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Artwork for MeSsy with Christina Applegate & Jamie Lynn Sigler

MeSsy with Christina Applegate & Jamie Lynn Sigler

Wishbone Production
Multiple Sclerosis
Mental Health
Friendship
Chronic Illness
Therapy
Parenting Challenges
Emotional Support
Vulnerability
Health Struggles
Motherhood
Grief
Personal Struggles
Empathy
Support Systems
Chronic Illness Awareness
Body Image
Eating Disorders
Acting
Nurse Jackie
Cancer

On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

PublishesWeeklyEpisodes87Founded2 years ago
Number of ListenersCategories
Health & FitnessPersonal JournalsSociety & Culture

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Artwork for MeSsy with Christina Applegate & Jamie Lynn Sigler

Latest Episodes

This week, Christina and Jamie are joined by Robert Iler, who starred on "The Sopranos" with Jamie. They discuss memories from their time on the show, his path to becoming sober, his friendship with Jamie, and much more.

Executive Producers: Christi... more

This week Christina and Jamie are joined by Craig Thomas, an author and  Co-Creator, Executive Producer and Writer of How I Met Your Mother. He shares his experience raising a son with Jacobsen Syndrome, discusses the power of storytelling to make pe... more

YouTube

This week, Christina and Jamie read listener emails and discuss aging, being able to express emotions authentically, where to turn when you’re feeling stuck, and more.

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick... more

YouTube

This week, Christina and Jamie read listener emails and discuss dynamic disability, not being alone in your struggles, the meaning we attach to things, and more.

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

Audi... more

YouTube

Key Facts

Accepts Guests
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Contact Information
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Number of Listeners
Find out how many people listen to this podcast per episode and each month.

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Recent Guests

Craig Thomas
Emmy-nominated producer and writer, creator of How I Met Your Mother
Episode: How Vulnerable Can I Be? with Craig Thomas
Baylen Dupree
A young woman living with Tourette syndrome, known for her openness and advocacy.
Beautifully Complex
Episode: It’s Okay to Be Yourself with Baylen Dupree
Megan Mullally
Actor and singer, best known for her role as Karen Walker on Will & Grace.
Episode: Megan Mullally
Cindy Locke
A fellow MS warrior and friend of Christina who shares her personal experiences with MS.
Episode: Do What You Can When You Can
Fraser Olender
Star of Below Deck and Chief Stew
Below Deck
Episode: Fraser Olender
Dr. Daniel Amen
Popular psychiatrist, CEO of Amen Clinics, author, and researcher.
Amen Clinics
Episode: Change Your Brain, Change Your Pain with Dr. Daniel Amen
Ed Helms
Actor and comedian known for roles in The Office and The Hangover
Episode: Ed Helms
Dr. Gretchen Hawley
Physical therapist and MS certified specialist
Episode: Any Movement Counts with Doctor Gretchen
Clea Shearer
Co-founder of The Home Edit and breast cancer survivor
The Home Edit
Episode: Clea Shearer

Hosts

Christina Applegate
Co-host of a personal and heartfelt podcast discussing health and life experiences, particularly focusing on multiple sclerosis (MS).
Jamie Lynn Sigler
Co-host and one of the key voices in discussing real-life challenges, including living with MS and other personal experiences.

Reviews

4.9 out of 5 stars from 5.7k ratings
  • MS is a just delightful mess

    I just love listening to y’all on the podcast! I currently take Ocrevus which an infusion that I receive every 6 months. My brother and I both have MS, I am 52 and he is 55. I was 21 when I got blessed with the monster, he did not “catch” it until about 8 years ago! There were no medications available at first but I’ve taken probably about 4 others before landing on Ocrevus. My MS is visible as I use a walker or scooter to get around. My brother gets vision problems from his! I get UTIs oftentim... more

    Apple Podcasts
    5
    sgschoel
    United Statesa month ago
  • Love this podcast so much!

    MeSsy has become my favorite podcast. At this point it’s the only one I listen to until I can catch up on all the episodes.

    I don’t have MS or a chronic illness but I get so much out of it. It’s helped me recover from major surgery, be more aware of what others deal with on an ongoing basis, and laugh and cry with Christina and Jamie in all of their brilliant, vulnerable glory. Kudos to these two women for being willing to go there especially in an industry that can be so focused on appearan... more

    Apple Podcasts
    5
    school4joy
    United Statesa month ago
  • Informative and Offensive

    Not even one minute into the podcast, you’re sure to hear Christina Applegate drop an f-bomb, and these are sprinkled throughout the podcast. I like the content, the relationship between the hosts, and the valuable information I get here, but the profanity has become so offensive and it is on every episode. Can’t two intelligent, compassionate women come up with an alternative to this word that has become so pervasive?

    Apple Podcasts
    4
    Janet V66
    United States2 months ago
  • Freaking love this Podcast!!

    This podcast has made such a huge difference in my life! I love the connection between Christina and Jamie and truly feel like they are speaking to me on every episode. I was diagnosed with RRMS in 2008 and am now on disability. I am a 42 year old Mother and Grandmother who is still trying to find my new normal with all of these life changes. I always feel a lot better after listening to your show even though sometimes I will cry while I am laughing. Both of you are so open and raw about how you... more

    Apple Podcasts
    5
    Jamie Lee☮️🧡
    United States2 months ago
  • You are for real

    I just found this podcast as I am living with cronic pain, waiting to be diagnosed maybe with ms, I don’t know… however listen to you guys it’s like a relief because I don’t feel alone, even when the waiting to be diagnosed is overwhelming. Thank you for being you and for showing as you are, we need more of this as we are all humans and vulnerability is a super power. Life is messy, and sweet at the same time! Keep going!

    Apple Podcasts
    5
    Paola Canada
    Canada2 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Listeners commend the raw honesty that the hosts exhibit, particularly regarding their health struggles, which helps destigmatize mental and physical health challenges.
Many find the dynamic between Christina and Jamie Lynn to feel like a conversation between close friends, which resonates deeply with their audience.
The hosts create a genuinely supportive and humorous environment, making listeners feel connected and understood. People appreciate the relatable discussions surrounding chronic illness and parenting.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

How Vulnerable Can I Be? with Craig Thomas
Q: What was it like navigating the challenges you faced as a parent?
Craig shares insights into the emotional rollercoaster of raising a child with Jacobson Syndrome, emphasizing the importance of community and advocacy in overcoming challenges.
It’s Okay to Be Yourself with Baylen Dupree
Q: What advice would you give to anyone that might be listening to this that has Tourette's or thinks they have Tourette's?
To not feel alone. We're so much more alike than we are different.
Fraser Olender
Q: What has been the hardest thing about being on television?
Fraser states that being on television has been the hardest and most doubted decision of his life, pushing him into maturity and forcing him to confront public perception.
Fraser Olender
Q: How did you end up on Below Deck?
Fraser explains that he was a model agent before entering yachting, and a casting director from Below Deck found him and convinced him to join the show.
Fraser Olender
Q: Who was little Fraser growing up in England?
Fraser describes himself as incredibly shy and scared and a bit lost, often struggling with his identity and sexuality.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
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Frequently Asked Questions About This Podcast

What is This Podcast about and what kind of topics does it cover?

This podcast offers an authentic and heartfelt exploration of life's challenges, particularly focusing on the experiences of living with multiple sclerosis (MS). The hosts, who candidly discuss their personal struggles and triumphs, foster a sense of community through their shared vulnerabilities. Topics often revolve around relationships, parenting, and the emotional toll of chronic illness, ensuring listeners feel understood and supported. Unique in its blend of humor and sincerity, each episode invites guests from various backgrounds, making it relatable to anyone grappling with life's unexpected difficulties. The hosts aim to inspire resilience and promote open conversations about pain, mental health, and personal growth, encouraging li... more

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These podcasts share a similar audience with this podcast:

1. Let's Talk Off Camera with Kelly Ripa
2. Sibling Revelry with Kate Hudson and Oliver Hudson
3. Reclaiming with Monica Lewinsky
4. Dear Chelsea
5. Literally! With Rob Lowe

How many episodes of this podcast are there?

this podcast launched 2 years ago and published 87 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on this podcast?

Recent guests on this podcast include:

1. Craig Thomas
2. Baylen Dupree
3. Megan Mullally
4. Cindy Locke
5. Fraser Olender
6. Dr. Daniel Amen
7. Ed Helms
8. Dr. Gretchen Hawley

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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