend Kelly Ripa. They discuss Kelly's career and how it began at a toy fair, the processing she had to do while writing her own book, the challenges of playing yourself on television, and much more... more
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Just got turned on to the podcast and I’m loving it! You both are my warriors! It’s been a tough year and so
Many infusions! I’m leaning on positivity! I’m very fortunate to have a wonderful and caretaker! My goal is to walk without my stick at at our daughters wedding in Greece
And fly fishing with my dad! Good days and bad! Getting through each day!!
I just listened to the Ryan Weiss episode- ladies, i love your podcast and all the guests you bring on but what I truly love is how real you both are about life. Thank you for being you and thank you for this podcast.
Being open about the struggles we face can be great, but unfortunately, that doesn’t mean we have to like you. Being ill is never an excuse to be mean or rude. I feel bad for others who have to deal with your behavior on a daily basis, especially minors.
While I do not have MS or any type of debilitating condition, I love this podcast. I love Christina and Jamie and how real they are. The guests are great, but I also love the episodes where they take listener comments. This is my must listen to weekly!
I love this podcast. Jamie is truly gifted in talking compassionately to guests and callers, and in raising awareness about MS. I have learned so much from her and Christina. However, I feel as if Christina has become increasingly bitter, defiant, rude, and just mean sometimes. I do not wish to hurt her feelings. Recently, she spent a bit of time justifying her constant interruptions, saying that they were “conversations.” This is incorrect, they are interruptions. She will blatantly interrupt p... more
Key themes from listener reviews, highlighting what works and what could be improved about the show.
How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.
Apple Podcasts | #9 | |
Apple Podcasts | #171 | |
Apple Podcasts | #13 | |
Apple Podcasts | #65 | |
Apple Podcasts | #201 | |
Apple Podcasts | #35 |
Recent interactions between the hosts and their guests.
Listeners, social reach, demographics and more for this podcast.
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Exploring the challenges of living with chronic illnesses, particularly multiple sclerosis (MS), the conversations often highlight themes of vulnerability, friendship, and self-advocacy. The hosts, both of whom share their personal experiences with MS, engage in candid discussions that resonate with listeners dealing with similar struggles. Episodes feature a mix of humor and heartfelt connection, as they navigate the ups and downs of daily life, family obligations, and the entertainment industry, often bringing in diverse guests who share valuable insights related to health and wellness. Unique to this show is the evident chemistry between the hosts, which enhances the authenticity and relatability of their narratives, making it a go-to re... more
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1. Let's Talk Off Camera with Kelly Ripa
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3. Literally! With Rob Lowe
4. Reclaiming with Monica Lewinsky
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this podcast launched 2 years ago and published 105 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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Recent guests on this podcast include:
1. Ryan Weiss
2. Martha Plimpton
3. Susan Appleby
4. Kelly Ripa
5. Bobbi Brown
6. Dr. Will Cole
7. Meg Josephson
8. Deb Dana
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