Rephonic
Artwork for On The Pen GLP-1 News
Glp-1 Medications
Eli Lilly
Glp-1
Zepbound
Obesity
Novo Nordisk
Mounjaro
Wegovy
FDA
Terzepatide
Diabetes
Retatrutide
Obesity Medicine
Ozempic
Semaglutide
Weight Loss
Cagrisema
Medicare
Obesity Treatment
Type 2 Diabetes

On The Pen is the leading GLP-1 news podcast and platform covering obesity medicine, FDA actions, drug shortages, access policy, and the business of NuSH therapies. The podcast is in the top 1% of all podcasts globally, and On The Pen is a top Substack best-seller.

PublishesTwice weeklyEpisodes195Founded2 years ago
Number of ListenersCategories
MedicineHealth & Fitness

Listen to this Podcast

Artwork for On The Pen GLP-1 News

Latest Episodes

Dave sits down with nurse practitioner and former Retatrutide clinical trial participant David White to break down the biggest obesity headlines from the 2026 American Diabetes Association Conference. Together, they explore the latest data on Retatru... more

Dave breaks down an unreported Expanded Access Pathway that Eli Lilly has quietly established for Retatrutide.

Does Eli Lilly already have the solve for obesity? In this episode of On the Pen — the Weekly Dose Podcast, host Dave Knapp breaks down a stunning comment from Lilly's Chief Scientific Officer Daniel Skowronski, who suggested that obesity could becom... more

Key Facts

Accepts Guests
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Contact Information
Podcast Host
Number of Listeners
Find out how many people listen to this podcast per episode and each month.

Recent Guests

David White
Nurse practitioner with deep involvement in GLP-1 trials and data analysis; self-described retatrutide glucagon nerd
Michigan, USA
Episode: Retatrutide Just Reached Bariatric Surgery Results
Beverly Chang
Endocrinologist, obesity specialist
Episode: Retatrutide, Multi Agonist Obesity Drugs, and the PBM Access War
Jen Kinnoosh
Expert following GLP-1 studies and obesity medications; active member of On The Pen community
Episode: The Next Two Weeks in GLP1 Are Huge, Here's Why
Kyler Ockey
Chief Product Officer at Shed
Shed
Episode: He Took Retatrutide 40mg and Proved a Point
Sabina Hemmi
Expert commentator from GLP-Winner
GLP-Winner
Episode: BPI STOPS TIRZEPATIDE Production, Second Major Pharmacy Out!
Spencer Nadolsky
Board-certified obesity medicine doctor
Vineyard (clinic)
Episode: Ozempic Personality With Dr Spencer Nadolsky
Dr. Ian Ellis
Physician and founder of VoaFit, ER physician
VoaFit
Episode: Zepbound Dosing: What Your Doctor Didn't Explain
Shantanu Gaur
CEO of Allurion, a company pioneering non-surgical obesity treatments
Allurion
Episode: GLP-1 PLUS Gastric Balloon for added Weight Loss!
Sabina Hemme
Founder of GLP Winter, a company that helps patients compare access options for GLP-1 medications
GLP Winter
Episode: GLP-1 Compound Legislation: States are the Next Battlefield w/ Sabina Hemme

Host

Dave Knapp
Host of On The Pen GLP-1 News; frequent presenter on GLP-1 market and policy topics; links with obesity medicine and access discussions.

Reviews

4.9 out of 5 stars from 596 ratings
  • Health news

    I truly enjoy Dave bringing us the latest and greatest news when it comes to health and obesity news. He is so informative in this space.

    Apple Podcasts
    5
    Letiwilson
    United States2 months ago
  • Intelligent, current information

    Always relevant and timely. As a clinician, I appreciate Dave’s careful framing of the news he shares.

    Apple Podcasts
    5
    memesusan
    United States2 months ago
  • Always Important Info Here!

    I’ve listened to Dave’s On The Pen YouTube and podcast for years now and consider it a regular must listen for the ever changing world of all things GLP-1 type medications. He shares cutting edge science, breaking news and their real world implications, profound interviews as well as his personal experiences with GLP1 use. Hands down the best, most solid information out there in this sphere!

    Apple Podcasts
    5
    Sunshiny4
    United States2 months ago
  • Up to date news!

    Thank you Dave, for giving us the most up to date news in this space. How can we band together to rally for more affordable access? The middle class is still getting killed with drug costs and we need our current administration to see that?

    Apple Podcasts
    5
    JFair2
    United States3 months ago
  • Definitely recommend!

    Edit on 3.17.2026

    Yes I still follow Dave, he’s been keeping us updated on all the new peptides and all the new trials, he is fantastic! Nobody else has this important information and fights for advocacy, while keeping it real like Dave! Thank you for breaking down barriers to this life saving medication, and being honest with us! Grateful!

    I found Dave’s pod through his YouTube channel over the summer, and yes I’ve kept up with the ongoing craziness because of Dave. He shares lots of really im... more

    Apple Podcasts
    5
    TourGirl555
    United States3 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Dave Knapp is consistently seen as knowledgeable and trustworthy in GLP-1 news.
The show is praised for staying up-to-date and advocating for patient access during regulatory shifts.
Guests often highlight the host's ability to connect clinical relevance with market dynamics.
Listeners value the data-driven approach and clear explanations of complex policy.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Retatrutide Just Reached Bariatric Surgery Results
Q: How did retatrutide affect lipid profiles and inflammatory markers, and what does that imply for cardiovascular risk?
Triglycerides dropped around 40%, LDL reductions were substantial and likely greater than other incretin therapies, and hsCRP fell by roughly 60%, collectively indicating meaningful cardiovascular risk reduction beyond weight loss.
Retatrutide Just Reached Bariatric Surgery Results
Q: What were the key weight-loss findings in Triumph One at 80 weeks across the dose arms?
Four milligrams yielded about 19% weight loss, nine milligrams about 26%, and twelve milligrams around 28%, with extension showing continued gains towards 30% for higher doses.
The Next Two Weeks in GLP1 Are Huge, Here's Why
Q: What are your expectations for the Transcend study in diabetics, and how could the results reshape weight-loss expectations across populations?
Transcend has shown substantial weight loss in diabetics with the 40-week data, and the curves without a plateau suggest continued potential; if the results hold, diabetics could see significantly higher weight loss than non-diabetics, which would drive more disease-specific expectations and possibly new combination strategies.
The Next Two Weeks in GLP1 Are Huge, Here's Why
Q: How might real-world titration and dose changes influence how physicians prescribe these meds compared with trial protocols?
Clinicians will likely adopt more individualized titration strategies, adjusting doses based on tolerability and response, rather than sticking to fixed high-dose regimens; this could mean earlier dose reductions or stepwise adjustments to maintain weight loss while minimizing side effects.
The Next Two Weeks in GLP1 Are Huge, Here's Why
Q: Jen, tell us about what data we should expect to see at the European Obesity Congress and ADA sessions regarding maintenance studies like Sermount Maintain and Attain Maintain.
We should see top-line and, potentially, more granular data including categorical outcomes by BMI, maintenance dose comparisons (max tolerated dose vs. 5 mg vs. placebo), and safety signals over extended periods to understand durability and tolerability across patient subgroups.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
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Frequently Asked Questions About On The Pen GLP-1 News

What is On The Pen GLP-1 News about and what kind of topics does it cover?

This show provides up-to-date, data-driven coverage of GLP-1 therapies, obesity medicine, FDA actions, drug access, and the evolving market landscape. Episodes mix regulatory shifts, pricing, and access with practical takeaways for clinicians, patients, and providers, often featuring medical experts, policy analysts, and industry commentators. A consistent strength is translating complex trial data and policy changes into actionable insights for real-world decision-making, with a clear focus on patient access and the business of obesity medicines. The format tends to blend quick news updates, in-depth market analysis, and expert perspectives, making it valuable for professionals tracking GLP-1 developments, sponsors seeking brand and though... more

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Which podcasts are similar to On The Pen GLP-1 News?

These podcasts share a similar audience with On The Pen GLP-1 News:

1. GLP-1 Hub: Support, Community, and Weight Loss
2. The Plus SideZ: A GLP-1 Guide to Metabolic Health
3. The Obesity Guide with Matthea Rentea MD
4. The Holistic GLP-1 Podcast with Elizabeth McGann
5. Your GLP-1 Bestie

How many episodes of On The Pen GLP-1 News are there?

On The Pen GLP-1 News launched 2 years ago and published 195 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on On The Pen GLP-1 News?

Recent guests on On The Pen GLP-1 News include:

1. David White
2. Beverly Chang
3. Jen Kinnoosh
4. Kyler Ockey
5. Sabina Hemmi
6. Spencer Nadolsky
7. Dr. Ian Ellis
8. Shantanu Gaur

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