Harrison's PodClass: Internal Medicine Cases and Board Prep

AccessMedicine

Hypertension

Harrison's Principles Of Internal Medicine

Obesity

Cardiovascular Disease

Pregnancy

Altitude Illness

Pulmonary Edema

Stroke

Prostate Cancer

Heart Failure

Metabolic Syndrome

Acute Mountain Sickness

Diabetes

Obstructive Sleep Apnea

Chronic Kidney Disease

Pulmonary Hypertension

Acute Respiratory Distress Syndrome

Cirrhosis

Cardiac Transplantation

Johns Hopkins School Of Medicine

Produced by McGraw Hill, Harrison's Podclass delivers illuminating and engaging discussions led by Drs. Cathy Handy Marshall and Charlie Wiener of The John Hopkins School of Medicine on key topics in medicine, featuring board-style case vignettes from Harrison's Review Questions and chapters from the acclaimed Harrison's Principles of Internal Medicine – available on AccessMedicine from McGraw Hil... more

1.5k ratings

Publishes	Weekly	Episodes	198	Founded	7 years ago
Number of Listeners		Categories	Health & FitnessEducationMedicine

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Latest Episodes

Ep 199: A 75-Year-Old With Neuropathic-Type Pain and Weakness

This episode reviews causes and consequences of macrocytic anemia.

Ep 198: A 54-Year-Old with Aortic Stenosis

This episode reviews the diagnosis and complications of aortic stenosis.

Ep 197: A 77-Year-Old Hospitalized with Pneumonia

This episode reviews the diagnostic workup of patients with confusion while hospitalized for pneumonia.

Ep 196: A 48-Year-Old with Worsening Headaches

This episode reviews the diagnostic workup for causes of headache.

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Accepts Sponsors

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Recent Guests

Katarina Heidhausen

Executive Editor of Harrison's Principles of Internal Medicine

Harrison's/Harrison's Principles of Internal Medicine, McGraw Hill

Episode: Ep 192: A 44-Year-Old Concerned about MEN Syndromes

Dr. Andrew Josephson

Chair of Neurology

University of California at San Francisco

Episode: Ep 169: A 65-Year-Old with Right-Sided Weakness

Hosts

Cathy Handy

Co-host of Harrison's PodClass; Johns Hopkins School of Medicine clinician

Charlie Wiener

Co-host of Harrison's PodClass; Johns Hopkins School of Medicine clinician

Reviews

4.9 out of 5 stars from 1.5k ratings

nice one amazing
Podchaser
5
dr.waleed1981
25 days ago
Great cases
Excellent work. I try not to miss any cases.
Apple Podcasts
5
docfred7601
United States3 months ago
Good information
The hosts are very monotone, the content is very useful.
Apple Podcasts
4
Antic2026
United States4 months ago
Simply perfect!
Please never stop with this podcast. Its incredibly high-quality cases are mixed with the perfect amount of notions to learn and revise quickly and in an enjoyable way. Awesome work!
Apple Podcasts
5
AlexioCR
Italy6 months ago
Succinct vignettes
I am an internist preparing to do LKA. Stumbled upon this podcast by accident. I just listened to the episode on heart failure and it was a great review of the pathology of heart failure. I hope there will be accompanying CME and MOC points for this.
Apple Podcasts
5
Dr SayaPam
United States7 months ago

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Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Great for board prep and quick review; highly shareable insights.

Concise, high-yield medical education that fits a busy schedule.

Candid, practical case discussions that reinforce clinical reasoning.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts	#44	United States/Health & Fitness/Medicine
Apple Podcasts	#76	Canada/Health & Fitness/Medicine
Apple Podcasts	#163	United Kingdom/Health & Fitness/Medicine
Apple Podcasts	#49	Australia/Health & Fitness/Medicine
Apple Podcasts	#135	Italy/Health & Fitness/Medicine
Apple Podcasts	#231	India/Top Podcasts

Talking Points

Recent interactions between the hosts and their guests.

Ep 197: A 77-Year-Old Hospitalized with Pneumonia

Q: The question asks, in this patient, which of the following is the most specific diagnostic test?

The most specific diagnostic approach is clinical examination at the bedside, supported by CAM as a diagnostic aid.

Ep 196: A 48-Year-Old with Worsening Headaches

Q: Can tacrolimus cause PRESS even if drug levels are normal, and why does this matter clinically?

Yes, calcineurin inhibitors can contribute to PRESS even at normal levels, so clinicians should consider drug-induced endothelial effects in the differential when post-transplant patients present with acute neurologic symptoms.

Ep 196: A 48-Year-Old with Worsening Headaches

Q: What are the main pathophysiological mechanisms behind PRESS in transplant patients on calcineurin inhibitors?

PRESS arises from a combination of endothelial dysfunction leading to breakdown of the blood-brain barrier and cerebral autoregulatory failure, causing regional hyperperfusion and vasogenic edema, especially in the posterior circulation.

Ep 196: A 48-Year-Old with Worsening Headaches

Q: What is the imaging modality of choice for diagnosing PRESS in this patient?

MRI of the head is the most diagnostic, showing characteristic posterior-predominant vasogenic edema, whereas CT may be less sensitive and non-diagnostic.

Ep 195: A 43-Year-Old with Chest Pain

Q: Not yet. First, your question. The question asks, in this patient, which of the following is most likely?

Based on the history and exam, I think this patient has post-viral acute pericarditis, though we must remain cautious about acute MI given his risk factors and family history.

Audience Metrics

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Frequently Asked Questions About This Podcast

What is This Podcast about and what kind of topics does it cover?

This show delivers board-style, case-based discussions on internal medicine topics, using brief, focused vignettes to reinforce clinical reasoning and diagnostic strategies. Episodes frequently spotlight practical pearls across common and complex conditions (cardiology, endocrinology, nephrology, infectious disease, geriatrics, and more), with structured reasoning that helps busy clinicians apply concepts at the bedside. A distinctive feature is the tight, high-yield format designed for quick study, often with references to Harrison's resources and AccessMedicine sponsorships, making it useful for exam prep, CME-type review, and daily clinical practice. The cadence is concise and teachable, appealing to trainees and practicing physicians se... more

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These podcasts share a similar audience with this podcast:

1. Core IM | Internal Medicine Podcast
2. Annals On Call Podcast
3. JAMA Clinical Reviews
4. The Clinical Problem Solvers
5. The Curious Clinicians

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this podcast launched 7 years ago and published 198 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on this podcast?

Recent guests on this podcast include:

1. Katarina Heidhausen
2. Dr. Andrew Josephson

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