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Endocrine Feedback Loop

Endocrine Society
Obesity
Type 2 Diabetes
Bariatric Surgery
Glucocorticoids
Osteoporosis
Semaglutide
Polycystic Ovary Syndrome
Anti-Obesity Medications
Calcium Levels
Primary Hyperparathyroidism
Metformin
Chronic Kidney Disease
Type 1 Diabetes
Polycystic Ovarian Syndrome
Thyroid Cancer
HPA Axis
Adrenal Insufficiency
Weight Management
Endocrinology
Tertiary Adrenal Insufficiency

Endocrine Feedback Loop is a monthly journal club podcast series brought to you by the Endocrine Society. Hosted by endocrinologist Chase Hendrickson, MD, from Vanderbilt University, each episode features an expert educator and a topical specialist dissecting recently published journal articles and discussing implications for clinical practice.

PublishesMonthlyEpisodes79Founded3 years ago
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MedicineHealth & Fitness

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Artwork for Endocrine Feedback Loop

Latest Episodes

For our 78th episode, we review a recent Journal of the Endocrine Society (JES) article reporting results from a Phase 2, single-dose trial of an SGLT1 inhibitor for post-bariatric hypoglycemia. This condition can be particularly difficult to diagnos... more

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For our 77th episode, we discuss a study in the Journal of Clinical Endocrinology & Metabolism investigating the role of immune signaling in polycystic ovary syndrome (PCOS), now renamed polyendocrine metabolic ovarian syndrome (PMOS). Using a multir... more

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For our 76th episode, we discuss a recent Journal of Clinical Endocrinology & Metabolism secondary analysis examining pregnancy outcomes among women with polycystic ovary syndrome (PCOS) and gestational diabetes mellitus (GDM). Drawing on data from t... more

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How does the severity of Graves disease at presentation affect subsequent methimazole dose titration? Find out more in this month's episode!

For our 75th episode, we review a forthcoming Journal of Clinical Endocrinology & Metabolism study examining... more

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Recent Guests

Sangeeta Kashyap
Assistant Chief of Clinical Affairs in endocrinology, diabetes and metabolism
Weill Cornell Health
Episode: EFL078 - SGLT1 Inhibition for the Treatment of Post-Bariatric Hypoglycemia
Corrine Welt
Division Chief of Endocrinology, University of Utah
University of Utah
Episode: EFL077 - Inflammation vs. Immune-System Dysfunction in PCOS
Ellen Seely
Guest expert; directs clinical research in endocrinology, diabetes and hypertension
Brigham and Women's Hospital, Harvard Medical School
Episode: EFL076 - Pregnancy Outcomes in PCOS and GDM
Jonea Lim
General Endocrinologist and Fellowship Program Director
University of Oklahoma
Episode: EFL075 - Methimazole Titration and Initial Disease Severity in Graves' Disease
Elizabeth Pearce
Fellowship Program Director focusing on thyroid disease
Boston University
Episode: EFL075 - Methimazole Titration and Initial Disease Severity in Graves' Disease
Andy Crawford
Endocrinologist, Dartmouth-Hitchcock Medical Center
Dartmouth-Hitchcock Medical Center
Episode: EFL074 - Taking Levothyroxine Fasting vs. With Breakfast
Matt Edelson
Endocrinologist with epidemiology and health services research focus
University of Chicago
Episode: EFL074 - Taking Levothyroxine Fasting vs. With Breakfast
Tom Weber
Guest expert in bone health
Duke Health
Episode: EFL073 - Infrequent Zoledronate in Low Fracture Risk
Salila Kurra
Adrenal center co-director and clinical chief of endocrinology at Columbia University
Columbia University, New York City
Episode: EFL072 - Pre-Operative Use of Mineralocorticoid-Receptor Antagonists in Primary Aldosteronism

Host

Chase Hendrickson
Host of Endocrine Feedback Loop and affiliated with Vanderbilt Health/Vanderbilt University Medical Center (varying listings across episodes)

Reviews

5.0 out of 5 stars from 30 ratings
  • The best endocrine podcast

    I wait every week for EFL.

    It’s the best podcast I’ve ever recommend!

    Strongly recommend!

    Apple Podcasts
    5
    PK09866
    Poland3 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

International perspectives often broaden the clinical context.
High-quality clinical discussions with strong guest expertise.
Readers gain practical takeaways for managing complex endocrine conditions.
Guests are typically noted experts, adding credibility to the conversations.
Episodes balance study design critique with real-world application.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

EFL078 - SGLT1 Inhibition for the Treatment of Post-Bariatric Hypoglycemia
Q: Do you think that this fully explains the process here, this idea of the reduced intestinal glucose absorption, and then that's leading to reduced postprandial GIP? Are there other things that we need to be thinking about?
Kashyap considers reduced glucose absorption the likely mechanism and GIP reduction a marker rather than a mediator. Flattening the post-meal glucose rise may also reduce GLP signaling and the exaggerated insulin response.
EFL078 - SGLT1 Inhibition for the Treatment of Post-Bariatric Hypoglycemia
Q: Does there a role of bile acids in this phenomena?
Kashyap says bile acids may contribute through improved insulin sensitivity after gastric bypass, alongside changes in insulin signaling, ectopic fat, nutrient delivery and intestinal glucose absorption.
EFL075 - Methimazole Titration and Initial Disease Severity in Graves' Disease
Q: Does initial disease severity influence the time to euthyroidism when using methimazole titration?
The study suggests that while initial severity affects early dosing intensity and monitoring frequency, it does not significantly change the overall time to euthyroidism, as all groups converge to euthyroid status within similar time frames.
EFL073 - Infrequent Zoledronate in Low Fracture Risk
Q: What is the main takeaway about dosing intervals for zoledronic acid in this low-risk population?
The study suggests that infrequent dosing (every five years or ten years) can reduce fracture risk in low-risk women, particularly between years 5 and 10, but applicability to everyday practice is cautious due to the low-risk cohort and need to balance harms and benefits.
EFL071 – Taste Changes with Semaglutide
Q: How do the authors interpret the relationship between weight loss and taste/brain changes?
They acknowledge it could be a direct pharmacologic effect or an indirect effect mediated by weight loss, noting that causality cannot be distinguished within this study and that further weight-matched designs are needed.

Audience Metrics

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Frequently Asked Questions About Endocrine Feedback Loop

What is Endocrine Feedback Loop about and what kind of topics does it cover?

This monthly journal-club style show pulls together practicing endocrinologists and subject-matter experts to dissect recently published papers and translate findings into clinical practice. Episodes consistently center on thyroid, osteoporosis, diabetes, obesity, and adrenal disorders, with careful consideration of study design, limitations, and real-world applicability. A notable strength is the rigorous, multi-guest format that blends clinical insight with research context, often featuring international perspectives and first-author commentary. Listeners can expect practical implications, nuanced discussions of dosing, monitoring, and patient management, and a strong emphasis on translating trials into everyday endocrinology practice.

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Which podcasts are similar to Endocrine Feedback Loop?

These podcasts share a similar audience with Endocrine Feedback Loop:

1. Endocrine News Podcast
2. AACE Podcasts
3. The Curbsiders Internal Medicine Podcast
4. JAMA Clinical Reviews
5. Mayo Clinic Talks

How many episodes of Endocrine Feedback Loop are there?

Endocrine Feedback Loop launched 3 years ago and published 79 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Endocrine Feedback Loop?

Recent guests on Endocrine Feedback Loop include:

1. Sangeeta Kashyap
2. Corrine Welt
3. Ellen Seely
4. Jonea Lim
5. Elizabeth Pearce
6. Andy Crawford
7. Matt Edelson
8. Tom Weber

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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