Rephonic
Artwork for Weekly Pep Talk
Retatrutide
Peptides
Tesamorelin
Bpc-157
Blood Work / Blood Panels
Bacteriostatic Water Shortage
Kisspeptin
TRT (testosterone Replacement Therapy)
PNC 27
Fasting
Red Etrutide
Summer Shred Stack
Certificate Of Analysis (COA)
P22-28
Over-the-Counter Peptide Sourcing
Tb-500
Tirzepatide
HCG
PNC 28
Red Atrutide / Retatrutide

Welcome to Weekly Pep Talk — where GLP-1s, peptides, and longevity get real and judgment-free. Hosted by Prime Longevity Protocol, each episode covers semaglutide, tirzepatide, peptide therapy, biohacking, weight loss, metabolic health, and wellness optimization. Real talk for Warriors who refuse to settle for average. No shame. No gatekeeping. Just real people chasing real results. New episodes e... more

PublishesTwice weeklyEpisodes13Founded2 months ago
Number of ListenersCategories
Health & FitnessAlternative Health

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Artwork for Weekly Pep Talk

Latest Episodes

What happens when you combine peptides, fasting, brain optimization, and the future of medicine into one conversation?

In Episode 13 of Weekly Pep-Talk, Max and Mike dive into one of their most wide-ranging discussions yet, covering peptide protocol... more

What does “research use only” actually mean when it comes to peptides — and what are people getting wrong?

In this episode of Weekly Pep-Talk, Max and Mike Sheffer break down one of the most misunderstood topics in the peptide world: research-use pe... more

Are the peptides you’re buying actually real?

In this bonus episode of Weekly Pep-Talk, Max Plasencia and Mike Sheffer reveal the results of a real peptide testing experiment after purchasing peptides from 12 different overseas suppliers and sending... more

What’s the best peptide stack to get shredded for summer without losing muscle, energy, or your hair?

In Episode 10 of Pep-Talk, Max Plasencia and Mike Sheffer break down their ultimate summer shred peptide stacks, including Retatrutide, Tesamorelin... more

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Recent Guests

Alex Gibson
IFBB Pro, health coach
Physique Revival Coaching
Episode: Peptides for Muscle Growth, Fat Loss & Biohacking (Truth Explained)

Hosts

Max Plasencia
Host of Weekly Pep Talk; partner at the show's production umbrella
Mike Sheffer
Co-host and business partner, long-time collaborator on Weekly Pep Talk

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Talking Points

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Cancer Peptides, TRT & Longevity Hacks Q&A
Q: What menopause peptide protocol and dosages balance female hormones, improve sleep, and preserve athletic performance?
The panel outlines a menopause protocol including RENISHUTIDE (renishute tide? likely renishutide), MOTC, BPC, and NAD, with specific dosages (e.g., MOTC 5-10 mg/week, BPC 5 mg daily up to 1 mg; NAD 25-100 mg/day; CJC-IPA at low doses for post-balance optimization), and stresses sequencing (start with MOTC to rebalance ATP and mitochondrial function before adding other peptides).
Cancer Peptides, TRT & Longevity Hacks Q&A
Q: What are the best strategies or peptide stacks to help people with cancer, either to support treatment effectiveness, reduce side effects, or aid healing?
The speakers emphasize improving insulin sensitivity to create a less favorable environment for cancer, discuss using GLP-1 agonists like tirzepatide or semaglutide, mention TA1 (Thymosin Alpha-1) to boost NK cells, and suggest anti-inflammatory and immune-supporting peptides (e.g., BPC, KPV) as part of a broader, research-grounded approach, while noting the importance of personal research and medical consultation.
PNC-27 Cancer Peptide + Peptide Reconstitution Guide
Q: Can cancer survivors take peptides, and which ones should be avoided?
They discuss using PNC 27/28 and MOTC as potential options while highlighting the need to consider cancer status, and suggesting focusing on reducing sugar levels and supporting immune function rather than blindly adopting new peptides; they emphasize personal risk assessment and consulting professionals.

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Frequently Asked Questions About Weekly Pep Talk

What is Weekly Pep Talk about and what kind of topics does it cover?

This show consistently covers GLP-1s, peptides, and longevity through practical, real-world discussion. Episodes skew toward dosing strategies, safety, and long-term health, with deep dives into how compounds like semaglutide, tirzepatide, Tesamorelin, and various peptide therapies interact with metabolism, body composition, and recovery. A notable strength is the candid, experience-based approach: the hosts share client stories, lab-work habits, and practical stacking plans while emphasizing caution, medical oversight, and ethical considerations in a rapidly evolving field. The format often centers on actionable tips, regulatory and access issues, and a pro-user education stance, making it useful for listeners who want to understand not ju... more

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Which podcasts are similar to Weekly Pep Talk?

These podcasts share a similar audience with Weekly Pep Talk:

1. Motivation with Jon Andersen
2. GSD Mode Podcast
3. The Science of Age-less Living
4. Peptides Explained
5. Peptide of The Week

How many episodes of Weekly Pep Talk are there?

Weekly Pep Talk launched 2 months ago and published 13 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Weekly Pep Talk?

Recent guests on Weekly Pep Talk include:

1. Alex Gibson

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