Rephonic
Artwork for MDS Podcast
Parkinson's Disease
Movement Disorders
Deep Brain Stimulation
Dystonia
Essential Tremor
Clinical Trials
Neurology
Biomarkers
Progressive Supranuclear Palsy
Tremor
Alpha-Synuclein
Tourette Syndrome
International Parkinson and Movement Disorder Society
Artificial Intelligence
Neuroimaging
Machine Learning
Stigma
Multiple System Atrophy
Chorea
Cognitive Impairment

Stay up to date on novel, clinically-relevant research findings in Parkinson's disease and other movement disorders. Each episode of the International Parkinson and Movement Disorder Society podcast discusses a relevant development in the field, including highlighted journal articles and interviews with the authors.

PublishesWeeklyEpisodes304Founded7 years ago
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Science

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Artwork for MDS Podcast

Latest Episodes

Nicole Duff and Dr. Marjan Meinders discuss end of life preferences of people with Parkinson’s disease. Together they discuss the ways that end-of-life records could be sourced, as well as what information could be found in the end-of-life record. Th... more

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Dr. Connie Marras discusses with Dr. Sara Schaefer her recent study in Movement Disorders Clinical Practice exploring the perspective of Persons with Parkinson's disease on the definition of quality of life. Read the article.

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Myths and misconceptions related to the surgical risks of deep brain stimulation (DBS) procedures remain common despite many years of evidence demonstrating its relative safety. This leads to both patient and provider fear in referring eligible patie... more

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For many years ataxias, especially the genetic forms, were considered untreatable diseases. In this episode Dr. Orlando Barsottini and Dr. Liana Rosenthal discuss the new advances in the treatment of ataxias and perspectives for the future.

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Key Facts

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Find out how many people listen to this podcast per episode and each month.

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Recent Guests

Delaram Safarpour
Movement disorder neurologist and DBS specialist
Oregon Health & Science University
Episode: New data to reframe the risks of DBS surgery for patients and providers
Sheng Wu
Functional neurosurgeon
Thomas Jefferson University
Episode: New data to reframe the risks of DBS surgery for patients and providers
Liana Rosenthal
Associate Professor of Neurology and Director of the Taxa Center at Johns Hopkins University School of Medicine
Johns Hopkins University
Episode: Ataxia Series: Treating cerebellar ataxia in 2026 - What's new?
David Goldstein
Researcher from NIH focusing on autonomic failure and catecholamine deficiency in synucleinopathies
National Institutes of Health (NIH)
Episode: Prodromal autonomic dysfunction in Lewy body diseases
Abhimanyu Mahajan
Researcher focused on autonomic dysfunction as an early biomarker in neurodegenerative diseases
Episode: Prodromal autonomic dysfunction in Lewy body diseases
Alison Yarnall
Professor of Geriatric Medicine; expert on cognitive and non-motor features of Lewy body diseases
Newcastle University (implied from context)
Episode: Prodromal autonomic dysfunction in Lewy body diseases
Christofer Stephen
Assistant Professor of Neurology at Harvard Medical School; Neurology specialist discussing genetic ataxias
Mass General Hospital; Harvard Medical School
Episode: Ataxia Series: Beyond the cerebellum - Non-motor features and multisystem care in genetic ataxias
Rebecca Wallings
Researcher
Indiana University, Indianapolis
Episode: Modulating the peripheral immune response: LRRK2 and GBA1 mutations
Malco Rossi
Movement disorder neurologist
Plany Institution, Buenos Aires, Argentina
Episode: Ataxia Series: Neuroimaging patterns not to miss in ataxia

Hosts

Michele Matarazzo
Host of the MDS Podcast (leading host with focus on movement disorders and translational research)
Orlando Barsottini
Host of the MDS Podcast; neurology professional with ties to Brazilian institutions
Sara Schaefer
Host of the podcast episode

Reviews

4.8 out of 5 stars from 64 ratings
  • 雑音

    エピソードによって、プツプツプツと一定のリズムで雑音が混入しているものがある。

    Apple Podcasts
    2
    あちゃお19
    Japan7 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

High level, scholarly discussions with expert guests
Useful for researchers and clinicians seeking practical takeaways and future directions
Audio quality varies; some episodes include intermittent background noise

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#51
Chile/Science
Apple Podcasts
#109
China/Science
Apple Podcasts
#175
Colombia/Science
Apple Podcasts
#192
New Zealand/Science
Apple Podcasts
#210
Netherlands/Science
Apple Podcasts
#246
Argentina/Science

Talking Points

Recent interactions between the hosts and their guests.

New data to reframe the risks of DBS surgery for patients and providers
Q: What can be done to improve DBS referrals and patient comfort with the procedure?
Encourage earlier discussions about DBS, promote flexible multidisciplinary program models rather than a single rigid structure, and use communication strategies that normalize DBS as a viable option through education of both neurologists and general clinicians; emphasize that referral for evaluation does not commit a patient to surgery.
New data to reframe the risks of DBS surgery for patients and providers
Q: How would you counsel a patient who is evaluating DBS surgery given these new data?
Provide a balanced script that acknowledges the stigma of brain surgery, clearly communicates that DBS is not a cure but can meaningfully improve symptoms and quality of life, and uses relatable comparisons (e.g., risk levels similar to tonsillitis or hernia repair and much lower than hip/knee replacement) to set realistic expectations.
New data to reframe the risks of DBS surgery for patients and providers
Q: Where would you place DBS on the spectrum of surgical risk compared to other neurosurgical procedures?
DBS is generally less risky than many common elective neurosurgical procedures; when compared to a broad range, its overall complication rate is lower, and brain-specific complications are very rare, helping to frame DBS as a safer option in appropriate patients.
Ataxia Series: Treating cerebellar ataxia in 2026 - What's new?
Q: Yes. Have you mentioned recently Omaviloxalon was approved for Friedrich's ataxia? Could you tell us a little bit more about this drug? And my second question in this topic, is this drug indicated for all patients with Friedrich's ataxia, or we need some selection of patients?
Omaveloxalone is approved for individuals aged 16 and older, with ongoing studies in younger patients; it appears to provide symptom relief and potentially disease-modifying effects by stabilizing pathways affected in Friedrich's ataxia. Access for under-16 use is off-label or being studied, and safety concerns, especially liver function, must be carefully evaluated in younger patients and with insurance coverage considerations.
Modulating the peripheral immune response: LRRK2 and GBA1 mutations
Q: How did the LRRK2 mutations differ in their response compared with GBA1 mutations when treated with a Gcase activator?
LRRK2-mutant PBMCs showed a robust increase in MHC-II antigen presentation when treated with a Gcase activator, suggesting enhanced antigen processing and presentation, whereas GBA mutation carriers did not exhibit the same response, indicating different regulatory dynamics between these two genes.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
Professions
Age Range
Household Income
Social Media Reach

Frequently Asked Questions About MDS Podcast

What is MDS Podcast about and what kind of topics does it cover?

Across recent episodes, the show covers a broad span of movement disorders with a focus on Parkinson's disease, ataxias, dystonia, and related neurodegenerative conditions. Conversations often center on biomarkers, imaging, genetic etiologies, and clinical phenotypes, with an emphasis on translating research findings into practice, trial design, and multidisciplinary care. Noteworthy is the consistent involvement of clinicians and researchers from major institutions worldwide, plus a willingness to explore innovative methods (e.g., SCAN network theory, videography in phenotyping, immune pathways) that push beyond traditional motor symptom management. The format tends to pair clinical case discussions with expert interpretation, making it us... more

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Which podcasts are similar to MDS Podcast?

These podcasts share a similar audience with MDS Podcast:

1. Neurology® Podcast
2. Practical Neurology Podcast
3. Continuum Audio
4. The Michael J. Fox Foundation Parkinson's Podcast
5. Navigating Neuropsychology

How many episodes of MDS Podcast are there?

MDS Podcast launched 7 years ago and published 304 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on MDS Podcast?

Recent guests on MDS Podcast include:

1. Delaram Safarpour
2. Sheng Wu
3. Liana Rosenthal
4. David Goldstein
5. Abhimanyu Mahajan
6. Alison Yarnall
7. Christofer Stephen
8. Rebecca Wallings

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