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Artwork for Peptides Explained

Peptides Explained

John Garrett
Peptides
Bpc-157
Glp-1
Glp-1 Medications
Retatrutide
Semaglutide
Igf-1
Obesity
Cancer
Growth Hormone Secretagogues
Aging
Weight Loss
Cjc-1295
Ghk-Cu
Vesugen
FDA
Offline Peptides
AOD 9604
AMPK
NAD+

Peptides Explained breaks down the most talked-about peptides and GLP-1 medications in health, fitness, and longevity — including semaglutide, tirzepatide, BPC-157, TB-500, and more. Hosted by Registered Nurse John Garrett, this podcast explains how these compounds work, why they're popular, what the research shows, and the real risks and side effects — all in plain language. No bro science. No hy... more

PublishesDailyEpisodes66Founded9 months ago
Number of ListenersCategory
Health & Fitness

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Artwork for Peptides Explained

Latest Episodes

True-Sciences.com use code Pep20 for 20% off your first order

What if some of the most important discoveries in regenerative medicine come not from replacing damaged cells, but from understanding how cells communicate?

On this episode of Peptides... more

Weight loss is not the same thing as fat loss. A 2025 monkey study combining semaglutide with experimental myostatin and activin A antibodies raised the possibility of protecting lean mass while losing fat. Now COURAGE phase 2 data provide a human le... more

True-Sciences.com use code Pep20 for 20% off your first order

Dr. Hany Demian joins John Garrett for a conversation about chronic pain, injury recovery, regenerative medicine, and where peptides may fit in patient care.

Drawing on his clinical ex... more

BPC-157 is back in the compounding-policy conversation—but what does HHS's new notice actually change, and what does the human evidence show? In this revisit, John Garrett looks at BPC-157's proposed biology, the three small published human reports, ... more

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Recent Guests

Hany Demian
Physician working in chronic pain management and regenerative medicine
Episode: Where Do Peptides Fit in Pain and Recovery? | Dr. Hany Demian
Sanjiv Lal
Founder of Cell Factor and co-founder of Regen Therapy
Regen Therapy
Episode: Beyond Stem Cells: Secretomes, Cellular Repair & Longevity | Sanjiv Lal
Cherie Calbom
Whole Foods nutritionist, known as the Juice Lady, and author of The Truth About Seed Oils.
Episode: The Silent Killer in Your Kitchen? Seed Oils, Inflammation & What to Cook With Instead with Cherie Calbom
Paris Hilton
Celebrity guest promoting a Hilton Honors giveaway
Hilton Honors
Episode: Why Boomers Are Living Longer But Not Healthier: Where Peptides May Fit Into Healthy Aging
Nick Martinez
Individual sharing personal experience with psoriasis and peptide use
Self-described patient/peptide user
Episode: Epitalon Explained: The Science of Telomeres, Aging & Longevity
Matthew Pacheco
Founder of Offline Peptides
Offline Peptides
Episode: Inside the Peptide Industry: Quality, Testing, Regulation & Grey Market Peptides

Host

John Garrett
Host of Peptides Explained. Presents educational content about peptides and GLP-1 therapies with a focus on evidence and safety.

Reviews

4.7 out of 5 stars from 57 ratings
  • Life Changing

    This podcast has changed my life. I trust the information I get from this podcast like none other. I have used several peptides with success. I’ve lost weight. I quit drinking and I really listen to these episodes to get more informed because I want to understand peptide better. I can’t overstay how grateful I am for this podcast.

    Apple Podcasts
    5
    howlinmouse
    United States4 months ago
  • Very informative!

    John does a great job breaking down the peptide information so anyone can understand the future of personal wellness.

    Apple Podcasts
    5
    KyTechTeacher
    United States6 months ago
  • I’ve learned so much!

    Great information! Understanding peptides is overwhelming for me. Thank you for breaking it down and making it easy to understand.

    Apple Podcasts
    5
    JLG-JLG
    United States7 months ago
  • Good job

    Thanks for keeping it simple

    Apple Podcasts
    5
    Wgr217
    United States7 months ago
  • NP Approved!

    Thank you for your straight to the point info. Fellow nurse here and needing unbiased info for pts. Keep them coming… I’m listening 😁

    Apple Podcasts
    5
    mllrn
    United States7 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Listener-focused Q&A adds practical value for real-world decisions.
Respectful, measured tone and emphasis on safety and medical supervision.
Clear, evidence-based insights that help separate hype from data.
Accessible explanations make complex peptides understandable for non-experts.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Where Do Peptides Fit in Pain and Recovery? | Dr. Hany Demian
Q: You injected BPC157 straight into the spine for the back. All right? So you shared with me that you're in the middle of doing a study with intraarticular BPC157. Let's talk about that, because I know everybody that was listening, they were like, what? Straight into the joint? Can you do that?
Demian describes a study involving BPC-157 and TB injections for recent injuries and early arthritis, with imaging before and after treatment. He says participants had not previously received cortisone or PRP injections in the affected joints, and that the study results were being prepared for publication.
Where Do Peptides Fit in Pain and Recovery? | Dr. Hany Demian
Q: What do you feel like are the most important basics that someone needs to come in? Let's say a seeker comes into your office and they have type 2 diabetes, and I think that's one of the most common, and obesity together. What would you say to start off with, you know, as the basic essentials before getting into the peptides?
Demian recommends a thorough history, physical assessment, and blood work, including evaluation of diabetes-related damage, inflammation, sleep, habits, activity, and hormones. He advises starting with manageable improvements to sleep, diet, and exercise, then considering treatments such as GLP-1 medications or peptides according to the patient's needs.
Beyond Stem Cells: Secretomes, Cellular Repair & Longevity | Sanjiv Lal
Q: So with Cell Factor, are you guys doing the same thing that you experienced in Zurich? Are you coming up with custom therapies like you did for your kidneys with Cell Factor here in the United States?
Lal says the current product is broadly used and is not customized because manipulating cells could make it subject to drug regulations. He says the company intends to pursue regulatory pathways for future products targeted at particular organs.
Beyond Stem Cells: Secretomes, Cellular Repair & Longevity | Sanjiv Lal
Q: So what was the process? So you went over to, what was the country again that you went to?
Lal says he went to Zurich, where a lab isolated cell signaling material using bioreactors and hypoxic conditions. He explains that his company uses a related process in the United States, including isolating tissue compartments, freezing and lyophilizing the material.
The Silent Killer in Your Kitchen? Seed Oils, Inflammation & What to Cook With Instead with Cherie Calbom
Q: So what are some other tips, Cherie, that you could give the listeners today to make that transition? Aside from reading the labels, what are some basic good starting points to remove these oils from your diet and replace them with good ones?
Calbom suggested trying Seed Oil Scout to find restaurants and scan products, using seed-oil-free recipes, and downloading a free meal plan from her website.

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Frequently Asked Questions About Peptides Explained

What is Peptides Explained about and what kind of topics does it cover?

Science-forward discussions dissecting popular peptides and GLP-1 medications, focusing on how these compounds work, what research actually shows, and the real risks and side effects. Episodes balance real-world data with clinical context, offering practical guidance for anyone considering peptide therapies, from weight-management drugs to immune-modulating compounds. A standout trait is the commitment to clear, non-sensational education, with an emphasis on medical supervision and evidence quality rather than hype.

What makes it noteworthy is the consistent emphasis on critical evaluation of observational data, regulatory status, and safety, plus practical questions listeners can bring to clinicians. The host often engages directly with au... more

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Which podcasts are similar to Peptides Explained?

These podcasts share a similar audience with Peptides Explained:

1. Peptalk: Peptides Unpacked
2. Peptide of the Week Podcast
3. The Hunter Williams Podcast
4. The Peptide Podcast
5. Today's discussion

How many episodes of Peptides Explained are there?

Peptides Explained launched 9 months ago and published 66 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Peptides Explained?

Recent guests on Peptides Explained include:

1. Hany Demian
2. Sanjiv Lal
3. Cherie Calbom
4. Paris Hilton
5. Nick Martinez
6. Matthew Pacheco

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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