
On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.
| Publishes | Weekly | Episodes | 109 | Founded | 2 years ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | Health & FitnessPersonal JournalsSociety & Culture | |||

This week, Jamie is joined by her two best friends, Becca Tobin and Odette Annable. They discuss navigating friendships in all seasons of life, giving grace to yourself and others, finding your people, and more.
Executive Producers: Christina Appleg... more
This week, Jamie is joined by her husband, Cutter Dykstra. They discuss his experience as her partner and caregiver, the role he's played in Jamie's acceptance and outlook, advice for other partners, and more.
Executive Producers: Christina Applega... more
We’re taking a short break for the next few weeks while Jamie and Christina focus on their book launches. We’ll be back soon with brand new episodes!
This week, Christina and Jamie are joined by Olivia Munn. They discuss Olivia’s breast cancer diagnosis, how she was finally able to shed her armor, why you shouldn’t tell someone going through something to look on the bright side, and more.
Executi... more
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I just listened to the Kelly Ripa interview and loved it very much. I enjoy watching Kelly and Mark every morning and their host chat segments at the beginning. I've enjoyed Kelly Ripa's book, Christina's book, and I will make sure to get Jamie's when it comes out. I enjoy Kelly and Christina's humor and it explains why I crushed on them and also wrote letters to them and they both replied to me. With Christina it was sharing my poems with her and Kelly it was musical instruments. We both had ... more
Just thank you. I’m not here to write you my situation. But know you’ve helped me.
I don't have MS but I live with multiple chronic illnesses and pain. It's extremely lonely and difficult, especially being housebound most days and let's face it normal people just don't understand the pain and reality of living like this. I really appreciate this podcast, it makes me feel less alone. Please keep this up as long as you can, even if it isn't always talking about illness. ❤️
I started listening to the show because I’m a fan of Christina Applegate. There are many reasons to listen to the show. Information and support for MS, entertaining interviews and real talk from two amazing women.
Thank you so damn much for explaining all of these difficult things to women who have been gaslit and told they are nuts, by docs and family members. I have 3 nursing degrees including a masters degree and was never taught about auto immune disorders/diseases. Thank you for helping people understand in a non-judgmental way. Thank you for allowing people to be seen and feel included. I’m a mental health nurse and professor with 5 auto immune diseases including Sjogrens, and I cannot get through m... more
Key themes from listener reviews, highlighting what works and what could be improved about the show.
How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.
Apple Podcasts | #15 | |
Apple Podcasts | #225 | |
Apple Podcasts | #20 | |
Apple Podcasts | #58 | |
Apple Podcasts | #222 | |
Apple Podcasts | #38 |
Recent interactions between the hosts and their guests.
Listeners, social reach, demographics and more for this podcast.
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Exploring the challenges of living with chronic illnesses, particularly multiple sclerosis (MS), the conversations often highlight themes of vulnerability, friendship, and self-advocacy. The hosts, both of whom share their personal experiences with MS, engage in candid discussions that resonate with listeners dealing with similar struggles. Episodes feature a mix of humor and heartfelt connection, as they navigate the ups and downs of daily life, family obligations, and the entertainment industry, often bringing in diverse guests who share valuable insights related to health and wellness. Unique to this show is the evident chemistry between the hosts, which enhances the authenticity and relatability of their narratives, making it a go-to re... more
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1. Let's Talk Off Camera with Kelly Ripa
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3. Dear Chelsea
4. Literally! With Rob Lowe
5. Armchair Expert with Dax Shepard
this podcast launched 2 years ago and published 109 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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Recent guests on this podcast include:
1. Olivia Munn
2. Carl Radke
3. Ryan Weiss
4. Martha Plimpton
5. Susan Appleby
6. Kelly Ripa
7. Bobbi Brown
8. Dr. Will Cole
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