Rephonic
Artwork for Dementia Matters
Alzheimer's Disease
Dementia
Mild Cognitive Impairment
Cognitive Decline
Tau Protein
Cognitive Impairment
Clinical Trials
Wisconsin Alzheimer's Disease Research Center
Caregiving
Nutrition
Mental Health
Neurodegenerative Diseases
Brain Health
Ultra-Processed Foods
Amyloid
Physical Activity
Early Detection
Frontotemporal Dementia
Public Health
Lewy Body Dementia

Dementia Matters is a podcast about Alzheimer‘s disease and other causes of dementia. Creator and host Dr. Nathaniel Chin interviews leading scientists and caregiving experts to bring listeners the latest in Alzheimer’s disease news, research and caregiver resources. Brought to you by the Wisconsin Alzheimer’s Disease Research Center, find show notes and more resources at dementiamatters.adrc.wisc... more

PublishesTwice monthlyEpisodes244Founded9 years ago
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MedicineHealth & FitnessScience

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Artwork for Dementia Matters

Latest Episodes

In recent years, public interest in brain health has increased. So how are Americans understanding brain health information and incorporating it into their own lives? This year, the Alzheimer’s Association released a special report focused on how peo... more

Twenty-five years ago, a single participant enrolled in what would become the Wisconsin Registry for Alzheimer's Prevention (WRAP), now one of the largest and longest-running studies of Alzheimer's risk in the world. To celebrate this milestone, we’r... more

YouTube

Caring for those with dementia represents a major public health challenge, with caregivers, especially spouses, providing long-term, largely unpaid care. With caregiving stress linked to a decline in mental and physical health, it is crucial to under... more

YouTube

Prescription medications, over-the-counter drugs and supplements are incredibly common among older adults, yet many of these routine treatments can unexpectedly impact cognitive function and brain health. To help us safely navigate medication managem... more

YouTube

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Recent Guests

Mark Sager
Founder of the Wisconsin Alzheimer's Institute and co-founder of RAP
Wisconsin Alzheimer's Institute; RAP
Episode: Reflecting on 25 Years of the Wisconsin Registry for Alzheimer’s Prevention
Sterling Johnson
Lead Principal Investigator of RAP; former RAP PI
Wisconsin Alzheimer's Disease Research Center; Wisconsin Alzheimer's Institute
Episode: Reflecting on 25 Years of the Wisconsin Registry for Alzheimer’s Prevention
Jessica Caldwell
Board-certified neuropsychologist; new multi-principal investigator of RAP; visiting associate professor
UW–Madison Department of Neurology
Episode: Reflecting on 25 Years of the Wisconsin Registry for Alzheimer’s Prevention
Donna de Levante Raphael
Director of Research at the Alzheimer's Foundation of America, researcher focusing on caregiver burden and health outcomes
Alzheimer's Foundation of America
Episode: How Dementia Caregiving Affects the Spousal Caregiver
Lauren Welch
Clinical Geriatric Pharmacy Practitioner, VA Geriatrics Research Education and Clinical Center
Veterans Affairs; Memory Clinic
Episode: Managing the Medicine Cabinet: How Prescriptions Impact Cognition and Brain Health as We Age
Dr. Frank Jessen
Professor of Psychiatry and Psychotherapy; director of the Department of Psychiatry at the University of Cologne
University of Cologne; DZNE; European Alzheimer's Disease Consortium
Episode: Defining Subjective Cognitive Decline
Mark Supiano
Gerontologist and researcher focusing on blood pressure control in older adults
University of Utah
Episode: SPRINT to a Healthy Mind: How Blood Pressure Control Affects Brain Health and Dementia Risk
Simon Asher
Researcher involved in net clinical benefit analyses for hypertension
Academic collaborator
Episode: SPRINT to a Healthy Mind: How Blood Pressure Control Affects Brain Health and Dementia Risk
Henrik Zetterberg
Biomarker and disease biology expert
Episode: Addressing Cochrane’s Review on Amyloid-Targeting Treatments for Alzheimer’s Disease

Host

Dr. Nathaniel Chin
Host of dementia-focused discussions and researcher affiliated with the Wisconsin Alzheimer's Disease Research Center.

Reviews

4.6 out of 5 stars from 207 ratings
  • Excellent source of detailed information for layperson dealing with dementia in real life.

    Podcast Addict
    5
    Theo_Williamson
    2 months ago
  • Science based but accessible

    As a caregiver, I’ve learned so much from every guest - the scientists explaining cutting edge research, the caregivers sharing best practices (mindfulness!), and the people with neurodegenerative diseases sharing what it’s like from the inside. Thank you, UW! May God (and govt) preserve your funding!!!

    Apple Podcasts
    5
    albany mama
    United Statesa year ago
  • Thanks

    I’ve learned so much from your podcast. Thank you for it and for all the work you do. I miss UW Madison! Thanks for passing some of it on to me.

    Apple Podcasts
    5
    Wholeness seeker
    United States2 years ago
  • Best for beginners who want only superficial information

    If you appreciate deep-dive conversations in the vein of Peter Attia’s “The Drive” podcast, this one is _not_ for you. Even on topics with a seemingly limitless amount of interesting scientific information to explore, e.g. “APOE4”, the content seems to be aimed at an audience who would be disturbed or confused by an objective examination of statistics, relative risk, genetics, etc., and also uninterested in science itself as an intellectual pursuit. Also, many episodes are heavy on ideological s... more

    Apple Podcasts
    1
    HideFromHider
    United States2 years ago
  • Great podcast on fundamentals of testing and diagnosis

    Dr Williams broke down so many definitions and concepts in dementia care! Great job. Unfortunately, there are not enough available neuropsychologists to evaluate everyone with memory concerns. Screening tests, with a careful history, has a role in the diagnosis of dementia, as I saw in the non-academic memory center I worked in.

    Apple Podcasts
    5
    BarbAnn
    United States2 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Praise for practical caregiving guidance and expert interviews.
Listeners value the evidence-based yet accessible clinical insights.
Some critics want deeper technical analysis and statistics.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Reflecting on 25 Years of the Wisconsin Registry for Alzheimer’s Prevention
Q: What were the gaps RAP aimed to fill when it started in 2001, and how did the field look then?
At the outset, biomarkers were absent, imaging was limited, and there was a focus on symptomatic disease; RAP aimed to map the preclinical phase, integrate biomarkers, and study risk factors in a younger cohort to understand disease trajectories.
Reflecting on 25 Years of the Wisconsin Registry for Alzheimer’s Prevention
Q: My first question is, how did the RAP study actually get started?
The RAP study began as a collaboration between Mark Sager and Bruce Herman, leveraging a small initial grant and the idea of studying people at risk rather than those with established disease, with early recruitment challenges offset by perseverance and a compelling rationale.
Taking a Deep Dive into Subjective Cognitive Decline
Q: If you could choose any biomarkers to understand SCD, what would you pick?
Amyloid PET to confirm amyloid presence, tau PET to assess extension of tau, and FDG-PET for hypometabolism patterns; blood-based measures like Aβ42/40 and p-Tau217 are also discussed as promising early signals.
Taking a Deep Dive into Subjective Cognitive Decline
Q: What is the overlap of SCD with Alzheimer's disease?
SCD is considered an early, first symptomatic stage in the Alzheimer's trajectory, where there is subjective experience of decline and compensation by the brain, preceding objective dysfunction; not all SCD is due to Alzheimer's, but a substantial subset shows amyloid positivity and risk of progression.
Defining Subjective Cognitive Decline
Q: What are the current treatment options for someone with SCD?
There are no approved pharmacological treatments for SCD yet; management focuses on addressing reversible factors, cognitive training, physical activity, and cardiovascular risk reduction, with biomarker use evolving over time.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About Dementia Matters

What is Dementia Matters about and what kind of topics does it cover?

This show consistently covers dementia—from patient care to prevention, diagnosis, and trial design—through conversations with clinicians, researchers, and care professionals. Topics frequently center on caregiver burdens, precision and equity in caregiver support, polypharmacy and cognition in aging, and multi-domain lifestyle approaches to brain health. Guests range from pharmacology and nutrition experts to memory-clinic social workers and driving-ability researchers, often tying clinical findings to practical guidance for families, clinicians, and policy. A notable strength is translating complex science into actionable insights, with regular attention to accessibility, real-world implementation, and community implications for rural and... more

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Which podcasts are similar to Dementia Matters?

These podcasts share a similar audience with Dementia Matters:

1. GeriPal - A Geriatrics and Palliative Medicine Podcast
2. The People's Pharmacy
3. PLANTSTRONG Podcast
4. Nutrition Diva
5. Heart Doc VIP with Dr. Joel Kahn

How many episodes of Dementia Matters are there?

Dementia Matters launched 9 years ago and published 244 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Dementia Matters?

Recent guests on Dementia Matters include:

1. Mark Sager
2. Sterling Johnson
3. Jessica Caldwell
4. Donna de Levante Raphael
5. Lauren Welch
6. Dr. Frank Jessen
7. Mark Supiano
8. Simon Asher

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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