Artwork for MeSsy with Christina Applegate & Jamie-Lynn Sigler

MeSsy with Christina Applegate & Jamie-Lynn Sigler

Wishbone Production

On this podcast, Christina Applegate and Jamie-Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

PublishesWeeklyEpisodes10Founded2 months ago
Number of ListenersCategories
Personal JournalsComedySociety & Culture

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Artwork for MeSsy with Christina Applegate & Jamie-Lynn Sigler

Latest Episodes

This week, Christina and Jamie open up about their battles with eating disorders and self-esteem. They reflect on the moments that changed their lives, and discuss body dysmorphia, societal conditioning, how they each got to a healthier place, and mo... more

5 days ago

This week, Christina and Jamie discuss giving up control, feeling judgement, and Jamie shares how she knew to get tested for MS. They also answer some listener questions. more

12 days ago

This week, Christina and Jamie are joined by their friend, Jimmy Kimmel. They discuss finding humor in tough situations, the things he still wants to accomplish, speaking from your heart, mean tweets, and much more. more

19 days ago

This week, Christina and Jamie discuss feeling obligated to be strong, the importance of being there for each other, wearing diapers, and much more. They also answer some listener questions. more

a month ago


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4.9 out of 5 stars from 3.6k ratings
  • Great listen

    I appreciate the honesty and humor of this podcast. Both of you are amazingly strong women, keep it coming. We are all going through something. Thank you for sharing your truth.

    Apple Podcasts
    United Statesa month ago
  • Loving this

    Been listen to all of your recent podcasts and think they are absolutely amazing. I am the wife of a wonderful man who has unfortunately been affected by MS. I have watched his personality change at times and seen him go through so much. It’s tough as an outsider to see the person you love transform and yes sometimes be very angry! It’s so helpful to hear your insight and feelings and most of all your honesty! This podcast will help so many. Not only those with MS, those who love and care for pe... more

    Apple Podcasts
    United Statesa month ago
  • Love the honest talk!

    Diagnosed 20 years ago at 30, at 40 was diagnosed with PPMS. I had my twins at 38, and my youngest son at43, and being an older mom has been both difficult and a blessing. I am calmer, don’t sweat the small stuff, and appreciate each day. My kids are so compassionate and emotionally intelligent for witnessing my flaws, slurs, fall downs, humiliations, cognitive blank stares, and through all that love and disappointment I am grateful to be alive, albeit going at a different pace. Looking back I w... more

    Apple Podcasts
    United Statesa month ago
  • Thank you ladies

    I find this podcast so comforting. I love hearing your experiences about travel. Ive had MS for 17 years and travel can be so tricky. Long flights are tricky. As far as traveling somewhere hot , I never do thing I love to do is go to my vacation home on Hilton head Island because you can bike on the sand at low tide.the sand is hard packed enough for your bike to go but in the event you fall it doesn’t hurt so bad or at all. My suggestion to Christina is find a town like that and bike y... more

    Apple Podcasts
    United Statesa month ago
  • Top Notch Podcast

    You two are true souls. I’m a 64 year old woman that just liked your acting and wanted to listen to Messy. I have learned so much! Not only about MS but also how those of us not affected can be more supportive and empathetic toward you. Love you both! Keep up the good work gals!!❤️ Kim

    Apple Podcasts
    United Statesa month ago


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this podcast launched 2 months ago and published 10 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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