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Newborn Screening
Gene Therapy
Inborn Errors Of Metabolism
Urea Cycle Disorders
Inherited Metabolic Diseases
Clinical Trials
Inherited Metabolic Disease
Metabolic Disorders
Phenylketonuria
Enzyme Replacement Therapy
Mitochondrial Disorders
Pregnancy
Lysosomal Storage Disorders
Galactosemia
Genetic Testing
PKU
Methylmalonic Aciduria
Classic Galactosemia
NAXD Deficiency
Adult Metabolic Centers

JIMD Podcasts is home to the Journal of Inherited Metabolic Disease podcast and the JIMD Shortcast. We're also proud to showcase Metabolic Mysteries and the new Footprints in IMD podcast.

PublishesWeeklyEpisodes287Founded6 years ago
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Artwork for JIMD Podcasts

Latest Episodes

A young girl develops progressive neurological symptoms and a biomarker profile pointing strongly towards a particular metabolic disorder. There’s just one problem: the genetic testing is negative. In this Metabolic Mystery, Dr Ayca Burcu Kahraman fo... more

A 7-year-old boy presents following a suspected seizure, with a history of progressive ataxia and tremor. An MRI offers an important clue but a seemingly reassuring blood result complicates the picture. In this Metabolic Mystery, Dr Steven Lang follo... more

Cytopenias and infections are familiar complications of branched-chain organic acidemias, but are they simply consequences of metabolic decompensation? Abdul Shakerdi and Jerry Vockley join the JIMD Podcast to explore evidence that persistent immune ... more

In this JIMD Reports Shortcast, Dr Eamon McCarron presents a challenging pregnancy in a woman with lysinuric protein intolerance complicated by immune dysregulation and severe thrombocytopenia. Hear how multidisciplinary management supported a favour... more

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Recent Guests

Abdul Shakerdi
First author of the paper discussed
Episode: Beyond Metabolic Control: Immune Dysregulation in Organic Acidemias
Jerry Vockley
Senior author of the paper discussed
Episode: Beyond Metabolic Control: Immune Dysregulation in Organic Acidemias
Elifişler Soylu
Speaker from Istanbul, Turkey introducing research at the conference
Ssiem attendee from Istanbul
Episode: Helsinki: Day 4 - New friends, fond farewells, and Dublin calling
Caroline Grothardt
Speaker on prokaryotic catabolism and therapeutic targets
Episode: Helsinki: Day 4 - New friends, fond farewells, and Dublin calling
Dumailo Satecha
Representative from South Africa presenting a case report on prokaryotic nega-cidemia
South Africa clinical researcher
Episode: Helsinki: Day 4 - New friends, fond farewells, and Dublin calling
Miriam Gürda
PhD student researching mitochondrial energy production in MMA
University of Zurich Hospital
Episode: Helsinki: Day 4 - New friends, fond farewells, and Dublin calling
Greg Woodhead
Metabolic physician presenting GLP-1 therapy in urea cycle disorder poster
Sydney Children's Hospital Network
Episode: Helsinki: Day 4 - New friends, fond farewells, and Dublin calling
Oliver Heath
PhD candidate discussing reverse phenotyping after exome sequencing
Salzburg, Austria
Episode: Helsinki: Day 4 - New friends, fond farewells, and Dublin calling
Tim Fazio
Metabolic physician presenting hyperammonemia after bariatric surgery poster
Melbourne, Australia
Episode: Helsinki: Day 4 - New friends, fond farewells, and Dublin calling

Hosts

Sylvia Rodenkovich
Host with ties to Laboratory Genetics and related metabolic disorder programs.
James Nurse
Host of the JIMD Podcast with a focus on metabolic disorders.

Reviews

4.9 out of 5 stars from 49 ratings
  • Thank you!

    I’m a dietitian new to metabolism in the last 1.5 years and this podcast has been very helpful! Thank you!

    Apple Podcasts
    5
    Mandy Benedict
    United States8 months ago
  • Great podcast!

    As a metabolic fellow I love listening to the podcast! Super informative

    Apple Podcasts
    5
    MaxwellPodcast
    United Statesa year ago
  • Informative interviews

    Great interviews with the authors of recent JIMD articles. Neat way to gain insights quickly

    Apple Podcasts
    5
    MichelTchan
    Australia6 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Great interviews with clinicians and researchers that stay tightly focused on practical IMD topics.
Listeners note the depth of biomarker and treatment discourse.
Guests are typically leading researchers; format is data- and case-driven.
Audience appreciates concise, expert-driven discussions with translational relevance to patient care.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#13
Ukraine/Science
Apple Podcasts
#95
Argentina/Science

Talking Points

Recent interactions between the hosts and their guests.

Beyond Metabolic Control: Immune Dysregulation in Organic Acidemias
Q: Can I ask that we start with the origins of this review? What prompted you to look specifically at immune dysregulation in organic acidemias?
Abdul and I noticed clinical observations of inflammatory signals in patients with organic acidemias, even beyond crises, which led us to investigate whether there could be a metabolic basis for immune dysregulation and whether the relationship runs in both directions.
Feeding the Microbiome: Rethinking Protein and Propionate in MMA
Q: What should clinicians take away from these findings in terms of balancing metabolic benefit against microbiome disruption?
Carefully optimized intact protein intake may improve metabolic balance while reducing dependence on leucine-heavy formulas, but intermittent metronidazole can alter microbiome diversity and gut health, suggesting a need for individualized, microbiome-informed therapy.
Feeding the Microbiome: Rethinking Protein and Propionate in MMA
Q: What was the key clinical question behind this study?
The researchers aimed to determine whether metabolic stability in MMA could be improved by optimizing both the amount and type of protein, and by considering the interactions with the gut microbiome.
High Glycine, Different Diagnoses
Q: So thanks both for joining me and overcoming the time zone challenges. Can I ask that we begin with the basics?
We discuss how glycine sits at the center of a complex differential, the shift away from simple labels like NKH to a broader glycine encephalopathy framework, and how history informs current clinical practice.
IMD Research Round-Up: Homocystinuria
Q: Why is newborn screening for homocystinuria important beyond technical details?
Newborn screening is crucial because early diagnosis allows diet-based interventions to prevent major complications, with ongoing trials aiming to relax dietary restrictions while maintaining safety.

Audience Metrics

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Frequently Asked Questions About JIMD Podcasts

What is JIMD Podcasts about and what kind of topics does it cover?

This show centers on inherited metabolic diseases, with a strong emphasis on diagnostics, newborn screening, treatment advances, and practical management across rare conditions like PKU, SLOS, CTX, homocystinuria, and DBP deficiency. Episodes blend clinical case discussions, research roundups, and policy or screening debates, often featuring leading researchers and clinicians who share biomarker updates, genotype–phenotype insights, and emerging therapies. Noteworthy elements include a consistent focus on real-world patient impact, cross-institution collaboration, and the exploration of precision medicine approaches in rare metabolic disorders. Listeners are likely clinicians, researchers, and program managers seeking concise, expert perspe... more

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Which podcasts are similar to JIMD Podcasts?

These podcasts share a similar audience with JIMD Podcasts:

1. Neurology® Podcast
2. You're Dead to Me
3. Parenting Hell with Rob Beckett and Josh Widdicombe
4. Science Vs
5. The Louis Theroux Podcast

How many episodes of JIMD Podcasts are there?

JIMD Podcasts launched 6 years ago and published 287 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on JIMD Podcasts?

Recent guests on JIMD Podcasts include:

1. Abdul Shakerdi
2. Jerry Vockley
3. Elifişler Soylu
4. Caroline Grothardt
5. Dumailo Satecha
6. Miriam Gürda
7. Greg Woodhead
8. Oliver Heath

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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