
On The Pen is the leading GLP-1 news podcast and platform covering obesity medicine, FDA actions, drug shortages, access policy, and the business of NuSH therapies. The podcast is in the top 0.5% of all podcasts globally, and On The Pen is a top Substack best-seller.
| Publishes | Weekly | Episodes | 216 | Founded | 3 years ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | MedicineHealth & Fitness | |||

What if the next big breakthrough in obesity medicine isn't a GLP-1 at all?
Novo Nordisk is developing an experimental oral weight-loss medication called LX9851, an ACSL5 inhibitor that targets an entirely different biological pathway than Ozempic, ... more
Retatrutide’s New Phase 3 Data, CagriSema in Menopause, and the Growing GLP‑1 Access CrisisHost Dave Knapp recaps major obesity-drug updates, focusing on Eli Lilly’s triple agonist retatrutide and Novo Nordisk’s CagriSema. He reviews Triumph 1 obesit... more
Specific lots of compounded tirzepatide have been recalled over sterility concerns, another pharmacy recently recalled compounded semaglutide after particulate matter was identified, patients have reported visible strands and fibers in other compound... more
Eli Lilly’s fight over retatrutide may be about much more than one obesity drug.I’ve been covering retatrutide since early 2023, and since late 2024 I’ve been closely following the legal fight over whether reta should be treated as a biologic. From t... more
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Generally speaking the information is pretty good and it’s how I keep up to date with related news, but the audio quality is a huge turn off. The intro and outro music is much much louder than the rest of the podcast, and the AI voice is obnoxious. Audio of the podcast itself is hit or miss, sometimes there are a lot of audio issues sometimes there aren’t any aside from the loud music.
Dave has allowed me to better understand how the GLP-1 medication works.
He has also given me and others knowledge on how to better ask informed questions of our medical professionals while advocating for ourselves in an informed manner.
Dave and Ann work as a team and bring information on overall health and wellbeing. If you have read this far please joins us for a live podcast the group and chat are wonderful caring individuals.
Ruben
This show delivers the best insight in the GLP-1 realm of healthcare. I have learned so much from Dave and his Sister. I appreciate that he is a patient as well as an educator. Him being a man also helps men feel comfortable in the weight management area of healthcare which is not commonly a comfortable place for men. Watch it live once and you will never want to miss a live again! Subscribe and join immediately to help reach more people so more understand that obesity is a chronic health condit... more
On the Pen with Dave Knapp is tops on up-to-date sources of legislation, insurance issues, latest medical advancements, and helpful hints for anyone on a glp1 medication (and even their loved ones). I highly recommend this podcast!
Thank you for all you do!
Key themes from listener reviews, highlighting what works and what could be improved about the show.
How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.
Apple Podcasts | #37 | |
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Apple Podcasts | #140 | |
Apple Podcasts | #85 | |
Apple Podcasts | #204 | |
Apple Podcasts | #47 |
Recent interactions between the hosts and their guests.
Listeners, social reach, demographics and more for this podcast.
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Timely, patient-focused coverage of GLP-1 medicines and the wider field of obesity treatment. Dave Knapp explains clinical trial results, emerging therapies, drug safety, FDA actions, compounding and supply-chain developments, and the insurance and policy decisions that shape access. The format is primarily host-led analysis, with occasional guest commentary, translating technical findings and industry news into practical context for patients and healthcare professionals.
A distinctive focus is the connection between drug development and everyday consequences: affordability, coverage, treatment decisions, and the risks created when approved medicines are hard to obtain. The coverage weighs promising results against safety limits and uncert... more
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These podcasts share a similar audience with On The Pen GLP-1 News:
1. GLP-1 Hub: Support, Community, and Weight Loss
2. A GLP-1 Guide to Metabolic Health: The Plus SideZ Podcast
3. The Obesity Guide with Matthea Rentea MD
4. The GLP-1 Podcast Show
5. The Holistic GLP-1 Podcast with Elizabeth McGann
On The Pen GLP-1 News launched 3 years ago and published 216 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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Recent guests on On The Pen GLP-1 News include:
1. Dr. Angela K. Fitch
2. Jen Kanush
3. David White
4. Beverly Chang
5. Jen Kinnoosh
6. Kyler Ockey
7. Sabina Hemmi
8. Spencer Nadolsky
To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.