Nucleotides

Angiotensin II receptor blockers (ARBs) are a class of antihypertensive medications that act on Angiotensin receptor I on vascular smooth muscles and adrenal glands, there by preventing the binding of Angiotensin II. This leads to a decrease in vasoc... more

ACE inhibitors are a class of medicines used in the treatment of hypertension. They block angiotensin converting enzyme and prevent angiotensin II production, thereby decrease blood pressure. Dry cough, angioedema, hypotension and hyperkalemia are co... more

Friedreich’s ataxia is an autosomal recessive condition caused due to expanded GAA repeats in the FXN gene present on chromosome 9.

Gaucher disease is an autosomal recessive condition wherein there is decreased glucocerebrosidase levels. This results in the build up of glucocerebroside in the lysosomes of macrophages which in turn accumulates in several tissues, causing damage to... more

Albinism is a recessive genetic disorder caused by mutation in the genes of any enzyme or protein taking part in melanin production. This condition causes a decrease or absence of melanin pigment, resulting in decreased skin, hair and eye pigmentatio... more

Von Hippel Lindau disease is an autosomal dominant genetic condition caused by mutation in the VHL gene found on chromosome number 3. This results in increased levels of HIF, platelet-derived and vascular endothelial growth factors, causing tumor dev... more

Tay-Sachs disease is a rare autosomal recessive condition that results from a mutation in HEX-A gene on chromosome 15 that leads to GM2 ganglioside build up within lysosomes in the neurons of CNS resulting in progressive symptoms of CNS degeneration ... more

Fabry disease is a rare genetic disorder that affects the X chromosome. It is caused by mutation in the GLA gene resulting in decreased alpha galactosidase A enzyme or alpha-gal A, leading to the buildup of large glycosphingolipids like Globotriaosyl... more