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The Upstarts Podcast

Alex Konrad
Artificial Intelligence
Upstarts Media
Alex Konrad
Space Energy Grid
Medicare
Canva
Loyal
Valar Atomics
Flexport
Tariffs
Harvey
Dog Longevity
Nuclear Energy
Synthesia
Technology
Lifespan Extension
Global Trade
Star Catcher Industries
Decagon
Generative AI

On The Upstarts Podcast, you’ll hear from some of the most exciting Upstarts today: emerging technology leaders punching above their weight to achieve real impact. Veteran tech reporter Alex Konrad profiled leaders from Marc Benioff to Melanie Perkins in a decade-plus at Forbes. Now as the founder and editor of Upstarts Media, he’s sitting down with breakout entrepreneurs taking on the status quo ... more

PublishesWeeklyEpisodes16Founded4 months ago
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BusinessTechnologyEntrepreneurship

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Latest Episodes

Ever since neurosurgeon Alex Ksendzovsky was in college, he’s been captivated by an idea worthy of a mad scientist: turning brain cell ‘wetware’ into ‘software’ that can make predictions and help train AI.

It sounds like science fiction, but at Ksen... more

When Vanta co-founder Christina Cacioppo first pitched investors on compliance software, she faced a frosty reception.

It wasn’t a viable product category, she was told. They’d sell for peanuts within a couple of months. No one actually wanted to wo... more

YouTube

If you could fix the genetic lottery to ensure your baby was born healthy, would you?

For entrepreneur Noor Siddiqui, there's no question. Ever since her mother started to lose her vision as the result of a genetic condition, she’s dreamed of solvin... more

YouTube

The ChatGPT craze was still years away when Chilean-born Cris Valenzuela co-founded Runway to tinker on visual AI models with two classmates at an NYU lab in 2018.

Back then, investors weren't sold — not just on video AI, but on generative AI altoge... more

YouTube

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Recent Guests

Noor Siddiqui
CEO of Orchid Health
Orchid Health
Episode: Orchid’s Noor Siddiqui: Rigging The Genetic Lottery To Create Healthier ‘Superbabies’
Cris Valenzuela
Co-founder and CEO of Runway
Runway
Episode: Runway’s Cris Valenzuela: Building The Hollywood-Friendly Video AI That OpenAI Couldn’t
Cobi Blumenfeld-Gantz
Co-founder and CEO of Chapter
Chapter
Episode: Chapter's Cobi Blumenfeld-Gantz: From Palantir To $3B Medicare Disruptor
Aidan Gomez
Co-founder and CEO of Cohere
Cohere
Episode: Cohere's Aidan Gomez: The Canadian Founder Taking AI Models To The World, Not Just Big Tech
Jesse Zhang
Co-founder and CEO of Decagon
Decagon
Episode: Decagon’s Jesse Zhang: Closing Customer Service Doom Loops With AI Concierges
Winston Weinberg
Co-founder and CEO of Harvey
Harvey
Episode: Harvey's Winston Weinberg: From Law Associate To $11 Billion Legal AI Startup CEO
Andrew Rush
Co-founder and CEO of Star Catcher Industries
Star Catcher Industries
Episode: Star Catcher’s Andrew Rush: Harnessing The Sun To Build The First Energy Grid In Space
Victor Riparbelli
Co-founder and CEO of Synthesia
Synthesia
Episode: Synthesia's Victor Riparbelli: Using AI To Replace Boring PowerPoints With Interactive Video
Ryan Petersen
Founder and CEO of Flexport
Flexport
Episode: Flexport’s Ryan Petersen: tech’s trade expert on solving tariff chaos with AI agents & winning again

Host

Alex Konrad
Host of The Upstarts Podcast

Reviews

5.0 out of 5 stars from 9 ratings
  • Great show!

    Huge fan of Upstarts Media, and Alex has done it again with this podcast. It’s an entertaining way to learn about the most exciting companies in tech, and it's quickly becoming my favorite industry podcast.

    Apple Podcasts
    5
    ekresse
    United States3 months ago
  • Inspiring

    I really enjoyed this show - it feels like a rare contribution to the space in that it combines a kind of scrappy, ‘let’s build something’ energy with great access to high-profile people. I found it really energizing

    Apple Podcasts
    5
    Histlover482
    United States4 months ago
  • All stars!

    Thrilled for this podcast release, from a great team already putting out great stories. Excited for this season!

    Apple Podcasts
    5
    NewArchivist
    United States4 months ago
  • Great listen!

    If you want to know about start up culture in the tech industry, this is the podcast for you.

    Apple Podcasts
    5
    zdroberts
    United States4 months ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Listeners praise access to high-profile guests and actionable insights for founders.
Audience notes strong storytelling and practical lessons for building and scaling tech businesses.
The show is seen as energizing and empowering, blending scrappy startup energy with serious industry knowledge.

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Talking Points

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Star Catcher’s Andrew Rush: Harnessing The Sun To Build The First Energy Grid In Space
Q: How does Star Catcher plan to reach orbital power at scale?
The company plans a crawl-walk-run path: seed ground demonstrations to reduce tech risk, followed by an A-round to perform tests in space, and then a B-round to scale operations, all built around a staged roadmap that gradually increases system complexity and capital needs.
Star Catcher’s Andrew Rush: Harnessing The Sun To Build The First Energy Grid In Space
Q: What is the core problem Star Catcher is solving for space operations?
The core problem is the power budget constraint for satellites; Star Catcher aims to beam highly concentrated energy to existing solar arrays, effectively increasing available power without needing to scale the satellite bus size, thereby increasing uptime and enabling more capable payloads.
Runway’s Cris Valenzuela: Building The Hollywood-Friendly Video AI That OpenAI Couldn’t
Q: So for people who are not familiar, what exactly is Runway and how do you describe it to people today?
Cris explains Runway as an applied AI research company that builds video and world models, training large video models and deploying them across entertainment, moviemaking, robotics, gaming, and more, with products built on top of these world models.
Loyal’s Celine Halioua: From Defying Doubters To Pioneering Dog Longevity
Q: What does it mean for Loyal to be both a deep tech and consumer-facing company?
We are built on rigorous, high-tech biology, but we operate with consumer accessibility in mind—pricing, outreach, and usability are designed for everyday dog owners and veterinarians, not just investors or scientists.
Loyal’s Celine Halioua: From Defying Doubters To Pioneering Dog Longevity
Q: Why adopt a portfolio approach to drugs instead of betting on a single program?
A portfolio approach mitigates biological and manufacturing risks; it hedges bets and protects the company from a single point of failure while advancing multiple avenues toward a safe and effective product for longevity.

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Frequently Asked Questions About The Upstarts Podcast

What is The Upstarts Podcast about and what kind of topics does it cover?

A design-focused tech and entrepreneurship interview series that features deep-dives with founders and chief executives building ambitious companies in AI, biotech, space, fintech, and enterprise software. Conversations typically explore origin stories, product strategy, go-to-market moves, and the regulatory or ethical considerations shaping emerging technologies. Noteworthy is a consistent emphasis on hands-on experimentation, long-term vision, and the founders' willingness to challenge incumbents, coupled with candid discussions about fundraising, partnerships, and navigating complex industries. The show often blends tactical lessons for builders with broader implications for industry, policy, and society, making it useful for listeners ... more

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The Upstarts Podcast launched 4 months ago and published 16 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Upstarts Podcast?

Recent guests on The Upstarts Podcast include:

1. Noor Siddiqui
2. Cris Valenzuela
3. Cobi Blumenfeld-Gantz
4. Aidan Gomez
5. Jesse Zhang
6. Winston Weinberg
7. Andrew Rush
8. Victor Riparbelli

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