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Artwork for NeurologyLive® Mind Moments®

NeurologyLive® Mind Moments®

NeurologyLive
Multiple Sclerosis
Parkinson's Disease
Epilepsy
Narcolepsy
Gene Therapy
Alzheimer's Disease
Clinical Trials
Neurology
Donanemab
Duchenne Muscular Dystrophy
Amyotrophic Lateral Sclerosis
Clinical Guidelines
Restless Leg Syndrome
Neals Annual Meeting
Functional Seizures
FDA
Alzheimer Disease
Levodopa
Combination Therapy
American Academy Of Sleep Medicine

Mind Moments®, a podcast from NeurologyLive®, brings you exclusive interviews with experts in neurologic disorders. Listen in to hear the latest clinical and research updates from major medical conferences, as well as insights on the management of complex disorders, including epilepsy, migraine, Alzheimer disease, stroke, multiple sclerosis, Parkinson disease, and more. For more expert insight i... more

PublishesTwice monthlyEpisodes192Founded7 years ago
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Health & FitnessEducationMedicine

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Artwork for NeurologyLive® Mind Moments®

Latest Episodes

Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice.

In episode 171, “Fragile X Syndrome Day: Clinical Challenges, Care Strategies, and Emerging Therapies,”... more

Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice.

In this Mind Moments episode, Daniel Ontaneda, MD, PhD, professor of neurology at the Cleveland Clinic ... more

Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice.

In this Mind Moments episode, Grace Gombolay, MD, associate professor of pediatrics at Emory University... more

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Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice.

In this Mind Moments episode, Jessica Ailani, MD, director of the MedStar Georgetown Headache Center, d... more

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Recent Guests

Dr. Ontaneda
Neurologist; MS specialist
Mellen Center (assumed)
Episode: 170: Evaluating New MS Diagnostic Criteria in Atypical Presentations
Grace Gombolay
Neuroimmunologist
Emory University School of Medicine
Episode: 169: A Clinical Guide to Diagnosing and Managing ADEM
Varun Kannan
Neuroimmunologist
Emory University School of Medicine
Episode: 169: A Clinical Guide to Diagnosing and Managing ADEM
Jessica Ailani
Director of the MedStar Georgetown Headache Center
MedStar Georgetown Headache Center
Episode: 168: Analyzing Phase 2 Data for PACAP Targeting Therapy Bocunebart in Migraine
Todd Arnedt
Professor of psychiatry and neurology at Michigan Medicine-University of Michigan
University of Michigan
Episode: 167: New AASM Guidance on Combination Treatment for Chronic Insomnia
Scott Grossman
Assistant Professor of Neurology and Ophthalmology, NYU Grossman School of Medicine
New York University Grossman School of Medicine
Episode: 166: Understanding RNFL Asymmetry as a Biomarker in Pediatric MS
Greg Pontone
Chief of Aging, Behavioral and Cognitive Neurology at the University of Florida
University of Florida
Episode: 165: Addressing Cognitive Decline in Parkinson Disease
Julie Kurek
Associate Professor of Neurology at Augusta University
Augusta University
Episode: 164: Tremor vs Dyskinesia: Practical Bedside Clues for Clinicians
Dr. Sarah Hoffmann
Senior neurologist at Charité University Medicine, Berlin
Charité University Medicine, Berlin
Episode: 163: The Clinical Reality of Seronegative Myasthenia Gravis

Host

Marco Meglio
Host of Mind Moments podcast; editor at Neurology Live; frequently presents clinical updates and expert interviews.

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170: Evaluating New MS Diagnostic Criteria in Atypical Presentations
Q: What are the practical signals clinicians should look for in everyday practice to apply these criteria effectively?
Clinicians should use biomarkers like central vein sign and new lesion dissemination on MRI, along with clinical context, to determine if MS is likely, recognizing that treatment decisions depend on multiple factors beyond a positive diagnostic result.
170: Evaluating New MS Diagnostic Criteria in Atypical Presentations
Q: Can you explain how the 2024 criteria change the way we diagnose MS in patients who are asymptomatic or have non-specific symptoms?
The changes allow diagnosis based on imaging and specific biomarkers even when classic clinical attacks are not present, which increases diagnostic yield in technically eligible patients while emphasizing that diagnosis does not automatically dictate treatment and should be interpreted with clinical context.
168: Analyzing Phase 2 Data for PACAP Targeting Therapy Bocunebart in Migraine
Q: 804142: What are the things that you and your colleagues are making sure that you are trying to factor in when designing this trial? And also, what are some of the unknowns about a phase three trial with this type of drug that we haven't gotten to this point yet with the PAC-CAB targeting drugs?
Design focus includes defining the patient population most likely to show a robust response, clarifying prior treatment histories, anticipating potential interactions with CGRP therapies, and identifying meaningful endpoints beyond migraine days, such as patient-reported outcomes, while acknowledging uncertainties about long-term safety and optimal sequencing with other preventive therapies.
168: Analyzing Phase 2 Data for PACAP Targeting Therapy Bocunebart in Migraine
Q: 792762: You obviously, and I don't know how much detail you're going to be able to give about this, but just talk a little bit about what some of the considerations might look like for a potential phase three trial for this drug.
Key considerations include selecting whether chronic migraine patients or a broader refractory population should be enrolled, determining the necessary prior treatment exposure, incorporating predictors of responders, and planning how to evaluate combination therapy with anti-CGRP agents in a phase three setting to optimize efficacy signals while managing safety and variability in placebo response.
168: Analyzing Phase 2 Data for PACAP Targeting Therapy Bocunebart in Migraine
Q: 643022: So why in particular did you guys choose Ebrojapan out of all of them? Or was there really no major reason for that?
There wasn't a single decisive reason beyond practical alignment with acute treatment needs, recognizing that most patients on Bacunabart will require an acute option, and choosing a CGRP antagonist with a favorable pharmacokinetic profile makes logistical sense.

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Frequently Asked Questions About NeurologyLive® Mind Moments®

What is NeurologyLive® Mind Moments® about and what kind of topics does it cover?

Mind Moments features in-depth conversations with leading clinicians, researchers, and thought leaders in neurology. Episodes focus on clinical updates, guideline changes, and real-world practice across a range of neurological disorders—from sleep and epilepsy to stroke, movement disorders, and neurodegenerative diseases. Notable strengths include access to subject-matter experts who translate trials and conference findings into practical care insights, plus discussions that often touch on health equity, patient-centered outcomes, and evolving diagnostic and treatment paradigms. The format tends to mix expert commentary with practical tips for clinicians and care teams, making it valuable for practitioners seeking to stay current and for or... more

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Which podcasts are similar to NeurologyLive® Mind Moments®?

These podcasts share a similar audience with NeurologyLive® Mind Moments®:

1. Neurology® Podcast
2. Continuum Audio
3. Neurology Today in 5
4. NEI Podcast
5. Practical Neurology Podcast

How many episodes of NeurologyLive® Mind Moments® are there?

NeurologyLive® Mind Moments® launched 7 years ago and published 192 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on NeurologyLive® Mind Moments®?

Recent guests on NeurologyLive® Mind Moments® include:

1. Dr. Ontaneda
2. Grace Gombolay
3. Varun Kannan
4. Jessica Ailani
5. Todd Arnedt
6. Scott Grossman
7. Greg Pontone
8. Julie Kurek

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