Rephonic
Artwork for MeSsy with Christina Applegate & Jamie Lynn Sigler

MeSsy with Christina Applegate & Jamie Lynn Sigler

Wishbone Production
Multiple Sclerosis
Mental Health
Friendship
Chronic Illness
Therapy
Parenting Challenges
Emotional Support
Vulnerability
Health Struggles
Grief
Motherhood
Personal Struggles
Support Systems
Empathy
Chronic Illness Awareness
Body Image
Eating Disorders
Acting
Cancer
The Sopranos

On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

PublishesWeeklyEpisodes105Founded2 years ago
Number of ListenersCategories
Personal JournalsHealth & FitnessSociety & Culture

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Artwork for MeSsy with Christina Applegate & Jamie Lynn Sigler

Latest Episodes

This week, Christina and Jamie are joined by Carl Radke, Summer House cast member and  host of "More Life with Carl Radke.” They discuss his journey to sobriety, holding in shame, forgiveness, behind-the-scenes of the show, and more.

Executive Produ... more

YouTube

This week, Christina and Jamie are joined by Jamie’s friend Ryan Weiss. They discuss how he helped her through a difficult time, the power of dance, emotional avoidance, why it’s so hard to look inward, and more.

Check out Ryan's course "How to Be O... more

YouTube

This week, Christina and Jamie read listener emails and discuss the fragility of life, fighting against your body, and more,

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

Audio Engineer: Josh Windisch

This episo... more

YouTube

This week, Christina and Jamie are joined by their friend Kelly Ripa. They discuss Kelly's career and how it began at a toy fair, the processing she had to do while writing her own book, the challenges of playing yourself on television, and much more... more

YouTube

Key Facts

Accepts Guests
Accepts Sponsors
Contact Information
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Number of Listeners
Find out how many people listen to this podcast per episode and each month.

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Recent Guests

Ryan Weiss
Coach, writer, speaker discussed in interview
Episode: How to Heal Your Relationship With Life
Martha Plimpton
Actor mentioned as hosting guest on the episode
Episode: We Don’t Want to Be Defined by This
Susan Appleby
Character connection from a show; discussed in dialogue
Episode: We Don’t Want to Be Defined by This
Kelly Ripa
Mogul and media superstar
Ripa Productions
Episode: Kelly Ripa
Bobbi Brown
World-renowned makeup artist, beauty industry trailblazer, and founder of Jones Road Beauty.
Jones Road Beauty
Episode: Bobbi Brown
Dr. Will Cole
Functional medicine expert and New York Times bestselling author
Episode: The Impact of Inflammation with Dr. Will Cole
Meg Josephson
Psychotherapist, licensed clinical social worker, and author
Self
Episode: Are You Mad At Me? with Meg Josephson
Deb Dana
Clinician, consultant, author of many books, international lecturer on polyvagal informed work with trauma survivors.
Polyvagal Institute
Episode: How to Feel Safe in Your Body with Deb Dana (Re-Release)
Rob Iler
Actor known for his role in The Sopranos
Episode: Robert Iler

Hosts

Christina Applegate
Co-host of MeSsy, known for her candid discussions about living with multiple sclerosis and her journey in acting and personal growth.
Jamie Lynn Sigler
Co-host of MeSsy, shares her personal experiences with multiple sclerosis and engages in heartfelt discussions on health and wellbeing.

Reviews

4.9 out of 5 stars from 5.8k ratings
  • MS and CIDP

    Just got turned on to the podcast and I’m loving it! You both are my warriors! It’s been a tough year and so

    Many infusions! I’m leaning on positivity! I’m very fortunate to have a wonderful and caretaker! My goal is to walk without my stick at at our daughters wedding in Greece

    And fly fishing with my dad! Good days and bad! Getting through each day!!

    Apple Podcasts
    5
    NickieK09
    United States8 days ago
  • All the love

    I just listened to the Ryan Weiss episode- ladies, i love your podcast and all the guests you bring on but what I truly love is how real you both are about life. Thank you for being you and thank you for this podcast.

    Apple Podcasts
    5
    Jamie7681
    United States11 days ago
  • Unlikable

    Being open about the struggles we face can be great, but unfortunately, that doesn’t mean we have to like you. Being ill is never an excuse to be mean or rude. I feel bad for others who have to deal with your behavior on a daily basis, especially minors.

    Apple Podcasts
    1
    RunFarAwayCopper
    United States18 days ago
  • A Must Listen to for Me

    While I do not have MS or any type of debilitating condition, I love this podcast. I love Christina and Jamie and how real they are. The guests are great, but I also love the episodes where they take listener comments. This is my must listen to weekly!

    Apple Podcasts
    5
    Jules22and12
    United States19 days ago
  • Lovely except

    I love this podcast. Jamie is truly gifted in talking compassionately to guests and callers, and in raising awareness about MS. I have learned so much from her and Christina. However, I feel as if Christina has become increasingly bitter, defiant, rude, and just mean sometimes. I do not wish to hurt her feelings. Recently, she spent a bit of time justifying her constant interruptions, saying that they were “conversations.” This is incorrect, they are interruptions. She will blatantly interrupt p... more

    Apple Podcasts
    4
    Sequatchiee43
    United States19 days ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Many find the topics discussed relatable and supportive, often sharing how it has helped them feel less alone.
Some suggest that the inclusion of more expert guests could enhance the content's depth and relevance.
The chemistry between the hosts is often highlighted as a major strength of the show.
Listeners appreciate the raw and honest conversations about living with chronic illness.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

The Impact of Inflammation with Dr. Will Cole
Q: Would you advise to begin in one area or the other, start slow because there's a lot of pitfalls?
It's important to meet patients where they're at and start with a plan they can consistently follow, focusing on manageable changes.
The Impact of Inflammation with Dr. Will Cole
Q: Can you just actually talk about what inflammation is? What is happening in the body?
Dr. Cole discusses the necessity of inflammation for bodily functions but emphasizes the problems caused by chronic inflammation and the importance of identifying underlying causes.
How Vulnerable Can I Be? with Craig Thomas
Q: What was it like navigating the challenges you faced as a parent?
Craig shares insights into the emotional rollercoaster of raising a child with Jacobson Syndrome, emphasizing the importance of community and advocacy in overcoming challenges.
It’s Okay to Be Yourself with Baylen Dupree
Q: What advice would you give to anyone that might be listening to this that has Tourette's or thinks they have Tourette's?
To not feel alone. We're so much more alike than we are different.
Fraser Olender
Q: What has been the hardest thing about being on television?
Fraser states that being on television has been the hardest and most doubted decision of his life, pushing him into maturity and forcing him to confront public perception.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
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Age Range
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Social Media Reach

Frequently Asked Questions About This Podcast

What is This Podcast about and what kind of topics does it cover?

Exploring the challenges of living with chronic illnesses, particularly multiple sclerosis (MS), the conversations often highlight themes of vulnerability, friendship, and self-advocacy. The hosts, both of whom share their personal experiences with MS, engage in candid discussions that resonate with listeners dealing with similar struggles. Episodes feature a mix of humor and heartfelt connection, as they navigate the ups and downs of daily life, family obligations, and the entertainment industry, often bringing in diverse guests who share valuable insights related to health and wellness. Unique to this show is the evident chemistry between the hosts, which enhances the authenticity and relatability of their narratives, making it a go-to re... more

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Which podcasts are similar to this podcast?

These podcasts share a similar audience with this podcast:

1. Let's Talk Off Camera with Kelly Ripa
2. Sibling Revelry with Kate Hudson and Oliver Hudson
3. Literally! With Rob Lowe
4. Reclaiming with Monica Lewinsky
5. Dear Chelsea

How many episodes of this podcast are there?

this podcast launched 2 years ago and published 105 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on this podcast?

Recent guests on this podcast include:

1. Ryan Weiss
2. Martha Plimpton
3. Susan Appleby
4. Kelly Ripa
5. Bobbi Brown
6. Dr. Will Cole
7. Meg Josephson
8. Deb Dana

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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