Last Week in Medicine

Stephen Jenkins, MD, Austin Rupp, MD

Apixaban

Rivaroxaban

Bacteremia

Diabetes

Factor XI Inhibition

Semaglutide

Cystinosis

Pulmonary Embolism

Cardiovascular Disease

Hydrocortisone

Severe Pneumonia

Intensive Blood Pressure Control

Aldosterone Synthase Inhibitors

Hypertension

Reduced-Dose Apixaban

Cancer-Associated Thrombosis

Hematopoietic Stem Cell Gene Therapy

Acute Pulmonary Embolism

ACC/AHA Guidelines

COBRA Trial

Wouldn't it be nice if someone reviewed all the latest internal medicine literature and distilled it into a brief podcast you could listen to on your way to work? Get updates from the New England Journal of Medicine, JAMA Network, Annals of Internal Medicine, Journal of Hospital Medicine, Journal of General Internal Medicine, Lancet and more.

67 ratings

Publishes	Twice monthly	Episodes	67	Founded	6 years ago
Number of Listeners		Categories	Mental HealthHealth & FitnessMedicine

Listen to this Podcast

Guests Reviews Charts Talking Points

Latest Episodes

Catheter Directed Fibrinolysis for Acute PE (HI-PEITHO), NEWS2 Plus Procalcitonin Reduces Mortality (PRONTO)

Extra, extra, read all about it! We have two "NEWS" studies to talk about in this episode (bad pun). Does catheter directed thrombolysis improve outcomes in acute intermediate risk PE? Does adding procalcitonin to NEWS2 screening of ED patients real... more

7 Apr 2026 • 1 hr 1 min

Bleeding Risk with Apixaban vs Rivaroxaban for Acute VTE (COBRRA), Left Atrial Appendage Closure vs Medical Therapy for Atrial Fibrillation (CLOSURE-AF)

We are back with a landmark trial -- COBRRA was finally published! Apixaban wins again, but is rivaroxaban done for good??

Also, is left atrial appendage occlusion safer than oral anticoagulation in patients with a high risk of stroke and a high ri... more

28 Mar 2026 • 35 min

2026 ACC/AHA Guidelines for Acute Pulmonary Embolism

The ACC/AHA published new guidelines for managing acute PE on February 19, 2026. Today I'm joined by Dr. Scott Woller, MD, MACP, FCCP, who was co-chair of the American College of Chest Physicians Clinical Practice Guideline for antithrombotic therapy... more

11 Mar 2026 • 48 min

Hematopoietic Stem Cell Gene Therapy for Cystinosis

In this episode I'm joined by senior author Dr. Stephanie Cherqui to talk about her recent publication in the New England Journal of Medicine on gene therapy for cystinosis. This is a very personal episode for me, because two of my children have cyst... more

3 Mar 2026 • 41 min

Key Facts

Accepts Guests

Contact Information

Podcast Host

Number of Listeners

Find out how many people listen to this podcast per episode and each month.

Similar Podcasts

People also subscribe to these shows.

The Clinical Problem SolversThe Clinical Problem Solvers

The Curbsiders Internal Medicine PodcastThe Curbsiders Internal Medicine Podcast

Core IM | Internal Medicine PodcastCore IM Team

Critical Care TimeCritical Care Time Podcast

JAMA Clinical ReviewsJAMA Network

Recent Guests

Dr. Stephen Jenkins

Thrombologist guest on the show

Episode: Bleeding Risk with Apixaban vs Rivaroxaban for Acute VTE (COBRRA), Left Atrial Appendage Closure vs Medical Therapy for Atrial Fibrillation (CLOSURE-AF)

Scott Woller

Thrombosis expert, guest on the episode

Intermountain Health; University of Utah

Episode: 2026 ACC/AHA Guidelines for Acute Pulmonary Embolism

Stephanie Cherqui

Senior author of the NEJM study on cystinosis gene therapy

University of California, San Diego (UCSD)

Episode: Hematopoietic Stem Cell Gene Therapy for Cystinosis

Reviews

4.8 out of 5 stars from 67 ratings

Amazing
These guys help a lot of patients they’ll never meet. Best medicine podcast, hands down!
Apple Podcasts
5
ElleryAltshuler
United States3 years ago
Very informative and amusing!
I subscribed to RLR as I missed listening to the banter between Reza and Rabih - love the concise 30 minute cases with recap and the humor and camaraderie and humility that we can learn even from a med student and no one is or can “know-it-all”.
You guys are rock stars! Makes me feel enthusiastic and love Internal Medicine all over again - even after 30 years in the field - you infect your listeners with your passion to learn more and teach and diagnose! Keep the candle burning .. in this era wh... more
Apple Podcasts
5
Sharms04
United States3 years ago
Amazing
These guys help a lot of patients they’ll never meet. Best medicine podcast, hands down.
Apple Podcasts
5
ElleryAltshuler
United States3 years ago
An awesome way to stay up to date!
Thanks, guys for the great podcast- awesome way to stay caught up. They pick relevant, interesting articles and the conversation is always engaging!
Apple Podcasts
5
Pliu891
United States5 years ago
Fantastic
Wow- quality podcast! Entertaining, informative, and inspired. The perfect listen on my daily commute.
Apple Podcasts
5
Alexiarw
United States5 years ago

Embed These Reviews on a Website

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts	#34	Indonesia/Health & Fitness/Medicine
Apple Podcasts	#203	Indonesia/Health & Fitness
Apple Podcasts	#234	Singapore/Health & Fitness/Medicine

Talking Points

Recent interactions between the hosts and their guests.

2026 ACC/AHA Guidelines for Acute Pulmonary Embolism

Q: And that would be different than the 2021 recommendation in chest for minor reversible risk factors. What do you think about that?

The panel suggests a nuanced view where decisions depend on provoking events and persistent risk factors, recognizing a continuum of risk and highlighting a broader consideration for stopping versus continuing anticoagulation based on individual risk profiles.

2026 ACC/AHA Guidelines for Acute Pulmonary Embolism

Q: What do you think about that? Do you think every hospital needs a PERT?

There is strong guidance supporting the establishment of pulmonary embolism response teams, acknowledging non-randomized evidence, but the decision at each hospital is influenced by resources, costs, and local workflows; a regional tele-PERT could be a future solution to share expertise.

2026 ACC/AHA Guidelines for Acute Pulmonary Embolism

Q: So one question that I've had and maybe some of our listeners probably have is, do these guidelines supersede the last updates that we've had from other guideline bodies like chest, which the last one was in 2021, or are these complimentary guidelines?

The ACC/AHA approach represents an integrated, consensus-driven framework that collaborates with other guideline bodies, and while it may complement existing guidelines, it reflects a unified structure and representation from multiple societies to guide practice across categories and severities.

Hematopoietic Stem Cell Gene Therapy for Cystinosis

Q: What safety monitoring is used to ensure the vector does not cause harmful genomic changes?

Ongoing vector integration site analyses are performed every six months (then annually) to monitor for clonal expansion or insertional mutagenesis, ensuring the vector remains polymorphic and non-toxic over long-term follow-up.

Hematopoietic Stem Cell Gene Therapy for Cystinosis

Q: How does the treatment actually work once the patient receives the gene-modified stem cells?

Patients undergo collection of hematopoietic stem cells, which are then modified with a lentiviral vector carrying the corrected gene, and after conditioning with busulfan, receive an infusion of these edited cells that engraft and produce cell lineages capable of delivering the therapeutic protein across tissues.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

Listeners per Episode
Gender Skew
Location
Interests
Professions
Age Range
Household Income
Social Media Reach

Frequently Asked Questions About Last Week in Medicine

Where can I find podcast stats for Last Week in Medicine?

Rephonic provides a wide range of podcast stats for Last Week in Medicine. We scanned the web and collated all of the information that we could find in our comprehensive podcast database. See how many people listen to Last Week in Medicine and access YouTube viewership numbers, download stats, audience demographics, chart rankings, ratings, reviews and more.

How many listeners does Last Week in Medicine get?

Rephonic provides a full set of podcast information for three million podcasts, including the number of listeners. View further listenership figures for Last Week in Medicine, including podcast download numbers and subscriber numbers, so you can make better decisions about which podcasts to sponsor or be a guest on. You will need to upgrade your account to access this premium data.

What are the audience demographics for Last Week in Medicine?

Rephonic provides comprehensive predictive audience data for Last Week in Medicine, including gender skew, age, country, political leaning, income, professions, education level, and interests. You can access these listener demographics by upgrading your account.

How many subscribers and views does Last Week in Medicine have?

To see how many followers or subscribers Last Week in Medicine has on Spotify and other platforms such as Castbox and Podcast Addict, simply upgrade your account. You'll also find viewership figures for their YouTube channel if they have one.

Which podcasts are similar to Last Week in Medicine?

These podcasts share a similar audience with Last Week in Medicine:

1. The Clinical Problem Solvers
2. The Curbsiders Internal Medicine Podcast
3. Core IM | Internal Medicine Podcast
4. Critical Care Time
5. JAMA Clinical Reviews

How many episodes of Last Week in Medicine are there?

Last Week in Medicine launched 6 years ago and published 67 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact Last Week in Medicine?

Our systems regularly scour the web to find email addresses and social media links for this podcast. We scanned the web and collated all of the contact information that we could find in our podcast database. But in the unlikely event that you can't find what you're looking for, our concierge service lets you request our research team to source better contacts for you.

Where can I see ratings and reviews for Last Week in Medicine?

Rephonic pulls ratings and reviews for Last Week in Medicine from multiple sources, including Spotify, Apple Podcasts, Castbox, and Podcast Addict.

View all the reviews in one place instead of visiting each platform individually and use this information to decide if a show is worth pitching or not.

How do I access podcast episode transcripts for Last Week in Medicine?

Rephonic provides full transcripts for episodes of Last Week in Medicine. Search within each transcript for your keywords, whether they be topics, brands or people, and figure out if it's worth pitching as a guest or sponsor. You can even set-up alerts to get notified when your keywords are mentioned.

What guests have appeared on Last Week in Medicine?

Recent guests on Last Week in Medicine include:

1. Dr. Stephen Jenkins
2. Scott Woller
3. Stephanie Cherqui

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

Find and pitch the right podcasts

We help savvy brands, marketers and PR professionals to find the right podcasts for any topic or niche. Get the data and contacts you need to pitch podcasts at scale and turn listeners into customers.

Try it free for 7 days