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Artwork for MDS Podcast
Parkinson's Disease
Movement Disorders
Deep Brain Stimulation
Dystonia
Essential Tremor
Clinical Trials
Alpha-Synuclein
Neurology
Biomarkers
Progressive Supranuclear Palsy
Tremor
Tourette Syndrome
International Parkinson and Movement Disorder Society
Artificial Intelligence
Neuroimaging
Machine Learning
Stigma
Multiple System Atrophy
Chorea
Huntington's Disease

Stay up to date on novel, clinically-relevant research findings in Parkinson's disease and other movement disorders. Each episode of the International Parkinson and Movement Disorder Society podcast discusses a relevant development in the field, including highlighted journal articles and interviews with the authors.

PublishesWeeklyEpisodes311Founded7 years ago
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Science

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Artwork for MDS Podcast

Latest Episodes

In this episode, Dr. Mitra Afshari speaks with Dr. Jen Nagao about her latest work highlighting the automation of subthalamic deep brain stimulation (DBS) with Evoked Resonant Neural Activity (ERNA) in Parkinson’s disease. They discuss the potential ... more

Dr. Todd Gross and Dr. Laxman Bahroo discuss with Dr. Sara Schaefer the real-world use of daxibotulinumtoxinA in patients with cervical dystonia following initial clinical trials and FDA approval. Read the article.

YouTube

Dr. Asif Doja explores the diagnostic possibilities of behavioral arrests and loss of postural reflexes in a young boy, and details the diagnostic approach to such cases.

View the case videos:

KCNMA1-Related Episodes of Behavioral Arrest and Loss... more

YouTube

Ms. Nicole Duff spends time with Mrs. Cassandra Mulcahy and Prof. Stefan Mainka, both of whom are qualified music therapists. They discuss the benefits of music therapy in treating both motor and non-motor symptoms in persons with Parkinson's disease... more

YouTube

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Recent Guests

Lukshwong Bahroo
Professor of Neurology at Medstar Georgetown University Hospital
Georgetown University Hospital
Episode: DaxibotulinumtoxinA for cervical dystonia
Todd Gross
Vice President of Clinical Development and Data Science
Revance Therapeutics
Episode: DaxibotulinumtoxinA for cervical dystonia
Asif Doja
Associate Professor, pediatric neurologist
Children's Hospital of Eastern Ontario, Canada
Episode: What is it? Recurrent behavioral arrest and loss of postural reflexes
Cassandra Mulcahy
Music therapist with Berkeley and Temple credentials; based at Yale New Haven Health Bridgeport Hospital
Yale New Haven Health Bridgeport Hospital
Episode: Hot Topic: Music therapy in the rehabilitation of persons with Parkinson's disease
Stefan Mainka
Qualified music therapist; Deputy Head of the Master's program in Music Therapy
Parkinson Center, Berlin; University of the Arts Berlin
Episode: Hot Topic: Music therapy in the rehabilitation of persons with Parkinson's disease
Dr. Rajeev Kumar
Lead investigator and corresponding author of Movement Disorders Journal paper on Anx005 in Huntington's disease
Rocky Mountain Movement Disorder Center, Colorado, USA
Episode: Beyond the gene: Targeting neuroinflammation in Huntington's disease
Norihito Uemura
Researcher discussing the study
Kyoto University and Osaka Metropolitan University
Episode: Blocking alpha-synuclein propagation with perampanel
Marjan Meinders
Researcher
Radboud University Medical Center, Netherlands
Episode: End of life preferences of people with Parkinson's disease
Connie Marras
Professor of Neurology, University of Toronto; Movement Disorders Neurologist, University Health Network
University of Toronto; University Health Network
Episode: Quality of life in Parkinson’s disease

Hosts

Michele Matarazzo
Host of the MDS Podcast (leading host with focus on movement disorders and translational research)
Orlando Barsottini
Host of the MDS Podcast; neurology professional with ties to Brazilian institutions
Sara Schaefer
Host of the podcast episode

Reviews

4.8 out of 5 stars from 64 ratings
  • 雑音

    エピソードによって、プツプツプツと一定のリズムで雑音が混入しているものがある。

    Apple Podcasts
    2
    あちゃお19
    Japan7 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

High level, scholarly discussions with expert guests
Useful for researchers and clinicians seeking practical takeaways and future directions
Audio quality varies; some episodes include intermittent background noise

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#78
Ukraine/Science
Apple Podcasts
#145
South Korea/Science
Apple Podcasts
#204
New Zealand/Science
Apple Podcasts
#232
Ireland/Science

Talking Points

Recent interactions between the hosts and their guests.

DaxibotulinumtoxinA for cervical dystonia
Q: What practical tips would you give for treating a new patient, especially regarding dosing and retreatment intervals?
Start near the patient's prior toxin dose (e.g., Onabot) with careful titration, and set expectations for a median retreatment interval around 16 weeks, while recognizing individual variability and patient preferences for appointment timing.
DaxibotulinumtoxinA for cervical dystonia
Q: How is Daxify used outside the United States and what indications have been approved there?
Daxify has approvals beyond the US for dermatologic lines and other indications, including in Estonia (2023), China (2024), and Australia (2024), showing a broader regulatory acceptance beyond the initial US approvals.
DaxibotulinumtoxinA for cervical dystonia
Q: Can you briefly touch on the previous trials that led to FDA approval and what they showed?
Two phase 3 trials (Aspin-1 and Aspen-1) demonstrated efficacy with doses of 125 and 250 units and favorable safety profiles, followed by an open-label extension up to about a year where doses were titrated to about 300 units; together these trials supported FDA approval and established a 250-unit label, with real-world data suggesting higher titration may occur outside the controlled trial settings.
Hot Topic: Argentine tango in the rehabilitation of persons with Parkinson's disease
Q: Is the program replicable in other centers, and who can participate?
The program is designed to be scalable with trained instructors and volunteers; eligibility typically prioritizes certain disease stages, but there is flexibility to tailor based on safety and individual needs.
Hot Topic: Argentine tango in the rehabilitation of persons with Parkinson's disease
Q: How does tango function neurobiologically to aid movement in Parkinson's?
Dance and music activate dopaminergic pathways and engage external cues from rhythm and partner, which help bypass impaired internal cueing and promote neuroplastic changes.

Audience Metrics

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Frequently Asked Questions About MDS Podcast

What is MDS Podcast about and what kind of topics does it cover?

Across recent episodes, the show covers a broad span of movement disorders with a focus on Parkinson's disease, ataxias, dystonia, and related neurodegenerative conditions. Conversations often center on biomarkers, imaging, genetic etiologies, and clinical phenotypes, with an emphasis on translating research findings into practice, trial design, and multidisciplinary care. Noteworthy is the consistent involvement of clinicians and researchers from major institutions worldwide, plus a willingness to explore innovative methods (e.g., SCAN network theory, videography in phenotyping, immune pathways) that push beyond traditional motor symptom management. The format tends to pair clinical case discussions with expert interpretation, making it us... more

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Which podcasts are similar to MDS Podcast?

These podcasts share a similar audience with MDS Podcast:

1. Neurology® Podcast
2. Continuum Audio
3. Practical Neurology Podcast
4. JAMA Clinical Reviews
5. Neurology Minute

How many episodes of MDS Podcast are there?

MDS Podcast launched 7 years ago and published 311 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on MDS Podcast?

Recent guests on MDS Podcast include:

1. Lukshwong Bahroo
2. Todd Gross
3. Asif Doja
4. Cassandra Mulcahy
5. Stefan Mainka
6. Dr. Rajeev Kumar
7. Norihito Uemura
8. Marjan Meinders

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